JP2017507145A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017507145A5 JP2017507145A5 JP2016553402A JP2016553402A JP2017507145A5 JP 2017507145 A5 JP2017507145 A5 JP 2017507145A5 JP 2016553402 A JP2016553402 A JP 2016553402A JP 2016553402 A JP2016553402 A JP 2016553402A JP 2017507145 A5 JP2017507145 A5 JP 2017507145A5
- Authority
- JP
- Japan
- Prior art keywords
- delivery system
- substance delivery
- matrix
- polymeric material
- anabolic agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14000598.4 | 2014-02-20 | ||
| EP14000598 | 2014-02-20 | ||
| PCT/EP2015/053645 WO2015124739A1 (en) | 2014-02-20 | 2015-02-20 | Implant comprising fgf-18 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017507145A JP2017507145A (ja) | 2017-03-16 |
| JP2017507145A5 true JP2017507145A5 (https=) | 2018-02-22 |
| JP6510547B2 JP6510547B2 (ja) | 2019-05-08 |
Family
ID=50151086
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016553402A Active JP6510547B2 (ja) | 2014-02-20 | 2015-02-20 | Ｆｇｆ−１８を含むインプラント |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US10086112B2 (https=) |
| EP (1) | EP3107592B1 (https=) |
| JP (1) | JP6510547B2 (https=) |
| KR (1) | KR102421950B1 (https=) |
| CN (1) | CN106232154A (https=) |
| AR (1) | AR099556A1 (https=) |
| AU (1) | AU2015220785B2 (https=) |
| BR (1) | BR112016018681B1 (https=) |
| CA (1) | CA2938796C (https=) |
| DK (1) | DK3107592T3 (https=) |
| ES (1) | ES2698117T3 (https=) |
| HR (1) | HRP20181573T1 (https=) |
| IL (1) | IL247106B (https=) |
| LT (1) | LT3107592T (https=) |
| MX (1) | MX368946B (https=) |
| NZ (1) | NZ723177A (https=) |
| PL (1) | PL3107592T3 (https=) |
| PT (1) | PT3107592T (https=) |
| RS (1) | RS58138B1 (https=) |
| RU (1) | RU2700414C2 (https=) |
| SG (1) | SG11201606697YA (https=) |
| SI (1) | SI3107592T1 (https=) |
| WO (1) | WO2015124739A1 (https=) |
| ZA (1) | ZA201605667B (https=) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2959509B1 (en) | 2013-02-14 | 2018-05-23 | Nanopareil, Llc | Electrospun hybrid nanofibre felt, method for making the same, and method for purifying biomolecules |
| HUE040350T2 (hu) | 2014-02-20 | 2019-03-28 | Merck Patent Gmbh | FGF-18 vegyületadagoló étrend |
| AU2016211950A1 (en) | 2015-01-29 | 2017-07-13 | Ares Trading S.A. | Immunoassays for high positively charged proteins |
| IL273613B2 (en) | 2017-09-29 | 2026-02-01 | Merck Patent Gmbh | Metabolic biomarkers for predicting response to FGF-18 compound |
| SI3688468T1 (sl) | 2017-09-29 | 2022-08-31 | Merck Patent Gmbh | Vnetni biomarkerji za predvidevanje odzivov na spojino FGF-18 |
| IL281333B2 (en) | 2018-09-10 | 2025-11-01 | Merck Patent Gmbh | A method for reducing risk in a clinical trial |
| CN117187255B (zh) * | 2023-11-07 | 2024-01-30 | 北京大学第三医院（北京大学第三临床医学院） | 编码FGF18或rhFGF18的mRNA及其在骨关节炎治疗中的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6511958B1 (en) | 1997-08-14 | 2003-01-28 | Sulzer Biologics, Inc. | Compositions for regeneration and repair of cartilage lesions |
| EP0896825B1 (en) * | 1997-08-14 | 2002-07-17 | Sulzer Innotec Ag | Composition and device for in vivo cartilage repair comprising nanocapsules with osteoinductive and/or chondroinductive factors |
| KR100380119B1 (ko) * | 2001-04-19 | 2003-04-11 | 한국항공우주연구원 | 이원화된 통신속도 적응형 베이스 밴드 스위칭 위상시프트 키잉 장치 |
| EP1273365A1 (fr) * | 2001-07-06 | 2003-01-08 | Recherche Et Developpement Du Groupe Cockerill Sambre | Outils rotatifs pour le perçage en ligne de produits profiles |
| ES2493840T3 (es) * | 2002-10-07 | 2014-09-12 | Zymogenetics, Inc. | Procedimiento de administración de FGF-18 |
| US8852240B2 (en) | 2004-10-25 | 2014-10-07 | Kieran Murphy, Llc | Methods and compositions for fostering and preserving bone growth |
| AU2005314438B2 (en) * | 2004-12-10 | 2012-03-29 | Zymogenetics, Inc. | FGF18 production in prokaryotic hosts |
| MY148277A (en) * | 2006-08-25 | 2013-03-29 | Ares Trading Sa | Treatment of cartilage disorders with fgf-18 |
| JP2012519556A (ja) * | 2009-03-05 | 2012-08-30 | バイオミメティック セラピューティクス， インコーポレイテッド | 骨軟骨欠損を治療するための血小板由来増殖因子組成物および方法 |
| US8431399B2 (en) * | 2010-03-02 | 2013-04-30 | Taipei Medical University | Method to restore cartilaginous phenotype of chondrocytes after cultured and expanded in vitro |
| US10130687B2 (en) * | 2011-01-05 | 2018-11-20 | Rhode Island Hospital | Compositions and methods for the treatment of orthopedic disease or injury |
| WO2012113812A1 (en) * | 2011-02-22 | 2012-08-30 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Nano-reservoirs technology for use in bone and/or cartilage regeneration |
| ES2806026T3 (es) * | 2013-12-24 | 2021-02-16 | Ares Trading Sa | Formulación de FGF-18 en hidrogeles de alginato/colágeno |
| HUE040350T2 (hu) | 2014-02-20 | 2019-03-28 | Merck Patent Gmbh | FGF-18 vegyületadagoló étrend |
| MX2016010873A (es) | 2014-02-20 | 2016-11-17 | Merck Patent Gmbh | Factor de crecimiento de fibroblastos 18 en los procedimientos para el trasplante de injertos y para ingenieria de tejidos. |
-
2015
- 2015-02-20 JP JP2016553402A patent/JP6510547B2/ja active Active
- 2015-02-20 AR ARP150100505A patent/AR099556A1/es not_active Application Discontinuation
- 2015-02-20 CA CA2938796A patent/CA2938796C/en active Active
- 2015-02-20 BR BR112016018681-8A patent/BR112016018681B1/pt active IP Right Grant
- 2015-02-20 NZ NZ723177A patent/NZ723177A/en unknown
- 2015-02-20 AU AU2015220785A patent/AU2015220785B2/en active Active
- 2015-02-20 WO PCT/EP2015/053645 patent/WO2015124739A1/en not_active Ceased
- 2015-02-20 RS RS20181404A patent/RS58138B1/sr unknown
- 2015-02-20 LT LTEP15706011.2T patent/LT3107592T/lt unknown
- 2015-02-20 US US15/120,137 patent/US10086112B2/en active Active
- 2015-02-20 PL PL15706011T patent/PL3107592T3/pl unknown
- 2015-02-20 PT PT15706011T patent/PT3107592T/pt unknown
- 2015-02-20 KR KR1020167025247A patent/KR102421950B1/ko active Active
- 2015-02-20 SG SG11201606697YA patent/SG11201606697YA/en unknown
- 2015-02-20 DK DK15706011.2T patent/DK3107592T3/en active
- 2015-02-20 CN CN201580020527.3A patent/CN106232154A/zh active Pending
- 2015-02-20 MX MX2016010874A patent/MX368946B/es active IP Right Grant
- 2015-02-20 RU RU2016137291A patent/RU2700414C2/ru active
- 2015-02-20 EP EP15706011.2A patent/EP3107592B1/en active Active
- 2015-02-20 ES ES15706011T patent/ES2698117T3/es active Active
- 2015-02-20 HR HRP20181573TT patent/HRP20181573T1/hr unknown
- 2015-02-20 SI SI201530409T patent/SI3107592T1/sl unknown
-
2016
- 2016-08-04 IL IL247106A patent/IL247106B/en active IP Right Grant
- 2016-08-16 ZA ZA2016/05667A patent/ZA201605667B/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017507145A5 (https=) | ||
| Haggerty et al. | Biomaterials for revascularization and immunomodulation after spinal cord injury | |
| RU2016137291A (ru) | Имплантат, содержащий fgf-18 | |
| JP2014240439A5 (https=) | ||
| JP2014139220A5 (https=) | ||
| MX384527B (es) | Compuestos derivados de oxadiazolamina como inhibidores de histona desacetilasa 6, y la composición farmacéutica que comprende los mismos | |
| JP2017512194A5 (https=) | ||
| JP2017507142A5 (https=) | ||
| NZ707328A (en) | Virus-containing formulation and use thereof | |
| RU2016137292A (ru) | Схема применения соединения fgf-18 | |
| JP2016517888A5 (https=) | ||
| JP2017501140A5 (https=) | ||
| JP2009017881A5 (https=) | ||
| JP2017522288A5 (https=) | ||
| JP2011225596A5 (https=) | ||
| WO2021034958A3 (en) | Materials for delivery of tetherable proteins in bone implants | |
| JP2017105861A5 (https=) | ||
| JP2017513809A5 (https=) | ||
| JP2018521643A5 (https=) | ||
| JP2017105862A5 (https=) | ||
| JP2017105859A5 (https=) | ||
| HRP20180061T1 (hr) | Indolkarbonitrili kao selektivni modulatori androgenskih receptora | |
| NZ729628A (en) | Methods for the treatment of peri-implantitis | |
| EP4474012A3 (en) | Melatonin mini-tablets and method of manufacturing the same | |
| JP2017502058A5 (https=) |