JP2017506511A5 - - Google Patents
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- JP2017506511A5 JP2017506511A5 JP2016551725A JP2016551725A JP2017506511A5 JP 2017506511 A5 JP2017506511 A5 JP 2017506511A5 JP 2016551725 A JP2016551725 A JP 2016551725A JP 2016551725 A JP2016551725 A JP 2016551725A JP 2017506511 A5 JP2017506511 A5 JP 2017506511A5
- Authority
- JP
- Japan
- Prior art keywords
- medium
- ldl
- mesenchymal stem
- medium according
- lipoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 239000002609 medium Substances 0.000 claims 24
- 108010007622 LDL Lipoproteins Proteins 0.000 claims 7
- 102000007330 LDL Lipoproteins Human genes 0.000 claims 7
- 210000002901 mesenchymal stem cell Anatomy 0.000 claims 7
- 102000018233 Fibroblast Growth Factor Human genes 0.000 claims 4
- 108050007372 Fibroblast Growth Factor Proteins 0.000 claims 4
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 claims 4
- 108010062497 VLDL Lipoproteins Proteins 0.000 claims 4
- 229940126864 fibroblast growth factor Drugs 0.000 claims 4
- 239000001963 growth medium Substances 0.000 claims 4
- 239000002245 particle Substances 0.000 claims 4
- 102000004895 Lipoproteins Human genes 0.000 claims 3
- 108090001030 Lipoproteins Proteins 0.000 claims 3
- 102000004887 Transforming Growth Factor beta Human genes 0.000 claims 3
- 108090001012 Transforming Growth Factor beta Proteins 0.000 claims 3
- 102000003974 Fibroblast growth factor 2 Human genes 0.000 claims 2
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 claims 2
- 108010010234 HDL Lipoproteins Proteins 0.000 claims 2
- 102000015779 HDL Lipoproteins Human genes 0.000 claims 2
- 108010046315 IDL Lipoproteins Proteins 0.000 claims 2
- 102000009618 Transforming Growth Factors Human genes 0.000 claims 2
- 108010009583 Transforming Growth Factors Proteins 0.000 claims 2
- 239000007640 basal medium Substances 0.000 claims 2
- 238000000034 method Methods 0.000 claims 2
- 108091008012 small dense LDL Proteins 0.000 claims 2
- ZRKFYGHZFMAOKI-QMGMOQQFSA-N tgfbeta Chemical compound C([C@H](NC(=O)[C@H](C(C)C)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CCSC)C(C)C)[C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(O)=O)C1=CC=C(O)C=C1 ZRKFYGHZFMAOKI-QMGMOQQFSA-N 0.000 claims 2
- 102000008100 Human Serum Albumin Human genes 0.000 claims 1
- 108091006905 Human Serum Albumin Proteins 0.000 claims 1
- 108010033266 Lipoprotein(a) Proteins 0.000 claims 1
- 102000057248 Lipoprotein(a) Human genes 0.000 claims 1
- 210000000577 adipose tissue Anatomy 0.000 claims 1
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 210000000845 cartilage Anatomy 0.000 claims 1
- 238000012258 culturing Methods 0.000 claims 1
- UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
- 229960003957 dexamethasone Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 229910052711 selenium Inorganic materials 0.000 claims 1
- 239000011669 selenium Substances 0.000 claims 1
- 239000012679 serum free medium Substances 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 claims 1
- 230000002792 vascular Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14155263.8 | 2014-02-14 | ||
| EP14155263 | 2014-02-14 | ||
| PCT/EP2015/053223 WO2015121471A1 (en) | 2014-02-14 | 2015-02-16 | Serum-free medium |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017506511A JP2017506511A (ja) | 2017-03-09 |
| JP2017506511A5 true JP2017506511A5 (https=) | 2017-11-16 |
Family
ID=50101793
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016551725A Ceased JP2017506511A (ja) | 2014-02-14 | 2015-02-16 | 無血清培地 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US10472605B2 (https=) |
| EP (1) | EP3074505B1 (https=) |
| JP (1) | JP2017506511A (https=) |
| CN (1) | CN106062179A (https=) |
| WO (1) | WO2015121471A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102676761B1 (ko) * | 2015-12-03 | 2024-06-18 | 다카라 바이오 가부시키가이샤 | 중간엽 줄기세포의 제조방법 |
| CN111349604B (zh) | 2016-05-18 | 2023-12-12 | 学校法人庆应义塾 | 类器官培养用细胞培养基、培养方法及类器官 |
| CN112322580B (zh) * | 2017-04-28 | 2022-03-22 | 北京赛斯达生物技术有限公司 | 一种间充质干细胞无血清培养基的应用 |
| KR102144593B1 (ko) * | 2017-06-07 | 2020-08-13 | 주식회사 엑소스템텍 | 인간줄기세포 유래 엑소좀을 포함하는 세포 배양용 무혈청 배지 조성물 |
| RU2020113411A (ru) * | 2017-10-20 | 2021-11-22 | Боун Терапьютикс Са | Способы дифференцировки мезенхимальных стволовых клеток |
| WO2020007878A1 (en) * | 2018-07-03 | 2020-01-09 | Universidad Del País Vasco - Euskal Herriko Unibertsitatea | Cellular aggregates for use in vascularisation therapy |
| KR102337954B1 (ko) * | 2018-08-16 | 2021-12-10 | 차의과학대학교 산학협력단 | 뇌졸중 치료용 조성물 및 이를 스크리닝하는 방법 |
| US20210024882A1 (en) * | 2019-07-08 | 2021-01-28 | Life Technologies Corporation | Compositions and methods for enhancing cell culture |
| CN114286860A (zh) * | 2019-08-29 | 2022-04-05 | 味之素株式会社 | 由含有间充质干细胞的生物来源细胞试样制造间充质干细胞的方法 |
| JP2021040551A (ja) * | 2019-09-11 | 2021-03-18 | 富士フイルム株式会社 | 培地組成物、キット、間葉系幹細胞組成物の製造方法、間葉系幹細胞組成物、間葉系幹細胞、細胞培養上清および細胞外小胞 |
| CN112342181B (zh) * | 2020-03-26 | 2021-12-24 | 中国人民解放军总医院第四医学中心 | 基于数控激光辐射的非入侵式的细胞成图案方法及系统 |
| JP7521738B2 (ja) * | 2020-05-18 | 2024-07-24 | キヤノン株式会社 | 目的細胞の生産方法、目的細胞による生産物の生産方法、および無血清培地 |
| CN113621567B (zh) * | 2021-07-09 | 2024-01-30 | 生物岛实验室 | 组合物及其应用、干细胞培养基及干细胞的培养方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS61277623A (ja) * | 1985-05-10 | 1986-12-08 | マイルス・ラボラトリ−ス・インコ−ポレ−テツド | 哺乳動物の血漿または血清あるいはその分画からコレステロールに富んだ分画を単離しかつ精製する方法 |
| US5908782A (en) * | 1995-06-05 | 1999-06-01 | Osiris Therapeutics, Inc. | Chemically defined medium for human mesenchymal stem cells |
| WO1998004681A2 (en) | 1996-07-25 | 1998-02-05 | Genzyme Corporation | Chondrocyte media formulations and culture procedures |
| TWI239352B (en) | 1997-07-23 | 2005-09-11 | Takara Bio Inc | Gene transfer method with the use of serum-free medium |
| DE60037819T2 (de) | 1999-08-27 | 2009-01-08 | Invitrogen Corp., Carlsbad | Metallbindende verbindungen und deren verwendung in zusammensetzungen für zellkulturmedien |
| ATE464373T1 (de) | 2001-12-21 | 2010-04-15 | Mount Sinai Hospital Corp | Zelluläre zusammensetzungen und verfahren zur deren bereitung und verwendung |
| JP2007536936A (ja) | 2004-05-14 | 2007-12-20 | ベクトン・ディキンソン・アンド・カンパニー | 幹細胞集団および使用方法 |
| US9074176B2 (en) | 2006-01-13 | 2015-07-07 | Two Cells Co., Ltd. | Culture medium additive for use in serum-free culturing of animal cell, kit and use thereof |
| EP2545928B1 (en) | 2010-03-10 | 2016-07-20 | Two Cells Co., Ltd | Cell preparation containing mesenchymal stem cells, and method for producing same |
| GB201117469D0 (en) * | 2011-10-10 | 2011-11-23 | Cell Guidance Systems Ltd | Culture media for pluripotent stem cells |
-
2015
- 2015-02-16 EP EP15707303.2A patent/EP3074505B1/en active Active
- 2015-02-16 JP JP2016551725A patent/JP2017506511A/ja not_active Ceased
- 2015-02-16 WO PCT/EP2015/053223 patent/WO2015121471A1/en not_active Ceased
- 2015-02-16 CN CN201580008299.8A patent/CN106062179A/zh active Pending
- 2015-02-16 US US15/118,569 patent/US10472605B2/en active Active
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