JP2017506228A - セロトニン放出ホルモン、アドレナリン放出ホルモン、ノルアドレナリン放出ホルモン、グルタミン酸放出ホルモンおよび副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのマイクロrnaおよび該マイクロrnaを含む組成物 - Google Patents
セロトニン放出ホルモン、アドレナリン放出ホルモン、ノルアドレナリン放出ホルモン、グルタミン酸放出ホルモンおよび副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのマイクロrnaおよび該マイクロrnaを含む組成物 Download PDFInfo
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/111—General methods applicable to biologically active non-coding nucleic acids
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- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
- C12N2310/141—MicroRNAs, miRNAs
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2320/00—Applications; Uses
- C12N2320/30—Special therapeutic applications
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
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- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
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- Biochemistry (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461935912P | 2014-02-05 | 2014-02-05 | |
| US61/935,912 | 2014-02-05 | ||
| PCT/IL2015/050132 WO2015118537A2 (en) | 2014-02-05 | 2015-02-05 | Micro-rnas and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019114138A Division JP2019172696A (ja) | 2014-02-05 | 2019-06-19 | セロトニン放出ホルモン、アドレナリン放出ホルモン、ノルアドレナリン放出ホルモン、グルタミン酸放出ホルモンおよび副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのマイクロrnaおよび該マイクロrnaを含む組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017506228A true JP2017506228A (ja) | 2017-03-02 |
| JP2017506228A5 JP2017506228A5 (enExample) | 2018-03-15 |
Family
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Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016549799A Pending JP2017506228A (ja) | 2014-02-05 | 2015-02-05 | セロトニン放出ホルモン、アドレナリン放出ホルモン、ノルアドレナリン放出ホルモン、グルタミン酸放出ホルモンおよび副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのマイクロrnaおよび該マイクロrnaを含む組成物 |
| JP2019114138A Pending JP2019172696A (ja) | 2014-02-05 | 2019-06-19 | セロトニン放出ホルモン、アドレナリン放出ホルモン、ノルアドレナリン放出ホルモン、グルタミン酸放出ホルモンおよび副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのマイクロrnaおよび該マイクロrnaを含む組成物 |
| JP2020180055A Pending JP2021020951A (ja) | 2014-02-05 | 2020-10-28 | セロトニン放出ホルモン、アドレナリン放出ホルモン、ノルアドレナリン放出ホルモン、グルタミン酸放出ホルモンおよび副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのマイクロrnaおよび該マイクロrnaを含む組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019114138A Pending JP2019172696A (ja) | 2014-02-05 | 2019-06-19 | セロトニン放出ホルモン、アドレナリン放出ホルモン、ノルアドレナリン放出ホルモン、グルタミン酸放出ホルモンおよび副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのマイクロrnaおよび該マイクロrnaを含む組成物 |
| JP2020180055A Pending JP2021020951A (ja) | 2014-02-05 | 2020-10-28 | セロトニン放出ホルモン、アドレナリン放出ホルモン、ノルアドレナリン放出ホルモン、グルタミン酸放出ホルモンおよび副腎皮質刺激ホルモン放出ホルモン関連の医学的状態の処置および診断のためのマイクロrnaおよび該マイクロrnaを含む組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US10125365B2 (enExample) |
| EP (1) | EP3102679B1 (enExample) |
| JP (3) | JP2017506228A (enExample) |
| CN (2) | CN106715695B (enExample) |
| CA (1) | CA2936158C (enExample) |
| IL (1) | IL246942B (enExample) |
| WO (1) | WO2015118537A2 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11680263B2 (en) | 2014-02-05 | 2023-06-20 | Yeda Research And Development Co. Ltd. | Micro-RNAS and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions |
| US12016876B2 (en) | 2011-08-04 | 2024-06-25 | Research And Development Co. Ltd. | Micro-RNAs and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018151135A1 (ja) * | 2017-02-15 | 2018-08-23 | 国立研究開発法人医薬基盤・健康・栄養研究所 | 精神疾患モデル動物およびその製造方法 |
| CN111566212A (zh) | 2017-11-03 | 2020-08-21 | 因特尔纳技术有限公司 | miRNA分子,等同物,安塔够妙或其来源用于治疗和/或诊断与神经元缺陷相关的病症和/或疾病或用于神经元生成和/或再生 |
| EP3720434A4 (en) | 2017-12-05 | 2021-09-01 | Sunovion Pharmaceuticals Inc. | NON-RACEMIC MIXTURES AND THEIR USES |
| CN112236138B (zh) | 2017-12-05 | 2024-05-31 | 赛诺维信制药公司 | 晶体形式及其制备方法 |
| CN108409851B (zh) * | 2018-01-29 | 2020-12-08 | 上海交通大学 | 肾细胞癌中高水平表达的蛋白及其应用 |
| CA3019970A1 (en) * | 2018-10-05 | 2020-04-05 | Fang Liu | Methods for diagnosing or treating post-traumatic stress disorder, and compositions therefor |
| TWI703218B (zh) * | 2019-01-19 | 2020-09-01 | 高雄榮民總醫院 | 生物標記用以診斷第二型雙極症的用途 |
| MX2021014774A (es) | 2019-06-04 | 2022-02-03 | Sunovion Pharmaceuticals Inc | Formulaciones de liberacion modificada y usos de las mismas. |
| US20220340870A1 (en) * | 2019-09-10 | 2022-10-27 | The Board Of Trustees Of The Leland Stanford Junior University | Functional neuromodulatory assembloids |
| CN110585197B (zh) * | 2019-09-26 | 2023-02-17 | 上海交通大学 | 多巴胺受体拮抗剂泰尔登在治疗急性髓系白血病中的应用 |
| CN111172274B (zh) * | 2020-01-22 | 2021-10-15 | 清华大学 | Synaptotagmin-7在双向情感障碍诊断和治疗中的用途 |
| CN111440861B (zh) * | 2020-04-01 | 2022-11-04 | 上海市精神卫生中心(上海市心理咨询培训中心) | 甲基化的miR-124基因在制备用于诊断抑郁症的标志物中的用途 |
| JP2024503711A (ja) * | 2021-01-18 | 2024-01-26 | イェダ リサーチ アンド デベロップメント カンパニー リミテッド | 修飾miR-135、そのコンジュゲートおよびその使用 |
| KR102570458B1 (ko) * | 2021-01-21 | 2023-08-24 | 전남대학교산학협력단 | 여성의 우울증 위험도 예측용 바이오마커, 상기 바이오마커를 이용한 여성의 우울증 위험도 진단에 대한 정보제공방법 및 진단키트 |
| JP7748047B2 (ja) * | 2021-08-23 | 2025-10-02 | 国立研究開発法人産業技術総合研究所 | 唾液中のうつ病バイオマーカー |
| CN114292851B (zh) * | 2022-01-12 | 2023-08-08 | 徐州医科大学 | 抑制Cnr1基因表达的干扰序列、shRNA慢病毒载体及构建方法和应用 |
| CN117737246B (zh) * | 2024-02-01 | 2025-01-28 | 首都医科大学附属北京天坛医院 | Plcb1基因作为生物标志物在侵袭性垂体腺瘤中的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013018060A2 (en) * | 2011-08-04 | 2013-02-07 | Yeda Research And Development Co. Ltd. | Micro-rnas and compositions comprising same for the treatment and diagnosis of serotonin-, adrenalin-, noradrenalin-, glutamate-, and corticotropin-releasing hormone- associated medical conditions |
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| US10125365B2 (en) | 2018-11-13 |
| BR112016018145A2 (pt) | 2018-02-20 |
| US11680263B2 (en) | 2023-06-20 |
| US10975373B2 (en) | 2021-04-13 |
| US20190055561A1 (en) | 2019-02-21 |
| IL246942B (en) | 2020-11-30 |
| WO2015118537A3 (en) | 2015-10-01 |
| WO2015118537A2 (en) | 2015-08-13 |
| CN106715695A (zh) | 2017-05-24 |
| CA2936158C (en) | 2023-06-13 |
| US20210230597A1 (en) | 2021-07-29 |
| IL246942A0 (en) | 2016-09-29 |
| US20160348101A1 (en) | 2016-12-01 |
| CN111733231A (zh) | 2020-10-02 |
| EP3102679B1 (en) | 2022-11-30 |
| CA2936158A1 (en) | 2015-08-13 |
| JP2019172696A (ja) | 2019-10-10 |
| EP3102679A2 (en) | 2016-12-14 |
| JP2021020951A (ja) | 2021-02-18 |
| CN106715695B (zh) | 2020-07-31 |
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