JP2017505779A5 - - Google Patents

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Publication number
JP2017505779A5
JP2017505779A5 JP2016549488A JP2016549488A JP2017505779A5 JP 2017505779 A5 JP2017505779 A5 JP 2017505779A5 JP 2016549488 A JP2016549488 A JP 2016549488A JP 2016549488 A JP2016549488 A JP 2016549488A JP 2017505779 A5 JP2017505779 A5 JP 2017505779A5
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JP
Japan
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pharmaceutically acceptable
acceptable salt
compound
alkyl
compound according
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JP2016549488A
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English (en)
Japanese (ja)
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JP2017505779A (ja
JP6619741B2 (ja
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Priority claimed from PCT/US2015/013263 external-priority patent/WO2015116663A1/en
Publication of JP2017505779A publication Critical patent/JP2017505779A/ja
Publication of JP2017505779A5 publication Critical patent/JP2017505779A5/ja
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JP2016549488A 2014-01-29 2015-01-28 タンパク質凝集の阻害剤としてのヘテロアリールアミド Active JP6619741B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461933246P 2014-01-29 2014-01-29
US61/933,246 2014-01-29
US201462078895P 2014-11-12 2014-11-12
US62/078,895 2014-11-12
PCT/US2015/013263 WO2015116663A1 (en) 2014-01-29 2015-01-28 Heteroarly amides as inhibitors of protein aggregation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019104159A Division JP6783900B2 (ja) 2014-01-29 2019-06-04 タンパク質凝集の阻害剤としてのヘテロアリールアミド

Publications (3)

Publication Number Publication Date
JP2017505779A JP2017505779A (ja) 2017-02-23
JP2017505779A5 true JP2017505779A5 (https=) 2018-02-22
JP6619741B2 JP6619741B2 (ja) 2019-12-11

Family

ID=52484559

Family Applications (2)

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JP2016549488A Active JP6619741B2 (ja) 2014-01-29 2015-01-28 タンパク質凝集の阻害剤としてのヘテロアリールアミド
JP2019104159A Active JP6783900B2 (ja) 2014-01-29 2019-06-04 タンパク質凝集の阻害剤としてのヘテロアリールアミド

Family Applications After (1)

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JP2019104159A Active JP6783900B2 (ja) 2014-01-29 2019-06-04 タンパク質凝集の阻害剤としてのヘテロアリールアミド

Country Status (38)

Country Link
US (3) US9738635B2 (https=)
EP (2) EP3348556B1 (https=)
JP (2) JP6619741B2 (https=)
KR (1) KR102383038B1 (https=)
CN (2) CN106132960B (https=)
AP (1) AP2016009347A0 (https=)
AU (1) AU2015211119B2 (https=)
BR (2) BR112016017344B1 (https=)
CA (1) CA2937967C (https=)
CL (1) CL2016001918A1 (https=)
CR (1) CR20160394A (https=)
CY (2) CY1120348T1 (https=)
DK (2) DK3099684T3 (https=)
EA (1) EA032374B1 (https=)
EC (1) ECSP16070327A (https=)
ES (2) ES2808978T3 (https=)
HK (1) HK1231470A1 (https=)
HR (2) HRP20180813T1 (https=)
HU (2) HUE040274T2 (https=)
IL (1) IL246987B (https=)
LT (2) LT3099684T (https=)
ME (1) ME03800B (https=)
MX (1) MX2016009896A (https=)
MY (1) MY187450A (https=)
NZ (1) NZ722487A (https=)
PE (1) PE20161393A1 (https=)
PH (1) PH12016501493B1 (https=)
PL (2) PL3348556T3 (https=)
PT (2) PT3099684T (https=)
RS (2) RS60547B1 (https=)
SA (1) SA516371579B1 (https=)
SG (1) SG11201606108RA (https=)
SI (2) SI3099684T1 (https=)
SM (2) SMT201800318T1 (https=)
TR (1) TR201809440T4 (https=)
UA (1) UA118209C2 (https=)
WO (1) WO2015116663A1 (https=)
ZA (1) ZA201605246B (https=)

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EA032374B1 (ru) 2014-01-29 2019-05-31 ЮСиБи БАЙОФАРМА СПРЛ Гетероарильные амиды в качестве ингибиторов агрегации белков
ES2885049T3 (es) 2015-07-29 2021-12-13 UCB Biopharma SRL Derivados de bis-heteroarilo como moduladores de la agregación de proteínas
CN107625767A (zh) * 2016-11-25 2018-01-26 刘淑兰 一种治疗慢性盆腔炎的药物
WO2018119142A1 (en) 2016-12-21 2018-06-28 Amgen Inc. Anti-tnf alpha antibody formulations
CN110167937B (zh) * 2017-01-26 2022-03-29 Ucb生物制药私人有限公司 作为蛋白质聚集调节剂的二环双-杂芳基衍生物
US10913735B2 (en) 2017-01-26 2021-02-09 UCB Biopharma SRL Bis-heteroaryl derivatives as modulators of protein aggregation
WO2018138085A1 (en) 2017-01-26 2018-08-02 Ucb Biopharma Sprl Alkoxy bis-heteroaryl derivatives as modulators of protein aggregation
JP7283699B2 (ja) * 2017-05-12 2023-05-30 マックス－プランク－ゲゼルシャフト・ツア・フェルデルング・デア・ヴィッセンシャフテン・エー・ファオ 黒色腫の治療または予防において使用するためのフェニル－ヘテロ環－フェニル誘導体
US11505528B2 (en) 2017-08-04 2022-11-22 Axial Therapeutics, Inc. Inhibitors of microbially induced amyloid
WO2019089640A1 (en) * 2017-10-31 2019-05-09 Loma Linda University Methods for treating traumatic brain injury
EP3841100A1 (en) 2018-08-20 2021-06-30 Arvinas Operations, Inc. Proteolysis targeting chimeric (protac) compound with e3 ubiquitin ligase binding activity and targeting alpha-synuclein protein for treating neurodegenerative diseases
US20250074902A1 (en) 2021-12-27 2025-03-06 Shanghai Jingxin Biomedical Co., Ltd. Fused bicyclic heteroaryl amide compound as protein aggregation inhibitor
GB202213796D0 (en) * 2022-09-21 2022-11-02 Wista Lab Ltd Tau aggregation inhibitors
CN120265630A (zh) * 2022-11-02 2025-07-04 Ac免疫有限公司 用于诊断tdp-43蛋白质病的新化合物
WO2024184180A1 (en) 2023-03-06 2024-09-12 UCB Biopharma SRL Minzasolmin for use in the treatment of parkinson's disease
WO2024184179A1 (en) 2023-03-06 2024-09-12 UCB Biopharma SRL Minzasolmin for use in the treatment of parkinson's disease
CN121487929A (zh) * 2023-06-25 2026-02-06 上海京新生物医药有限公司 双环杂芳基酰胺化合物的晶型及盐、制备方法和用途

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BR0316680A (pt) * 2002-11-28 2005-10-18 Schering Ag Pirimidinas inibidoras de chk, pdk e akt, sua produção e uso como agentes farmacêuticos
CN101385722A (zh) * 2003-02-27 2009-03-18 乔安妮·麦克劳林 预防、治疗和诊断蛋白聚集疾病的方法
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CA2867175A1 (en) 2012-03-28 2013-10-03 Neuropore Therapies, Inc. Phenyl-urea and phenyl-carbamate derivatives as inhibitors of protein aggregation
ES2661394T3 (es) 2012-07-16 2018-03-28 Neuropore Therapies, Inc. Derivados de di- y tri-heteroarilo como inhibidores de la agregación de proteínas
EA032374B1 (ru) 2014-01-29 2019-05-31 ЮСиБи БАЙОФАРМА СПРЛ Гетероарильные амиды в качестве ингибиторов агрегации белков
ES2885049T3 (es) 2015-07-29 2021-12-13 UCB Biopharma SRL Derivados de bis-heteroarilo como moduladores de la agregación de proteínas
CN110167937B (zh) 2017-01-26 2022-03-29 Ucb生物制药私人有限公司 作为蛋白质聚集调节剂的二环双-杂芳基衍生物
US10913735B2 (en) 2017-01-26 2021-02-09 UCB Biopharma SRL Bis-heteroaryl derivatives as modulators of protein aggregation

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