JP2017500024A5 - - Google Patents
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- JP2017500024A5 JP2017500024A5 JP2016536954A JP2016536954A JP2017500024A5 JP 2017500024 A5 JP2017500024 A5 JP 2017500024A5 JP 2016536954 A JP2016536954 A JP 2016536954A JP 2016536954 A JP2016536954 A JP 2016536954A JP 2017500024 A5 JP2017500024 A5 JP 2017500024A5
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- JP
- Japan
- Prior art keywords
- seq
- acid sequence
- amino acid
- polypeptide
- nucleic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361911759P | 2013-12-04 | 2013-12-04 | |
| US61/911,759 | 2013-12-04 | ||
| US201462050399P | 2014-09-15 | 2014-09-15 | |
| US62/050,399 | 2014-09-15 | ||
| PCT/CA2014/051164 WO2015081437A1 (en) | 2013-12-04 | 2014-12-03 | Compositions and methods for making (r)-reticuline and precursors thereof |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017500024A JP2017500024A (ja) | 2017-01-05 |
| JP2017500024A5 true JP2017500024A5 (cg-RX-API-DMAC10.html) | 2020-01-30 |
| JP6783655B2 JP6783655B2 (ja) | 2020-11-11 |
Family
ID=53272687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016536954A Active JP6783655B2 (ja) | 2013-12-04 | 2014-12-03 | （ｒ）−レチクリンおよびその前駆体を製造するための組成物および方法 |
Country Status (14)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI3553177T1 (sl) | 2013-03-15 | 2021-03-31 | The Board Of Trustees Of The Leland Stanford Junior University | Mikrobi, ki proizvajajo benzilizokinolinske alkaloide (BIA), in postopka za pripravo in uporabo le-teh |
| EP3066207A1 (en) | 2013-11-04 | 2016-09-14 | The Board Of Trustees Of The University Of the Leland Stanford Junior University | Benzylisoquinoline alkaloid (bia) precursor producing microbes, and methods of making and using the same |
| EP4289959B1 (en) * | 2013-12-04 | 2026-05-13 | Antheia, Inc. | Compositions and methods for making (r)-reticuline and precursors thereof |
| AU2015261278C1 (en) * | 2014-05-16 | 2021-06-03 | Sun Pharmaceutical Industries (Australia) Pty Limited | Novel cytochrome P450 fusion protein |
| WO2016179296A1 (en) | 2015-05-04 | 2016-11-10 | The Board Of Trustees Of The Leland Stanford Junior University | Benzylisoquinoline alkaloid (bia) precursor producing microbes, and methods of making and using the same |
| CA2983445A1 (en) * | 2015-05-08 | 2016-11-17 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of producing epimerases and benzylisoquinoline alkaloids |
| GB201511156D0 (en) * | 2015-06-24 | 2015-08-05 | Glaxosmithkline Australia Pty Ltd And University Of York | Production of alkaloids |
| AU2017289304B2 (en) | 2016-06-27 | 2023-09-28 | Antheia, Inc. | Polynucleotides and polypeptides useful for making alkaloid compounds |
| AU2017290594B2 (en) | 2016-06-27 | 2022-02-17 | Intrexon Corporation | Compositions and methods for making benzylisoquinoline alkaloids, morphinan alkaloids, thebaine, and derivatives thereof |
| CN106119265B (zh) * | 2016-06-30 | 2019-04-30 | 湖南美可达生物资源股份有限公司 | 博落回中参与血根碱与白屈菜红碱合成的细胞色素p450酶基因及其应用 |
| CN110114457A (zh) | 2016-10-18 | 2019-08-09 | 安思雅公司 | 产生去甲阿片类和nal-阿片类苄基异喹啉生物碱的方法 |
| WO2019028390A1 (en) * | 2017-08-03 | 2019-02-07 | Antheia, Inc. | ALKALOID BENZYLISOQUINOLEIN GENETICALLY MODIFIED EPIMERASES AND METHODS FOR PRODUCING BENZYLISOQUINOLINE ALKALOIDS |
| JP7483617B2 (ja) | 2018-02-08 | 2024-05-15 | アンテイア インコーポレイテッド | モルフィナンアルカロイドおよび誘導体を生成する方法 |
| MX2021010797A (es) | 2019-03-08 | 2021-12-10 | Univ Leland Stanford Junior | Células hospederas no vegetales productoras de alcaloides del tropano (ta), y métodos de preparacion y uso de los mismos. |
| JP7648038B2 (ja) | 2019-06-24 | 2025-03-18 | ファーメランタ株式会社 | （ｒ）－レチクリンの生産方法 |
| US20260168000A1 (en) | 2022-11-08 | 2026-06-18 | River Stone Biotech Aps | Genetically modified benzylisoquinoline alkaloid-producing host cells with modified efflux transporter gene expression |
| CN119776567A (zh) * | 2024-12-16 | 2025-04-08 | 广西壮族自治区农业科学院 | 鉴定番荔枝种质资源的分子标记引物试剂盒及应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3785927A (en) | 1973-02-12 | 1974-01-15 | Merck & Co Inc | Process for converting(-)reticuline to(+)salutaridine |
| GB1408729A (en) * | 1973-08-13 | 1975-10-01 | Lilly Co Eli | Sulphilimine compounds |
| US5268463A (en) | 1986-11-11 | 1993-12-07 | Jefferson Richard A | Plant promoter α-glucuronidase gene construct |
| AUPP946399A0 (en) * | 1999-03-26 | 1999-04-22 | Johnson & Johnson Research Pty. Limited | Codeinone reductase from alkaloid poppy |
| US20070298481A1 (en) * | 2003-09-17 | 2007-12-27 | Fumihiko Sato | Method for Producing a Useful Intermediate in Alkaloid Biosynthesis By Using Rnai Technology |
| EP1837396A1 (en) * | 2006-03-23 | 2007-09-26 | Institut für Pflanzenbiochemie-IPB | Salutaridine reductase and morphine biosynthesis |
| WO2008067070A2 (en) * | 2006-10-19 | 2008-06-05 | California Institute Of Technology | Compositions and methods for producing benzylisoquinolines alkaloids |
| WO2011058446A2 (en) | 2009-11-12 | 2011-05-19 | Uti Limited Partnership | Thebaine 6-o-demethylase and codeine o-demethylase from papaver somniferum |
| EP4289959B1 (en) * | 2013-12-04 | 2026-05-13 | Antheia, Inc. | Compositions and methods for making (r)-reticuline and precursors thereof |
| WO2015103711A1 (en) | 2014-01-13 | 2015-07-16 | Valorbec Société en Commandite | Method of making a benzylisoquinoline alkaloid (bia) metabolite, enzymes therefore |
| AU2015261278C1 (en) * | 2014-05-16 | 2021-06-03 | Sun Pharmaceutical Industries (Australia) Pty Limited | Novel cytochrome P450 fusion protein |
| CA2983445A1 (en) | 2015-05-08 | 2016-11-17 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of producing epimerases and benzylisoquinoline alkaloids |
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2014
- 2014-12-03 EP EP23188492.5A patent/EP4289959B1/en active Active
- 2014-12-03 DK DK14867017.7T patent/DK3077513T5/da active
- 2014-12-03 AU AU2014360597A patent/AU2014360597B2/en active Active
- 2014-12-03 DK DK23188492.5T patent/DK4289959T3/da active
- 2014-12-03 RU RU2016124228A patent/RU2729065C2/ru active
- 2014-12-03 EP EP26177647.0A patent/EP4793348A2/en active Pending
- 2014-12-03 KR KR1020167017344A patent/KR102018240B1/ko active Active
- 2014-12-03 EP EP14867017.7A patent/EP3077513B1/en active Active
- 2014-12-03 CN CN202210963307.6A patent/CN115927140A/zh active Pending
- 2014-12-03 MX MX2016007176A patent/MX364825B/es active IP Right Grant
- 2014-12-03 US US15/101,474 patent/US10190141B2/en active Active
- 2014-12-03 KR KR1020197025315A patent/KR102491060B1/ko active Active
- 2014-12-03 ES ES14867017T patent/ES2961516T3/es active Active
- 2014-12-03 BR BR112016012595-9A patent/BR112016012595B1/pt active IP Right Grant
- 2014-12-03 WO PCT/CA2014/051164 patent/WO2015081437A1/en not_active Ceased
- 2014-12-03 JP JP2016536954A patent/JP6783655B2/ja active Active
- 2014-12-03 CA CA2932448A patent/CA2932448C/en active Active
- 2014-12-03 CN CN201480071559.1A patent/CN105980563B/zh active Active
- 2014-12-03 CN CN202210963296.1A patent/CN115927139A/zh active Pending
-
2016
- 2016-06-01 IL IL245970A patent/IL245970B/en active IP Right Grant
-
2018
- 2018-12-07 US US16/213,037 patent/US11613770B2/en active Active
-
2019
- 2019-12-09 IL IL271289A patent/IL271289B/en unknown
-
2020
- 2020-01-08 AU AU2020200131A patent/AU2020200131A1/en not_active Abandoned
- 2020-03-10 AU AU2020201743A patent/AU2020201743B2/en active Active
-
2022
- 2022-11-29 AU AU2022279419A patent/AU2022279419B2/en active Active
-
2023
- 2023-03-06 US US18/179,035 patent/US20240002894A1/en active Pending
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