MX2021010797A - Células hospederas no vegetales productoras de alcaloides del tropano (ta), y métodos de preparacion y uso de los mismos. - Google Patents
Células hospederas no vegetales productoras de alcaloides del tropano (ta), y métodos de preparacion y uso de los mismos.Info
- Publication number
- MX2021010797A MX2021010797A MX2021010797A MX2021010797A MX2021010797A MX 2021010797 A MX2021010797 A MX 2021010797A MX 2021010797 A MX2021010797 A MX 2021010797A MX 2021010797 A MX2021010797 A MX 2021010797A MX 2021010797 A MX2021010797 A MX 2021010797A
- Authority
- MX
- Mexico
- Prior art keywords
- tropane alkaloid
- making
- methods
- same
- host cells
- Prior art date
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- C12Y305/00—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5)
- C12Y305/03—Hydrolases acting on carbon-nitrogen bonds, other than peptide bonds (3.5) in linear amidines (3.5.3)
- C12Y305/03011—Agmatinase (3.5.3.11)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y403/00—Carbon-nitrogen lyases (4.3)
- C12Y403/01—Ammonia-lyases (4.3.1)
- C12Y403/01024—Phenylalanine ammonia-lyase (4.3.1.24)
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Abstract
En la presente, entre otras cosas, se proporciona una célula no vegetal diseñada que produce un producto alcaloide del tropano, un precursor de un producto alcaloide del tropano o un derivado de un producto alcaloide del tropano. También se describe un método para producir un alcaloide del tropano, un precursor de un producto alcaloide del tropano o un derivado de un producto alcaloide del tropano que hace uso de la célula.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
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US201962815709P | 2019-03-08 | 2019-03-08 | |
US201962848419P | 2019-05-15 | 2019-05-15 | |
US201962891771P | 2019-08-26 | 2019-08-26 | |
PCT/US2020/021577 WO2020185626A1 (en) | 2019-03-08 | 2020-03-06 | Tropane alkaloid (ta) producing non-plant host cells, and methods of making and using the same |
Publications (1)
Publication Number | Publication Date |
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MX2021010797A true MX2021010797A (es) | 2021-12-10 |
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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MX2021010797A MX2021010797A (es) | 2019-03-08 | 2020-03-06 | Células hospederas no vegetales productoras de alcaloides del tropano (ta), y métodos de preparacion y uso de los mismos. |
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US (1) | US20220170026A1 (es) |
EP (1) | EP3934765A4 (es) |
JP (1) | JP2022523825A (es) |
KR (1) | KR20210138642A (es) |
CN (1) | CN113784758A (es) |
AU (1) | AU2020234767A1 (es) |
BR (1) | BR112021017659A2 (es) |
CA (1) | CA3132968A1 (es) |
MX (1) | MX2021010797A (es) |
WO (1) | WO2020185626A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
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IL255136B2 (en) | 2015-05-08 | 2023-09-01 | Univ Leland Stanford Junior | Methods for generating epimerases and benzylisoquinoline alkaloids |
CN110452916B (zh) * | 2019-09-03 | 2020-11-10 | 西南大学 | 莨菪醛还原酶及其应用 |
US20240191267A1 (en) * | 2021-03-25 | 2024-06-13 | The Board Of Trustees Of The Leland Stanford Junior University | Tropane Alkaloid Transporters and Methods of Making Tropane Alkaloids Using the Same |
CN113307884B (zh) * | 2021-05-25 | 2022-04-29 | 西南大学 | 托品酮生物合成融合蛋白及其应用和方法 |
CN113308447B (zh) * | 2021-05-31 | 2022-09-30 | 西南大学 | 拟南芥ugt74f2在催化苯乳酸合成苯乳酰葡萄糖中的应用 |
CN116790536B (zh) * | 2022-07-13 | 2024-06-04 | 中国科学院昆明植物研究所 | 来自古柯的芽子酮甲基转移酶EnEMT1和EnEMT2及其基因和应用 |
CN115466255B (zh) * | 2022-11-01 | 2023-03-10 | 北京世纪迈劲生物科技有限公司 | 一种托品醇及其合成方法 |
CN116676355B (zh) * | 2023-08-03 | 2023-10-24 | 成都第一制药有限公司 | 一种催化合成山莨菪碱的方法 |
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Publication number | Priority date | Publication date | Assignee | Title |
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US20070199090A1 (en) * | 2006-02-22 | 2007-08-23 | Nestor Apuya | Modulating alkaloid biosynthesis |
EP2038406A2 (en) * | 2006-06-19 | 2009-03-25 | National Research Council of Canada | Nucleic acid encoding n-methylputrescine oxidase and uses thereof |
US9102948B2 (en) * | 2006-11-17 | 2015-08-11 | 22Nd Century Limited, Llc | Regulating alkaloids |
US11124814B2 (en) * | 2013-11-04 | 2021-09-21 | The Board Of Trustees Of The Leland Stanford Junior University | Benzylisoquinoline alkaloid (BIA) precursor producing microbes, and methods of making and using the same |
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2020
- 2020-03-06 JP JP2021552817A patent/JP2022523825A/ja active Pending
- 2020-03-06 BR BR112021017659A patent/BR112021017659A2/pt unknown
- 2020-03-06 CA CA3132968A patent/CA3132968A1/en active Pending
- 2020-03-06 AU AU2020234767A patent/AU2020234767A1/en active Pending
- 2020-03-06 MX MX2021010797A patent/MX2021010797A/es unknown
- 2020-03-06 EP EP20770558.3A patent/EP3934765A4/en active Pending
- 2020-03-06 KR KR1020217032056A patent/KR20210138642A/ko active Search and Examination
- 2020-03-06 WO PCT/US2020/021577 patent/WO2020185626A1/en active Application Filing
- 2020-03-06 US US17/436,546 patent/US20220170026A1/en active Pending
- 2020-03-06 CN CN202080033469.9A patent/CN113784758A/zh active Pending
Also Published As
Publication number | Publication date |
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US20220170026A1 (en) | 2022-06-02 |
AU2020234767A1 (en) | 2021-10-07 |
CN113784758A (zh) | 2021-12-10 |
EP3934765A4 (en) | 2022-11-30 |
KR20210138642A (ko) | 2021-11-19 |
CA3132968A1 (en) | 2020-09-17 |
BR112021017659A2 (pt) | 2021-11-16 |
JP2022523825A (ja) | 2022-04-26 |
EP3934765A1 (en) | 2022-01-12 |
WO2020185626A1 (en) | 2020-09-17 |
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