JP2017078088A5 - - Google Patents
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- Publication number
- JP2017078088A5 JP2017078088A5 JP2016249134A JP2016249134A JP2017078088A5 JP 2017078088 A5 JP2017078088 A5 JP 2017078088A5 JP 2016249134 A JP2016249134 A JP 2016249134A JP 2016249134 A JP2016249134 A JP 2016249134A JP 2017078088 A5 JP2017078088 A5 JP 2017078088A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- pvp
- dmso
- treating
- dimethyl sulfoxide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims 50
- 239000000203 mixture Substances 0.000 claims 40
- FAAHNQAYWKTLFD-UHFFFAOYSA-N 1-butan-2-ylpyrrolidin-2-one Chemical compound CCC(C)N1CCCC1=O FAAHNQAYWKTLFD-UHFFFAOYSA-N 0.000 claims 12
- CPKVUHPKYQGHMW-UHFFFAOYSA-N 1-ethenylpyrrolidin-2-one;molecular iodine Chemical compound II.C=CN1CCCC1=O CPKVUHPKYQGHMW-UHFFFAOYSA-N 0.000 claims 4
- 208000010195 Onychomycosis Diseases 0.000 claims 3
- 208000015181 infectious disease Diseases 0.000 claims 3
- 201000005882 tinea unguium Diseases 0.000 claims 3
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims 2
- 244000294611 Punica granatum Species 0.000 claims 2
- 235000014360 Punica granatum Nutrition 0.000 claims 2
- 244000269722 Thea sinensis Species 0.000 claims 2
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims 2
- 229940121375 antifungal agent Drugs 0.000 claims 2
- 239000003429 antifungal agent Substances 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- URAYPUMNDPQOKB-UHFFFAOYSA-N triacetin Chemical compound CC(=O)OCC(OC(C)=O)COC(C)=O URAYPUMNDPQOKB-UHFFFAOYSA-N 0.000 claims 2
- XMAYWYJOQHXEEK-OZXSUGGESA-N (2R,4S)-ketoconazole Chemical compound C1CN(C(=O)C)CCN1C(C=C1)=CC=C1OC[C@@H]1O[C@@](CN2C=NC=C2)(C=2C(=CC(Cl)=CC=2)Cl)OC1 XMAYWYJOQHXEEK-OZXSUGGESA-N 0.000 claims 1
- MCCACAIVAXEFAL-UHFFFAOYSA-N 1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole;nitric acid Chemical compound O[N+]([O-])=O.ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 MCCACAIVAXEFAL-UHFFFAOYSA-N 0.000 claims 1
- FRPZMMHWLSIFAZ-UHFFFAOYSA-N 10-undecenoic acid Chemical compound OC(=O)CCCCCCCCC=C FRPZMMHWLSIFAZ-UHFFFAOYSA-N 0.000 claims 1
- MBRHNTMUYWQHMR-UHFFFAOYSA-N 2-aminoethanol;6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one Chemical compound NCCO.ON1C(=O)C=C(C)C=C1C1CCCCC1 MBRHNTMUYWQHMR-UHFFFAOYSA-N 0.000 claims 1
- SODWJACROGQSMM-UHFFFAOYSA-N 5,6,7,8-tetrahydronaphthalen-1-amine Chemical compound C1CCCC2=C1C=CC=C2N SODWJACROGQSMM-UHFFFAOYSA-N 0.000 claims 1
- 241000517645 Abra Species 0.000 claims 1
- POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 claims 1
- 241000238421 Arthropoda Species 0.000 claims 1
- QCDFBFJGMNKBDO-UHFFFAOYSA-N Clioquinol Chemical compound C1=CN=C2C(O)=C(I)C=C(Cl)C2=C1 QCDFBFJGMNKBDO-UHFFFAOYSA-N 0.000 claims 1
- 240000008067 Cucumis sativus Species 0.000 claims 1
- 235000009849 Cucumis sativus Nutrition 0.000 claims 1
- 206010073931 Genital herpes simplex Diseases 0.000 claims 1
- 244000303040 Glycyrrhiza glabra Species 0.000 claims 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims 1
- 208000001688 Herpes Genitalis Diseases 0.000 claims 1
- 206010023330 Keloid scar Diseases 0.000 claims 1
- BYBLEWFAAKGYCD-UHFFFAOYSA-N Miconazole Chemical compound ClC1=CC(Cl)=CC=C1COC(C=1C(=CC(Cl)=CC=1)Cl)CN1C=NC=C1 BYBLEWFAAKGYCD-UHFFFAOYSA-N 0.000 claims 1
- 206010065764 Mucosal infection Diseases 0.000 claims 1
- 229910002651 NO3 Inorganic materials 0.000 claims 1
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 claims 1
- 241000700584 Simplexvirus Species 0.000 claims 1
- 235000006468 Thea sinensis Nutrition 0.000 claims 1
- 229960000458 allantoin Drugs 0.000 claims 1
- 235000010323 ascorbic acid Nutrition 0.000 claims 1
- 229960005070 ascorbic acid Drugs 0.000 claims 1
- 239000011668 ascorbic acid Substances 0.000 claims 1
- 229940002386 calendula officinalis extract Drugs 0.000 claims 1
- KHAVLLBUVKBTBG-UHFFFAOYSA-N caproleic acid Natural products OC(=O)CCCCCCCC=C KHAVLLBUVKBTBG-UHFFFAOYSA-N 0.000 claims 1
- 229960004375 ciclopirox olamine Drugs 0.000 claims 1
- 210000000078 claw Anatomy 0.000 claims 1
- 229960005228 clioquinol Drugs 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 229960003645 econazole nitrate Drugs 0.000 claims 1
- 235000013399 edible fruits Nutrition 0.000 claims 1
- XRECTZIEBJDKEO-UHFFFAOYSA-N flucytosine Chemical compound NC1=NC(=O)NC=C1F XRECTZIEBJDKEO-UHFFFAOYSA-N 0.000 claims 1
- 229960004413 flucytosine Drugs 0.000 claims 1
- 201000004946 genital herpes Diseases 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 235000013773 glyceryl triacetate Nutrition 0.000 claims 1
- 239000001087 glyceryl triacetate Substances 0.000 claims 1
- 239000011497 hempcrete Substances 0.000 claims 1
- 230000001969 hypertrophic effect Effects 0.000 claims 1
- 230000002458 infectious effect Effects 0.000 claims 1
- 230000003601 intercostal effect Effects 0.000 claims 1
- 229960004125 ketoconazole Drugs 0.000 claims 1
- 201000011486 lichen planus Diseases 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 229960002509 miconazole Drugs 0.000 claims 1
- 229960005040 miconazole nitrate Drugs 0.000 claims 1
- 208000026721 nail disease Diseases 0.000 claims 1
- 229960000988 nystatin Drugs 0.000 claims 1
- VQOXZBDYSJBXMA-NQTDYLQESA-N nystatin A1 Chemical compound O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/CC/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 VQOXZBDYSJBXMA-NQTDYLQESA-N 0.000 claims 1
- 206010034674 peritonitis Diseases 0.000 claims 1
- 239000012466 permeate Substances 0.000 claims 1
- 229920000151 polyglycol Polymers 0.000 claims 1
- 239000010695 polyglycol Substances 0.000 claims 1
- 230000002980 postoperative effect Effects 0.000 claims 1
- 230000001185 psoriatic effect Effects 0.000 claims 1
- 238000002271 resection Methods 0.000 claims 1
- 231100000241 scar Toxicity 0.000 claims 1
- DOMXUEMWDBAQBQ-WEVVVXLNSA-N terbinafine Chemical compound C1=CC=C2C(CN(C\C=C\C#CC(C)(C)C)C)=CC=CC2=C1 DOMXUEMWDBAQBQ-WEVVVXLNSA-N 0.000 claims 1
- 229960002722 terbinafine Drugs 0.000 claims 1
- 201000004647 tinea pedis Diseases 0.000 claims 1
- FUSNMLFNXJSCDI-UHFFFAOYSA-N tolnaftate Chemical compound C=1C=C2C=CC=CC2=CC=1OC(=S)N(C)C1=CC=CC(C)=C1 FUSNMLFNXJSCDI-UHFFFAOYSA-N 0.000 claims 1
- 229960004880 tolnaftate Drugs 0.000 claims 1
- 229960002622 triacetin Drugs 0.000 claims 1
- 229960002703 undecylenic acid Drugs 0.000 claims 1
- 230000009385 viral infection Effects 0.000 claims 1
Applications Claiming Priority (12)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161518690P | 2011-05-11 | 2011-05-11 | |
| US201161518709P | 2011-05-11 | 2011-05-11 | |
| US201161518689P | 2011-05-11 | 2011-05-11 | |
| US61/518,690 | 2011-05-11 | ||
| US61/518,709 | 2011-05-11 | ||
| US61/518,689 | 2011-05-11 | ||
| US201161457699P | 2011-05-16 | 2011-05-16 | |
| US61/457,699 | 2011-05-16 | ||
| US201161627148P | 2011-09-19 | 2011-09-19 | |
| US61/627,148 | 2011-09-19 | ||
| US201261600268P | 2012-02-17 | 2012-02-17 | |
| US61/600,268 | 2012-02-17 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510408A Division JP6077527B2 (ja) | 2011-05-11 | 2012-05-08 | 皮膚および爪の治療のための抗真菌組成物 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017142731A Division JP6239183B1 (ja) | 2011-05-11 | 2017-07-24 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2017196917A Division JP6273065B1 (ja) | 2011-05-11 | 2017-10-10 | 皮膚および爪の治療のための抗真菌組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017078088A JP2017078088A (ja) | 2017-04-27 |
| JP2017078088A5 true JP2017078088A5 (enExample) | 2017-09-07 |
| JP6236141B2 JP6236141B2 (ja) | 2017-11-22 |
Family
ID=47139601
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510408A Expired - Fee Related JP6077527B2 (ja) | 2011-05-11 | 2012-05-08 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2016249134A Expired - Fee Related JP6236141B2 (ja) | 2011-05-11 | 2016-12-22 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2017142731A Expired - Fee Related JP6239183B1 (ja) | 2011-05-11 | 2017-07-24 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2017196917A Expired - Fee Related JP6273065B1 (ja) | 2011-05-11 | 2017-10-10 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2017239488A Expired - Fee Related JP6307203B1 (ja) | 2011-05-11 | 2017-12-14 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2018030933A Expired - Fee Related JP6360267B2 (ja) | 2011-05-11 | 2018-02-23 | 皮膚および爪の治療のための抗真菌組成物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014510408A Expired - Fee Related JP6077527B2 (ja) | 2011-05-11 | 2012-05-08 | 皮膚および爪の治療のための抗真菌組成物 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017142731A Expired - Fee Related JP6239183B1 (ja) | 2011-05-11 | 2017-07-24 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2017196917A Expired - Fee Related JP6273065B1 (ja) | 2011-05-11 | 2017-10-10 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2017239488A Expired - Fee Related JP6307203B1 (ja) | 2011-05-11 | 2017-12-14 | 皮膚および爪の治療のための抗真菌組成物 |
| JP2018030933A Expired - Fee Related JP6360267B2 (ja) | 2011-05-11 | 2018-02-23 | 皮膚および爪の治療のための抗真菌組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9408867B2 (enExample) |
| EP (2) | EP2707007B1 (enExample) |
| JP (6) | JP6077527B2 (enExample) |
| CA (1) | CA2835684C (enExample) |
| ES (2) | ES2817835T3 (enExample) |
| MX (1) | MX345458B (enExample) |
| WO (1) | WO2012154740A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2707007B1 (en) | 2011-05-11 | 2018-03-07 | Veloce BioPharma LLC | Antifungal compositions for the treatment of nails |
| CA2864910C (en) * | 2012-02-17 | 2018-07-24 | Joseph CAPRIOTTI | Antifungal compositions for the treatment of skin and nails |
| US20140271529A1 (en) * | 2013-03-14 | 2014-09-18 | Alc Therapeutics, Llc | Antifungal compositions for the treatment of secondary skin and nail infections |
| KR20180011883A (ko) | 2015-01-20 | 2018-02-02 | 벨로체 바이오파르마 엘엘씨 | 신규한 요오드포 조성물 및 사용 방법 |
| EP3258908A4 (en) * | 2015-02-20 | 2018-08-22 | Pedicis Research LLC | Compositions and methods for treatment of skin infections |
| CA2990627A1 (en) | 2015-06-22 | 2016-12-29 | Infection Containment Company, LLC | Topical antiseptic system |
| US20180200289A1 (en) * | 2015-07-02 | 2018-07-19 | Veloce Biopharma, Llc | Novel ophthalmic composition and methods of use |
| US9770466B2 (en) | 2015-07-02 | 2017-09-26 | Veloce Biopharma, Llc | Ophthalmic composition and methods of use |
| JP6255134B1 (ja) * | 2016-11-02 | 2017-12-27 | ヴェローチェ・バイオファーマ・エルエルシー | 耳炎の治療のための組成物および方法 |
| US10993890B2 (en) * | 2018-03-15 | 2021-05-04 | Pelli Skin Co., Llc | Antifungal solution and foot wipe |
Family Cites Families (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE615889A (enExample) * | 1952-04-15 | 1900-01-01 | ||
| US3551554A (en) * | 1968-08-16 | 1970-12-29 | Crown Zellerbach Corp | Enhancing tissue penetration of physiologically active agents with dmso |
| AU4292585A (en) * | 1984-04-30 | 1985-11-28 | Trustees Of Columbia University In The City Of New York, The | Topical treatment of diabetes with insulin and penetrant enhancer applied to the skin and covered by a patch |
| CA1236029A (en) | 1984-05-14 | 1988-05-03 | Edmund Sandborn | Pharmaceutical solutions comprising dimethyl sulfoxide |
| EP0185490B1 (en) * | 1984-12-12 | 1991-09-25 | Euroceltique S.A. | Antibacterial cream |
| JPS6216419A (ja) * | 1985-07-15 | 1987-01-24 | Hirokazu Takaoka | 水虫外用薬 |
| GB2275191B (en) | 1993-02-10 | 1996-11-27 | Donald John Dear | Use of antifungal compounds in the treatment of skin disorders |
| GB9426088D0 (en) * | 1994-12-23 | 1995-02-22 | Geco As | Data compression for uncorrelated vibroseis traces |
| US5993790A (en) * | 1997-08-04 | 1999-11-30 | Pedinol Pharmacal Inc. | Nail evulsion compositions and method for evulsing nails and treating nail and nail bed infections |
| US6264927B1 (en) * | 1998-08-27 | 2001-07-24 | Elmer P. Monahan | Topical solution and method for the treatment of nail fungus |
| US6159977A (en) * | 1998-11-16 | 2000-12-12 | Astan, Inc. | Therapeutic anti-fungal nail preparation |
| US7074392B1 (en) * | 2000-03-27 | 2006-07-11 | Taro Pharmaceutical Industries Limited | Controllled delivery system of antifungal and keratolytic agents for local treatment of fungal infections |
| US20030049320A1 (en) * | 2000-12-18 | 2003-03-13 | Wockhardt Limited | Novel in-situ forming controlled release microcarrier delivery system |
| US6921529B2 (en) * | 2002-07-29 | 2005-07-26 | Joseph C. Maley | Treatment modality and method for fungal nail infection |
| US20070292359A1 (en) * | 2002-10-25 | 2007-12-20 | Foamix Ltd. | Polypropylene glycol foamable vehicle and pharmaceutical compositions thereof |
| US20070292355A1 (en) * | 2002-10-25 | 2007-12-20 | Foamix Ltd. | Anti-infection augmentation foamable compositions and kit and uses thereof |
| EP1635770B1 (en) * | 2003-03-21 | 2009-05-27 | Nexmed Holdings, Inc. | Antifungal nail coat and method of use |
| PT1479379E (pt) * | 2003-05-19 | 2007-10-23 | Euro Celtique Sa | ''composições lipossomais secas de pvp-iodo'' |
| US20040241114A1 (en) * | 2003-05-30 | 2004-12-02 | Gupta Shyam K. | Hair Care and Nail Care Compositions Based on Ion-Pair Delivery System for Gender and Ethnic Selective Applications |
| JP2005097279A (ja) * | 2003-08-28 | 2005-04-14 | Jcs:Kk | 外耳炎治療剤及び外耳道洗浄液 |
| US20060165747A1 (en) | 2005-01-24 | 2006-07-27 | David Rolf | Antifungal composition, method and kit for topically treating onychomycosis |
| GB0511499D0 (en) * | 2005-06-06 | 2005-07-13 | Medpharm Ltd | Topical ungual formulations |
| WO2006135854A2 (en) * | 2005-06-10 | 2006-12-21 | Board Of Regents, The University Of Texas System | Antiseptic compositions |
| CA2617934A1 (en) * | 2005-08-05 | 2007-02-15 | Nuvo Research Inc. | Transdermal drug delivery formulation |
| KR20090029139A (ko) * | 2007-09-17 | 2009-03-20 | 김부례 | 연화와 침투, 흡수작용의 발무좀 발톱무좀 치료 연고 |
| CN100531706C (zh) * | 2007-10-29 | 2009-08-26 | 广东庆发药业有限公司 | 抗菌消毒洗手液及其制备方法 |
| US20090263345A1 (en) * | 2008-01-28 | 2009-10-22 | Foresight Biotherapeutics, Inc. | Otic compositions for the treatment of infections of the internal and external ear in mammals |
| CN101693038B (zh) * | 2008-10-17 | 2012-06-20 | 吴霜 | 一种治疗皮肤(甲)病的药物组合物 |
| EP2707007B1 (en) | 2011-05-11 | 2018-03-07 | Veloce BioPharma LLC | Antifungal compositions for the treatment of nails |
| US20140271529A1 (en) * | 2013-03-14 | 2014-09-18 | Alc Therapeutics, Llc | Antifungal compositions for the treatment of secondary skin and nail infections |
-
2012
- 2012-05-08 EP EP12781719.5A patent/EP2707007B1/en not_active Not-in-force
- 2012-05-08 CA CA2835684A patent/CA2835684C/en active Active
- 2012-05-08 EP EP18153685.5A patent/EP3348272B1/en not_active Not-in-force
- 2012-05-08 ES ES18153685T patent/ES2817835T3/es active Active
- 2012-05-08 MX MX2013013082A patent/MX345458B/es active IP Right Grant
- 2012-05-08 JP JP2014510408A patent/JP6077527B2/ja not_active Expired - Fee Related
- 2012-05-08 WO PCT/US2012/036942 patent/WO2012154740A1/en not_active Ceased
- 2012-05-08 ES ES12781719.5T patent/ES2665986T3/es active Active
- 2012-05-08 US US14/116,360 patent/US9408867B2/en not_active Expired - Fee Related
-
2016
- 2016-07-18 US US15/213,289 patent/US20170000820A1/en not_active Abandoned
- 2016-12-22 JP JP2016249134A patent/JP6236141B2/ja not_active Expired - Fee Related
-
2017
- 2017-07-24 JP JP2017142731A patent/JP6239183B1/ja not_active Expired - Fee Related
- 2017-10-10 JP JP2017196917A patent/JP6273065B1/ja not_active Expired - Fee Related
- 2017-12-14 JP JP2017239488A patent/JP6307203B1/ja not_active Expired - Fee Related
-
2018
- 2018-02-23 JP JP2018030933A patent/JP6360267B2/ja not_active Expired - Fee Related
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