JP2017066164A5 - - Google Patents
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- Publication number
- JP2017066164A5 JP2017066164A5 JP2017004062A JP2017004062A JP2017066164A5 JP 2017066164 A5 JP2017066164 A5 JP 2017066164A5 JP 2017004062 A JP2017004062 A JP 2017004062A JP 2017004062 A JP2017004062 A JP 2017004062A JP 2017066164 A5 JP2017066164 A5 JP 2017066164A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- alkyl
- cycloalkyl
- divalent
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161558080P | 2011-11-10 | 2011-11-10 | |
| US61/558,080 | 2011-11-10 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541358A Division JP6078075B2 (ja) | 2011-11-10 | 2012-11-10 | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体調節因子としての２，５−ジオキソイミダゾリジン−１−イル−３−フェニル尿素誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017066164A JP2017066164A (ja) | 2017-04-06 |
| JP2017066164A5 true JP2017066164A5 (https=) | 2018-03-15 |
| JP6392382B2 JP6392382B2 (ja) | 2018-09-19 |
Family
ID=47222328
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541358A Expired - Fee Related JP6078075B2 (ja) | 2011-11-10 | 2012-11-10 | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体調節因子としての２，５−ジオキソイミダゾリジン−１−イル−３−フェニル尿素誘導体 |
| JP2017004062A Expired - Fee Related JP6392382B2 (ja) | 2011-11-10 | 2017-01-13 | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体調節因子としての２，５−ジオキソイミダゾリジン−１−イル−３−フェニル尿素誘導体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541358A Expired - Fee Related JP6078075B2 (ja) | 2011-11-10 | 2012-11-10 | ホルミルペプチド受容体様１（ｆｐｒｌ−１）受容体調節因子としての２，５−ジオキソイミダゾリジン−１−イル−３−フェニル尿素誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US8492556B2 (https=) |
| EP (2) | EP3103797B1 (https=) |
| JP (2) | JP6078075B2 (https=) |
| KR (1) | KR102271500B1 (https=) |
| CN (1) | CN104114541A (https=) |
| AU (2) | AU2012335039C1 (https=) |
| BR (1) | BR112014011316A2 (https=) |
| CA (1) | CA2855390C (https=) |
| DK (1) | DK3103797T3 (https=) |
| ES (1) | ES2733826T3 (https=) |
| RU (1) | RU2645673C2 (https=) |
| TR (1) | TR201909663T4 (https=) |
| WO (1) | WO2013071203A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106518742B (zh) | 2011-10-26 | 2020-01-21 | 阿勒根公司 | 作为甲酰肽受体样-1(fprl-1)受体调节剂的n-脲取代的氨基酸的酰胺衍生物 |
| US8492556B2 (en) * | 2011-11-10 | 2013-07-23 | Allergan, Inc. | 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators |
| BR122017004254B1 (pt) * | 2013-03-06 | 2021-04-13 | Allergan, Inc. | Uso de agonistas de receptor de formil peptídeo 2 para tratar doenças inflamatórias oculares |
| BR112015021392B1 (pt) | 2013-03-06 | 2021-11-16 | Allergan, Inc | Uso de agonistas do receptor de peptídeo formil 2 para tratar doenças dermatológicas |
| AR097279A1 (es) * | 2013-08-09 | 2016-03-02 | Actelion Pharmaceuticals Ltd | Derivados de benzimidazolil-metil urea como agonistas del receptor de alx |
| RU2703725C1 (ru) | 2013-11-21 | 2019-10-22 | Аллерган, Инк. | Производные фенилкарбамата в качестве модуляторов формилпептидного рецептора |
| ES2752733T3 (es) | 2013-11-28 | 2020-04-06 | Kyorin Seiyaku Kk | Derivados de urea deuterados o marcados isotópicamente o sales farmacológicamente aceptables de los mismos útiles como agonistas de FPRL-1 |
| WO2015116574A1 (en) * | 2014-01-29 | 2015-08-06 | Allergan, Inc. | Urea hydantoin derivatives as formyl peptide modulators |
| WO2015116566A1 (en) | 2014-01-29 | 2015-08-06 | Allergan, Inc. | 2,5-dioxoimidazolidin-1-yl-3-urea derivatives as formyl peptide modulators |
| CA2948876A1 (en) * | 2014-05-21 | 2015-11-26 | Allergan, Inc. | Imidazole derivatives as formyl peptide receptor modulators |
| SG11201704764PA (en) | 2014-12-11 | 2017-07-28 | Harvard College | Inhibitors of cellular necrosis and related methods |
| JP6746613B2 (ja) | 2015-05-27 | 2020-08-26 | 杏林製薬株式会社 | ウレア誘導体、またはその薬理学的に許容される塩 |
| JP6746614B2 (ja) | 2015-05-27 | 2020-08-26 | 杏林製薬株式会社 | ウレア誘導体、またはその薬理学的に許容される塩 |
| JP2020015664A (ja) * | 2016-11-21 | 2020-01-30 | 宇部興産株式会社 | 含窒素多環式ヘテロ環誘導体 |
| WO2018227067A1 (en) * | 2017-06-09 | 2018-12-13 | Bristol-Myers Squibb Company | Cyclopropyl urea formyl peptide 2 receptor and formyl peptide 1 receptor agonists |
| US10676431B2 (en) | 2018-03-05 | 2020-06-09 | Bristol-Myers Squibb Company | Phenylpyrrolidinone formyl peptide 2 receptor agonists |
| KR102217512B1 (ko) * | 2020-07-07 | 2021-02-19 | 한화시스템 주식회사 | 배터리 관리 시스템을 통한 회수 요청 또는 자동 복귀를 수행하는 무인 잠수정 |
| CN114805334B (zh) * | 2022-05-24 | 2023-06-09 | 深圳大学 | 一种QC和GSK-3β多靶向抑制剂及其制备方法与应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL152961A0 (en) * | 2000-05-31 | 2003-06-24 | Tanabe Seiyaku Co | Inhibitors of alpha beta 2 mediated cell adhesion |
| SE0100903D0 (sv) * | 2001-03-15 | 2001-03-15 | Astrazeneca Ab | Compounds |
| WO2003006424A1 (en) * | 2001-07-10 | 2003-01-23 | 4Sc Ag | Novel compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents |
| FR2850652B1 (fr) * | 2003-01-31 | 2008-05-30 | Aventis Pharma Sa | Nouveaux derives d'uree cyclique, leur preparation et leur utilisation pharmaceutique comme inhibiteurs de kinases |
| CN1894580A (zh) * | 2003-11-07 | 2007-01-10 | 阿卡蒂亚药品公司 | 脂氧素受体fprl1作为一种用于鉴定能有效治疗疼痛和炎症化合物的工具 |
| WO2005087236A1 (en) * | 2004-03-11 | 2005-09-22 | Glaxo Group Limited | Novel m3 muscarinic acetylcholine receptor antagonists |
| CN100506802C (zh) * | 2004-06-04 | 2009-07-01 | 中国科学院上海药物研究所 | 一类甲酰肽样受体-1调节剂、其制备方法和用途 |
| CA2652307A1 (en) * | 2006-04-10 | 2007-10-18 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| WO2009064431A1 (en) * | 2007-11-15 | 2009-05-22 | Eisai E & D Management Co., Ltd. | Methods of use |
| US8492556B2 (en) * | 2011-11-10 | 2013-07-23 | Allergan, Inc. | 2,5-Dioxoimidazolidin-1-yl-3-phenylurea derivatives as formyl peptide receptor like-1 (FPRL-1) receptor modulators |
| US8541577B2 (en) * | 2011-11-10 | 2013-09-24 | Allergan, Inc. | Aryl urea derivatives as N-formyl peptide receptors like-1 (FPRL-1) receptor modulators |
| CA2864893A1 (en) * | 2012-02-16 | 2013-08-22 | Allergan, Inc. | Imidazolidine-2,4-dione derivatives as n-formyl peptide receptor 2 modulators |
-
2012
- 2012-11-09 US US13/673,800 patent/US8492556B2/en active Active
- 2012-11-10 WO PCT/US2012/064571 patent/WO2013071203A1/en not_active Ceased
- 2012-11-10 ES ES16177209T patent/ES2733826T3/es active Active
- 2012-11-10 AU AU2012335039A patent/AU2012335039C1/en not_active Ceased
- 2012-11-10 RU RU2014122753A patent/RU2645673C2/ru active
- 2012-11-10 BR BR112014011316A patent/BR112014011316A2/pt not_active Application Discontinuation
- 2012-11-10 EP EP16177209.0A patent/EP3103797B1/en active Active
- 2012-11-10 KR KR1020147015539A patent/KR102271500B1/ko not_active Expired - Fee Related
- 2012-11-10 CN CN201280060036.8A patent/CN104114541A/zh active Pending
- 2012-11-10 TR TR2019/09663T patent/TR201909663T4/tr unknown
- 2012-11-10 EP EP12791050.3A patent/EP2776403B1/en not_active Not-in-force
- 2012-11-10 JP JP2014541358A patent/JP6078075B2/ja not_active Expired - Fee Related
- 2012-11-10 CA CA2855390A patent/CA2855390C/en active Active
- 2012-11-10 DK DK16177209.0T patent/DK3103797T3/da active
-
2017
- 2017-01-13 JP JP2017004062A patent/JP6392382B2/ja not_active Expired - Fee Related
- 2017-11-16 AU AU2017261559A patent/AU2017261559C1/en not_active Ceased
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