JP2017061467A5 - - Google Patents
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- JP2017061467A5 JP2017061467A5 JP2016202169A JP2016202169A JP2017061467A5 JP 2017061467 A5 JP2017061467 A5 JP 2017061467A5 JP 2016202169 A JP2016202169 A JP 2016202169A JP 2016202169 A JP2016202169 A JP 2016202169A JP 2017061467 A5 JP2017061467 A5 JP 2017061467A5
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- 239000000203 mixture Substances 0.000 claims 16
- 238000009472 formulation Methods 0.000 claims 15
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 7
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 7
- 239000005557 antagonist Substances 0.000 claims 7
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 239000000825 pharmaceutical preparation Substances 0.000 claims 5
- 238000001356 surgical procedure Methods 0.000 claims 5
- 206010064930 age-related macular degeneration Diseases 0.000 claims 4
- 238000002347 injection Methods 0.000 claims 4
- 239000007924 injection Substances 0.000 claims 4
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 3
- 150000001413 amino acids Chemical class 0.000 claims 3
- 239000003937 drug carrier Substances 0.000 claims 3
- 230000007717 exclusion Effects 0.000 claims 3
- 208000030533 eye disease Diseases 0.000 claims 3
- 230000003902 lesion Effects 0.000 claims 3
- 231100000241 scar Toxicity 0.000 claims 3
- 208000002177 Cataract Diseases 0.000 claims 2
- 208000032544 Cicatrix Diseases 0.000 claims 2
- 206010012688 Diabetic retinal oedema Diseases 0.000 claims 2
- 206010012689 Diabetic retinopathy Diseases 0.000 claims 2
- 206010016654 Fibrosis Diseases 0.000 claims 2
- 206010020751 Hypersensitivity Diseases 0.000 claims 2
- 206010038848 Retinal detachment Diseases 0.000 claims 2
- 108091008605 VEGF receptors Proteins 0.000 claims 2
- 102000009484 Vascular Endothelial Growth Factor Receptors Human genes 0.000 claims 2
- 230000007815 allergy Effects 0.000 claims 2
- JNDMLEXHDPKVFC-UHFFFAOYSA-N aluminum;oxygen(2-);yttrium(3+) Chemical compound [O-2].[O-2].[O-2].[Al+3].[Y+3] JNDMLEXHDPKVFC-UHFFFAOYSA-N 0.000 claims 2
- 230000002491 angiogenic effect Effects 0.000 claims 2
- 201000011190 diabetic macular edema Diseases 0.000 claims 2
- 235000015872 dietary supplement Nutrition 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 230000004761 fibrosis Effects 0.000 claims 2
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- 208000002780 macular degeneration Diseases 0.000 claims 2
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- 230000004264 retinal detachment Effects 0.000 claims 2
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- 239000011782 vitamin Substances 0.000 claims 2
- 229940088594 vitamin Drugs 0.000 claims 2
- 229930003231 vitamin Natural products 0.000 claims 2
- 235000013343 vitamin Nutrition 0.000 claims 2
- 229910019901 yttrium aluminum garnet Inorganic materials 0.000 claims 2
- 206010003694 Atrophy Diseases 0.000 claims 1
- 206010055665 Corneal neovascularisation Diseases 0.000 claims 1
- 208000010412 Glaucoma Diseases 0.000 claims 1
- 208000032843 Hemorrhage Diseases 0.000 claims 1
- 208000003923 Hereditary Corneal Dystrophies Diseases 0.000 claims 1
- 241000228402 Histoplasma Species 0.000 claims 1
- 101000851018 Homo sapiens Vascular endothelial growth factor receptor 1 Proteins 0.000 claims 1
- 101000851007 Homo sapiens Vascular endothelial growth factor receptor 2 Proteins 0.000 claims 1
- 206010025421 Macule Diseases 0.000 claims 1
- 208000010164 Multifocal Choroiditis Diseases 0.000 claims 1
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 1
- 229920000153 Povidone-iodine Polymers 0.000 claims 1
- 208000037111 Retinal Hemorrhage Diseases 0.000 claims 1
- 208000002367 Retinal Perforations Diseases 0.000 claims 1
- 208000007014 Retinitis pigmentosa Diseases 0.000 claims 1
- 206010039705 Scleritis Diseases 0.000 claims 1
- 206010046851 Uveitis Diseases 0.000 claims 1
- 102100033178 Vascular endothelial growth factor receptor 1 Human genes 0.000 claims 1
- 102100033177 Vascular endothelial growth factor receptor 2 Human genes 0.000 claims 1
- 208000034698 Vitreous haemorrhage Diseases 0.000 claims 1
- 230000033115 angiogenesis Effects 0.000 claims 1
- 238000002583 angiography Methods 0.000 claims 1
- 230000001384 anti-glaucoma Effects 0.000 claims 1
- 230000037444 atrophy Effects 0.000 claims 1
- 230000004323 axial length Effects 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 201000005667 central retinal vein occlusion Diseases 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 210000003161 choroid Anatomy 0.000 claims 1
- 238000002648 combination therapy Methods 0.000 claims 1
- 206010011005 corneal dystrophy Diseases 0.000 claims 1
- 201000000159 corneal neovascularization Diseases 0.000 claims 1
- 230000004340 degenerative myopia Effects 0.000 claims 1
- 208000001309 degenerative myopia Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 206010014801 endophthalmitis Diseases 0.000 claims 1
- 238000011156 evaluation Methods 0.000 claims 1
- 210000000744 eyelid Anatomy 0.000 claims 1
- 230000004438 eyesight Effects 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 230000004377 improving vision Effects 0.000 claims 1
- 230000004410 intraocular pressure Effects 0.000 claims 1
- 229940076783 lucentis Drugs 0.000 claims 1
- 208000029233 macular holes Diseases 0.000 claims 1
- 230000007102 metabolic function Effects 0.000 claims 1
- 238000000034 method Methods 0.000 claims 1
- 239000002547 new drug Substances 0.000 claims 1
- 150000007523 nucleic acids Chemical group 0.000 claims 1
- 229960001621 povidone-iodine Drugs 0.000 claims 1
- 238000001959 radiotherapy Methods 0.000 claims 1
- 229960003876 ranibizumab Drugs 0.000 claims 1
- 210000001525 retina Anatomy 0.000 claims 1
- 210000003583 retinal pigment epithelium Anatomy 0.000 claims 1
- 208000004644 retinal vein occlusion Diseases 0.000 claims 1
- 238000010561 standard procedure Methods 0.000 claims 1
- 150000003431 steroids Chemical class 0.000 claims 1
- 238000011477 surgical intervention Methods 0.000 claims 1
- 208000011580 syndromic disease Diseases 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000002054 transplantation Methods 0.000 claims 1
- 208000019553 vascular disease Diseases 0.000 claims 1
- 230000004304 visual acuity Effects 0.000 claims 1
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161432245P | 2011-01-13 | 2011-01-13 | |
| US61/432,245 | 2011-01-13 | ||
| US201161434836P | 2011-01-21 | 2011-01-21 | |
| US61/434,836 | 2011-01-21 | ||
| US201161561957P | 2011-11-21 | 2011-11-21 | |
| US61/561,957 | 2011-11-21 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013549502A Division JP2014503555A (ja) | 2011-01-13 | 2012-01-11 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019104939A Division JP2019167366A (ja) | 2011-01-13 | 2019-06-05 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2017061467A JP2017061467A (ja) | 2017-03-30 |
| JP2017061467A5 true JP2017061467A5 (OSRAM) | 2017-05-18 |
Family
ID=45507924
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013549502A Withdrawn JP2014503555A (ja) | 2011-01-13 | 2012-01-11 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2016202169A Pending JP2017061467A (ja) | 2011-01-13 | 2016-10-14 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2019104939A Pending JP2019167366A (ja) | 2011-01-13 | 2019-06-05 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2021146749A Pending JP2021193115A (ja) | 2011-01-13 | 2021-09-09 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2023174006A Active JP7733706B2 (ja) | 2011-01-13 | 2023-10-06 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2025136675A Pending JP2025169389A (ja) | 2011-01-13 | 2025-08-20 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013549502A Withdrawn JP2014503555A (ja) | 2011-01-13 | 2012-01-11 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019104939A Pending JP2019167366A (ja) | 2011-01-13 | 2019-06-05 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2021146749A Pending JP2021193115A (ja) | 2011-01-13 | 2021-09-09 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2023174006A Active JP7733706B2 (ja) | 2011-01-13 | 2023-10-06 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
| JP2025136675A Pending JP2025169389A (ja) | 2011-01-13 | 2025-08-20 | 血管新生眼疾患を処置するためのｖｅｇｆアンタゴニストの使用 |
Country Status (13)
| Country | Link |
|---|---|
| US (14) | US9254338B2 (OSRAM) |
| EP (4) | EP2663325A1 (OSRAM) |
| JP (6) | JP2014503555A (OSRAM) |
| KR (7) | KR20210030510A (OSRAM) |
| CN (1) | CN103533950A (OSRAM) |
| AU (5) | AU2012205599B2 (OSRAM) |
| BR (1) | BR112013017752A8 (OSRAM) |
| CA (1) | CA2824422A1 (OSRAM) |
| HK (1) | HK1244693A1 (OSRAM) |
| IL (3) | IL295359A (OSRAM) |
| MX (3) | MX385629B (OSRAM) |
| SG (4) | SG191334A1 (OSRAM) |
| WO (1) | WO2012097019A1 (OSRAM) |
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| ES2643469T3 (es) | 2006-04-07 | 2017-11-23 | Aerpio Therapeutics, Inc. | Anticuerpos que se unen a la proteína tirosina fosfatasa beta humana (HPTP-beta) y usos de los mismos |
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| US20130095065A1 (en) | 2011-10-13 | 2013-04-18 | Aerpio Therapeutics, Inc. | Methods for Treating Vascular Leak Syndrome and Cancer |
| JO3405B1 (ar) | 2013-01-09 | 2019-10-20 | Regeneron Pharma | الأجسام المضادة لمضاد مستقبل عامل النمو المشتق من الصفائح الدموية - بيتا واستخداماتها |
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| US20170326106A1 (en) * | 2014-12-11 | 2017-11-16 | Bayer Healthcare Llc | Treatment of age related macular degeneration with a small active choroidal neovascularization lesion |
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| JP2023525034A (ja) | 2020-05-08 | 2023-06-14 | リジェネロン・ファーマシューティカルズ・インコーポレイテッド | Ｖｅｇｆトラップおよびミニトラップならびに眼障害およびがんの治療方法 |
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