MX349901B - Uso de un antagonista de factor de crecimiento endotelial vascular para tratar transtornos oculares angiogenicos. - Google Patents

Uso de un antagonista de factor de crecimiento endotelial vascular para tratar transtornos oculares angiogenicos.

Info

Publication number
MX349901B
MX349901B MX2013007847A MX2013007847A MX349901B MX 349901 B MX349901 B MX 349901B MX 2013007847 A MX2013007847 A MX 2013007847A MX 2013007847 A MX2013007847 A MX 2013007847A MX 349901 B MX349901 B MX 349901B
Authority
MX
Mexico
Prior art keywords
vegf antagonist
eye disorders
angiogenic eye
present
methods
Prior art date
Application number
MX2013007847A
Other languages
English (en)
Other versions
MX2013007847A (es
Inventor
D Yancopoulos George
Original Assignee
Regeneron Pharma
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45507924&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX349901(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Regeneron Pharma filed Critical Regeneron Pharma
Publication of MX2013007847A publication Critical patent/MX2013007847A/es
Publication of MX349901B publication Critical patent/MX349901B/es

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La presente invención se refiere a métodos para tratar trastornos oculares angiogénicos al administrar secuencialmente dosis múltiples de un antagonista de VEGF a un paciente. Los métodos de la presente invención incluyen la administración de dosis múltiples de un antagonista de VEGF a un paciente a una frecuencia de una vez cada 8 o más semanas. Los métodos de la presente invención son útiles para el tratamiento de trastornos oculares angiogénicos tales como degeneración macular relacionada con la edad, retinopatía diabética, edema macular diabético, oclusión de vena retiniana central y neovascularización corneal.
MX2013007847A 2011-01-13 2012-01-11 Uso de un antagonista de factor de crecimiento endotelial vascular para tratar transtornos oculares angiogenicos. MX349901B (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201161432245P 2011-01-13 2011-01-13
US201161434836P 2011-01-21 2011-01-21
US201161561957P 2011-11-21 2011-11-21
PCT/US2012/020855 WO2012097019A1 (en) 2011-01-13 2012-01-11 Use of a vegf antagonist to treat angiogenic eye disorders

Publications (2)

Publication Number Publication Date
MX2013007847A MX2013007847A (es) 2013-07-29
MX349901B true MX349901B (es) 2017-08-18

Family

ID=45507924

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2013007847A MX349901B (es) 2011-01-13 2012-01-11 Uso de un antagonista de factor de crecimiento endotelial vascular para tratar transtornos oculares angiogenicos.
MX2021006092A MX2021006092A (es) 2011-01-13 2013-07-04 Uso de un antagonista de factor de crecimiento endotelial vascular para tratar trastornos oculares angiogenicos.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2021006092A MX2021006092A (es) 2011-01-13 2013-07-04 Uso de un antagonista de factor de crecimiento endotelial vascular para tratar trastornos oculares angiogenicos.

Country Status (13)

Country Link
US (13) US9254338B2 (es)
EP (4) EP4360709A3 (es)
JP (5) JP2014503555A (es)
KR (7) KR20180023015A (es)
CN (1) CN103533950A (es)
AU (5) AU2012205599B2 (es)
BR (1) BR112013017752A8 (es)
CA (1) CA2824422A1 (es)
HK (1) HK1244693A1 (es)
IL (3) IL295359A (es)
MX (2) MX349901B (es)
SG (4) SG10201509193UA (es)
WO (1) WO2012097019A1 (es)

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Also Published As

Publication number Publication date
JP2021193115A (ja) 2021-12-23
KR20180023015A (ko) 2018-03-06
KR20220097542A (ko) 2022-07-07
US9254338B2 (en) 2016-02-09
KR20210030510A (ko) 2021-03-17
US20210085753A1 (en) 2021-03-25
IL295359A (en) 2022-10-01
EP3763379A1 (en) 2021-01-13
US20220273764A1 (en) 2022-09-01
KR20190049934A (ko) 2019-05-09
AU2012205599B2 (en) 2016-10-20
SG10201802789VA (en) 2018-05-30
HK1244693A1 (zh) 2018-08-17
EP4360709A3 (en) 2024-07-03
US20170202911A1 (en) 2017-07-20
AU2017200290B2 (en) 2019-01-03
US20210121524A1 (en) 2021-04-29
EP2663325A1 (en) 2013-11-20
US20210308216A1 (en) 2021-10-07
AU2012205599A1 (en) 2013-07-18
US10130681B2 (en) 2018-11-20
BR112013017752A8 (pt) 2018-01-09
SG10202111177VA (en) 2021-11-29
AU2019202260A1 (en) 2019-04-18
SG10201509193UA (en) 2015-12-30
US20130295094A1 (en) 2013-11-07
US11730794B2 (en) 2023-08-22
MX2013007847A (es) 2013-07-29
AU2017200290A1 (en) 2017-02-02
AU2024204677A1 (en) 2024-07-25
JP2014503555A (ja) 2014-02-13
SG191334A1 (en) 2013-08-30
US20160101152A1 (en) 2016-04-14
CA2824422A1 (en) 2012-07-19
KR20240110092A (ko) 2024-07-12
US10828345B2 (en) 2020-11-10
US20240123030A1 (en) 2024-04-18
IL260167A (en) 2018-07-31
EP4360709A2 (en) 2024-05-01
BR112013017752A2 (pt) 2017-08-29
EP3222285A1 (en) 2017-09-27
AU2021200935A1 (en) 2021-03-11
IL227160B (en) 2019-02-28
US11707506B2 (en) 2023-07-25
WO2012097019A1 (en) 2012-07-19
US11986511B2 (en) 2024-05-21
KR20140043313A (ko) 2014-04-09
KR20200077622A (ko) 2020-06-30
US20190247463A1 (en) 2019-08-15
CN103533950A (zh) 2014-01-22
US11975045B2 (en) 2024-05-07
MX2021006092A (es) 2022-05-18
US20190046609A1 (en) 2019-02-14
US10888601B2 (en) 2021-01-12
US20210308217A1 (en) 2021-10-07
US9669069B2 (en) 2017-06-06
US10857205B2 (en) 2020-12-08
JP2024001190A (ja) 2024-01-09
NZ612593A (en) 2015-03-27
US20180339018A1 (en) 2018-11-29
US11559564B2 (en) 2023-01-24
JP2017061467A (ja) 2017-03-30
US20210023173A1 (en) 2021-01-28
US11253572B2 (en) 2022-02-22
JP2019167366A (ja) 2019-10-03

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