JP2017036303A5 - - Google Patents
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- Publication number
- JP2017036303A5 JP2017036303A5 JP2016197813A JP2016197813A JP2017036303A5 JP 2017036303 A5 JP2017036303 A5 JP 2017036303A5 JP 2016197813 A JP2016197813 A JP 2016197813A JP 2016197813 A JP2016197813 A JP 2016197813A JP 2017036303 A5 JP2017036303 A5 JP 2017036303A5
- Authority
- JP
- Japan
- Prior art keywords
- gram
- nucleotide sequence
- repeat unit
- sequence encoding
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33217010P | 2010-05-06 | 2010-05-06 | |
| US61/332,170 | 2010-05-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508489A Division JP6339366B2 (ja) | 2010-05-06 | 2011-05-04 | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017036303A JP2017036303A (ja) | 2017-02-16 |
| JP2017036303A5 true JP2017036303A5 (enExample) | 2017-03-23 |
| JP6435583B2 JP6435583B2 (ja) | 2018-12-12 |
Family
ID=44902091
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508489A Expired - Fee Related JP6339366B2 (ja) | 2010-05-06 | 2011-05-04 | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
| JP2016197813A Expired - Fee Related JP6435583B2 (ja) | 2010-05-06 | 2016-10-06 | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508489A Expired - Fee Related JP6339366B2 (ja) | 2010-05-06 | 2011-05-04 | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US8871491B2 (enExample) |
| EP (2) | EP2566507B1 (enExample) |
| JP (2) | JP6339366B2 (enExample) |
| KR (2) | KR101916290B1 (enExample) |
| CN (1) | CN103079591B (enExample) |
| AU (2) | AU2011249839B2 (enExample) |
| CA (1) | CA2798381C (enExample) |
| CY (1) | CY1119895T1 (enExample) |
| DK (1) | DK2566507T3 (enExample) |
| ES (2) | ES2844596T3 (enExample) |
| HR (1) | HRP20180064T1 (enExample) |
| HU (1) | HUE037956T2 (enExample) |
| IL (1) | IL222711B (enExample) |
| LT (1) | LT2566507T (enExample) |
| NO (1) | NO2566507T3 (enExample) |
| PL (1) | PL2566507T3 (enExample) |
| PT (1) | PT2566507T (enExample) |
| SG (1) | SG185433A1 (enExample) |
| SI (1) | SI2566507T1 (enExample) |
| WO (1) | WO2011138361A1 (enExample) |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK1481057T3 (da) * | 2002-03-07 | 2006-05-15 | Eidgenoess Tech Hochschule | System og fremgangsmåde til fremstilling af rekombinante glycosylerede proteiner i en prokaryot vært |
| SI2257307T1 (sl) | 2008-02-20 | 2018-09-28 | Glaxosmithkline Biologicals S.A. | Biokonjugati, izdelani iz rekombinantnih N-glikoziliranih proteinov iz prokariontskih celic |
| NO2501406T3 (enExample) * | 2009-11-19 | 2018-05-19 | ||
| WO2013159234A1 (en) * | 2012-04-27 | 2013-10-31 | The Governors Of The University Of Alberta | Glycoengineered outer membrane vesicles and use thereof as vaccines |
| CA2879272A1 (en) | 2012-07-16 | 2014-01-23 | Robert G.K. DONALD | Saccharides and uses thereof |
| EP2877205A4 (en) | 2012-07-26 | 2016-04-06 | Jackson H M Found Military Med | VACCINE WITH A MULTIMED FUSION PROTEIN AND IMMUNOTHERAPY |
| KR20150068998A (ko) | 2012-10-12 | 2015-06-22 | 글리코박신 아게 | 숙주 세포 변형 방법 |
| EP2917351B1 (en) | 2012-11-07 | 2018-12-19 | GlaxoSmithKline Biologicals S.A. | Production of recombinant vaccine in e. coli by enzymatic conjugation |
| US9931392B2 (en) | 2013-01-18 | 2018-04-03 | London School Of Hygiene And Tropical Medicine | Glycosylation method |
| GB201301085D0 (en) * | 2013-01-22 | 2013-03-06 | London School Hygiene & Tropical Medicine | Glycoconjugate Vaccine |
| BR112016007727A8 (pt) * | 2013-10-11 | 2018-01-30 | Glycovaxyn Ag | célula hospedeira, e, método para produzir uma proteína n-glicosilada. |
| CN106163550A (zh) * | 2013-12-04 | 2016-11-23 | 格林考瓦因有限公司 | 通过大肠杆菌中合成的糖蛋白疫苗预防金黄色葡萄球菌感染 |
| MX378857B (es) * | 2014-04-17 | 2025-03-10 | Glaxosmithkline Biologicals Sa | Celulas huespedes modificadas y usos de las mismas. |
| AR104469A1 (es) * | 2014-08-08 | 2017-07-26 | Glycovaxyn Ag | Células huésped modificadas para su uso en producción de bioconjugados |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| US10500261B2 (en) | 2014-11-05 | 2019-12-10 | The United States Of America As Represented By The Secretary Of The Navy | Synthetic antigen constructs against campylobacter jejuni |
| JP2017537145A (ja) * | 2014-11-05 | 2017-12-14 | ザ ユナイテッド ステイツ オブ アメリカ アズ レプレゼンティッド バイ ザ セクレタリー オブ ザ ネイビーＴｈｅ Ｕｎｉｔｅｄ Ｓｔａｔｅｓ Ｏｆ Ａｍｅｒｉｃａ Ａｓ Ｒｅｐｒｅｓｅｎｔｅｄ Ｂｙ Ｔｈｅ Ｓｅｃｒｅｔａｒｙ Ｏｆ Ｔｈｅ Ｎａｖｙ | カンピロバクター・ジェジュニに対する合成抗原コンストラクト |
| SI3240895T1 (sl) | 2014-12-30 | 2022-04-29 | Glaxosmithkline Biologicals S.A. | Sestavki in postopki za glikozilacijo proteinov |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| EP3316904A1 (en) * | 2015-07-01 | 2018-05-09 | GlaxoSmithKline Biologicals S.A. | Immunogenic compositions |
| GB201518668D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Immunogenic Comosition |
| GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| GB201711635D0 (en) | 2017-07-19 | 2017-08-30 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| GB201712678D0 (en) | 2017-08-07 | 2017-09-20 | Glaxosmithkline Biologicals Sa | Process for the manipulation of nucleic acids |
| GB201721582D0 (en) * | 2017-12-21 | 2018-02-07 | Glaxosmithkline Biologicals Sa | S aureus antigens and immunogenic compositions |
| GB201721576D0 (en) | 2017-12-21 | 2018-02-07 | Glaxosmithkline Biologicals Sa | Hla antigens and glycoconjugates thereof |
| CN108330142B (zh) * | 2018-02-09 | 2021-09-17 | 河北科技师范学院 | 一种具有免疫保护作用的美人鱼发光杆菌溶血素Hlych蛋白 |
| GB201802339D0 (en) * | 2018-02-13 | 2018-03-28 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| US11260119B2 (en) | 2018-08-24 | 2022-03-01 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| CN109400704B (zh) * | 2018-11-14 | 2020-07-21 | 珠海泰诺麦博生物技术有限公司 | 一种抗金黄色葡萄球菌α-溶血素的抗体及其应用 |
| JP7551618B2 (ja) * | 2018-12-12 | 2024-09-17 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | Ｏ－結合型グリコシル化のための修飾キャリアタンパク質 |
| EP3908669A4 (en) * | 2019-01-11 | 2023-05-03 | Northwestern University | SYNTHESIS OF BIOCONJUGATED VACCINES IN PROKARYOT CELL LYSATE |
| EP3757217A1 (en) | 2019-06-27 | 2020-12-30 | GlaxoSmithKline Biologicals S.A. | Methods for protein purification |
| EP3770269A1 (en) * | 2019-07-23 | 2021-01-27 | GlaxoSmithKline Biologicals S.A. | Quantification of bioconjugate glycosylation |
| MX2022001606A (es) | 2019-08-09 | 2022-03-11 | Glaxosmithkline Biologicals Sa | Enzimas de oligosacariltransferasa pglb mutada. |
| EP3777884A1 (en) | 2019-08-15 | 2021-02-17 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
| CN112575041B (zh) * | 2019-09-30 | 2022-12-13 | 江南大学 | 一种混合碳源高效发酵生产phb的工程菌及其应用 |
| US20230226175A1 (en) * | 2020-06-25 | 2023-07-20 | Glaxosmithkline Biologicals Sa | Modified exotoxin a proteins |
| CN114085255B (zh) * | 2020-08-24 | 2023-08-29 | 山东大学 | 一种苏黎世克罗诺杆菌5型脂多糖o-抗原寡糖片段及其制备方法与应用 |
| US12138302B2 (en) | 2020-10-27 | 2024-11-12 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| US12357681B2 (en) | 2020-12-23 | 2025-07-15 | Pfizer Inc. | E. coli FimH mutants and uses thereof |
| US12680087B2 (en) | 2021-02-11 | 2026-07-14 | Glaxosmithkline Biologicals Sa | Mutated PGLB oligosaccharyltransferase enzymes |
| EP4452308A1 (en) | 2021-12-22 | 2024-10-30 | GlaxoSmithKline Biologicals S.A. | Vaccine |
| CN117940555B (zh) * | 2022-06-30 | 2025-05-30 | 上海羽冠生物技术有限公司 | 荚膜减少的活细菌菌株 |
| GB202302579D0 (en) | 2023-02-23 | 2023-04-12 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| KR20260052081A (ko) | 2023-08-09 | 2026-04-17 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 변형된 단백질 |
| KR20260051063A (ko) | 2023-08-09 | 2026-04-15 | 글락소스미스클라인 바이오로지칼즈 에스.에이. | 변형된 단백질 |
| CN117771264B (zh) * | 2023-11-27 | 2024-06-25 | 山东省农业科学院畜牧兽医研究所 | circHIF1α在制备抵御细菌感染的新型疫苗中的应用 |
| WO2025172892A1 (en) | 2024-02-16 | 2025-08-21 | Glaxosmithkline Biologicals Sa | Modified proteins and methods |
| CN120005900B (zh) * | 2025-01-21 | 2026-01-06 | 浙江大学 | FaCP5L1和FaCP5L3基因及其在调控果实成熟和采后保鲜品质中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1900A (en) | 1840-12-14 | Machine for extracting stumps | ||
| EP0170204B1 (de) | 1984-08-01 | 1991-09-25 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Neue genetische Sequenzen, die durch sie codierten Interferon-Peptide vom Typ I und diese sie produzierende Organismen |
| US5643758A (en) | 1987-03-10 | 1997-07-01 | New England Biolabs, Inc. | Production and purification of a protein fused to a binding protein |
| AU6663294A (en) | 1993-05-14 | 1994-12-12 | Upjohn Company, The | Cloned dna encoding a udp-galnac:polypeptide,n-acetylgalactos aminyltransferase |
| US6503744B1 (en) | 1999-02-01 | 2003-01-07 | National Research Council Of Canada | Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics |
| EP1399538A2 (en) | 1999-03-02 | 2004-03-24 | Human Genome Sciences, Inc. | Engineering intracellular sialylation pathways |
| NZ522320A (en) | 2000-05-12 | 2007-03-30 | Neose Technologies Inc | In vitro modification of glycosylation patterns of recombinant glycopeptides |
| EP2028275A3 (en) | 2000-06-30 | 2009-05-06 | VIB vzw | Protein glycosylation modification in pichia pastoris |
| JP4727927B2 (ja) | 2002-03-07 | 2011-07-20 | アイトゲネシシェ・テッヒニシェ・ホーホシューレ・チューリッヒ | 原核宿主における組換えグリコシル化タンパク質産生のためのシステムおよび方法 |
| DK1481057T3 (da) | 2002-03-07 | 2006-05-15 | Eidgenoess Tech Hochschule | System og fremgangsmåde til fremstilling af rekombinante glycosylerede proteiner i en prokaryot vært |
| CN1671722A (zh) | 2002-08-01 | 2005-09-21 | 加拿大国家研究院 | 弯曲菌的聚糖和糖肽 |
| EP2657251B1 (en) | 2004-05-24 | 2018-03-21 | The Government of The United States of America, as represented by The Secretary, Department of Health and Human Services | Live, oral vaccine for protection against Shigella dysenteriae serotype 1 |
| ES2535084T3 (es) * | 2005-05-11 | 2015-05-05 | Eth Zurich | Proteínas N-glicosiladas recombinantes procedentes de células procariotas |
| NZ570805A (en) | 2006-03-30 | 2011-10-28 | Glaxosmithkline Biolog Sa | Vaccine comprising Type 5 and Type 8 capsular polysaccharides from Staphyloccocus aureus |
| CN102037004A (zh) * | 2008-01-08 | 2011-04-27 | 生物种属学股份公司 | 使用寡糖基转移酶的多肽的糖缀合 |
| SI2257307T1 (sl) * | 2008-02-20 | 2018-09-28 | Glaxosmithkline Biologicals S.A. | Biokonjugati, izdelani iz rekombinantnih N-glikoziliranih proteinov iz prokariontskih celic |
-
2011
- 2011-05-04 WO PCT/EP2011/057111 patent/WO2011138361A1/en not_active Ceased
- 2011-05-04 KR KR1020187004586A patent/KR101916290B1/ko not_active Expired - Fee Related
- 2011-05-04 LT LTEP11724567.0T patent/LT2566507T/lt unknown
- 2011-05-04 DK DK11724567.0T patent/DK2566507T3/da active
- 2011-05-04 AU AU2011249839A patent/AU2011249839B2/en not_active Ceased
- 2011-05-04 CN CN201180033560.1A patent/CN103079591B/zh not_active Expired - Fee Related
- 2011-05-04 SG SG2012081535A patent/SG185433A1/en unknown
- 2011-05-04 CA CA2798381A patent/CA2798381C/en active Active
- 2011-05-04 SI SI201131403T patent/SI2566507T1/en unknown
- 2011-05-04 EP EP11724567.0A patent/EP2566507B1/en active Active
- 2011-05-04 ES ES17192866T patent/ES2844596T3/es active Active
- 2011-05-04 KR KR1020127031847A patent/KR20130063510A/ko not_active Ceased
- 2011-05-04 ES ES11724567.0T patent/ES2657588T3/es active Active
- 2011-05-04 JP JP2013508489A patent/JP6339366B2/ja not_active Expired - Fee Related
- 2011-05-04 PL PL11724567T patent/PL2566507T3/pl unknown
- 2011-05-04 US US13/100,603 patent/US8871491B2/en active Active
- 2011-05-04 HU HUE11724567A patent/HUE037956T2/hu unknown
- 2011-05-04 NO NO11724567A patent/NO2566507T3/no unknown
- 2011-05-04 HR HRP20180064TT patent/HRP20180064T1/hr unknown
- 2011-05-04 PT PT117245670T patent/PT2566507T/pt unknown
- 2011-05-04 EP EP17192866.6A patent/EP3281639B1/en active Active
-
2012
- 2012-10-25 IL IL222711A patent/IL222711B/en active IP Right Grant
-
2014
- 2014-09-23 US US14/494,150 patent/US9585950B2/en not_active Expired - Fee Related
-
2016
- 2016-07-25 AU AU2016208265A patent/AU2016208265A1/en not_active Abandoned
- 2016-10-06 JP JP2016197813A patent/JP6435583B2/ja not_active Expired - Fee Related
-
2017
- 2017-01-25 US US15/414,900 patent/US10307473B2/en active Active
-
2018
- 2018-02-06 CY CY20181100148T patent/CY1119895T1/el unknown
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