JP2017036303A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2017036303A5 JP2017036303A5 JP2016197813A JP2016197813A JP2017036303A5 JP 2017036303 A5 JP2017036303 A5 JP 2017036303A5 JP 2016197813 A JP2016197813 A JP 2016197813A JP 2016197813 A JP2016197813 A JP 2016197813A JP 2017036303 A5 JP2017036303 A5 JP 2017036303A5
- Authority
- JP
- Japan
- Prior art keywords
- gram
- nucleotide sequence
- repeat unit
- sequence encoding
- protein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US33217010P | 2010-05-06 | 2010-05-06 | |
| US61/332,170 | 2010-05-06 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508489A Division JP6339366B2 (ja) | 2010-05-06 | 2011-05-04 | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017036303A JP2017036303A (ja) | 2017-02-16 |
| JP2017036303A5 true JP2017036303A5 (enExample) | 2017-03-23 |
| JP6435583B2 JP6435583B2 (ja) | 2018-12-12 |
Family
ID=44902091
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508489A Expired - Fee Related JP6339366B2 (ja) | 2010-05-06 | 2011-05-04 | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
| JP2016197813A Expired - Fee Related JP6435583B2 (ja) | 2010-05-06 | 2016-10-06 | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013508489A Expired - Fee Related JP6339366B2 (ja) | 2010-05-06 | 2011-05-04 | 莢膜グラム陽性菌のバイオコンジュゲートワクチン |
Country Status (20)
| Country | Link |
|---|---|
| US (3) | US8871491B2 (enExample) |
| EP (2) | EP3281639B1 (enExample) |
| JP (2) | JP6339366B2 (enExample) |
| KR (2) | KR101916290B1 (enExample) |
| CN (1) | CN103079591B (enExample) |
| AU (2) | AU2011249839B2 (enExample) |
| CA (1) | CA2798381C (enExample) |
| CY (1) | CY1119895T1 (enExample) |
| DK (1) | DK2566507T3 (enExample) |
| ES (2) | ES2657588T3 (enExample) |
| HR (1) | HRP20180064T1 (enExample) |
| HU (1) | HUE037956T2 (enExample) |
| IL (1) | IL222711B (enExample) |
| LT (1) | LT2566507T (enExample) |
| NO (1) | NO2566507T3 (enExample) |
| PL (1) | PL2566507T3 (enExample) |
| PT (1) | PT2566507T (enExample) |
| SG (1) | SG185433A1 (enExample) |
| SI (1) | SI2566507T1 (enExample) |
| WO (1) | WO2011138361A1 (enExample) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT1481057E (pt) * | 2002-03-07 | 2006-05-31 | Eidgenoess Tech Hochschule | Sistema e metodo para a producao de proteinas glicosiladas recombinantes num hospedeiro procariota |
| LT2257307T (lt) | 2008-02-20 | 2018-08-10 | Glaxosmithkline Biologicals S.A. | Biokonjugatai, gauti iš rekombinantinių n-glikozilintų baltymų iš prokariotinių ląstelių |
| CN102724997B (zh) | 2009-11-19 | 2016-09-21 | 格林考瓦因有限公司 | 在原核细胞中产生免疫原性多糖的生物合成系统 |
| WO2013159234A1 (en) | 2012-04-27 | 2013-10-31 | The Governors Of The University Of Alberta | Glycoengineered outer membrane vesicles and use thereof as vaccines |
| WO2014013375A1 (en) | 2012-07-16 | 2014-01-23 | Pfizer Inc. | Saccharides and uses thereof |
| EP2877205A4 (en) | 2012-07-26 | 2016-04-06 | Jackson H M Found Military Med | VACCINE WITH A MULTIMED FUSION PROTEIN AND IMMUNOTHERAPY |
| ES2720040T3 (es) | 2012-10-12 | 2019-07-17 | Glaxosmithkline Biologicals Sa | Procedimientos de modificación de células hospedadoras |
| US20150273043A1 (en) | 2012-11-07 | 2015-10-01 | Glycovaxyn Ag | Production of recombinant vaccine in e.coli by enzymatic conjugation |
| CA2923957C (en) | 2013-01-18 | 2021-08-31 | London School Of Hygiene And Tropical Medicine | Glycosylation method |
| GB201301085D0 (en) * | 2013-01-22 | 2013-03-06 | London School Hygiene & Tropical Medicine | Glycoconjugate Vaccine |
| CA2926523C (en) * | 2013-10-11 | 2023-09-26 | Glycovaxyn Ag | Methods of host cell modification |
| JP2016540764A (ja) * | 2013-12-04 | 2016-12-28 | グリコヴァキシン アーゲー | 大腸菌で合成された糖タンパク質ワクチンによる黄色ブドウ球菌感染の予防 |
| HUE049806T2 (hu) * | 2014-04-17 | 2020-10-28 | Glaxosmithkline Biologicals Sa | Módosított gazdasejtek és alkalmazásaik |
| US10307474B2 (en) * | 2014-08-08 | 2019-06-04 | Glaxosmithkline Biologicals S.A. | Modified host cells and hybrid oligosaccharides for use in bioconjugate production |
| US9616114B1 (en) | 2014-09-18 | 2017-04-11 | David Gordon Bermudes | Modified bacteria having improved pharmacokinetics and tumor colonization enhancing antitumor activity |
| AU2015342943B2 (en) * | 2014-11-05 | 2018-06-28 | The United States Of America As Represented By The Secretary Of The Navy | Synthetic antigen constructs against Campylobacter jejuni |
| US10500261B2 (en) | 2014-11-05 | 2019-12-10 | The United States Of America As Represented By The Secretary Of The Navy | Synthetic antigen constructs against campylobacter jejuni |
| DK3240895T3 (da) | 2014-12-30 | 2022-04-11 | Glaxosmithkline Biologicals Sa | Sammensætninger og fremgangsmåder til proteinglykosylering |
| US10676723B2 (en) | 2015-05-11 | 2020-06-09 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| US20200030430A1 (en) * | 2015-07-01 | 2020-01-30 | Glaxosmithkline Biologicals Sa | Immunogenic compositions |
| GB201518668D0 (en) | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Immunogenic Comosition |
| GB201610599D0 (en) | 2016-06-17 | 2016-08-03 | Glaxosmithkline Biologicals Sa | Immunogenic Composition |
| US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| GB201712678D0 (en) | 2017-08-07 | 2017-09-20 | Glaxosmithkline Biologicals Sa | Process for the manipulation of nucleic acids |
| GB201721582D0 (en) * | 2017-12-21 | 2018-02-07 | Glaxosmithkline Biologicals Sa | S aureus antigens and immunogenic compositions |
| GB201721576D0 (en) | 2017-12-21 | 2018-02-07 | Glaxosmithkline Biologicals Sa | Hla antigens and glycoconjugates thereof |
| CN108330142B (zh) * | 2018-02-09 | 2021-09-17 | 河北科技师范学院 | 一种具有免疫保护作用的美人鱼发光杆菌溶血素Hlych蛋白 |
| GB201802339D0 (en) | 2018-02-13 | 2018-03-28 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| US11260119B2 (en) | 2018-08-24 | 2022-03-01 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| CN109400704B (zh) * | 2018-11-14 | 2020-07-21 | 珠海泰诺麦博生物技术有限公司 | 一种抗金黄色葡萄球菌α-溶血素的抗体及其应用 |
| EP3894431A2 (en) | 2018-12-12 | 2021-10-20 | GlaxoSmithKline Biologicals SA | Modified carrier proteins for o-linked glycosylation |
| CN113646438A (zh) * | 2019-01-11 | 2021-11-12 | 西北大学 | 在原核生物细胞裂解物中合成生物缀合物疫苗 |
| EP3757217A1 (en) | 2019-06-27 | 2020-12-30 | GlaxoSmithKline Biologicals S.A. | Methods for protein purification |
| EP3770269A1 (en) | 2019-07-23 | 2021-01-27 | GlaxoSmithKline Biologicals S.A. | Quantification of bioconjugate glycosylation |
| PL4010467T3 (pl) | 2019-08-09 | 2024-08-05 | Glaxosmithkline Biologicals Sa | Zmutowane enzymy oligosacharylotransferazy pglb |
| EP3777884A1 (en) | 2019-08-15 | 2021-02-17 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
| CN112575041B (zh) * | 2019-09-30 | 2022-12-13 | 江南大学 | 一种混合碳源高效发酵生产phb的工程菌及其应用 |
| CN115996749A (zh) | 2020-06-25 | 2023-04-21 | 葛兰素史克生物有限公司 | 经修饰的外毒素a蛋白 |
| CN114085255B (zh) * | 2020-08-24 | 2023-08-29 | 山东大学 | 一种苏黎世克罗诺杆菌5型脂多糖o-抗原寡糖片段及其制备方法与应用 |
| US12138302B2 (en) | 2020-10-27 | 2024-11-12 | Pfizer Inc. | Escherichia coli compositions and methods thereof |
| US12357681B2 (en) | 2020-12-23 | 2025-07-15 | Pfizer Inc. | E. coli FimH mutants and uses thereof |
| WO2022171679A2 (en) | 2021-02-11 | 2022-08-18 | Glaxosmithkline Biologicals Sa | Protein |
| WO2023118033A1 (en) | 2021-12-22 | 2023-06-29 | Glaxosmithkline Biologicals Sa | Vaccine |
| WO2024002331A1 (en) * | 2022-06-30 | 2024-01-04 | Shanghai Yuguan Biotech Co., Ltd. | A live bacteria strain with reduced capsules |
| GB202302579D0 (en) | 2023-02-23 | 2023-04-12 | Glaxosmithkline Biologicals Sa | Immunogenic composition |
| WO2025032534A2 (en) | 2023-08-09 | 2025-02-13 | Glaxosmithkline Biologicals Sa | Modified proteins |
| WO2025032535A2 (en) | 2023-08-09 | 2025-02-13 | Glaxosmithkline Biologicals Sa | Modified proteins |
| CN117771264B (zh) * | 2023-11-27 | 2024-06-25 | 山东省农业科学院畜牧兽医研究所 | circHIF1α在制备抵御细菌感染的新型疫苗中的应用 |
| WO2025172892A1 (en) | 2024-02-16 | 2025-08-21 | Glaxosmithkline Biologicals Sa | Modified proteins and methods |
| CN120005900B (zh) * | 2025-01-21 | 2026-01-06 | 浙江大学 | FaCP5L1和FaCP5L3基因及其在调控果实成熟和采后保鲜品质中的应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1900A (en) | 1840-12-14 | Machine for extracting stumps | ||
| EP0170204B1 (de) | 1984-08-01 | 1991-09-25 | BOEHRINGER INGELHEIM INTERNATIONAL GmbH | Neue genetische Sequenzen, die durch sie codierten Interferon-Peptide vom Typ I und diese sie produzierende Organismen |
| US5643758A (en) | 1987-03-10 | 1997-07-01 | New England Biolabs, Inc. | Production and purification of a protein fused to a binding protein |
| AU6663294A (en) | 1993-05-14 | 1994-12-12 | Upjohn Company, The | Cloned dna encoding a udp-galnac:polypeptide,n-acetylgalactos aminyltransferase |
| US6503744B1 (en) | 1999-02-01 | 2003-01-07 | National Research Council Of Canada | Campylobacter glycosyltransferases for biosynthesis of gangliosides and ganglioside mimics |
| AU3508300A (en) | 1999-03-02 | 2000-09-21 | Human Genome Sciences, Inc. | Engineering intracellular sialylation pathways |
| EP1285072A2 (en) | 2000-05-12 | 2003-02-26 | Neose Technologies, Inc. | In vitro fucosylation recombinant glycopeptides |
| WO2002000856A2 (en) | 2000-06-30 | 2002-01-03 | Flanders Interuniversity Institute For Biotechnology (Vib) | Protein glycosylation modification in pichia pastoris |
| KR20100119905A (ko) | 2002-03-07 | 2010-11-11 | 아이드게노쉬쉐 테흐니쉐 호흐슐레 쥬리히 | 원핵 숙주에서의 재조합 글리코실화 단백질 생산 방법 및 생산계 |
| PT1481057E (pt) | 2002-03-07 | 2006-05-31 | Eidgenoess Tech Hochschule | Sistema e metodo para a producao de proteinas glicosiladas recombinantes num hospedeiro procariota |
| US7598354B2 (en) | 2002-08-01 | 2009-10-06 | National Research Council Of Canada | Campylobacter glycans and glycopeptides |
| EP1756149B1 (en) | 2004-05-24 | 2013-09-04 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Live, oral vaccine for protection against shigella dysenteriae serotype 1 |
| DK1888761T3 (da) | 2005-05-11 | 2010-11-01 | Eth Zuerich | Rekombinante N-glycosylerede proteiner fra prokaryote celler |
| EP1998802A2 (en) | 2006-03-30 | 2008-12-10 | GlaxoSmithKline Biologicals S.A. | Immunogenic composition |
| WO2009089396A2 (en) * | 2008-01-08 | 2009-07-16 | Neose Technologies, Inc. | Glycoconjugation of polypeptides using oligosaccharyltransferases |
| LT2257307T (lt) * | 2008-02-20 | 2018-08-10 | Glaxosmithkline Biologicals S.A. | Biokonjugatai, gauti iš rekombinantinių n-glikozilintų baltymų iš prokariotinių ląstelių |
-
2011
- 2011-05-04 JP JP2013508489A patent/JP6339366B2/ja not_active Expired - Fee Related
- 2011-05-04 EP EP17192866.6A patent/EP3281639B1/en active Active
- 2011-05-04 HU HUE11724567A patent/HUE037956T2/hu unknown
- 2011-05-04 CN CN201180033560.1A patent/CN103079591B/zh not_active Expired - Fee Related
- 2011-05-04 AU AU2011249839A patent/AU2011249839B2/en not_active Ceased
- 2011-05-04 CA CA2798381A patent/CA2798381C/en active Active
- 2011-05-04 WO PCT/EP2011/057111 patent/WO2011138361A1/en not_active Ceased
- 2011-05-04 ES ES11724567.0T patent/ES2657588T3/es active Active
- 2011-05-04 PL PL11724567T patent/PL2566507T3/pl unknown
- 2011-05-04 NO NO11724567A patent/NO2566507T3/no unknown
- 2011-05-04 DK DK11724567.0T patent/DK2566507T3/da active
- 2011-05-04 LT LTEP11724567.0T patent/LT2566507T/lt unknown
- 2011-05-04 PT PT117245670T patent/PT2566507T/pt unknown
- 2011-05-04 SI SI201131403T patent/SI2566507T1/en unknown
- 2011-05-04 US US13/100,603 patent/US8871491B2/en active Active
- 2011-05-04 EP EP11724567.0A patent/EP2566507B1/en active Active
- 2011-05-04 SG SG2012081535A patent/SG185433A1/en unknown
- 2011-05-04 HR HRP20180064TT patent/HRP20180064T1/hr unknown
- 2011-05-04 KR KR1020187004586A patent/KR101916290B1/ko not_active Expired - Fee Related
- 2011-05-04 ES ES17192866T patent/ES2844596T3/es active Active
- 2011-05-04 KR KR1020127031847A patent/KR20130063510A/ko not_active Ceased
-
2012
- 2012-10-25 IL IL222711A patent/IL222711B/en active IP Right Grant
-
2014
- 2014-09-23 US US14/494,150 patent/US9585950B2/en not_active Expired - Fee Related
-
2016
- 2016-07-25 AU AU2016208265A patent/AU2016208265A1/en not_active Abandoned
- 2016-10-06 JP JP2016197813A patent/JP6435583B2/ja not_active Expired - Fee Related
-
2017
- 2017-01-25 US US15/414,900 patent/US10307473B2/en active Active
-
2018
- 2018-02-06 CY CY20181100148T patent/CY1119895T1/el unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2017036303A5 (enExample) | ||
| JP2013524844A5 (enExample) | ||
| Okura et al. | Genetic analysis of capsular polysaccharide synthesis gene clusters from all serotypes of Streptococcus suis: potential mechanisms for generation of capsular variation | |
| MX2022003994A (es) | Produccion de oligosacaridos de leche humana en huespedes microbianos con importacion/exportacion dise?ada. | |
| JP2015533511A5 (enExample) | ||
| Sengupta et al. | The role of cell surface architecture of lactobacilli in host‐microbe interactions in the gastrointestinal tract | |
| FI3110441T3 (fi) | Uusi polysakkaridi ja sen käyttöjä | |
| PH12013501536A1 (en) | Novel fucosyltransferases and their applications | |
| PH12017501898A1 (en) | Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof | |
| JP2015214545A5 (enExample) | ||
| WO2019002218A3 (en) | MODIFICATION OF MICROBIAL POPULATIONS AND MODIFICATION OF MICROBIOTA | |
| CA2438080A1 (en) | Gonococcal proteins and nucleic acids | |
| RU2014151746A (ru) | Штаммы lactobacillus | |
| WO2015110942A3 (en) | Streptococcus pneumoniae capsular polysaccharides and conjugates thereof | |
| JP2013079285A5 (enExample) | ||
| HRP20201021T1 (hr) | Modificirane stanice domaćini i njihova upotreba | |
| JP2017529849A5 (enExample) | ||
| AU2020240075A8 (en) | Methods of producing bioconjugates of e. coli o-antigen polysaccharides, compositions thereof, and methods of use thereof | |
| CN110036108A (zh) | 一种细菌β-1,3-葡聚糖酶及其编码基因与应用 | |
| JOP20190038B1 (ar) | تركيب اقتراني من السكر المتعدد لكبسولة بكتيريا المكورات الرئوية وبروتين حامل واستخداماته | |
| Berendsen et al. | Draft genome sequences of seven thermophilic spore-forming bacteria isolated from foods that produce highly heat-resistant spores, comprising Geobacillus spp., Caldibacillus debilis, and Anoxybacillus flavithermus | |
| Damé-Teixeira et al. | Genotypic diversity and virulence traits of Streptococcus mutans isolated from carious dentin after partial caries removal and sealing | |
| PH12019500843A1 (en) | Vaccine contructs and uses thereof against staphylococcus infections | |
| WO2010115278A8 (en) | Methods and compositions for treating and preventing shiga toxin-producing escherichia coli infection | |
| Peng et al. | Genomic insights into the pathogenicity and environmental adaptability of Enterococcus hirae R17 isolated from pork offered for retail sale |