JP2015533511A5 - - Google Patents

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Publication number
JP2015533511A5
JP2015533511A5 JP2015541130A JP2015541130A JP2015533511A5 JP 2015533511 A5 JP2015533511 A5 JP 2015533511A5 JP 2015541130 A JP2015541130 A JP 2015541130A JP 2015541130 A JP2015541130 A JP 2015541130A JP 2015533511 A5 JP2015533511 A5 JP 2015533511A5
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JP
Japan
Prior art keywords
gram
negative bacterium
pneumoniae
gene
coli
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JP2015541130A
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English (en)
Japanese (ja)
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JP2015533511A (ja
JP6412875B2 (ja
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Priority claimed from PCT/EP2013/073266 external-priority patent/WO2014072405A1/en
Publication of JP2015533511A publication Critical patent/JP2015533511A/ja
Publication of JP2015533511A5 publication Critical patent/JP2015533511A5/ja
Application granted granted Critical
Publication of JP6412875B2 publication Critical patent/JP6412875B2/ja
Expired - Fee Related legal-status Critical Current
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JP2015541130A 2012-11-07 2013-11-07 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造 Expired - Fee Related JP6412875B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261723408P 2012-11-07 2012-11-07
US61/723,408 2012-11-07
PCT/EP2013/073266 WO2014072405A1 (en) 2012-11-07 2013-11-07 Production of recombinant vaccine in e. coli by enzymatic conjugation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018186302A Division JP6833785B2 (ja) 2012-11-07 2018-10-01 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造

Publications (3)

Publication Number Publication Date
JP2015533511A JP2015533511A (ja) 2015-11-26
JP2015533511A5 true JP2015533511A5 (enExample) 2016-12-22
JP6412875B2 JP6412875B2 (ja) 2018-10-24

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Application Number Title Priority Date Filing Date
JP2015541130A Expired - Fee Related JP6412875B2 (ja) 2012-11-07 2013-11-07 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造
JP2018186302A Expired - Fee Related JP6833785B2 (ja) 2012-11-07 2018-10-01 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造

Family Applications After (1)

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JP2018186302A Expired - Fee Related JP6833785B2 (ja) 2012-11-07 2018-10-01 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造

Country Status (16)

Country Link
US (2) US20150273043A1 (enExample)
EP (3) EP3444352B1 (enExample)
JP (2) JP6412875B2 (enExample)
KR (1) KR20150079964A (enExample)
CN (1) CN105008539B (enExample)
AU (2) AU2013343520B2 (enExample)
BR (1) BR112015010283A8 (enExample)
CA (2) CA2889767C (enExample)
EA (1) EA201590705A1 (enExample)
ES (3) ES2713166T3 (enExample)
IL (1) IL238586A0 (enExample)
MX (1) MX366912B (enExample)
SG (1) SG11201503308XA (enExample)
TR (1) TR201903066T4 (enExample)
WO (1) WO2014072405A1 (enExample)
ZA (1) ZA201503097B (enExample)

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AU2010322454B2 (en) * 2009-11-19 2016-05-19 Glaxosmithkline Biologicals S.A. Biosynthetic system that produces immunogenic polysaccharides in prokaryotic cells
US11220676B2 (en) * 2013-10-11 2022-01-11 Glaxosmithkline Biological Sa Methods of host cell modification
EA035991B9 (ru) 2014-02-24 2020-10-21 Глаксосмитклайн Байолоджикалс С.А. Новый полисахарид и его применения
SI3131577T1 (sl) * 2014-04-17 2020-08-31 Glaxosmithkline Biologicals S.A. Modificirane gostiljske celice in uporabe le-teh
SG11201700325SA (en) * 2014-08-08 2017-02-27 Glycovaxyn Ag Modified host cells and hybrid oligosaccharides for use in bioconjugate production
AU2016224006B8 (en) * 2015-02-26 2020-03-19 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
GB201518668D0 (en) * 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Immunogenic Comosition
GB201610599D0 (en) 2016-06-17 2016-08-03 Glaxosmithkline Biologicals Sa Immunogenic Composition
CN105963691B (zh) * 2016-07-03 2020-05-01 查文娟 一种肺炎链球菌疫苗
CN106929573B (zh) * 2017-02-21 2020-06-09 南开大学 对嗜肺军团菌O12型的wzm和wecA基因特异的核苷酸序列及其应用
GB201712678D0 (en) * 2017-08-07 2017-09-20 Glaxosmithkline Biologicals Sa Process for the manipulation of nucleic acids
WO2019043245A1 (en) * 2017-09-04 2019-03-07 London School Of Hygiene And Tropical Medicine MICROBIAL CELLS EXPRESSING STREPTOCOCCAL SERROTYPES
WO2019090138A2 (en) * 2017-11-04 2019-05-09 Board Of Regents Of The Nevada System Of Higher Education, On Behalf Of The University Of Nevada, Reno Immunogenic conjugates and methods of use thereof
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
WO2019241672A2 (en) 2018-06-16 2019-12-19 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
US11260119B2 (en) 2018-08-24 2022-03-01 Pfizer Inc. Escherichia coli compositions and methods thereof
EP3650044A1 (en) * 2018-11-06 2020-05-13 ETH Zürich Anti-glycan vaccines
US12350342B2 (en) 2018-12-21 2025-07-08 Vaxnewmo Llc O-linked glycosylation recognition motifs
IL286467B1 (en) 2019-03-18 2025-10-01 Janssen Pharmaceuticals Inc Methods for producing bioconjugates of E. COLI O-antigen polysaccharides, preparations thereof and methods for using them
EP3770269A1 (en) 2019-07-23 2021-01-27 GlaxoSmithKline Biologicals S.A. Quantification of bioconjugate glycosylation
CN112369722B (zh) * 2020-05-08 2023-03-17 湖北中烟工业有限责任公司 加热不燃烧装置和温度控制方法
CN111518738B (zh) * 2020-05-08 2022-02-08 徐州海润生物科技有限公司 重组卡介苗及其制备方法和应用
CA3185719A1 (en) * 2020-06-18 2021-12-23 Glaxosmithkline Biologicals Sa Shigella-tetravalent (shigella4v) bioconjugate
US20230293657A1 (en) 2020-06-25 2023-09-21 Glaxosmithkline Biologicals Sa Vaccine
KR20230043157A (ko) 2020-09-17 2023-03-30 얀센 파마슈티칼즈, 인코포레이티드 다가 백신 조성물 및 이의 용도
US12138302B2 (en) 2020-10-27 2024-11-12 Pfizer Inc. Escherichia coli compositions and methods thereof
US12357681B2 (en) 2020-12-23 2025-07-15 Pfizer Inc. E. coli FimH mutants and uses thereof
EP4452308A1 (en) 2021-12-22 2024-10-30 GlaxoSmithKline Biologicals S.A. Vaccine
GB202302579D0 (en) 2023-02-23 2023-04-12 Glaxosmithkline Biologicals Sa Immunogenic composition
WO2025172892A1 (en) 2024-02-16 2025-08-21 Glaxosmithkline Biologicals Sa Modified proteins and methods

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AU2638595A (en) * 1994-05-16 1995-12-05 Uab Research Foundation, The (streptococcus pneumoniae) capsular polysaccharide genes and flanking regions
US7018637B2 (en) 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
US7541043B2 (en) 2002-01-16 2009-06-02 The United States Of America As Represented By The Department Of Health And Human Services Vaccine for protection against Shigella sonnei disease
CA2477794C (en) 2002-03-07 2013-08-20 Eidgenoessische Technische Hochschule Zuerich System and method for the production of recombinant glycosylated proteins in a prokaryotic host
JP5356807B2 (ja) 2005-05-11 2013-12-04 アイトヘネーシシェ テフニーシェ ホフシューレ チューリッヒ 原核細胞由来の組み換えn−グリコシル化タンパク質
HRP20181259T1 (hr) 2008-02-20 2018-10-05 Glaxosmithkline Biologicals S.A. Biokonjugati načinjeni iz rekombinantnih n-glikoziliranih proteina iz prokariotskih stanica
CA2756170C (en) * 2009-03-23 2019-04-02 The Brigham And Women's Hospital, Inc. Glycoconjugate vaccines
KR20120085240A (ko) 2009-07-17 2012-07-31 오션 하베스트 테크놀로지 (캐나다) 아이엔씨. 어류 사료에서 합성 첨가제를 대체하는 천연 및 지속 가능 해조류 배합
ES2844596T3 (es) 2010-05-06 2021-07-22 Glaxosmithkline Biologicals Sa Vacunas de bioconjugados de bacterias grampositivas capsulares
TR201904022T4 (tr) * 2012-10-12 2019-04-22 Glaxosmithkline Biologicals Sa Konakçı hücre modifikasyon yöntemleri.

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