JP2015533511A5 - - Google Patents

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Publication number
JP2015533511A5
JP2015533511A5 JP2015541130A JP2015541130A JP2015533511A5 JP 2015533511 A5 JP2015533511 A5 JP 2015533511A5 JP 2015541130 A JP2015541130 A JP 2015541130A JP 2015541130 A JP2015541130 A JP 2015541130A JP 2015533511 A5 JP2015533511 A5 JP 2015533511A5
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JP
Japan
Prior art keywords
gram
negative bacterium
pneumoniae
gene
coli
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JP2015541130A
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English (en)
Japanese (ja)
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JP2015533511A (ja
JP6412875B2 (ja
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Priority claimed from PCT/EP2013/073266 external-priority patent/WO2014072405A1/en
Publication of JP2015533511A publication Critical patent/JP2015533511A/ja
Publication of JP2015533511A5 publication Critical patent/JP2015533511A5/ja
Application granted granted Critical
Publication of JP6412875B2 publication Critical patent/JP6412875B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015541130A 2012-11-07 2013-11-07 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造 Expired - Fee Related JP6412875B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261723408P 2012-11-07 2012-11-07
US61/723,408 2012-11-07
PCT/EP2013/073266 WO2014072405A1 (en) 2012-11-07 2013-11-07 Production of recombinant vaccine in e. coli by enzymatic conjugation

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018186302A Division JP6833785B2 (ja) 2012-11-07 2018-10-01 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造

Publications (3)

Publication Number Publication Date
JP2015533511A JP2015533511A (ja) 2015-11-26
JP2015533511A5 true JP2015533511A5 (enExample) 2016-12-22
JP6412875B2 JP6412875B2 (ja) 2018-10-24

Family

ID=49552366

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015541130A Expired - Fee Related JP6412875B2 (ja) 2012-11-07 2013-11-07 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造
JP2018186302A Expired - Fee Related JP6833785B2 (ja) 2012-11-07 2018-10-01 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造

Family Applications After (1)

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JP2018186302A Expired - Fee Related JP6833785B2 (ja) 2012-11-07 2018-10-01 酵素的コンジュゲート化による大腸菌での組み換えワクチンの製造

Country Status (16)

Country Link
US (2) US20150273043A1 (enExample)
EP (3) EP2917351B1 (enExample)
JP (2) JP6412875B2 (enExample)
KR (1) KR20150079964A (enExample)
CN (1) CN105008539B (enExample)
AU (2) AU2013343520B2 (enExample)
BR (1) BR112015010283A8 (enExample)
CA (2) CA2889767C (enExample)
EA (1) EA201590705A1 (enExample)
ES (3) ES2882282T3 (enExample)
IL (1) IL238586A0 (enExample)
MX (1) MX366912B (enExample)
SG (1) SG11201503308XA (enExample)
TR (1) TR201903066T4 (enExample)
WO (1) WO2014072405A1 (enExample)
ZA (1) ZA201503097B (enExample)

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NO2501406T3 (enExample) * 2009-11-19 2018-05-19
BR112016007727A8 (pt) * 2013-10-11 2018-01-30 Glycovaxyn Ag célula hospedeira, e, método para produzir uma proteína n-glicosilada.
NZ723328A (en) 2014-02-24 2018-01-26 Glycovaxyn Ag Compositions comprising e. coli o25b antigen, uses thereof and methods of manufacture
MX378857B (es) * 2014-04-17 2025-03-10 Glaxosmithkline Biologicals Sa Celulas huespedes modificadas y usos de las mismas.
AR104469A1 (es) 2014-08-08 2017-07-26 Glycovaxyn Ag Células huésped modificadas para su uso en producción de bioconjugados
US10265391B2 (en) * 2015-02-26 2019-04-23 Vaxnewmo Llc Acinetobacter O-oligosaccharyltransferases and uses thereof
GB201518668D0 (en) * 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Immunogenic Comosition
GB201610599D0 (en) 2016-06-17 2016-08-03 Glaxosmithkline Biologicals Sa Immunogenic Composition
CN105963691B (zh) * 2016-07-03 2020-05-01 查文娟 一种肺炎链球菌疫苗
CN106929573B (zh) * 2017-02-21 2020-06-09 南开大学 对嗜肺军团菌O12型的wzm和wecA基因特异的核苷酸序列及其应用
GB201711635D0 (en) 2017-07-19 2017-08-30 Glaxosmithkline Biologicals Sa Immunogenic composition
GB201712678D0 (en) 2017-08-07 2017-09-20 Glaxosmithkline Biologicals Sa Process for the manipulation of nucleic acids
WO2019043245A1 (en) * 2017-09-04 2019-03-07 London School Of Hygiene And Tropical Medicine MICROBIAL CELLS EXPRESSING STREPTOCOCCAL SERROTYPES
US11235046B2 (en) 2017-11-04 2022-02-01 Nevada Research & Innovation Corporation Immunogenic conjugates and methods of use thereof
GB201721582D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa S aureus antigens and immunogenic compositions
GB201721576D0 (en) 2017-12-21 2018-02-07 Glaxosmithkline Biologicals Sa Hla antigens and glycoconjugates thereof
ES3051337T3 (en) 2018-06-16 2025-12-26 Vaxnewmo Llc Glycosylated comp pilin variants, methods of making and uses thereof
US11260119B2 (en) 2018-08-24 2022-03-01 Pfizer Inc. Escherichia coli compositions and methods thereof
EP3650044A1 (en) * 2018-11-06 2020-05-13 ETH Zürich Anti-glycan vaccines
US12350342B2 (en) 2018-12-21 2025-07-08 Vaxnewmo Llc O-linked glycosylation recognition motifs
IL286467B2 (en) 2019-03-18 2026-02-01 Janssen Pharmaceuticals Inc Methods for producing bioconjugates of polysaccharides E. coli o-antigen, preparations thereof and methods for using them
EP3770269A1 (en) 2019-07-23 2021-01-27 GlaxoSmithKline Biologicals S.A. Quantification of bioconjugate glycosylation
CN112369722B (zh) * 2020-05-08 2023-03-17 湖北中烟工业有限责任公司 加热不燃烧装置和温度控制方法
CN111518738B (zh) 2020-05-08 2022-02-08 徐州海润生物科技有限公司 重组卡介苗及其制备方法和应用
CA3185719A1 (en) * 2020-06-18 2021-12-23 Glaxosmithkline Biologicals Sa Shigella-tetravalent (shigella4v) bioconjugate
US20230226175A1 (en) 2020-06-25 2023-07-20 Glaxosmithkline Biologicals Sa Modified exotoxin a proteins
PE20231385A1 (es) 2020-09-17 2023-09-12 Janssen Pharmaceuticals Inc Composiciones de vacunas multivalentes y usos de las mismas
US12138302B2 (en) 2020-10-27 2024-11-12 Pfizer Inc. Escherichia coli compositions and methods thereof
US12357681B2 (en) 2020-12-23 2025-07-15 Pfizer Inc. E. coli FimH mutants and uses thereof
EP4452308A1 (en) 2021-12-22 2024-10-30 GlaxoSmithKline Biologicals S.A. Vaccine
GB202302579D0 (en) 2023-02-23 2023-04-12 Glaxosmithkline Biologicals Sa Immunogenic composition
WO2025172892A1 (en) 2024-02-16 2025-08-21 Glaxosmithkline Biologicals Sa Modified proteins and methods

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AU2638595A (en) * 1994-05-16 1995-12-05 Uab Research Foundation, The (streptococcus pneumoniae) capsular polysaccharide genes and flanking regions
US7018637B2 (en) * 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
US7541043B2 (en) 2002-01-16 2009-06-02 The United States Of America As Represented By The Department Of Health And Human Services Vaccine for protection against Shigella sonnei disease
DK1481057T3 (da) 2002-03-07 2006-05-15 Eidgenoess Tech Hochschule System og fremgangsmåde til fremstilling af rekombinante glycosylerede proteiner i en prokaryot vært
ES2535084T3 (es) 2005-05-11 2015-05-05 Eth Zurich Proteínas N-glicosiladas recombinantes procedentes de células procariotas
SI2257307T1 (sl) 2008-02-20 2018-09-28 Glaxosmithkline Biologicals S.A. Biokonjugati, izdelani iz rekombinantnih N-glikoziliranih proteinov iz prokariontskih celic
WO2010110931A2 (en) 2009-03-23 2010-09-30 The Brigham And Women's Hospital, Inc. Glycoconjugate vaccines
JP2012533285A (ja) 2009-07-17 2012-12-27 オーシャン ハーベスト テクノロジー (カナダ) インコーポレイテッド 魚用飼料中の合成添加物を置換する、天然かつ持続可能な海藻配合物
WO2011138361A1 (en) 2010-05-06 2011-11-10 Glycovaxyn Capsular gram-positive bacteria bioconjugate vaccines
KR20150068998A (ko) * 2012-10-12 2015-06-22 글리코박신 아게 숙주 세포 변형 방법

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