JP2016540749A - グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用 - Google Patents

グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用 Download PDF

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JP2016540749A
JP2016540749A JP2016530898A JP2016530898A JP2016540749A JP 2016540749 A JP2016540749 A JP 2016540749A JP 2016530898 A JP2016530898 A JP 2016530898A JP 2016530898 A JP2016530898 A JP 2016530898A JP 2016540749 A JP2016540749 A JP 2016540749A
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eosinophilic
general formula
compound
pharmaceutically acceptable
syndrome
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JP2016540749A5 (OSRAM
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ネボルシン，ウラジミール・エヴゲニエヴィチ
クロモワ，タチアナ・アレクサンドロフナ
リドコフスカヤ，アナスタシア・ウラジミロフナ
チュチャリン，アレクサンドル・グリゴリエヴィッチ
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オブシェストヴォ・ス・オグラニチェンノイ・オトヴェトストヴェンノストジュ・“ファームエンタープライジーズ”
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/45—Non condensed piperidines, e.g. piperocaine having oxo groups directly attached to the heterocyclic ring, e.g. cycloheximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
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    • A61P19/00—Drugs for skeletal disorders
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    • A—HUMAN NECESSITIES
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/86—Oxygen atoms
    • C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide

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  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
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  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
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  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Physical Education & Sports Medicine (AREA)
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2016530898A 2013-11-14 2014-11-12 グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用 Ceased JP2016540749A (ja)

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RU2013150861 2013-11-14
RU2013150861/15A RU2552929C1 (ru) 2013-11-14 2013-11-14 Фармацевтическая композиция, содержащая производные глутаримидов, и их применение для лечения эозинофильных заболеваний
PCT/RU2014/000855 WO2015072893A1 (ru) 2013-11-14 2014-11-12 Фармацевтическая композиция, содержащая производные глутаримидов, и их применение для лечения эозинофильных заболеваний

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JP2018203599A Division JP6589251B2 (ja) 2013-11-14 2018-10-30 グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用

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JP2016540749A true JP2016540749A (ja) 2016-12-28
JP2016540749A5 JP2016540749A5 (OSRAM) 2017-12-07

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JP2016530898A Ceased JP2016540749A (ja) 2013-11-14 2014-11-12 グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用
JP2018203599A Active JP6589251B2 (ja) 2013-11-14 2018-10-30 グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用
JP2019151253A Expired - Fee Related JP6758677B2 (ja) 2013-11-14 2019-08-21 グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用
JP2019151258A Ceased JP2020002152A (ja) 2013-11-14 2019-08-21 グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用

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JP2019151253A Expired - Fee Related JP6758677B2 (ja) 2013-11-14 2019-08-21 グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用
JP2019151258A Ceased JP2020002152A (ja) 2013-11-14 2019-08-21 グルタルイミド誘導体を含む医薬組成物、及び好酸球性疾患を処置するためのその適用

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US (2) US9949962B2 (OSRAM)
EP (2) EP3466425B1 (OSRAM)
JP (4) JP2016540749A (OSRAM)
KR (2) KR102312294B1 (OSRAM)
CN (2) CN110200968A (OSRAM)
AU (2) AU2014349246C1 (OSRAM)
BR (1) BR112016010515B1 (OSRAM)
CA (1) CA2930231C (OSRAM)
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DK (1) DK3069720T3 (OSRAM)
EA (4) EA032940B1 (OSRAM)
ES (2) ES2759530T3 (OSRAM)
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IL (2) IL245429B (OSRAM)
LT (1) LT3069720T (OSRAM)
MX (2) MX386887B (OSRAM)
PL (2) PL3466425T3 (OSRAM)
PT (1) PT3069720T (OSRAM)
RU (1) RU2552929C1 (OSRAM)
SG (1) SG10201900504XA (OSRAM)
SI (1) SI3069720T1 (OSRAM)
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WO (1) WO2015072893A1 (OSRAM)

Cited By (2)

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JP2016516766A (ja) * 2013-04-12 2016-06-09 オブシェストヴォ・ス・オグラニチェンノイ・オトヴェトストヴェンノストジュ・“ファームエンタープライジーズ” グルタルイミド誘導体、その使用、それに基づいた医薬組成物及びグルタルイミド誘導体を製造するための方法
JP2022508167A (ja) * 2018-11-23 2022-01-19 “ケミミューン セラピューティクス” リミテッド ライアビリティー カンパニー ステロイド耐性の克服および異常なインターフェロンガンマシグナル伝達に関連する疾患の治療のためのグルタルイミド誘導体の使用

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TWI634900B (zh) 2013-07-11 2018-09-11 再生元醫藥公司 藉由投與ｉｌ－４ｒ抑制劑治療嗜酸性食道炎的方法
WO2015130975A1 (en) 2014-02-28 2015-09-03 Regeneron Pharmaceuticals, Inc. Methods for treating skin infection by administering an il-4r antagonist
EP4442323A3 (en) 2016-09-01 2025-01-01 Regeneron Pharmaceuticals, Inc. Methods for preventing or treating allergy by administering an il-4r antagonist
CN106539792B (zh) * 2016-11-07 2017-08-25 王晓旭 一种治疗高血脂症的药物
EA039391B1 (ru) * 2017-09-07 2022-01-21 Общество С Ограниченной Ответственностью "Хемиммьюн Терапьютикс" Применение производного глутаримида для лечения заболеваний, связанных с аберрантной активностью цитокинов
PH12021552123A1 (en) 2019-03-21 2022-08-22 Regeneron Pharma Combination of il-4/il-13 pathway inhibitors and plasma cell ablation for treating allergy
US11504426B2 (en) 2019-08-05 2022-11-22 Regeneron Pharmaceuticals, Inc. Methods for treating allergy and enhancing allergen-specific immunotherapy by administering an IL-4R antagonist
AU2020326713A1 (en) 2019-08-05 2022-02-17 Regeneron Pharmaceuticals, Inc. Methods for treating atopic dermatitis by administering an il-4r antagonist
EP4132571B1 (en) * 2020-04-07 2025-10-29 Hofseth Biocare ASA Salmonid oil compositions for use in the treatment of eosinophilic related inflammatory and respiratory conditions
BR112022026356A2 (pt) * 2020-06-26 2023-01-17 Valenta Intellekt Ltd Uso de um derivado de glutarimida para tratar doenças associadas à atividade aberrante da interleucina-6
WO2023113650A1 (ru) * 2021-12-15 2023-06-22 Владимир Евгеньевич НЕБОЛЬСИН Фармацевтическая композиция 1-[2-(1-метилимидазол-4-ил)-этил]пергидроазин-2,6-дион для терапии заболеваний верхних дыхательных путей

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016516766A (ja) * 2013-04-12 2016-06-09 オブシェストヴォ・ス・オグラニチェンノイ・オトヴェトストヴェンノストジュ・“ファームエンタープライジーズ” グルタルイミド誘導体、その使用、それに基づいた医薬組成物及びグルタルイミド誘導体を製造するための方法
JP2022508167A (ja) * 2018-11-23 2022-01-19 “ケミミューン セラピューティクス” リミテッド ライアビリティー カンパニー ステロイド耐性の克服および異常なインターフェロンガンマシグナル伝達に関連する疾患の治療のためのグルタルイミド誘導体の使用
JP2023015333A (ja) * 2018-11-23 2023-01-31 “ケミミューン セラピューティクス” リミテッド ライアビリティー カンパニー ステロイド耐性の克服および異常なインターフェロンガンマシグナル伝達に関連する疾患の治療のためのグルタルイミド誘導体の使用
JP7518997B2 (ja) 2018-11-23 2024-07-19 “ケミミューン セラピューティクス” リミテッド ライアビリティー カンパニー ステロイド耐性の克服および異常なインターフェロンガンマシグナル伝達に関連する疾患の治療のためのグルタルイミド誘導体の使用

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