JP2016539949A5 - - Google Patents
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- Publication number
- JP2016539949A5 JP2016539949A5 JP2016535014A JP2016535014A JP2016539949A5 JP 2016539949 A5 JP2016539949 A5 JP 2016539949A5 JP 2016535014 A JP2016535014 A JP 2016535014A JP 2016535014 A JP2016535014 A JP 2016535014A JP 2016539949 A5 JP2016539949 A5 JP 2016539949A5
- Authority
- JP
- Japan
- Prior art keywords
- type
- adverse effects
- gastrointestinal tract
- symptoms
- trichothecene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229930013292 trichothecene Natural products 0.000 claims 28
- 238000000034 method Methods 0.000 claims 21
- 230000002411 adverse Effects 0.000 claims 18
- 230000000694 effects Effects 0.000 claims 18
- LZAJKCZTKKKZNT-PMNGPLLRSA-N trichothecene Chemical compound C12([C@@]3(CC[C@H]2OC2C=C(CCC23C)C)C)CO1 LZAJKCZTKKKZNT-PMNGPLLRSA-N 0.000 claims 17
- 231100000678 Mycotoxin Toxicity 0.000 claims 15
- 210000001035 gastrointestinal tract Anatomy 0.000 claims 15
- 239000002636 mycotoxin Substances 0.000 claims 15
- 239000003463 adsorbent Substances 0.000 claims 14
- 231100000572 poisoning Toxicity 0.000 claims 14
- 230000000607 poisoning effect Effects 0.000 claims 14
- 208000024891 symptom Diseases 0.000 claims 14
- 150000003327 trichothecene derivatives Chemical class 0.000 claims 11
- 229910000323 aluminium silicate Inorganic materials 0.000 claims 8
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims 8
- 241001465754 Metazoa Species 0.000 claims 5
- 239000000654 additive Substances 0.000 claims 5
- 238000005341 cation exchange Methods 0.000 claims 5
- 230000002496 gastric effect Effects 0.000 claims 5
- 230000000996 additive effect Effects 0.000 claims 4
- 229930002954 deoxynivalenol Natural products 0.000 claims 4
- LINOMUASTDIRTM-QGRHZQQGSA-N deoxynivalenol Chemical compound C([C@@]12[C@@]3(C[C@@H](O)[C@H]1O[C@@H]1C=C(C([C@@H](O)[C@@]13CO)=O)C)C)O2 LINOMUASTDIRTM-QGRHZQQGSA-N 0.000 claims 4
- 239000000463 material Substances 0.000 claims 4
- LINOMUASTDIRTM-UHFFFAOYSA-N vomitoxin hydrate Natural products OCC12C(O)C(=O)C(C)=CC1OC1C(O)CC2(C)C11CO1 LINOMUASTDIRTM-UHFFFAOYSA-N 0.000 claims 4
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- ADFIQZBYNGPCGY-HTJQZXIKSA-N 3-acetyldeoxynivalenol Chemical compound C([C@]12[C@]3(C)C[C@H]([C@H]2O[C@H]2[C@@]3([C@H](O)C(=O)C(C)=C2)CO)OC(=O)C)O1 ADFIQZBYNGPCGY-HTJQZXIKSA-N 0.000 claims 2
- IDGRYIRJIFKTAN-UHFFFAOYSA-N 3-acetyldeoxynivalenol Natural products CC(=O)OCC12C(O)C(=O)C(C)=CC1OC1C(O)CC2(C)C11CO1 IDGRYIRJIFKTAN-UHFFFAOYSA-N 0.000 claims 2
- ADFIQZBYNGPCGY-UHFFFAOYSA-N Acetyldeoxynivalenol Natural products C1=C(C)C(=O)C(O)C2(CO)C1OC1C(OC(=O)C)CC2(C)C21CO2 ADFIQZBYNGPCGY-UHFFFAOYSA-N 0.000 claims 2
- 206010012735 Diarrhoea Diseases 0.000 claims 2
- XGCUCFKWVIWWNW-UHFFFAOYSA-N Fusarenone X Natural products CC(=O)OC1C(O)C2OC3C=C(C)C(=O)C(O)C3(CO)C1(C)C21CO1 XGCUCFKWVIWWNW-UHFFFAOYSA-N 0.000 claims 2
- PNKLMTPXERFKEN-MLXHEQMXSA-N HT-2 toxin Chemical compound C([C@@]12[C@]3(C)[C@H](O)[C@@H](O)[C@H]1O[C@H]1[C@]3(COC(C)=O)C[C@@H](C(=C1)C)OC(=O)CC(C)C)O2 PNKLMTPXERFKEN-MLXHEQMXSA-N 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- TVZHDVCTOCZDNE-UHFFFAOYSA-N Neosolaniol Natural products CC(=O)OCC12CC(O)C(C)=CC1OC1C(O)C(OC(C)=O)C2(C)C11CO1 TVZHDVCTOCZDNE-UHFFFAOYSA-N 0.000 claims 2
- ITCSWEBPTQLQKN-UHFFFAOYSA-N Nivalenol Natural products CC1=CC2OC3C(O)C(O)C(C2(CO)CC1=O)C34CO4 ITCSWEBPTQLQKN-UHFFFAOYSA-N 0.000 claims 2
- UKOTXHQERFPCBU-YQPARWETSA-N Nivalenol Chemical compound C([C@]12[C@@]3([C@H](O)[C@@H](O)[C@H]1O[C@@H]1C=C(C([C@@H](O)[C@@]13CO)=O)C)C)O2 UKOTXHQERFPCBU-YQPARWETSA-N 0.000 claims 2
- BXFOFFBJRFZBQZ-QYWOHJEZSA-N T-2 toxin Chemical compound C([C@@]12[C@]3(C)[C@H](OC(C)=O)[C@@H](O)[C@H]1O[C@H]1[C@]3(COC(C)=O)C[C@@H](C(=C1)C)OC(=O)CC(C)C)O2 BXFOFFBJRFZBQZ-QYWOHJEZSA-N 0.000 claims 2
- 206010047700 Vomiting Diseases 0.000 claims 2
- 239000012736 aqueous medium Substances 0.000 claims 2
- 230000000740 bleeding effect Effects 0.000 claims 2
- XGCUCFKWVIWWNW-CAYGJDLQSA-N fusarenone x Chemical compound C([C@@]12[C@@]3(C)[C@@]4(CO)[C@H](O)C(=O)C(C)=C[C@H]4O[C@@H]1[C@H](O)[C@H]3OC(=O)C)O2 XGCUCFKWVIWWNW-CAYGJDLQSA-N 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims 2
- 230000017074 necrotic cell death Effects 0.000 claims 2
- TVZHDVCTOCZDNE-WVJYZQHISA-N neosolaniol Chemical compound C([C@@]12[C@]3(C)[C@H](OC(C)=O)[C@@H](O)[C@H]1O[C@@H]1C=C(C)[C@@H](O)C[C@@]13COC(=O)C)O2 TVZHDVCTOCZDNE-WVJYZQHISA-N 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000008673 vomiting Effects 0.000 claims 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical group [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 claims 1
- 229910052794 bromium Inorganic materials 0.000 claims 1
- 125000001246 bromo group Chemical group Br* 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229910052801 chlorine Chemical group 0.000 claims 1
- 239000000460 chlorine Chemical group 0.000 claims 1
- UHZZMRAGKVHANO-UHFFFAOYSA-M chlormequat chloride Chemical compound [Cl-].C[N+](C)(C)CCCl UHZZMRAGKVHANO-UHFFFAOYSA-M 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- 230000008030 elimination Effects 0.000 claims 1
- 238000003379 elimination reaction Methods 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 229910052736 halogen Inorganic materials 0.000 claims 1
- 150000002367 halogens Chemical group 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 229910052615 phyllosilicate Inorganic materials 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 238000001179 sorption measurement Methods 0.000 claims 1
- 238000003756 stirring Methods 0.000 claims 1
- 229910052645 tectosilicate Inorganic materials 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 0 *c1ccc(C=*)cc1 Chemical compound *c1ccc(C=*)cc1 0.000 description 2
- BFFUBOLNTYQJJE-UHFFFAOYSA-N CCCCCCCCCc(cc1)ccc1OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(C)(C)Cc1ccccc1 Chemical compound CCCCCCCCCc(cc1)ccc1OCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(C)(C)Cc1ccccc1 BFFUBOLNTYQJJE-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MXMX/A/2013/013788 | 2013-11-25 | ||
| MX2013013788A MX338482B (es) | 2013-11-25 | 2013-11-25 | Absorbente de micotoxinas y su uso en alimentos balanceados para animales. |
| PCT/IB2014/066246 WO2015075686A1 (es) | 2013-11-25 | 2014-11-21 | Absorbente de micotoxinas y su uso en alimentos balanceados para animales |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539949A JP2016539949A (ja) | 2016-12-22 |
| JP2016539949A5 true JP2016539949A5 (https=) | 2017-12-07 |
| JP6387097B2 JP6387097B2 (ja) | 2018-09-05 |
Family
ID=53179054
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016535014A Expired - Fee Related JP6387097B2 (ja) | 2013-11-25 | 2014-11-21 | マイコトキシン吸着剤及びその動物用配合飼料における使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20160287617A1 (https=) |
| EP (1) | EP3075260B1 (https=) |
| JP (1) | JP6387097B2 (https=) |
| CN (1) | CN105792665B (https=) |
| CA (1) | CA2930547C (https=) |
| CL (1) | CL2016001264A1 (https=) |
| ES (1) | ES2761568T3 (https=) |
| MX (1) | MX338482B (https=) |
| PE (1) | PE20160684A1 (https=) |
| RS (1) | RS59791B1 (https=) |
| WO (1) | WO2015075686A1 (https=) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX354792B (es) * | 2016-06-22 | 2018-03-21 | Nutek S A De C V | Adsorbente de micotoxinas con base en un derivado de betaina para alimentos balanceados de animales. |
| EP3430913B1 (en) | 2017-07-20 | 2020-12-02 | Tolsa, S.A. | Composition for binding mycotoxins and its use |
| JP7384455B2 (ja) * | 2018-08-20 | 2023-11-21 | テキサス・エイ・アンド・エム・ユニバーシティ | 突発、自然災害および緊急事態後の摂取可能環境毒素への急性曝露を軽減するために使用される食用腸収着剤 |
| CN109364885B (zh) * | 2018-11-24 | 2021-03-12 | 烟台大学 | 羧甲基纤维素钠-胶原-蒙脱土复合黄曲霉菌吸附材料的制备方法 |
| CN109939648B (zh) * | 2019-03-15 | 2023-04-14 | 上海岩康生物科技有限公司 | 一种复合型广谱性霉菌毒素吸附剂及其制备方法 |
| CN110776568B (zh) * | 2019-11-15 | 2023-04-18 | 中国农业科学院油料作物研究所 | 净化伏马毒素b1、蛇形毒素、t-2毒素、玉米赤霉烯酮、呕吐毒素复合亲和柱 |
| CN111298775B (zh) * | 2020-03-03 | 2022-04-26 | 武汉轻工大学 | 一种甲壳素磁性微球吸附剂及其制备方法和应用 |
| DE102020115832B3 (de) | 2020-06-16 | 2021-12-16 | AdFiS products GmbH | Mykotoxin-Adsorber auf Basis von Aktivkohle |
| MX2023013426A (es) * | 2021-05-17 | 2023-12-12 | Nutek S A De C V | Uso de un adsorbente de fumonisina b1 y zearalenona en alimentos balanceados para animales. |
| CN113713777B (zh) * | 2021-09-13 | 2024-01-09 | 湖南农业大学 | 蛋壳粉呕吐毒素吸附剂的制备方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH443774A (de) * | 1963-05-30 | 1967-09-15 | Ciba Geigy | Mittel zur Bekämpfung phytopathogener Mikroorganismen |
| DE3126522A1 (de) * | 1981-07-04 | 1983-01-20 | Basf Ag, 6700 Ludwigshafen | Quaternaere ammoniumsalze und verfahren zu ihrer herstellung |
| DE3810004A1 (de) | 1988-03-24 | 1989-10-05 | Siegfried Dr Moser | Verwendung von bentoniten zur mykotoxinbindung |
| BR9105978A (pt) | 1990-03-07 | 1992-11-17 | Engelhard Corp | Aditivo de forragem particulado,e composicao de forragem |
| DE19900813A1 (de) | 1999-01-12 | 2000-07-13 | Sued Chemie Ag | Mykotoxin-Adsorbens |
| MXPA00007077A (es) * | 2000-07-19 | 2003-09-08 | Nutek S A De C V | Proceso para preparar organoaluminosilicatos y su uso en alimentos balanceados para animales. |
| DE10056634A1 (de) | 2000-11-15 | 2002-05-29 | Sued Chemie Ag | Verwendung Aktivierter Schichtsilicate zur Mykotoxinadsorption |
| HRPK20020706B3 (en) | 2000-12-28 | 2005-04-30 | Institut Za Tehnologiju Nuklearnih I Drugih Minera | Organomineral adsorbent of mycotoxin as an animal feed additive, procedure for production and application |
| EP1363854B1 (en) * | 2001-02-15 | 2009-04-22 | PATENT CO., preduzece za proizvodnju, usluge i promet d.o.o. Misicevo | Tribochemical process for obtaining organozeolite adsorbent of mycotoxins |
| JP2008544835A (ja) | 2005-05-10 | 2008-12-11 | ジュート−ヒェミー アクチェンゲゼルシャフト | マイコトキシン吸着のためのステべンサイトの使用 |
| JP4295761B2 (ja) * | 2005-12-27 | 2009-07-15 | 学校法人酪農学園 | マイコトキシン除去用飼料添加剤 |
| JP2009542656A (ja) * | 2006-06-27 | 2009-12-03 | ザ、テクサス、エイ、アンド、エム、ユーニヴァーサティ、システィム | 毒素の腸内収着および管理のための組成物および方法 |
| KR20090034506A (ko) * | 2007-10-04 | 2009-04-08 | 주식회사 카이로라이트 | 악취 및 ＶＯＣ'ｓ 제거기능을 갖는 친유성 실리케이트 및그 제조방법 |
| ES2392130T3 (es) | 2009-06-29 | 2012-12-04 | Adiveter S.L. | Adsorbente de micotoxinas |
| EP2289617A1 (en) | 2009-08-27 | 2011-03-02 | Süd-Chemie AG | Toxin adsorbent |
| EA201300220A1 (ru) | 2010-09-16 | 2013-10-30 | Тихомиров, Дмитрий Фёдорович | Составы и способы обезвреживания микотоксинов в пище и кормах и защиты растений от микробного заражения |
| US8858970B2 (en) * | 2011-01-13 | 2014-10-14 | Austin Research Labs Corp. | High load dispersions |
| CN102847509B (zh) * | 2012-04-17 | 2014-05-14 | 东北农业大学 | 一种饲料霉菌毒素吸附剂及其制备方法 |
-
2013
- 2013-11-25 MX MX2013013788A patent/MX338482B/es active IP Right Grant
-
2014
- 2014-11-21 ES ES14864455T patent/ES2761568T3/es active Active
- 2014-11-21 CN CN201480063868.4A patent/CN105792665B/zh not_active Expired - Fee Related
- 2014-11-21 US US15/037,661 patent/US20160287617A1/en not_active Abandoned
- 2014-11-21 WO PCT/IB2014/066246 patent/WO2015075686A1/es not_active Ceased
- 2014-11-21 CA CA2930547A patent/CA2930547C/en not_active Expired - Fee Related
- 2014-11-21 JP JP2016535014A patent/JP6387097B2/ja not_active Expired - Fee Related
- 2014-11-21 RS RS20191577A patent/RS59791B1/sr unknown
- 2014-11-21 PE PE2016000612A patent/PE20160684A1/es unknown
- 2014-11-21 EP EP14864455.2A patent/EP3075260B1/en not_active Not-in-force
-
2016
- 2016-05-24 CL CL2016001264A patent/CL2016001264A1/es unknown
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