JP2016539925A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016539925A5 JP2016539925A5 JP2016525584A JP2016525584A JP2016539925A5 JP 2016539925 A5 JP2016539925 A5 JP 2016539925A5 JP 2016525584 A JP2016525584 A JP 2016525584A JP 2016525584 A JP2016525584 A JP 2016525584A JP 2016539925 A5 JP2016539925 A5 JP 2016539925A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- citrullinated
- disorder
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361894042P | 2013-10-22 | 2013-10-22 | |
| US61/894,042 | 2013-10-22 | ||
| PCT/EP2014/072606 WO2015059168A1 (en) | 2013-10-22 | 2014-10-22 | Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of tlr4 ligands and other biomarkers |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018246722A Division JP2019048895A (ja) | 2013-10-22 | 2018-12-28 | Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016539925A JP2016539925A (ja) | 2016-12-22 |
| JP2016539925A5 true JP2016539925A5 (https=) | 2017-11-30 |
Family
ID=51866128
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016525584A Pending JP2016539925A (ja) | 2013-10-22 | 2014-10-22 | Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物 |
| JP2018246722A Withdrawn JP2019048895A (ja) | 2013-10-22 | 2018-12-28 | Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物 |
| JP2020177986A Pending JP2021006592A (ja) | 2013-10-22 | 2020-10-23 | Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物 |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018246722A Withdrawn JP2019048895A (ja) | 2013-10-22 | 2018-12-28 | Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物 |
| JP2020177986A Pending JP2021006592A (ja) | 2013-10-22 | 2020-10-23 | Tlr4リガンドまたは他のバイオマーカーのレベルが上昇した患者における障害の診断および処置を行うための方法および組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9688769B2 (https=) |
| EP (1) | EP3060250A1 (https=) |
| JP (3) | JP2016539925A (https=) |
| CN (1) | CN105899231A (https=) |
| AU (2) | AU2014338991B2 (https=) |
| CA (1) | CA2928317A1 (https=) |
| WO (1) | WO2015059168A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2831117B1 (en) * | 2012-03-29 | 2017-11-01 | NovImmune SA | Anti-tlr4 antibodies and uses thereof |
| WO2015059168A1 (en) | 2013-10-22 | 2015-04-30 | Novimmune S.A. | Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of tlr4 ligands and other biomarkers |
| US20170038381A1 (en) * | 2015-08-06 | 2017-02-09 | Novimmune Sa | Methods and compositions for identifying patient populations for diagnosis and treatment of tlr4-dependent disorders |
| CN110073217A (zh) * | 2016-10-04 | 2019-07-30 | 豪夫迈·罗氏有限公司 | 用于鉴定合成分类器的系统和方法 |
| CA3052720A1 (en) | 2017-02-07 | 2018-08-16 | Orthogenics As | Biomarkers for diagnosing implant related risk of implant revision due to aseptic loosening |
| WO2020225549A1 (en) * | 2019-05-06 | 2020-11-12 | The Francis Crick Institute Limited | Method for preventing inflammation |
| WO2021119761A1 (en) * | 2019-12-20 | 2021-06-24 | Hudson Institute of Medical Research | Cxcl10 binding proteins and uses thereof |
| EP4138912A4 (en) * | 2020-04-20 | 2024-08-07 | Edesa Biotech Research Inc. | COMPOSITIONS AND METHODS FOR TREATING ACUTE RESPIRATORY DISTRESS SYNDROME |
| CN113358872B (zh) * | 2021-06-03 | 2022-10-21 | 中山大学肿瘤防治中心(中山大学附属肿瘤医院、中山大学肿瘤研究所) | 用于评估肿瘤免疫治疗疗效的标志物组及系统 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| EP1711531B9 (en) * | 2003-12-10 | 2012-07-25 | Novimmune SA | Neutralizing anti tlr4/md-2 antibodies and methods of use thereof |
| US7312320B2 (en) | 2003-12-10 | 2007-12-25 | Novimmune Sa | Neutralizing antibodies and methods of use thereof |
| US7674884B2 (en) * | 2003-12-10 | 2010-03-09 | Novimmune S.A. | Neutralizing antibodies and methods of use thereof |
| KR101380200B1 (ko) | 2004-08-12 | 2014-04-01 | 헬신 세라퓨틱스 (유.에스.) 인크. | 성장 호르몬 분비촉진제를 이용하여 위장관계의 운동성을촉진하는 방법 |
| AU2005325482B2 (en) * | 2004-12-10 | 2011-06-16 | Novimmune S.A. | Combining therapies targeting multiple toll-like receptors and use thereof |
| EP1919979B2 (en) | 2005-08-25 | 2017-03-29 | Creabilis Therapeutics S.P.A. | Polymer conjugates of k-252a and derivatives thereof |
| SI1919979T1 (sl) * | 2005-08-25 | 2014-02-28 | Creabilis Therapeutics S.P.A. | Polimerni konjugati K-252A in njihovi derivati |
| US20070148704A1 (en) * | 2005-10-06 | 2007-06-28 | Ursula Klause | Anti-CCPand antinuclear antibodies in diagnosis of rheumatoid arthritis |
| US7712333B2 (en) | 2006-03-29 | 2010-05-11 | Asahi Glass Company, Limited | Method for smoothing a surface of a glass substrate for a reflective mask blank used in EUV lithography |
| SI2173381T1 (sl) | 2007-05-14 | 2014-01-31 | Novimmune Sa | Fc receptor-vezavni polipeptidi z modificiranimi efektorskimi funkcijami |
| WO2009013848A1 (ja) | 2007-07-24 | 2009-01-29 | Panasonic Corporation | ニッケル水素電池用負極材料とその処理方法およびニッケル水素電池 |
| WO2009138494A2 (en) | 2008-05-15 | 2009-11-19 | Ablynx N.V. | Amino acid sequences directed against toll-like receptors and polypeptides comprising the same for the treatment of diseases related to toll-like receptors |
| US9140701B2 (en) * | 2009-08-18 | 2015-09-22 | The Board Of Trustees Of The Leland Stanford Junior University | Fibrinogen immune complexes to diagnose and guide therapy in rheumatoid arthritis |
| MX362591B (es) | 2010-11-05 | 2019-01-25 | Novartis Ag | Uso de antagonistas de il-17. |
| WO2012096917A1 (en) * | 2011-01-10 | 2012-07-19 | Novimmune S.A. | Anti-tlr4 antibodies and methods of use thereof |
| US20140378531A1 (en) * | 2012-02-01 | 2014-12-25 | New York University | Inhibition of pattern recognition receptors in pancreatic cancer treatment using tlr inhibitors |
| WO2015010791A2 (en) | 2013-07-24 | 2015-01-29 | Klareskog, Lars | Novel antibodies for the diagnosis and treatment of rheumatoid arthritis |
| WO2015059168A1 (en) | 2013-10-22 | 2015-04-30 | Novimmune S.A. | Methods and compositions for diagnosis and treatment of disorders in patients with elevated levels of tlr4 ligands and other biomarkers |
-
2014
- 2014-10-22 WO PCT/EP2014/072606 patent/WO2015059168A1/en not_active Ceased
- 2014-10-22 EP EP14793805.4A patent/EP3060250A1/en not_active Withdrawn
- 2014-10-22 US US14/520,904 patent/US9688769B2/en active Active
- 2014-10-22 AU AU2014338991A patent/AU2014338991B2/en not_active Ceased
- 2014-10-22 JP JP2016525584A patent/JP2016539925A/ja active Pending
- 2014-10-22 CA CA2928317A patent/CA2928317A1/en not_active Abandoned
- 2014-10-22 CN CN201480070143.8A patent/CN105899231A/zh active Pending
-
2017
- 2017-06-26 US US15/632,882 patent/US10556960B2/en active Active
-
2018
- 2018-12-28 JP JP2018246722A patent/JP2019048895A/ja not_active Withdrawn
-
2020
- 2020-09-11 AU AU2020230333A patent/AU2020230333A1/en not_active Abandoned
- 2020-10-23 JP JP2020177986A patent/JP2021006592A/ja active Pending
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2016539925A5 (https=) | ||
| Titcombe et al. | Pathogenic citrulline‐multispecific B cell receptor clades in rheumatoid arthritis | |
| JP2019048895A5 (https=) | ||
| ES2989669T3 (es) | Anticuerpos monoclonales inmunoestimuladores contra interleucina 2 humana | |
| Vaisman-Mentesh et al. | Molecular landscape of anti-drug antibodies reveals the mechanism of the immune response following treatment with TNFα antagonists | |
| Lindquist et al. | B cells and antibodies in Kawasaki disease | |
| JP2020536488A5 (https=) | ||
| RU2017107773A (ru) | Антитела, специфичные к ммр9 | |
| Charles et al. | Somatic hypermutations confer rheumatoid factor activity in hepatitis C virus–associated mixed cryoglobulinemia | |
| JP2015533788A5 (https=) | ||
| JP2020522261A5 (https=) | ||
| Goh et al. | A novel human anti-interleukin-1β neutralizing monoclonal antibody showing in vivo efficacy | |
| Vergroesen et al. | N-glycosylation site analysis of citrullinated antigen-specific B-cell receptors indicates alternative selection pathways during autoreactive B-cell development | |
| JP2012012402A5 (https=) | ||
| Von Büdingen et al. | Clonally expanded plasma cells in the cerebrospinal fluid of patients with central nervous system autoimmune demyelination produce “oligoclonal bands” | |
| JP2012143232A5 (https=) | ||
| Pelzek et al. | Persistence of Disease‐Associated Anti–Citrullinated Protein Antibody–Expressing Memory B Cells in Rheumatoid Arthritis in Clinical Remission | |
| JP2021500916A5 (https=) | ||
| Hoxha et al. | The clinical relevance of early anti-adalimumab antibodies detection in rheumatoid arthritis, ankylosing spondylitis and psoriatic arthritis: a prospective multicentre study | |
| JP2014518883A5 (https=) | ||
| JP2013531655A5 (https=) | ||
| HK1219512A1 (zh) | 用於诊断和治疗炎性肠病的方法 | |
| WO2017213695A1 (en) | Compositions and methods relating to t peripheral helper cells in autoantibody-associated conditions | |
| JP2018507254A5 (https=) | ||
| Maurer et al. | Rituximab induces clonal expansion of IgG memory B-cells in patients with inflammatory central nervous system demyelination |