JP2016539100A5 - - Google Patents
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- Publication number
- JP2016539100A5 JP2016539100A5 JP2016526933A JP2016526933A JP2016539100A5 JP 2016539100 A5 JP2016539100 A5 JP 2016539100A5 JP 2016526933 A JP2016526933 A JP 2016526933A JP 2016526933 A JP2016526933 A JP 2016526933A JP 2016539100 A5 JP2016539100 A5 JP 2016539100A5
- Authority
- JP
- Japan
- Prior art keywords
- substituted
- composition according
- unsubstituted
- composition
- amphiphilic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 15
- 239000003814 drug Substances 0.000 claims 6
- 229940079593 drug Drugs 0.000 claims 6
- -1 carbohydrate compound Chemical class 0.000 claims 5
- 125000000217 alkyl group Chemical group 0.000 claims 3
- 229920001661 Chitosan Polymers 0.000 claims 2
- ROHFNLRQFUQHCH-YFKPBYRVSA-N L-leucine Chemical compound CC(C)C[C@H](N)C(O)=O ROHFNLRQFUQHCH-YFKPBYRVSA-N 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 125000002009 alkene group Chemical group 0.000 claims 2
- 150000001875 compounds Chemical class 0.000 claims 2
- 125000001033 ether group Chemical group 0.000 claims 2
- 229910052739 hydrogen Inorganic materials 0.000 claims 2
- 239000001257 hydrogen Substances 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- BXCRLBBIZJSWNS-UHFFFAOYSA-N 2-hydroxyethyl hexadecanoate Chemical compound CCCCCCCCCCCCCCCC(=O)OCCO BXCRLBBIZJSWNS-UHFFFAOYSA-N 0.000 claims 1
- 208000003174 Brain Neoplasms Diseases 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 claims 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 1
- ROHFNLRQFUQHCH-UHFFFAOYSA-N Leucine Natural products CC(C)CC(N)C(O)=O ROHFNLRQFUQHCH-UHFFFAOYSA-N 0.000 claims 1
- 208000008589 Obesity Diseases 0.000 claims 1
- 208000027520 Somatoform disease Diseases 0.000 claims 1
- 239000008186 active pharmaceutical agent Substances 0.000 claims 1
- 125000003368 amide group Chemical group 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 239000012736 aqueous medium Substances 0.000 claims 1
- 210000004556 brain Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940088679 drug related substance Drugs 0.000 claims 1
- 150000002431 hydrogen Chemical class 0.000 claims 1
- 125000001165 hydrophobic group Chemical group 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 230000000626 neurodegenerative effect Effects 0.000 claims 1
- 235000020824 obesity Nutrition 0.000 claims 1
- 208000027753 pain disease Diseases 0.000 claims 1
- 239000002245 particle Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 208000020016 psychiatric disease Diseases 0.000 claims 1
- 125000001453 quaternary ammonium group Chemical group 0.000 claims 1
- 201000000980 schizophrenia Diseases 0.000 claims 1
- 238000001338 self-assembly Methods 0.000 claims 1
- 208000019116 sleep disease Diseases 0.000 claims 1
- 125000000547 substituted alkyl group Chemical group 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB1319437.8A GB201319437D0 (en) | 2013-11-04 | 2013-11-04 | Delivery of drugs |
| GB1319437.8 | 2013-11-04 | ||
| PCT/GB2014/053254 WO2015063510A1 (en) | 2013-11-04 | 2014-11-03 | Delivery of drugs |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016539100A JP2016539100A (ja) | 2016-12-15 |
| JP2016539100A5 true JP2016539100A5 (enExample) | 2017-11-24 |
| JP6486349B2 JP6486349B2 (ja) | 2019-03-20 |
Family
ID=49767616
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016526933A Active JP6486349B2 (ja) | 2013-11-04 | 2014-11-03 | 薬物の送達 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10213474B2 (enExample) |
| EP (1) | EP3065779B1 (enExample) |
| JP (1) | JP6486349B2 (enExample) |
| CA (1) | CA2928697C (enExample) |
| GB (1) | GB201319437D0 (enExample) |
| WO (1) | WO2015063510A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB202007703D0 (en) * | 2020-05-22 | 2020-07-08 | Nanomerics Ltd | Amphiphilic carbohydrate compounds |
| CA3192515A1 (en) * | 2020-08-24 | 2022-03-03 | Nanomerics Limited | Viral inhibitors |
| US20250009676A1 (en) * | 2021-10-06 | 2025-01-09 | Purdue Pharma L.P. | Compositions and methods for levodopa delivery |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5763393A (en) * | 1996-05-17 | 1998-06-09 | Neurotherapeutics L.P. | Neuroactive peptides |
| GB0221941D0 (en) | 2002-09-20 | 2002-10-30 | Univ Strathclyde | Polysoaps |
| GB0315632D0 (en) * | 2003-07-04 | 2003-08-13 | West Pharm Serv Drug Res Ltd | Pharmaceutical formulations |
| US8187570B1 (en) * | 2005-01-04 | 2012-05-29 | Gp Medical, Inc. | Nanoparticles for protein drug delivery |
| GB0615834D0 (en) | 2006-08-09 | 2006-09-20 | Univ Glasgow | Polymeric micellar clusters and their uses in formulating drugs |
| JP2009252275A (ja) * | 2008-04-03 | 2009-10-29 | Nec Electronics Corp | 半導体記憶装置 |
| TWI437007B (zh) * | 2008-07-24 | 2014-05-11 | Food Industry Res & Dev Inst | 於水相中製備幾丁聚醣奈米顆粒之方法 |
| GB0903559D0 (en) * | 2009-03-02 | 2009-04-08 | Univ London Pharmacy | Oral delivery of hydrophilic drugs to the brain |
| WO2012039979A2 (en) * | 2010-09-10 | 2012-03-29 | The Johns Hopkins University | Rapid diffusion of large polymeric nanoparticles in the mammalian brain |
| EP3269372B1 (en) * | 2012-01-19 | 2019-06-12 | Hybrid Medical, LLC | Topical therapeutic formulations |
-
2013
- 2013-11-04 GB GBGB1319437.8A patent/GB201319437D0/en not_active Ceased
-
2014
- 2014-11-03 US US15/034,321 patent/US10213474B2/en active Active
- 2014-11-03 WO PCT/GB2014/053254 patent/WO2015063510A1/en not_active Ceased
- 2014-11-03 CA CA2928697A patent/CA2928697C/en active Active
- 2014-11-03 EP EP14802477.1A patent/EP3065779B1/en active Active
- 2014-11-03 JP JP2016526933A patent/JP6486349B2/ja active Active
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