JP2016538545A - 肝臓癌の診断及び予後判定のための材料及び方法 - Google Patents

肝臓癌の診断及び予後判定のための材料及び方法 Download PDF

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JP2016538545A
JP2016538545A JP2016530873A JP2016530873A JP2016538545A JP 2016538545 A JP2016538545 A JP 2016538545A JP 2016530873 A JP2016530873 A JP 2016530873A JP 2016530873 A JP2016530873 A JP 2016530873A JP 2016538545 A JP2016538545 A JP 2016538545A
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liver
protein
cell
marker
marker proteins
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JP2016538545A5 (enExample
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アンドリュー ワード マルコルム
アンドリュー ワード マルコルム
ヒューゴ ピケ イアン
ヒューゴ ピケ イアン
ジェームス ブリットン デビッド
ジェームス ブリットン デビッド
ミトラ ビクラム
ミトラ ビクラム
デビッド ヒートン ニゲル
デビッド ヒートン ニゲル
ゼン ヨー
ゼン ヨー
クアグリア アルベルト
クアグリア アルベルト
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Proteome Sciences PLC
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Electrophoretics Ltd
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57423—Specifically defined cancers of lung
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis

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  • Engineering & Computer Science (AREA)
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  • Bioinformatics & Computational Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
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  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
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JP2016530873A 2013-11-13 2014-11-13 肝臓癌の診断及び予後判定のための材料及び方法 Pending JP2016538545A (ja)

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Application Number Priority Date Filing Date Title
GB1320061.3 2013-11-13
GBGB1320061.3A GB201320061D0 (en) 2013-11-13 2013-11-13 Materials nad methods for diagnosis and prognosis of liver cancer
PCT/GB2014/053368 WO2015071669A2 (en) 2013-11-13 2014-11-13 Materials and methods for diagnosis and prognosis of liver cancer

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JP2016538545A true JP2016538545A (ja) 2016-12-08
JP2016538545A5 JP2016538545A5 (enExample) 2018-04-12

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US (1) US20160320395A1 (enExample)
EP (1) EP3069142A2 (enExample)
JP (1) JP2016538545A (enExample)
CA (1) CA2928510A1 (enExample)
GB (1) GB201320061D0 (enExample)
WO (1) WO2015071669A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
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JP2019537108A (ja) * 2016-10-05 2019-12-19 ユーイーエー エンタープライジズ リミテッド 癌の分類および予後
JP2021173529A (ja) * 2020-04-17 2021-11-01 合同会社Ｈ．Ｕ．グループ中央研究所 胆管がんのバイオマーカー

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CN105288659B (zh) * 2015-06-01 2019-07-26 北京泱深生物信息技术有限公司 Tenm1基因及其表达产物在诊治乳头状腺癌的应用
KR101750411B1 (ko) * 2015-07-10 2017-06-27 한국생명공학연구원 엑소좀 단백질 eif3a 특이반응 오토항체검출용 항원 조성물 및 이를 이용한 간암진단법
FR3048780B1 (fr) * 2016-03-11 2020-11-06 Commissariat Energie Atomique Procede de diagnostic in vitro d'atteintes hepatiques
EP3403100B1 (fr) * 2016-01-15 2020-03-11 Commissariat à l'Énergie Atomique et aux Énergies Alternatives Procédé de diagnostic in vitro d'atteintes hépatiques
GB201619954D0 (en) * 2016-11-25 2017-01-11 Oncimmune Ltd Antibody assay
KR102712656B1 (ko) 2017-01-23 2024-10-04 리제너론 파마슈티칼스 인코포레이티드 Hsd17b13 변종 및 이것의 용도
CN115266962B (zh) * 2017-03-31 2024-05-31 北京谷海天目生物医学科技有限公司 蛋白标志物在制备弥漫型胃癌分子分型的产品中的应用及弥漫型胃癌分子分型的分类器
US11479802B2 (en) 2017-04-11 2022-10-25 Regeneron Pharmaceuticals, Inc. Assays for screening activity of modulators of members of the hydroxy steroid (17-beta) dehydrogenase (HSD17B) family
WO2018189215A1 (en) * 2017-04-12 2018-10-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Method for predicting the survival time of a patient suffering from hepatocellular carcinoma
AU2018348195B2 (en) 2017-10-11 2025-05-15 Regeneron Pharmaceuticals, Inc. Inhibition of HSD17B13 in the treatment of liver disease in patients expressing the PNPLA3 I148M variation
CN109596829A (zh) * 2017-12-07 2019-04-09 南京医科大学 一种肝癌标志蛋白及其检测方法
WO2019115679A1 (en) * 2017-12-13 2019-06-20 Fundació Institut D'investigació En Ciències De La Salut Germans Trias I Pujol A signature to assess prognosis and therapeutic regimen in liver cancer
BR112020018758A2 (pt) 2018-03-21 2021-01-26 Regeneron Pharmaceuticals, Inc. agente de ácido ribonucleico de fita dupla, célula, vetor, composição farmacêutica, e, métodos para inibição da expressão de 17¿-hidroxiesteroide desidrogenases tipo 13, para tratamento de um indivíduo, para prevenção de um sintoma em um indivíduo, para redução do risco de desenvolver doença hepática crônica, para inibição da progressão de esteatose, para inibição do acúmulo de gotículas de lipídios
US20220244263A1 (en) * 2019-05-28 2022-08-04 The Regents Of The University Of California Methods for treating small cell neuroendocrine and related cancers
CA3166923A1 (en) * 2020-02-10 2021-08-19 Somalogic Operating Co., Inc. Nonalcoholic steatohepatitis (nash) biomarkers and uses thereof
EP4115181A1 (en) * 2020-03-02 2023-01-11 Université de Strasbourg Method for diagnosis and/or prognosis of liver disease progression and risk of hepatocellular carcinoma and discovery of therapeutic compounds and targets to treat liver disease and cancer
CN111748624B (zh) * 2020-06-08 2022-11-04 郑州大学第一附属医院 用于预测肝癌是否复发的生物标志物
CN111748623B (zh) * 2020-06-08 2022-11-04 郑州大学第一附属医院 肝癌患者是否复发的预测标志物及试剂盒
CN112961916B (zh) * 2020-11-10 2024-03-12 上海市肿瘤研究所 Akr1c3作为肝癌预后的生物学标志物及其应用
CN112908470B (zh) * 2021-02-08 2023-10-03 深圳市人民医院 一种基于rna结合蛋白基因的肝细胞癌预后评分系统及其应用
CN113462777A (zh) * 2021-06-28 2021-10-01 武汉大学 P4hb在制备肝细胞癌早期诊断试剂盒及制备或筛选抗肝癌药物中的应用
CN114814001B (zh) * 2022-03-31 2023-02-21 武汉大学 用于制备肝癌检测试剂的新型代谢标志物及其应用
CN115754290A (zh) * 2022-09-26 2023-03-07 浙江大学 一种用于检测早期肝癌的试剂盒
CN115807089B (zh) * 2022-11-14 2024-09-13 石河子大学 肝细胞肝癌预后生物标志物及应用
CN116338189B (zh) * 2023-01-16 2025-08-22 浙江大学医学院附属第一医院 具有蛋白激酶功能的肿瘤标志物ckb在制备肿瘤诊断产品中的应用
CN116386715A (zh) * 2023-03-09 2023-07-04 福建医科大学孟超肝胆医院 用于原发性肝细胞癌蛋白质组分子分型诊断的特征蛋白及其应用
CN117607438A (zh) * 2023-11-23 2024-02-27 浙江大学 一种肝细胞癌鉴别诊断和分化程度检测方法
CN119314683B (zh) * 2024-12-17 2025-02-25 吉林大学第一医院 一种用于肝移植术后预测系统

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Publication number Priority date Publication date Assignee Title
JP2019537108A (ja) * 2016-10-05 2019-12-19 ユーイーエー エンタープライジズ リミテッド 癌の分類および予後
JP2023003422A (ja) * 2016-10-05 2023-01-11 ユーイーエー エンタープライジズ リミテッド 癌の分類および予後
JP7539443B2 (ja) 2016-10-05 2024-08-23 ユーイーエー エンタープライジズ リミテッド 癌の分類および予後
JP2021173529A (ja) * 2020-04-17 2021-11-01 合同会社Ｈ．Ｕ．グループ中央研究所 胆管がんのバイオマーカー
JP7471898B2 (ja) 2020-04-17 2024-04-22 合同会社Ｈ．Ｕ．グループ中央研究所 胆管がんのバイオマーカー

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GB201320061D0 (en) 2013-12-25
US20160320395A1 (en) 2016-11-03
EP3069142A2 (en) 2016-09-21
CA2928510A1 (en) 2015-05-21
WO2015071669A2 (en) 2015-05-21
WO2015071669A3 (en) 2015-09-17

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