JP2016535266A5 - - Google Patents
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- Publication number
- JP2016535266A5 JP2016535266A5 JP2016527237A JP2016527237A JP2016535266A5 JP 2016535266 A5 JP2016535266 A5 JP 2016535266A5 JP 2016527237 A JP2016527237 A JP 2016527237A JP 2016527237 A JP2016527237 A JP 2016527237A JP 2016535266 A5 JP2016535266 A5 JP 2016535266A5
- Authority
- JP
- Japan
- Prior art keywords
- molecule
- analyte
- binding
- trapping
- binding molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012491 analyte Substances 0.000 claims 39
- 238000001514 detection method Methods 0.000 claims 19
- 238000000034 method Methods 0.000 claims 14
- 239000012634 fragment Substances 0.000 claims 5
- 210000004369 blood Anatomy 0.000 claims 4
- 239000008280 blood Substances 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 230000004797 therapeutic response Effects 0.000 claims 3
- 238000003556 assay Methods 0.000 claims 2
- 239000000090 biomarker Substances 0.000 claims 2
- 238000004140 cleaning Methods 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000007788 liquid Substances 0.000 claims 2
- 108010038988 Peptide Hormones Proteins 0.000 claims 1
- 102000015731 Peptide Hormones Human genes 0.000 claims 1
- 239000000427 antigen Substances 0.000 claims 1
- 102000036639 antigens Human genes 0.000 claims 1
- 108091007433 antigens Proteins 0.000 claims 1
- 238000012875 competitive assay Methods 0.000 claims 1
- 239000000032 diagnostic agent Substances 0.000 claims 1
- 229940039227 diagnostic agent Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000002372 labelling Methods 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 230000036963 noncompetitive effect Effects 0.000 claims 1
- 238000011275 oncology therapy Methods 0.000 claims 1
- 239000000813 peptide hormone Substances 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- 239000000439 tumor marker Substances 0.000 claims 1
- 238000005406 washing Methods 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13005218.6 | 2013-11-05 | ||
| EP13005218 | 2013-11-05 | ||
| EP14002015.7 | 2014-06-11 | ||
| EP14002015 | 2014-06-11 | ||
| PCT/EP2014/073523 WO2015067547A1 (en) | 2013-11-05 | 2014-11-03 | A method for determining the total amount and/or concentration of an analyte in the presence of a binding molecule as well as kits, compositions and uses relating thereto |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016535266A JP2016535266A (ja) | 2016-11-10 |
| JP2016535266A5 true JP2016535266A5 (enExample) | 2017-11-16 |
| JP6446044B2 JP6446044B2 (ja) | 2018-12-26 |
Family
ID=51845410
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016527237A Active JP6446044B2 (ja) | 2013-11-05 | 2014-11-03 | 結合分子の存在下で被検体の総量および／または総濃度を決定するための方法、ならびにそれに関係するキット、組成物および使用 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US10564151B2 (enExample) |
| EP (1) | EP3066469B1 (enExample) |
| JP (1) | JP6446044B2 (enExample) |
| CN (1) | CN105683755B (enExample) |
| CA (1) | CA2926306C (enExample) |
| ES (1) | ES2654906T3 (enExample) |
| WO (1) | WO2015067547A1 (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108700576B (zh) * | 2017-01-20 | 2021-07-02 | 深圳市新产业生物医学工程股份有限公司 | 制备抗体对的方法、试剂盒及试剂盒的应用和制备抗体对的系统 |
| WO2024158727A2 (en) * | 2023-01-24 | 2024-08-02 | University Of Cincinnati | Depletion-limited analyte sensing with non-equilibrium binding probes |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4208479A (en) * | 1977-07-14 | 1980-06-17 | Syva Company | Label modified immunoassays |
| DE4214922C2 (de) | 1992-05-06 | 1996-06-13 | Brahms Diagnostica Gmbh | Verfahren zur quantitativen Bestimmung des Anteils der freien Form eines Schilddrüsenhormon-Liganden in einer biologischen Flüssigkeit und Kit zur Durchführung eines solchen Verfahrens |
| US5312730A (en) * | 1992-05-27 | 1994-05-17 | Ciba Corning Diagnostics Corp. | Immune complex transfer with lypophilic bridge |
| AU4482896A (en) * | 1995-01-31 | 1996-08-21 | Novo Nordisk A/S | A method of diagnosing preclinical diabetes |
| US6838250B2 (en) | 2000-03-31 | 2005-01-04 | Ortho-Clinical Diagnostics, Inc. | Immunoassay for C-reactive protein |
| CN1867587A (zh) * | 2003-08-14 | 2006-11-22 | 惠氏公司 | 抗Lewis Y抗独特型抗体及其用途 |
| WO2005108989A2 (en) * | 2004-04-16 | 2005-11-17 | Genentech, Inc. | Assay for antibodies |
| EP1861708A2 (en) * | 2005-03-08 | 2007-12-05 | Tanox, Inc. | Methods for determining the bivalency of protein and antibody therapeutics |
| CN101379399A (zh) | 2005-12-22 | 2009-03-04 | 罗姆股份有限公司 | 免疫测定装置和方法 |
| EP1801594A1 (en) * | 2005-12-23 | 2007-06-27 | Koninklijke Philips Electronics N.V. | Sensing device and method for determination of the amount of target molecule in an analyte |
| US20080127359A1 (en) * | 2006-11-06 | 2008-05-29 | Hermann Beck | Method for producing anti-idiotypic antibodies |
| TWI434855B (zh) * | 2006-11-21 | 2014-04-21 | Hoffmann La Roche | 結合物及其在免疫分析中作為參考標準之用途 |
| EP2193145A4 (en) | 2007-08-28 | 2011-05-18 | Abbott Biotech Ltd | COMPOSITIONS AND METHODS COMPRISING BINDING PROTEINS FOR ADALIMUMAB |
| FR2980271B1 (fr) * | 2011-09-16 | 2013-10-11 | Cisbio Bioassays | Procede de determination de la glycosylation d'un anticorps |
| BR112014011535A2 (pt) * | 2011-12-19 | 2017-05-09 | Hoffmann La Roche | método para a determinação in vitro e imunológica de presença da presença e/ou da quantidade de um parceiro de ligação, método in vitro e utilização de um anticorpo |
| CN104105966B (zh) * | 2012-02-01 | 2016-10-26 | 弗·哈夫曼-拉罗切有限公司 | 用于检测多特异性结合物的结合搭档的方法 |
| WO2014009474A1 (en) * | 2012-07-13 | 2014-01-16 | F. Hoffmann-La Roche Ag | Method for the detection of a multispecific binder |
| PE20160190A1 (es) * | 2013-08-01 | 2016-04-28 | Five Prime Therapeutics Inc | Anticuerpos anti-fgfr2iiib afucosilados |
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2014
- 2014-11-03 CA CA2926306A patent/CA2926306C/en active Active
- 2014-11-03 JP JP2016527237A patent/JP6446044B2/ja active Active
- 2014-11-03 ES ES14792817.0T patent/ES2654906T3/es active Active
- 2014-11-03 EP EP14792817.0A patent/EP3066469B1/en active Active
- 2014-11-03 CN CN201480060361.3A patent/CN105683755B/zh active Active
- 2014-11-03 WO PCT/EP2014/073523 patent/WO2015067547A1/en not_active Ceased
-
2016
- 2016-05-04 US US15/146,226 patent/US10564151B2/en active Active
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2020
- 2020-01-06 US US16/734,884 patent/US12158466B2/en active Active