JP2016534022A5 - - Google Patents

Info

Publication number

JP2016534022A5

JP2016534022A5 JP2016503264A JP2016503264A JP2016534022A5 JP 2016534022 A5 JP2016534022 A5 JP 2016534022A5 JP 2016503264 A JP2016503264 A JP 2016503264A JP 2016503264 A JP2016503264 A JP 2016503264A JP 2016534022 A5 JP2016534022 A5 JP 2016534022A5

Authority

JP

Japan

Prior art keywords

seq

sequence

variable region

set forth

heavy chain

Prior art date

2014-07-30

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 102000036639 antigens Human genes 0.000 claims 14
• 108091007433 antigens Proteins 0.000 claims 14
• 239000012634 fragment Substances 0.000 claims 13
• 210000003719 b-lymphocyte Anatomy 0.000 claims 12
• 239000008194 pharmaceutical composition Substances 0.000 claims 10
• 101001074382 Homo sapiens 5'-3' exonuclease PLD4 Proteins 0.000 claims 5
• 201000010099 disease Diseases 0.000 claims 5
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 5
• 102000043866 human PLD4 Human genes 0.000 claims 5
• 230000000694 effects Effects 0.000 claims 4
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• 101710142129 5'-3' exonuclease PLD4 Proteins 0.000 claims 2
• 102100036183 5'-3' exonuclease PLD4 Human genes 0.000 claims 2
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• 108010047041 Complementarity Determining Regions Proteins 0.000 claims 2
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• 238000000338 in vitro Methods 0.000 claims 2
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• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
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• 206010021245 Idiopathic thrombocytopenic purpura Diseases 0.000 claims 1
• 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
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• 208000005980 beta thalassemia Diseases 0.000 claims 1
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