JP2016533752A - オリゴヌクレオチドプローブおよびその使用 - Google Patents
オリゴヌクレオチドプローブおよびその使用 Download PDFInfo
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- JP2016533752A JP2016533752A JP2016537869A JP2016537869A JP2016533752A JP 2016533752 A JP2016533752 A JP 2016533752A JP 2016537869 A JP2016537869 A JP 2016537869A JP 2016537869 A JP2016537869 A JP 2016537869A JP 2016533752 A JP2016533752 A JP 2016533752A
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1048—SELEX
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/5308—Immunoassay; Biospecific binding assay; Materials therefor for analytes not provided for elsewhere, e.g. nucleic acids, uric acid, worms, mites
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/16—Aptamers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2525/00—Reactions involving modified oligonucleotides, nucleic acids, or nucleotides
- C12Q2525/10—Modifications characterised by
- C12Q2525/205—Aptamer
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Computational Biology (AREA)
Applications Claiming Priority (21)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361871107P | 2013-08-28 | 2013-08-28 | |
| US61/871,107 | 2013-08-28 | ||
| US201361874621P | 2013-09-06 | 2013-09-06 | |
| US61/874,621 | 2013-09-06 | ||
| US201361900975P | 2013-11-06 | 2013-11-06 | |
| US61/900,975 | 2013-11-06 | ||
| US201361912471P | 2013-12-05 | 2013-12-05 | |
| US61/912,471 | 2013-12-05 | ||
| US201461924192P | 2014-01-06 | 2014-01-06 | |
| US61/924,192 | 2014-01-06 | ||
| US201461949216P | 2014-03-06 | 2014-03-06 | |
| US61/949,216 | 2014-03-06 | ||
| US201461974949P | 2014-04-03 | 2014-04-03 | |
| US61/974,949 | 2014-04-03 | ||
| US201461990085P | 2014-05-07 | 2014-05-07 | |
| US61/990,085 | 2014-05-07 | ||
| US201461994704P | 2014-05-16 | 2014-05-16 | |
| US61/994,704 | 2014-05-16 | ||
| US201462024436P | 2014-07-14 | 2014-07-14 | |
| US62/024,436 | 2014-07-14 | ||
| PCT/US2014/053306 WO2015031694A2 (en) | 2013-08-28 | 2014-08-28 | Oligonucleotide probes and uses thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016533752A true JP2016533752A (ja) | 2016-11-04 |
| JP2016533752A5 JP2016533752A5 (cg-RX-API-DMAC7.html) | 2017-10-05 |
Family
ID=52587490
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016537869A Pending JP2016533752A (ja) | 2013-08-28 | 2014-08-28 | オリゴヌクレオチドプローブおよびその使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20160319361A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP3039174B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2016533752A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20160080815A (cg-RX-API-DMAC7.html) |
| CN (1) | CN105980615A (cg-RX-API-DMAC7.html) |
| AU (2) | AU2014312211A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112016004153A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2922689A1 (cg-RX-API-DMAC7.html) |
| IL (2) | IL244236A0 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2015031694A2 (cg-RX-API-DMAC7.html) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108866215A (zh) * | 2017-12-01 | 2018-11-23 | 苏州百源基因技术有限公司 | 一种用于产气肠杆菌检测的实时荧光定量pcr试剂盒 |
| JP2021528994A (ja) * | 2018-06-27 | 2021-10-28 | シーエス ジェネティックス リミテッドCs Genetics Limited | 循環微粒子を分析するための方法 |
| JP2022067460A (ja) * | 2020-10-20 | 2022-05-06 | 大塚製薬株式会社 | 細胞外小胞の内包物の測定方法および測定キット |
| JP2023526280A (ja) * | 2020-05-15 | 2023-06-21 | コーデックス ディーエヌエー インコーポレイテッド | ポリヌクレオチド配列のオンデマンド合成 |
Families Citing this family (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9599611B2 (en) | 2005-04-25 | 2017-03-21 | Trustees Of Boston University | Structured substrates for optical surface profiling |
| US10942184B2 (en) | 2012-10-23 | 2021-03-09 | Caris Science, Inc. | Aptamers and uses thereof |
| KR20150090072A (ko) | 2012-10-23 | 2015-08-05 | 카리스 라이프 사이언스 스위스 홀딩스 게엠베하 | 압타머 및 이의 용도 |
| AU2013361323B2 (en) | 2012-12-19 | 2018-09-06 | Caris Science, Inc. | Compositions and methods for aptamer screening |
| WO2015092020A2 (en) * | 2013-12-20 | 2015-06-25 | Université de Lausanne | Diagnostic, prognostic and therapeutic uses of long noncoding rnas for heart disease and regenerative medicine |
| EP3194979B1 (en) * | 2014-09-17 | 2021-12-22 | Wallac OY | Method for determining the risk of preterm birth |
| US20180066262A1 (en) | 2015-03-09 | 2018-03-08 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| US10772859B2 (en) | 2015-05-21 | 2020-09-15 | Indiana University Research And Technology Corporation | Methods of targeting APE/Ref-1 to inhibit hypoxia signaling genes |
| AU2016287499B2 (en) | 2015-06-29 | 2022-08-04 | Caris Science, Inc. | Therapeutic oligonucleotides |
| US10941176B2 (en) | 2015-07-28 | 2021-03-09 | Caris Science, Inc. | Therapeutic oligonucleotides |
| EP3353528B1 (en) | 2015-09-22 | 2023-11-29 | Trustees of Boston University | Multiplexed phenotyping of nanovesicles |
| WO2017112921A1 (en) * | 2015-12-24 | 2017-06-29 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Systems and methods for characterizing sepsis |
| AU2017214541B2 (en) | 2016-02-05 | 2024-03-21 | NanoView Biosciences, Inc. | Detection of exosomes having surface markers |
| WO2017161357A1 (en) | 2016-03-18 | 2017-09-21 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| SG10201911917WA (en) | 2016-05-02 | 2020-01-30 | Encodia Inc | Macromolecule analysis employing nucleic acid encoding |
| WO2017205686A1 (en) | 2016-05-25 | 2017-11-30 | Caris Science, Inc. | Oligonucleotide probes and uses thereof |
| MA45496A (fr) | 2016-06-17 | 2019-04-24 | Hoffmann La Roche | Molécules d'acide nucléique pour la réduction de l'arnm de padd5 ou pad7 pour le traitement d'une infection par l'hépatite b |
| WO2018081193A1 (en) * | 2016-10-25 | 2018-05-03 | Purdue Research Foundation | Conjugates for sensing |
| US20200058369A1 (en) * | 2016-11-02 | 2020-02-20 | Biois Co., Ltd. | Quantitative Cluster Analysis Method Of Target Protein By Using Next-Generation Sequencing And Use Thereof |
| CN110913910A (zh) * | 2017-05-08 | 2020-03-24 | 奥曼尼提纳米有限公司 | 快速进化的生物实体的治疗 |
| CN110662844A (zh) | 2017-05-22 | 2020-01-07 | 内盖夫生物技术国家研究所有限公司 | 用于肺癌的诊断的生物标志物 |
| AU2018281196B2 (en) | 2017-06-07 | 2022-04-28 | Gen-Probe Incorporated | Detecting Babesia species nucleic acid in a sample |
| CN109251980A (zh) * | 2017-07-14 | 2019-01-22 | 中国人民解放军第八医院 | 膀胱癌组织t细胞图谱模型及其构建方法和构建系统 |
| JP2019020206A (ja) * | 2017-07-14 | 2019-02-07 | 株式会社島津製作所 | 質量分析を用いた認知機能障害疾患バイオマーカーの定量方法及び質量分析装置 |
| KR102243415B1 (ko) * | 2017-09-27 | 2021-04-22 | ㈜로제타엑소좀 | 크기 배제 크로마토그래피를 이용한 세포밖 소포체의 분석 방법 및 이의 용도 |
| RU2766360C2 (ru) | 2017-10-16 | 2022-03-15 | Ф. Хоффманн-Ля Рош Аг | МОЛЕКУЛЫ НУКЛЕИНОВЫХ КИСЛОТ ДЛЯ УМЕНЬШЕНИЯ УРОВНЯ мРНК PAPD5 ИЛИ PAPD7 ДЛЯ ЛЕЧЕНИЯ ИНФЕКЦИОННОГО ГЕПАТИТА В |
| CA3081441C (en) | 2017-10-31 | 2023-08-29 | Encodia, Inc. | Kits for analysis using nucleic acid encoding and/or label |
| WO2019155050A1 (en) * | 2018-02-12 | 2019-08-15 | F. Hoffmann-La Roche Ag | Method of predicting response to therapy by assessing tumor genetic heterogeneity |
| CA3103054A1 (en) | 2018-07-03 | 2020-01-09 | F. Hoffmann-La Roche Ag | Oligonucleotides for modulating tau expression |
| JP7434276B2 (ja) * | 2018-07-26 | 2024-02-20 | ブラッコ・イメージング・ソシエタ・ペル・アチオニ | Icam-1アプタマー、その診断および治療用途 |
| US12331320B2 (en) | 2018-10-10 | 2025-06-17 | The Research Foundation For The State University Of New York | Genome edited cancer cell vaccines |
| US11608356B1 (en) * | 2019-02-22 | 2023-03-21 | Base Pair Biotechnologies, Inc. | Functional ligands to colistin |
| EP3931351B1 (en) * | 2019-03-01 | 2024-09-11 | Mercy Bioanalytics, Inc. | Method for target entity detection using ligase |
| CN109880903B (zh) * | 2019-03-01 | 2021-12-14 | 南京医科大学 | 一种用于非小细胞肺癌辅助诊断的snp标志物及其应用 |
| CN110045099B (zh) * | 2019-04-01 | 2022-03-04 | 四川大学华西医院 | 一种慢性阻塞性肺疾病检测试剂盒 |
| BR112021020411A2 (pt) * | 2019-04-11 | 2022-03-15 | Univ Arkansas | Aptâmeros de dna específicos para cd40 como adjuvantes de vacina |
| WO2020219923A1 (en) * | 2019-04-26 | 2020-10-29 | The Johns Hopkins University | Methods and materials for treating cancer |
| CA3138367A1 (en) | 2019-04-30 | 2020-11-05 | Encodia, Inc. | Methods for preparing analytes and related kits |
| CN110412281B (zh) * | 2019-06-26 | 2022-09-09 | 四川大学华西医院 | Begain自身抗体检测试剂在制备肺癌筛查试剂盒中的用途 |
| WO2021076808A1 (en) * | 2019-10-15 | 2021-04-22 | Cornell University | Methods for detecting and inhibiting brain metastasis |
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| CN119959532B (zh) * | 2025-01-03 | 2025-11-11 | 中国科学院精密测量科学与技术创新研究院 | 细胞色素c在制备elisa试剂盒方面的新用途 |
Citations (3)
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| CN108866215A (zh) * | 2017-12-01 | 2018-11-23 | 苏州百源基因技术有限公司 | 一种用于产气肠杆菌检测的实时荧光定量pcr试剂盒 |
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| JP2024119824A (ja) * | 2018-06-27 | 2024-09-03 | シーエス ジェネティックス リミテッド | 循環微粒子を分析するための方法 |
| JP2023526280A (ja) * | 2020-05-15 | 2023-06-21 | コーデックス ディーエヌエー インコーポレイテッド | ポリヌクレオチド配列のオンデマンド合成 |
| JP2022067460A (ja) * | 2020-10-20 | 2022-05-06 | 大塚製薬株式会社 | 細胞外小胞の内包物の測定方法および測定キット |
| JP7623124B2 (ja) | 2020-10-20 | 2025-01-28 | 大塚製薬株式会社 | 細胞外小胞の内包物の測定方法および測定キット |
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| EP3039174A4 (en) | 2017-09-27 |
| WO2015031694A3 (en) | 2015-06-04 |
| EP3039174B1 (en) | 2019-10-16 |
| IL269693A (en) | 2019-11-28 |
| IL244236A0 (en) | 2016-04-21 |
| CN105980615A (zh) | 2016-09-28 |
| US20160319361A1 (en) | 2016-11-03 |
| EP3039174A2 (en) | 2016-07-06 |
| AU2019200115A1 (en) | 2019-01-31 |
| US20210062270A1 (en) | 2021-03-04 |
| AU2014312211A1 (en) | 2016-03-10 |
| BR112016004153A2 (pt) | 2019-09-17 |
| CA2922689A1 (en) | 2015-03-05 |
| KR20160080815A (ko) | 2016-07-08 |
| WO2015031694A2 (en) | 2015-03-05 |
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