JP2016517275A - 多重核酸検出のためのコード化ナノポアセンサー - Google Patents

多重核酸検出のためのコード化ナノポアセンサー Download PDF

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JP2016517275A
JP2016517275A JP2016502813A JP2016502813A JP2016517275A JP 2016517275 A JP2016517275 A JP 2016517275A JP 2016502813 A JP2016502813 A JP 2016502813A JP 2016502813 A JP2016502813 A JP 2016502813A JP 2016517275 A JP2016517275 A JP 2016517275A
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probe
nucleic acid
target nucleic
probe molecule
capture region
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JP2016517275A5 (enExample
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グー リン−チュン
グー リン−チュン
ジャン シンユー
ジャン シンユー
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ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ
ザ キュレイターズ オブ ザ ユニバーシティ オブ ミズーリ
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Publication of JP2016517275A publication Critical patent/JP2016517275A/ja
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means
    • C12Q1/6825—Nucleic acid detection involving sensors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
    • G01N33/48721—Investigating individual macromolecules, e.g. by translocation through nanopores

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  • Life Sciences & Earth Sciences (AREA)
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
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  • Wood Science & Technology (AREA)
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  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
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  • Biotechnology (AREA)
  • Microbiology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
JP2016502813A 2013-03-15 2014-03-14 多重核酸検出のためのコード化ナノポアセンサー Pending JP2016517275A (ja)

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US201361788589P 2013-03-15 2013-03-15
US61/788,589 2013-03-15
PCT/US2014/028528 WO2014144217A1 (en) 2013-03-15 2014-03-14 Encoded nanopore sensor for multiplex nucleic acids detection

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JP2016517275A true JP2016517275A (ja) 2016-06-16
JP2016517275A5 JP2016517275A5 (enExample) 2017-04-20

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US (2) US9732379B2 (enExample)
EP (1) EP2971118B1 (enExample)
JP (1) JP2016517275A (enExample)
AU (1) AU2014227754B2 (enExample)
CA (1) CA2906007C (enExample)
WO (1) WO2014144217A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023062193A (ja) * 2018-06-26 2023-05-02 国立大学法人東京農工大学 検査対象が小細胞肺がん又は胆管がんに罹患している又はそのリスクを有することを判定する方法、並びに、これらの判定方法に用いるためのプローブ及びプローブセット

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CN105102627B (zh) * 2013-03-15 2018-10-19 纽约哥伦比亚大学理事会 用于检测样品中多种预定化合物的方法
US11098348B2 (en) 2015-02-02 2021-08-24 Ontera Inc. Nanopore detection of target polynucleotides from sample background
EP3303620A1 (en) 2015-06-02 2018-04-11 Nanopore Diagnostics LLC Nucleic acid detection
WO2018093976A1 (en) * 2016-11-16 2018-05-24 Nanopore Diagnostics, Llc Analysis of nucleic acids using probe with non-linear tag
US11034996B2 (en) 2018-03-02 2021-06-15 The Curators Of The University Of Missouri Nucleic acid sequence and capture by formation of an abasic site-derived cross-link
JP7377222B2 (ja) * 2018-06-21 2023-11-09 エフ． ホフマン－ラ ロシュ アーゲー 配列決定のためのトンネル接合部
JP7344786B2 (ja) * 2019-12-19 2023-09-14 株式会社日立製作所 溶液中の任意のｄｎａ配列を同定する方法
CN112795628B (zh) * 2021-02-05 2024-02-23 南京邮电大学 基于固态纳米孔传感器的miRNA检测方法、检测探针及试剂盒

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2023062193A (ja) * 2018-06-26 2023-05-02 国立大学法人東京農工大学 検査対象が小細胞肺がん又は胆管がんに罹患している又はそのリスクを有することを判定する方法、並びに、これらの判定方法に用いるためのプローブ及びプローブセット
JP7437824B2 (ja) 2018-06-26 2024-02-26 国立大学法人東京農工大学 検査対象が小細胞肺がん又は胆管がんに罹患している又はそのリスクを有することを判定する方法、並びに、これらの判定方法に用いるためのプローブ及びプローブセット

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EP2971118B1 (en) 2019-10-02
US20140309129A1 (en) 2014-10-16
CA2906007C (en) 2022-06-21
WO2014144217A1 (en) 2014-09-18
AU2014227754B2 (en) 2018-03-01
EP2971118A1 (en) 2016-01-20
AU2014227754A1 (en) 2015-10-01
EP2971118A4 (en) 2016-11-16
US9732379B2 (en) 2017-08-15
CA2906007A1 (en) 2014-09-18
US20180002742A1 (en) 2018-01-04

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