JP2016515620A5 - - Google Patents
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- Publication number
- JP2016515620A5 JP2016515620A5 JP2016506353A JP2016506353A JP2016515620A5 JP 2016515620 A5 JP2016515620 A5 JP 2016515620A5 JP 2016506353 A JP2016506353 A JP 2016506353A JP 2016506353 A JP2016506353 A JP 2016506353A JP 2016515620 A5 JP2016515620 A5 JP 2016515620A5
- Authority
- JP
- Japan
- Prior art keywords
- xaa
- group
- lys
- ala
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361807713P | 2013-04-02 | 2013-04-02 | |
| US61/807,713 | 2013-04-02 | ||
| US14/229,799 US20140294902A1 (en) | 2013-04-02 | 2014-03-28 | Novel a4b7 peptide antagonists |
| US14/229,799 | 2014-03-28 | ||
| PCT/US2014/032392 WO2014165449A1 (en) | 2013-04-02 | 2014-03-31 | NOVEL α4β7 PEPTIDE ANTAGONISTS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016515620A JP2016515620A (ja) | 2016-05-30 |
| JP2016515620A5 true JP2016515620A5 (enExample) | 2017-05-18 |
Family
ID=51621090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016506353A Pending JP2016515620A (ja) | 2013-04-02 | 2014-03-31 | 新規のα４β７ペプチド拮抗薬 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20140294902A1 (enExample) |
| EP (1) | EP2981543A4 (enExample) |
| JP (1) | JP2016515620A (enExample) |
| WO (1) | WO2014165449A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9273093B2 (en) | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
| PT2968443T (pt) | 2013-03-15 | 2021-12-28 | Protagonist Therapeutics Inc | Análogos de hepcidina e seus usos |
| SG10201810321PA (en) | 2014-05-16 | 2018-12-28 | Protagonist Therapeutics Inc | α4β7 INTEGRIN THIOETHER PEPTIDE ANTAGONISTS |
| ES2977537T3 (es) | 2014-07-17 | 2024-08-26 | Protagonist Therapeutics Inc | Inhibidores peptídicos orales del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias intestinales |
| US10301371B2 (en) | 2014-10-01 | 2019-05-28 | Protagonist Therapeutics, Inc. | Cyclic monomer and dimer peptides having integrin antagonist activity |
| SG11201702553RA (en) | 2014-10-01 | 2017-04-27 | Protagonist Therapeutics Inc | NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| WO2017117411A1 (en) | 2015-12-30 | 2017-07-06 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| US10407468B2 (en) | 2016-03-23 | 2019-09-10 | Protagonist Therapeutics, Inc. | Methods for synthesizing α4β7 peptide antagonists |
| CN106366160B (zh) * | 2016-10-11 | 2019-06-14 | 厦门大学 | 基于二硫键精准配对构建富含二硫键多肽分子骨架的方法 |
| EP4092038A1 (en) | 2017-09-11 | 2022-11-23 | Protagonist Therapeutics, Inc. | Opioid agonist peptides and uses thereof |
| EP4501952A3 (en) | 2018-02-08 | 2025-04-16 | Protagonist Therapeutics, Inc. | Conjugated hepcidin mimetics |
| WO2019239126A1 (en) * | 2018-06-13 | 2019-12-19 | Immune Regulation Limited | Novel protein with anti-inflammatory properties |
| EP3997105A4 (en) | 2019-07-10 | 2023-09-13 | Protagonist Therapeutics, Inc. | PEPTIDE INHIBITORS OF THE INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES |
| CN115279782A (zh) | 2020-01-15 | 2022-11-01 | 詹森生物科技公司 | 白介素-23受体的肽抑制剂及其用于治疗炎性疾病的用途 |
| IL294680A (en) | 2020-01-15 | 2022-09-01 | Janssen Biotech Inc | Peptide inhibitors of the interleukin-23 receptor and their use for the treatment of inflammatory diseases |
| IL302996B2 (en) | 2020-11-20 | 2025-04-01 | Janssen Pharmaceutica Nv | Compositions of interleukin-23 receptor peptide inhibitors |
| AU2022311814A1 (en) | 2021-07-14 | 2024-02-29 | Janssen Biotech, Inc. | Lipidated peptide inhibitors of interleukin-23 receptor |
| US20230145835A1 (en) * | 2021-10-06 | 2023-05-11 | 48Hd Biopharma Inc. | Modulators of Alpha-4-beta-7 Integrin and MAdCAM |
| CN116098884B (zh) * | 2022-12-12 | 2024-04-19 | 山东大学 | 一种n-乙酰-l-酪氨酸在制备治疗炎症性肠病药物中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69226077T2 (de) * | 1991-04-05 | 1998-12-03 | Genentech, Inc., South San Francisco, Calif. | PLAETTCHENAGGREGATIONSINHIBITOREN MIT HOHER SPEZIFIZITAET ZUM GP IIbIIIa |
| GB9613112D0 (en) * | 1996-06-21 | 1996-08-28 | Zeneca Ltd | Chemical compounds |
| EP0998309A1 (en) * | 1997-07-11 | 2000-05-10 | Innerdyne Medical, Inc. | Methods and systems for preparing and sealing radiation delivery structures |
| JP2002524108A (ja) * | 1998-07-28 | 2002-08-06 | インナーダイン， インコーポレイテッド | 吸収性近接照射療法および化学療法送達デバイスならびに方法 |
| WO2001068586A2 (en) * | 2000-03-14 | 2001-09-20 | Novartis Ag | α4β1 AND α4β7 INTEGRIN INHIBITORS |
| RU2292904C2 (ru) * | 2001-01-09 | 2007-02-10 | Мерк Патент Гмбх | Комбинированная терапия, использующая ингибиторы рецептора тирозинкиназы и ингибиторы ангиогенезиса |
| DE10107707A1 (de) * | 2001-02-19 | 2002-08-29 | Wilex Biotechnology Gmbh | Antagonisten für alpha¶4¶beta¶7¶-Integrin |
| GB0610395D0 (en) * | 2006-05-25 | 2006-07-05 | Ge Healthcare Ltd | Novel imaging agents |
| WO2008140602A2 (en) * | 2006-12-07 | 2008-11-20 | The Govenment Of The Usa As Represented By The Secretary Of The Dept. Of Health And Human Services | USE OF ANTAGONISTS OF THE INTERACTION BETWEEN HIV GP120 AND α4β7 INTEGRIN |
| CN104725472A (zh) * | 2010-01-25 | 2015-06-24 | 康奈尔大学 | 芳香族阳离子肽及其用途 |
| JP2011231085A (ja) * | 2010-04-30 | 2011-11-17 | Osaka Prefecture Univ | 環状ペプチド |
| EP2444101A1 (en) * | 2010-10-21 | 2012-04-25 | Universitätsklinikum Freiburg | Selective targeting of the CD40L/Mac-1 interaction by small peptide inhibitors and its use for the treatment of inflammation and atherogenesis |
-
2014
- 2014-03-28 US US14/229,799 patent/US20140294902A1/en not_active Abandoned
- 2014-03-31 JP JP2016506353A patent/JP2016515620A/ja active Pending
- 2014-03-31 EP EP14780207.8A patent/EP2981543A4/en not_active Withdrawn
- 2014-03-31 WO PCT/US2014/032392 patent/WO2014165449A1/en not_active Ceased
-
2019
- 2019-02-22 US US16/282,920 patent/US20200017549A1/en not_active Abandoned
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