JP2016515620A5 - - Google Patents
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- Publication number
- JP2016515620A5 JP2016515620A5 JP2016506353A JP2016506353A JP2016515620A5 JP 2016515620 A5 JP2016515620 A5 JP 2016515620A5 JP 2016506353 A JP2016506353 A JP 2016506353A JP 2016506353 A JP2016506353 A JP 2016506353A JP 2016515620 A5 JP2016515620 A5 JP 2016515620A5
- Authority
- JP
- Japan
- Prior art keywords
- xaa
- group
- lys
- ala
- phe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361807713P | 2013-04-02 | 2013-04-02 | |
| US61/807,713 | 2013-04-02 | ||
| US14/229,799 US20140294902A1 (en) | 2013-04-02 | 2014-03-28 | Novel a4b7 peptide antagonists |
| US14/229,799 | 2014-03-28 | ||
| PCT/US2014/032392 WO2014165449A1 (en) | 2013-04-02 | 2014-03-31 | NOVEL α4β7 PEPTIDE ANTAGONISTS |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016515620A JP2016515620A (ja) | 2016-05-30 |
| JP2016515620A5 true JP2016515620A5 (enExample) | 2017-05-18 |
Family
ID=51621090
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016506353A Pending JP2016515620A (ja) | 2013-04-02 | 2014-03-31 | 新規のα４β７ペプチド拮抗薬 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US20140294902A1 (enExample) |
| EP (1) | EP2981543A4 (enExample) |
| JP (1) | JP2016515620A (enExample) |
| WO (1) | WO2014165449A1 (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9273093B2 (en) | 2012-10-11 | 2016-03-01 | Protagonist Therapeutics, Inc. | α4β7 peptide dimer antagonists |
| KR102236829B1 (ko) | 2013-03-15 | 2021-04-07 | 프로타고니스트 테라퓨틱스, 인코포레이티드 | 헵시딘 유사체 및 이의 용도 |
| AU2015258863B2 (en) | 2014-05-16 | 2019-10-24 | Protagonist Therapeutics, Inc. | Alpha4beta7 integrin thioether peptide antagonists |
| AU2015289642B2 (en) | 2014-07-17 | 2021-02-25 | Protagonist Therapeutics, Inc. | Oral peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory bowel diseases |
| WO2016054411A1 (en) | 2014-10-01 | 2016-04-07 | Protagonist Therapeutics, Inc. | NOVEL α4β7 PEPTIDE MONOMER AND DIMER ANTAGONISTS |
| EP3201217A4 (en) | 2014-10-01 | 2018-07-18 | Protagonist Therapeutics Inc. | Novel cyclic monomer and dimer peptides having integrin antagonist activity |
| US10787490B2 (en) | 2015-07-15 | 2020-09-29 | Protaganist Therapeutics, Inc. | Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases |
| WO2017117411A1 (en) | 2015-12-30 | 2017-07-06 | Protagonist Therapeutics, Inc. | Analogues of hepcidin mimetics with improved in vivo half lives |
| EP3432906A4 (en) | 2016-03-23 | 2020-04-01 | Protagonist Therapeutics, Inc. | METHOD FOR SYNTHETIZING ALPHA4BETA7 PEPTIDE ANTAGONISTS |
| CN106366160B (zh) * | 2016-10-11 | 2019-06-14 | 厦门大学 | 基于二硫键精准配对构建富含二硫键多肽分子骨架的方法 |
| US10278957B2 (en) | 2017-09-11 | 2019-05-07 | Protagonist Therapeutics, Inc. | Opioid agonist peptides and uses thereof |
| EP3749345A4 (en) | 2018-02-08 | 2022-04-06 | Protagonist Therapeutics, Inc. | CONJUGATED HEPCIDIN MIMETICS |
| BR112020025398A2 (pt) * | 2018-06-13 | 2021-04-06 | Immune Regulation Limited | Proteína com propriedades anti-inflamatórias |
| TW202019948A (zh) | 2018-07-12 | 2020-06-01 | 美商領導醫療有限公司 | 介白素-23受體之肽抑制劑及其治療發炎疾病之用途 |
| MX2022000397A (es) | 2019-07-10 | 2022-04-25 | Protagonist Therapeutics Inc | Inhibidores peptídicos del receptor de interleucina-23 y su uso para tratar enfermedades inflamatorias. |
| CN118063554A (zh) | 2020-01-15 | 2024-05-24 | 詹森生物科技公司 | 介白素-23受体的肽抑制剂及其治疗炎性疾病的用途 |
| KR20220141808A (ko) | 2020-01-15 | 2022-10-20 | 얀센 바이오테크 인코포레이티드 | 인터루킨-23 수용체의 펩티드 억제제 및 염증성 질환을 치료하기 위한 이의 용도 |
| KR20230110570A (ko) | 2020-11-20 | 2023-07-24 | 얀센 파마슈티카 엔.브이. | 인터류킨-23 수용체의 펩티드 억제제의 조성물 |
| TW202330013A (zh) | 2021-07-14 | 2023-08-01 | 美商健生生物科技公司 | 介白素－２３受體之脂化肽抑制劑 |
| US20230145835A1 (en) * | 2021-10-06 | 2023-05-11 | 48Hd Biopharma Inc. | Modulators of Alpha-4-beta-7 Integrin and MAdCAM |
| CN116098884B (zh) * | 2022-12-12 | 2024-04-19 | 山东大学 | 一种n-乙酰-l-酪氨酸在制备治疗炎症性肠病药物中的应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2106314A1 (en) * | 1991-04-05 | 1992-10-06 | John P. Burnier | Platelet aggregation inhibitors having high specification for gpiibiiia |
| GB9613112D0 (en) * | 1996-06-21 | 1996-08-28 | Zeneca Ltd | Chemical compounds |
| JP2001509493A (ja) * | 1997-07-11 | 2001-07-24 | インナーダイン， インコーポレイテッド | 放射送達構造体の調製およびシール化のための方法およびシステム |
| EP1100473A2 (en) * | 1998-07-28 | 2001-05-23 | InnerDyne, Inc. | Absorbable brachytherapy and chemotherapy delivery devices and methods |
| AU2001262089A1 (en) * | 2000-03-14 | 2001-09-24 | Novartis Ag | Alpha4beta1 and alpha4beta7 integrin inhibitors |
| KR20030068205A (ko) * | 2001-01-09 | 2003-08-19 | 메르크 파텐트 게엠베하 | 수용체 타이로신 키나아제 저해제 및 혈관형성 저해제를사용하는 병용 요법 |
| DE10107707A1 (de) * | 2001-02-19 | 2002-08-29 | Wilex Biotechnology Gmbh | Antagonisten für alpha¶4¶beta¶7¶-Integrin |
| GB0610395D0 (en) * | 2006-05-25 | 2006-07-05 | Ge Healthcare Ltd | Novel imaging agents |
| US9193790B2 (en) * | 2006-12-07 | 2015-11-24 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Use of antagonists of the interaction between HIV GP120 and A4B7 integrin |
| WO2011091357A1 (en) * | 2010-01-25 | 2011-07-28 | Cornell University | Aromatic-cationic peptides and uses of same |
| JP2011231085A (ja) * | 2010-04-30 | 2011-11-17 | Osaka Prefecture Univ | 環状ペプチド |
| EP2444101A1 (en) * | 2010-10-21 | 2012-04-25 | Universitätsklinikum Freiburg | Selective targeting of the CD40L/Mac-1 interaction by small peptide inhibitors and its use for the treatment of inflammation and atherogenesis |
-
2014
- 2014-03-28 US US14/229,799 patent/US20140294902A1/en not_active Abandoned
- 2014-03-31 WO PCT/US2014/032392 patent/WO2014165449A1/en not_active Ceased
- 2014-03-31 JP JP2016506353A patent/JP2016515620A/ja active Pending
- 2014-03-31 EP EP14780207.8A patent/EP2981543A4/en not_active Withdrawn
-
2019
- 2019-02-22 US US16/282,920 patent/US20200017549A1/en not_active Abandoned
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