JP2016514957A5 - - Google Patents

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Publication number
JP2016514957A5
JP2016514957A5 JP2015561647A JP2015561647A JP2016514957A5 JP 2016514957 A5 JP2016514957 A5 JP 2016514957A5 JP 2015561647 A JP2015561647 A JP 2015561647A JP 2015561647 A JP2015561647 A JP 2015561647A JP 2016514957 A5 JP2016514957 A5 JP 2016514957A5
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JP
Japan
Prior art keywords
host cell
cell according
recombinant polypeptide
acid sequence
nucleic acid
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JP2015561647A
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English (en)
Japanese (ja)
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JP2016514957A (ja
JP6742729B2 (ja
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Priority claimed from PCT/US2014/021137 external-priority patent/WO2014138371A1/en
Publication of JP2016514957A publication Critical patent/JP2016514957A/ja
Publication of JP2016514957A5 publication Critical patent/JP2016514957A5/ja
Application granted granted Critical
Publication of JP6742729B2 publication Critical patent/JP6742729B2/ja
Expired - Fee Related legal-status Critical Current
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JP2015561647A 2013-03-06 2014-03-06 宿主細胞および使用方法 Expired - Fee Related JP6742729B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361773329P 2013-03-06 2013-03-06
US61/773,329 2013-03-06
PCT/US2014/021137 WO2014138371A1 (en) 2013-03-06 2014-03-06 Host cells and methods of use

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019044077A Division JP2019122395A (ja) 2013-03-06 2019-03-11 宿主細胞および使用方法

Publications (3)

Publication Number Publication Date
JP2016514957A JP2016514957A (ja) 2016-05-26
JP2016514957A5 true JP2016514957A5 (https=) 2017-04-13
JP6742729B2 JP6742729B2 (ja) 2020-08-19

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ID=51491943

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JP2015561647A Expired - Fee Related JP6742729B2 (ja) 2013-03-06 2014-03-06 宿主細胞および使用方法
JP2019044077A Pending JP2019122395A (ja) 2013-03-06 2019-03-11 宿主細胞および使用方法

Family Applications After (1)

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JP2019044077A Pending JP2019122395A (ja) 2013-03-06 2019-03-11 宿主細胞および使用方法

Country Status (11)

Country Link
US (1) US9926570B2 (https=)
EP (1) EP2964666B1 (https=)
JP (2) JP6742729B2 (https=)
KR (1) KR20150126839A (https=)
AU (1) AU2014225678B2 (https=)
BR (1) BR112015021960A2 (https=)
CA (1) CA2903739A1 (https=)
ES (1) ES2843679T3 (https=)
RU (1) RU2663587C2 (https=)
SG (1) SG11201504771RA (https=)
WO (1) WO2014138371A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015001049A1 (en) 2013-07-04 2015-01-08 Novartis Ag O-mannosyltransferase deficient filamentous fungal cells and methods of use thereof
SG11201700446XA (en) 2014-07-21 2017-02-27 Glykos Finland Oy Production of glycoproteins with mammalian-like n-glycans in filamentous fungi
EP3394243A1 (en) 2015-12-22 2018-10-31 Albumedix Ltd. Improved protein expression strains
JP7146637B2 (ja) 2015-12-22 2022-10-04 アルブミディクス リミティド 改善されたタンパク質発現株
CN105950491B (zh) * 2016-05-23 2019-08-06 江南大学 一种高效表达碱性果胶酶的菌株及其构建与应用
US11130979B2 (en) 2017-06-20 2021-09-28 Albumedix Ltd Protein expression strains
KR101984957B1 (ko) 2017-08-09 2019-06-04 재단법인 지능형 바이오 시스템 설계 및 합성 연구단 효모의 단백질 접힘 기작(protein-folding machinery) 개량을 통한 진세노사이드 생산 증대
US11135276B2 (en) 2019-05-17 2021-10-05 Imam Abdulrahman Bin Faisal University Method of making PDIA2 and compositions containing PDIA2
EP3992221A4 (en) 2019-06-28 2023-06-21 Mitsubishi Gas Chemical Company, Inc. RESIN COMPOSITION, RESIN FILM, LAYER PRODUCT, SEMICONDUCTOR WAFER WITH RESIN COMPOSITION LAYER, SUBSTRATE WITH RESIN COMPOSITION LAYER FOR SEMICONDUCTOR MOUNTING, AND SEMICONDUCTOR DEVICE
EP4402257A4 (en) * 2021-09-17 2025-08-27 Univ North Carolina Chapel Hill MODIFIED PROTEIN DISULFIDE ISOMERASE AND ITS USES
GB202301988D0 (en) * 2023-02-13 2023-03-29 Phenotypeca Ltd Breeding process

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5077204A (en) 1984-06-21 1991-12-31 Chiron Corporation Yeast endopeptidase for basic amino-acid site cleavage, preparation and use
JP2643968B2 (ja) 1988-02-03 1997-08-25 サントリー株式会社 Kex2エンドプロテアーゼ及びその製造方法
FR2645174B1 (fr) 1989-03-31 1994-01-07 Transgene Sa Souches de levure ameliorees pour la production de proteines heterologues matures en particulier d'hirudine et procede de preparation d'hirudine correspondant
US5545618A (en) 1990-01-24 1996-08-13 Buckley; Douglas I. GLP-1 analogs useful for diabetes treatment
GB9015825D0 (en) 1990-07-18 1990-09-05 Ciba Geigy Ag In vitro processing of fusion proteins
ATE157703T1 (de) 1991-12-16 1997-09-15 Ciba Geigy Ag Endoplasmatisches retikulum-ständige rekombinante dibasische endoprotease und deren verwendungen
US6291205B1 (en) 1992-06-12 2001-09-18 Merck & Co., Inc. Method of increasing production of disulfide bonded recombinant proteins by saccharomyces cerevisiae
GB9404270D0 (en) 1994-03-05 1994-04-20 Delta Biotechnology Ltd Yeast strains and modified albumins
GB9411356D0 (en) 1994-06-07 1994-07-27 Delta Biotechnology Ltd Yeast strains
CA2198968C (en) 1996-03-04 2010-02-09 Toyofumi Masuda Process for production of secretory kex2 derivatives
CA2258307C (en) * 1996-07-05 2008-02-12 Novo Nordisk A/S Method of producing heterologous short chain polypeptides by yeast with impaired yap3 protease
US7504493B2 (en) 1997-01-23 2009-03-17 The John Hopkins University Characterization of the yeast transcriptome
GB9713412D0 (en) 1997-06-26 1997-08-27 Delta Biotechnology Ltd Improved protein expression strains
US6361964B1 (en) * 1997-08-12 2002-03-26 Massachusetts Institute Of Technology Eukaryotic disulfide bond-forming proteins and related molecules and methods
IL127127A0 (en) 1998-11-18 1999-09-22 Peptor Ltd Small functional units of antibody heavy chain variable regions
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
AU2002364586A1 (en) * 2001-12-21 2003-07-30 Delta Biotechnology Limited Albumin fusion proteins
HUE027902T2 (en) 2004-02-09 2016-11-28 Human Genome Sciences Inc Corp Service Company Albumin fusion proteins
US20060046253A1 (en) * 2004-09-02 2006-03-02 Suntory Limited Method for analyzing genes of industrial yeasts
DE502005005689D1 (de) 2005-05-04 2008-11-27 Signalomics Gmbh Kompetitives n-Hybrid System
US8202837B2 (en) * 2005-11-04 2012-06-19 Glaxosmithkline Llc Methods for administering hypoglycemic agents
JP5354559B2 (ja) 2005-11-24 2013-11-27 独立行政法人産業技術総合研究所 高効率分泌シグナルペプチド及びそれらを利用したタンパク質発現系
SG175602A1 (en) 2006-07-05 2011-11-28 Catalyst Biosciences Inc Protease screening methods and proteases identified thereby
US8034607B2 (en) 2007-09-12 2011-10-11 Wisconsin Alumni Research Foundation Methods of enhanced heterologous protein secretion
ES2537806T5 (es) * 2007-10-31 2018-10-09 Daiichi Sankyo Company, Limited Método para la secreción y producción de alto nivel de proteína
WO2009082209A1 (en) 2007-12-21 2009-07-02 Fujifilm Manufacturing Europe B.V. Improvement of the secretion yield of a protein of interest by in vivo proteolytic processing of a multimeric precursor
US20110129872A1 (en) * 2009-12-01 2011-06-02 Mogam Biotechnology Research Institute Method for a production of a recombinant protein using yeast co-expression system
RU2427645C1 (ru) * 2010-06-10 2011-08-27 Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") СПОСОБ МИКРОБИОЛОГИЧЕСКОГО СИНТЕЗА ЗРЕЛОГО ИНТЕРФЕРОНА АЛЬФА-2 ЧЕЛОВЕКА, ШТАММ Saccharomyces cerevisiae - ПРОДУЦЕНТ ЗРЕЛОГО ИНТЕРФЕРОНА АЛЬФА-2 ЧЕЛОВЕКА (ВАРИАНТЫ)
MX2015005363A (es) * 2012-11-08 2015-11-06 Novozymes Biopharma Dk As Variantes de albumina.

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