JP2016512839A5 - - Google Patents

Info

Publication number

JP2016512839A5

JP2016512839A5 JP2016501894A JP2016501894A JP2016512839A5 JP 2016512839 A5 JP2016512839 A5 JP 2016512839A5 JP 2016501894 A JP2016501894 A JP 2016501894A JP 2016501894 A JP2016501894 A JP 2016501894A JP 2016512839 A5 JP2016512839 A5 JP 2016512839A5

Authority

JP

Japan

Prior art keywords

carrier material

composition

composition according

weight

therapeutic agent

Prior art date

2014-03-13

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 239000012876 carrier material Substances 0.000 claims 21
• 239000003814 drug Substances 0.000 claims 8
• 239000011148 porous material Substances 0.000 claims 8
• 229940124597 therapeutic agent Drugs 0.000 claims 7
• 238000000034 method Methods 0.000 claims 6
• 239000000126 substance Substances 0.000 claims 6
• 230000001225 therapeutic effect Effects 0.000 claims 6
• 229920000642 polymer Polymers 0.000 claims 4
• 229910021426 porous silicon Inorganic materials 0.000 claims 3
• 238000013270 controlled release Methods 0.000 claims 2
• 239000000463 material Substances 0.000 claims 2
• HDTRYLNUVZCQOY-UHFFFAOYSA-N α-D-glucopyranosyl-α-D-glucopyranoside Natural products OC1C(O)C(O)C(CO)OC1OC1C(O)C(O)C(O)C(CO)O1 HDTRYLNUVZCQOY-UHFFFAOYSA-N 0.000 claims 1
• DPVHGFAJLZWDOC-PVXXTIHASA-N (2r,3s,4s,5r,6r)-2-(hydroxymethyl)-6-[(2r,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoxane-3,4,5-triol;dihydrate Chemical compound O.O.O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DPVHGFAJLZWDOC-PVXXTIHASA-N 0.000 claims 1
• FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
• FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
• FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
• 229930195725 Mannitol Natural products 0.000 claims 1
• CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims 1
• 229930006000 Sucrose Natural products 0.000 claims 1
• HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims 1
• TVXBFESIOXBWNM-UHFFFAOYSA-N Xylitol Natural products OCCC(O)C(O)C(O)CCO TVXBFESIOXBWNM-UHFFFAOYSA-N 0.000 claims 1
• HDTRYLNUVZCQOY-LIZSDCNHSA-N alpha,alpha-trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims 1
• 235000014633 carbohydrates Nutrition 0.000 claims 1
• 150000001720 carbohydrates Chemical class 0.000 claims 1
• 239000000594 mannitol Substances 0.000 claims 1
• 235000010355 mannitol Nutrition 0.000 claims 1
• 229960001855 mannitol Drugs 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• HEBKCHPVOIAQTA-UHFFFAOYSA-N meso ribitol Natural products OCC(O)C(O)C(O)CO HEBKCHPVOIAQTA-UHFFFAOYSA-N 0.000 claims 1
• 102000040430 polynucleotide Human genes 0.000 claims 1
• 108091033319 polynucleotide Proteins 0.000 claims 1
• 239000002157 polynucleotide Substances 0.000 claims 1
• 102000004196 processed proteins & peptides Human genes 0.000 claims 1
• 108090000765 processed proteins & peptides Proteins 0.000 claims 1
• 102000004169 proteins and genes Human genes 0.000 claims 1
• 108090000623 proteins and genes Proteins 0.000 claims 1
• 239000000600 sorbitol Substances 0.000 claims 1
• 229960002920 sorbitol Drugs 0.000 claims 1
• 235000010356 sorbitol Nutrition 0.000 claims 1
• 239000005720 sucrose Substances 0.000 claims 1
• 229960004793 sucrose Drugs 0.000 claims 1
• 229940074410 trehalose Drugs 0.000 claims 1
• 229940074409 trehalose dihydrate Drugs 0.000 claims 1
• 239000000811 xylitol Substances 0.000 claims 1
• 235000010447 xylitol Nutrition 0.000 claims 1
• HEBKCHPVOIAQTA-SCDXWVJYSA-N xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 1
• 229960002675 xylitol Drugs 0.000 claims 1