JP2016510795A - 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用 - Google Patents

心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用 Download PDF

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JP2016510795A
JP2016510795A JP2015562201A JP2015562201A JP2016510795A JP 2016510795 A JP2016510795 A JP 2016510795A JP 2015562201 A JP2015562201 A JP 2015562201A JP 2015562201 A JP2015562201 A JP 2015562201A JP 2016510795 A JP2016510795 A JP 2016510795A
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linagliptin
disease
patients
diabetic
patient
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JP2016510795A5 (enExample
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オッド−エリック ヨハンセン
オッド−エリック ヨハンセン
エイナッテン マクシミリアン フォン
エイナッテン マクシミリアン フォン
トマス クライン
トマス クライン
ハンス−ユルゲン ヴォーレ
ハンス−ユルゲン ヴォーレ
Original Assignee
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
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Application filed by ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング, ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング filed Critical ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング
Publication of JP2016510795A publication Critical patent/JP2016510795A/ja
Publication of JP2016510795A5 publication Critical patent/JP2016510795A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2015562201A 2013-03-15 2014-03-14 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用 Pending JP2016510795A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP13159624 2013-03-15
EP13159624.9 2013-03-15
EP13177311.1 2013-07-19
EP13177311 2013-07-19
PCT/EP2014/055113 WO2014140284A1 (en) 2013-03-15 2014-03-14 Use of linagliptin in cardio- and renoprotective antidiabetic therapy

Related Child Applications (1)

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JP2019022289A Division JP2019112409A (ja) 2013-03-15 2019-02-12 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用

Publications (2)

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JP2016510795A true JP2016510795A (ja) 2016-04-11
JP2016510795A5 JP2016510795A5 (enExample) 2017-04-20

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JP2015562201A Pending JP2016510795A (ja) 2013-03-15 2014-03-14 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用
JP2019022289A Pending JP2019112409A (ja) 2013-03-15 2019-02-12 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用
JP2021030485A Pending JP2021095409A (ja) 2013-03-15 2021-02-26 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用
JP2025074372A Pending JP2025115998A (ja) 2013-03-15 2025-04-28 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用

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JP2019022289A Pending JP2019112409A (ja) 2013-03-15 2019-02-12 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用
JP2021030485A Pending JP2021095409A (ja) 2013-03-15 2021-02-26 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用
JP2025074372A Pending JP2025115998A (ja) 2013-03-15 2025-04-28 心臓保護及び腎臓保護の抗糖尿病治療におけるリナグリプチンの使用

Country Status (14)

Country Link
US (9) US20140274889A1 (enExample)
EP (4) EP3744327A1 (enExample)
JP (4) JP2016510795A (enExample)
KR (2) KR20210099201A (enExample)
CN (2) CN110075098A (enExample)
AU (2) AU2014230096C1 (enExample)
BR (1) BR112015020209A2 (enExample)
CA (1) CA2903577C (enExample)
CL (1) CL2015002369A1 (enExample)
EA (1) EA037712B1 (enExample)
IL (1) IL240064A0 (enExample)
MX (2) MX2015011466A (enExample)
PH (1) PH12015502042B1 (enExample)
WO (1) WO2014140284A1 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2021530510A (ja) * 2018-07-17 2021-11-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 心臓に安全な抗糖尿病療法
JP2021530508A (ja) * 2018-07-17 2021-11-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 心臓および腎臓に安全な抗糖尿病療法
JP2022514045A (ja) * 2018-12-18 2022-02-09 武漢人福創新薬物研発中心有限公司 フェニルピロリジン化合物及びその用途
WO2022244846A1 (ja) * 2021-05-19 2022-11-24 Kagami株式会社 細胞増殖の調整のための組成物及び細胞増殖の調整方法

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US20200155558A1 (en) 2018-11-20 2020-05-21 Boehringer Ingelheim International Gmbh Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug
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US9968659B2 (en) 2016-03-04 2018-05-15 Novo Nordisk A/S Liraglutide in cardiovascular conditions
TW201733582A (zh) * 2016-03-28 2017-10-01 大日本住友製藥股份有限公司 Fxr促效劑及arb之組合醫藥
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Publication number Priority date Publication date Assignee Title
JP2021530510A (ja) * 2018-07-17 2021-11-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 心臓に安全な抗糖尿病療法
JP2021530508A (ja) * 2018-07-17 2021-11-11 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 心臓および腎臓に安全な抗糖尿病療法
JP2022514045A (ja) * 2018-12-18 2022-02-09 武漢人福創新薬物研発中心有限公司 フェニルピロリジン化合物及びその用途
JP7227380B2 (ja) 2018-12-18 2023-02-21 武漢人福創新薬物研発中心有限公司 フェニルピロリジン化合物及びその用途
WO2022244846A1 (ja) * 2021-05-19 2022-11-24 Kagami株式会社 細胞増殖の調整のための組成物及び細胞増殖の調整方法

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