JP2016510748A5 - - Google Patents

Download PDF

Info

Publication number
JP2016510748A5
JP2016510748A5 JP2015561618A JP2015561618A JP2016510748A5 JP 2016510748 A5 JP2016510748 A5 JP 2016510748A5 JP 2015561618 A JP2015561618 A JP 2015561618A JP 2015561618 A JP2015561618 A JP 2015561618A JP 2016510748 A5 JP2016510748 A5 JP 2016510748A5
Authority
JP
Japan
Prior art keywords
combination
cancer
alkyl
linear
inhibitor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015561618A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016510748A (ja
JP6835472B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2014/020858 external-priority patent/WO2014138279A1/en
Publication of JP2016510748A publication Critical patent/JP2016510748A/ja
Publication of JP2016510748A5 publication Critical patent/JP2016510748A5/ja
Application granted granted Critical
Publication of JP6835472B2 publication Critical patent/JP6835472B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015561618A 2013-03-05 2014-03-05 癌の処置のための組成物 Expired - Fee Related JP6835472B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361772885P 2013-03-05 2013-03-05
US61/772,885 2013-03-05
PCT/US2014/020858 WO2014138279A1 (en) 2013-03-05 2014-03-05 Compounds for treatment of cancer

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2019017755A Division JP2019077727A (ja) 2013-03-05 2019-02-04 癌の処置のための組成物

Publications (3)

Publication Number Publication Date
JP2016510748A JP2016510748A (ja) 2016-04-11
JP2016510748A5 true JP2016510748A5 (https=) 2017-04-06
JP6835472B2 JP6835472B2 (ja) 2021-02-24

Family

ID=51491914

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015561618A Expired - Fee Related JP6835472B2 (ja) 2013-03-05 2014-03-05 癌の処置のための組成物
JP2019017755A Pending JP2019077727A (ja) 2013-03-05 2019-02-04 癌の処置のための組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2019017755A Pending JP2019077727A (ja) 2013-03-05 2019-02-04 癌の処置のための組成物

Country Status (11)

Country Link
US (2) US10022356B2 (https=)
EP (1) EP2964028A4 (https=)
JP (2) JP6835472B2 (https=)
KR (1) KR102246652B1 (https=)
CN (2) CN105163584B (https=)
AU (2) AU2014225761B2 (https=)
CA (1) CA2904338C (https=)
IL (1) IL241232B (https=)
MX (2) MX375059B (https=)
RU (1) RU2708247C2 (https=)
WO (1) WO2014138279A1 (https=)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2010014066A (es) * 2008-06-16 2011-06-01 Univ Tennessee Res Foundation Compuestos para el tratamiento del cancer.
US9447049B2 (en) 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
US9029408B2 (en) * 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
US11084811B2 (en) 2010-03-01 2021-08-10 Oncternal Therapeutics, Inc. Compounds for treatment of cancer
CN105163584B (zh) * 2013-03-05 2019-06-04 田纳西大学研究基金会 用于治疗癌症的化合物
KR20170013891A (ko) 2014-05-06 2017-02-07 지티엑스, 인코포레이티드 암 치료용 화합물
CN104434924B (zh) * 2014-11-10 2016-09-14 暨南大学 曲美替尼在制备逆转肿瘤多药耐药性药物中的应用
CN107405348B (zh) * 2014-12-23 2021-06-11 点疗法-1公司 Raf抑制剂与紫杉烷的组合
WO2016130917A1 (en) * 2015-02-12 2016-08-18 Memorial Sloan Kettering Cancer Center Synergistic cancer treatment
IL256111B2 (en) * 2015-06-05 2023-09-01 Univ Illinois Treatment of pac combinations
AR105483A1 (es) 2015-06-30 2017-10-11 Exelixis Inc Sal de fumarato cristalina de (s)-[3,4-difluoro-2-(2-fluoro-4-yodofenilamino)fenil][3-hidroxi-3-(piperidin-2-il)azetidin-1-il]-metanona
WO2017007495A1 (en) * 2015-07-09 2017-01-12 The Jackson Laboratory Methods of treating cancer by administering a mek inhibitor in combination with a proteasome inhibitor
AU2016302344A1 (en) * 2015-08-06 2018-03-08 The Wistar Institute Of Anatomy And Biology Combination therapies targeting mitochondrial biogenesis for cancer therapy
US10821112B2 (en) 2016-03-16 2020-11-03 Dicerna Pharmaceuticals, Inc. Compositions and methods for the treatment of a beta-catenin-associated disease or disorder
WO2017200826A1 (en) * 2016-05-16 2017-11-23 Albert Einstein College Of Medicine, Inc. Assays and compounds for treatment of cancer
ES2928773T3 (es) 2017-01-17 2022-11-22 Heparegenix Gmbh Inhibidores de proteína cinasas para fomentar la regeneración hepática o reducir o prevenir la muerte de hepatocitos
US12339285B2 (en) 2017-03-10 2025-06-24 Konica Minolta, Inc. Method for estimating therapeutic efficacy
CN111655228B (zh) 2017-05-03 2024-02-09 听治疗有限责任公司 预防和治疗听力损失的组合物和方法
AU2018368453B2 (en) 2017-11-17 2024-05-30 The Board Of Trustees Of The University Of Illinois Cancer therapy by degrading dual MEK signaling
CN108218855A (zh) * 2018-03-12 2018-06-29 桑文军 一种新型微管蛋白抑制剂及其在抗肿瘤药物中的应用
MX2020012291A (es) * 2018-05-15 2021-03-25 Univ Tennessee Res Found Compuestos para el tratamiento de cancer de mama triple negativo y cancer de ovario.
KR20210021982A (ko) * 2018-05-15 2021-03-02 유니버시티 오브 테네시 리서치 파운데이션 췌장암 치료용 화합물
CA3114385A1 (en) 2018-10-05 2020-04-09 The Board Of Trustees Of The University Of Illinois Combination therapy for the treatment of uveal melanoma
GB201913124D0 (en) 2019-09-11 2019-10-23 Seald As Compositions and methods for treatment of cholangiocarcinoma
WO2021154929A1 (en) * 2020-01-31 2021-08-05 Verastem, Inc. Combination therapy for treating abnormal cell growth
CN113440616A (zh) * 2020-03-25 2021-09-28 上海科州药物研发有限公司 Ras或raf突变型癌症的联合疗法
US20230355581A1 (en) * 2020-07-02 2023-11-09 The Board of Regents of the Unversity of Texas System Methods of treatment for melanoma
WO2022067185A1 (en) * 2020-09-27 2022-03-31 Veru Inc. Methods of treating prostate cancer with minimal side effects
WO2022131667A1 (ko) * 2020-12-18 2022-06-23 경희대학교 산학협력단 Oligodendrocyte transcription factor 2 억제제를 유효성분으로 포함하는 흑색종 치료 효과 증진용 약학적 조성물
CN115504964A (zh) * 2022-04-12 2022-12-23 海创药业股份有限公司 氘代杂环酮类化合物及其用途
CN117143081B (zh) * 2022-05-24 2025-08-01 赣南医科大学 一种Sabizabulin的制备方法
WO2024036114A2 (en) * 2022-08-08 2024-02-15 The Regents Of The University Of California Combination therapy including cox-2 inhibitor for the treatment of cancer
WO2024186641A1 (en) * 2023-03-03 2024-09-12 Onconova Therapeutics, Inc. Methods and compositions for treating cancer
US20250032788A1 (en) * 2023-06-30 2025-01-30 Novocure Gmbh Compositions and methods for treating with a combination of alternating electric fields and dna-dependent protein kinase inhibitors
CN119409641A (zh) * 2024-11-05 2025-02-11 杭州电子科技大学 一种磺酰基衍生物和用途

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2074933C (en) 1990-11-30 2002-12-03 Masatoshi Chihiro Thiazole derivatives as active superoxide radical inhibitors
US5120749A (en) 1991-02-20 1992-06-09 Abbott Laboratories Platelet activating antagonists
JP2550915B2 (ja) 1994-06-21 1996-11-06 日本電気株式会社 印刷配線板の表面保護剤および表面保護膜の形成方法
WO2002050071A1 (en) 2000-12-21 2002-06-27 Bristol-Myers Squibb Company Thiazolyl inhibitors of tec family tyrosine kinases
US20040267017A1 (en) 2001-09-26 2004-12-30 Bierer Donald E 3-pyridyl or 4-isoquinolinyl thiazoles as c17, 20 lyase inhibitors
EP1432706A2 (en) 2001-09-26 2004-06-30 Bayer Pharmaceuticals Corporation 3-pyridyl or 4-isoquinolinyl thiazoles as c17,20 lyase inhibitors
FR2831536A1 (fr) 2001-10-26 2003-05-02 Aventis Pharma Sa Nouveaux derives de benzimidazoles, leur procede de preparation, leur application a titre de medicament, compositions pharmaceutiques et nouvelle utilisation notamment comme inhibiteurs de kdr
JP2005513026A (ja) 2001-11-15 2005-05-12 インサイト サン ディエゴ インコーポレイテッド 高コレステロール血症、異脂肪血症および他の代謝障害；癌、および他の疾患を治療するｎ−置換複素環
CA2514363A1 (en) 2003-02-12 2004-08-26 Transtech Pharma, Inc. Substituted azole derivatives as therapeutic agents
US7132440B2 (en) 2003-04-17 2006-11-07 Janssen Pharmaceutica, N.V. Substituted benzimidazoles and imidazo-[4,5]-pyridines
WO2004103960A2 (en) 2003-05-16 2004-12-02 Ambit Biosciences Corporation Compounds and uses thereof
JP2007513090A (ja) 2003-11-18 2007-05-24 ユニバーシティ オブ テネシー リサーチ ファウンデーション チアゾリジノンアミド、チアゾリジンカルボン酸アミド、その製造方法、およびその使用方法
AU2004298486A1 (en) 2003-12-12 2005-06-30 Wyeth Quinolines useful in treating cardiovascular disease
US20070191448A1 (en) 2004-03-08 2007-08-16 Robert Zelle Ion channel modulators
EP2298291A3 (en) 2004-06-18 2011-08-03 Agennix USA Inc. Kinase inhibitors for treating cancers
US7538113B2 (en) 2005-02-18 2009-05-26 Wyeth 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
UA95244C2 (ru) * 2005-06-22 2011-07-25 Плексикон, Инк. Соединения и способ модулирования активности киназ, и показания для их применения
US7612212B2 (en) * 2006-02-22 2009-11-03 Hoffmann-La Roche Inc. Substituted hydantoins
JPWO2007132867A1 (ja) * 2006-05-15 2009-09-24 杉本　芳一 癌の予防及び治療剤
US7464893B2 (en) * 2006-06-30 2008-12-16 Per Spjut Method of using a cord holder
KR100932093B1 (ko) 2006-09-27 2009-12-16 주식회사종근당 미세소관 형성 저해제로서 유용한 벤조페논 유도체
MX2010014066A (es) 2008-06-16 2011-06-01 Univ Tennessee Res Foundation Compuestos para el tratamiento del cancer.
US9447049B2 (en) * 2010-03-01 2016-09-20 University Of Tennessee Research Foundation Compounds for treatment of cancer
US8822513B2 (en) * 2010-03-01 2014-09-02 Gtx, Inc. Compounds for treatment of cancer
US9029408B2 (en) * 2008-06-16 2015-05-12 Gtx, Inc. Compounds for treatment of cancer
HUE067723T2 (hu) * 2009-10-16 2024-11-28 Novartis Ag MEK-inhibitort és B-Raf-inhibitort tartalmazó kombináció
JP5879273B2 (ja) * 2010-03-01 2016-03-08 ジーティーエックス・インコーポレイテッド 癌を処置するための化合物
US8426418B2 (en) 2010-08-27 2013-04-23 CollabRx Inc. Method to treat melanoma in BRAF inhibitor-resistant subjects
WO2012131909A1 (ja) 2011-03-29 2012-10-04 三菱電機株式会社 サーボ制御装置の異常診断装置および異常診断システム
WO2012135781A1 (en) 2011-04-01 2012-10-04 Genentech, Inc. Combinations of akt inhibitor compounds and chemotherapeutic agents, and methods of use
HUE026323T2 (en) * 2011-04-07 2016-05-30 Bayer Ip Gmbh Imidazopyridazines as akt kinase inhibitors
CN105163584B (zh) * 2013-03-05 2019-06-04 田纳西大学研究基金会 用于治疗癌症的化合物

Similar Documents

Publication Publication Date Title
JP2016510748A5 (https=)
RU2015142102A (ru) Соединение для лечения рака
JP6066421B2 (ja) 癌の治療のための低酸素活性化プロドラッグおよび血管新生阻害剤の投与方法
JP2009514880A5 (https=)
JP2009514881A5 (https=)
JP2013508288A5 (https=)
JP2013521281A5 (https=)
JP2018510851A5 (https=)
JP2013507415A5 (https=)
JP2018507191A5 (https=)
JP2016513137A5 (https=)
JP2010522194A5 (https=)
JP2014508811A5 (https=)
JP2016518437A5 (https=)
JP2013537203A5 (https=)
JP2017530984A5 (https=)
JP2016502544A5 (https=)
EA201690322A1 (ru) Терапевтически активные соединения и способы их применения
PH12012500504A1 (en) N-(4-((3-(2-amino-4-pyrimidinyl)-2-pyridinyl)oxy)phenyl)-4-(4-methyl-2-thienyl)-1-phthalazinamine in the treatment of antimitotic agent resistent cancer
JP2016503414A5 (https=)
JP2019529518A5 (https=)
JP2020502094A5 (https=)
JP2011521938A5 (https=)
JP2013538213A5 (https=)
JP2016513696A5 (https=)