JP2016509023A5 - - Google Patents
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- Publication number
- JP2016509023A5 JP2016509023A5 JP2015558092A JP2015558092A JP2016509023A5 JP 2016509023 A5 JP2016509023 A5 JP 2016509023A5 JP 2015558092 A JP2015558092 A JP 2015558092A JP 2015558092 A JP2015558092 A JP 2015558092A JP 2016509023 A5 JP2016509023 A5 JP 2016509023A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- polypeptide
- variant
- npp4
- npp1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2019135862A JP6944977B2 (ja) | 2013-02-13 | 2019-07-24 | 病的な石灰化および骨化を治療するための組成物および方法 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361764297P | 2013-02-13 | 2013-02-13 | |
| US61/764,297 | 2013-02-13 | ||
| US201361904786P | 2013-11-15 | 2013-11-15 | |
| US61/904,786 | 2013-11-15 | ||
| PCT/US2014/015945 WO2014126965A2 (en) | 2013-02-13 | 2014-02-12 | Compositions and methods for treating pathological calcification and ossification |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019135862A Division JP6944977B2 (ja) | 2013-02-13 | 2019-07-24 | 病的な石灰化および骨化を治療するための組成物および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016509023A JP2016509023A (ja) | 2016-03-24 |
| JP2016509023A5 true JP2016509023A5 (https=) | 2017-02-16 |
| JP6894664B2 JP6894664B2 (ja) | 2021-06-30 |
Family
ID=51354667
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015558092A Active JP6894664B2 (ja) | 2013-02-13 | 2014-02-12 | 病的な石灰化および骨化を治療するための組成物および方法 |
| JP2019135862A Active JP6944977B2 (ja) | 2013-02-13 | 2019-07-24 | 病的な石灰化および骨化を治療するための組成物および方法 |
| JP2021104071A Active JP7420766B2 (ja) | 2013-02-13 | 2021-06-23 | 病的な石灰化および骨化を治療するための組成物および方法 |
| JP2024002210A Pending JP2024026704A (ja) | 2013-02-13 | 2024-01-11 | 病的な石灰化および骨化を治療するための組成物および方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019135862A Active JP6944977B2 (ja) | 2013-02-13 | 2019-07-24 | 病的な石灰化および骨化を治療するための組成物および方法 |
| JP2021104071A Active JP7420766B2 (ja) | 2013-02-13 | 2021-06-23 | 病的な石灰化および骨化を治療するための組成物および方法 |
| JP2024002210A Pending JP2024026704A (ja) | 2013-02-13 | 2024-01-11 | 病的な石灰化および骨化を治療するための組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (7) | US9744219B2 (https=) |
| EP (2) | EP4523757A3 (https=) |
| JP (4) | JP6894664B2 (https=) |
| ES (1) | ES3014398T3 (https=) |
| PL (1) | PL2956163T3 (https=) |
| WO (1) | WO2014126965A2 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014126965A2 (en) * | 2013-02-13 | 2014-08-21 | Yale University | Compositions and methods for treating pathological calcification and ossification |
| EP3967755B1 (en) | 2014-12-19 | 2024-03-27 | Inozyme Pharma, Inc. | Soluble npp1 for use in a method for treating pseudoxanthoma elasticum |
| EP4414028A3 (en) | 2015-05-19 | 2024-11-27 | Yale University | Compositions for treating pathological calcification conditions, and methods using same |
| EP3377105A4 (en) | 2015-11-20 | 2019-04-24 | Yale University | COMPOSITIONS FOR THE TREATMENT OF ECTOPIC CALIBRATION DISORDERS AND METHODS THEREWITH |
| EP3471747A1 (en) | 2016-06-16 | 2019-04-24 | Alexion Pharmaceuticals, Inc. | Methods of treating myointimal proliferation |
| CA3032467A1 (en) * | 2016-08-05 | 2018-02-08 | Yale University | Compositions and methods for stroke prevention in pediatric sickle cell anemia patients |
| US12134790B2 (en) | 2017-09-27 | 2024-11-05 | Inozyme Pharma, Inc. | Methods of improving cardiovascular function and treating cardiovascular disease using a recombinant ectonucleotide pyrophosphatase phosphodiesterase (NPP1) |
| AU2019267545A1 (en) | 2018-05-08 | 2020-11-26 | Yale University | Compositions and methods for reducing progression of nephrolithiasis |
| CN120383683A (zh) * | 2018-08-31 | 2025-07-29 | 耶鲁大学 | Enpp1多肽及其使用方法 |
| WO2021252549A1 (en) | 2020-06-09 | 2021-12-16 | Inozyme Pharma, Inc. | Soluble enpp1 or enpp3 proteins and uses thereof |
| CA3184349A1 (en) * | 2020-07-02 | 2022-01-06 | Damon BANKS | Compositions and methods for treating allograft vasculopathy, moyamoya disease, moyamoya syndrome and intimal proliferation |
| CA3195071A1 (en) * | 2020-10-08 | 2022-04-14 | Inozyme Pharma, Inc. | Liver specific production of enpp1 or enpp3 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5023243A (en) | 1981-10-23 | 1991-06-11 | Molecular Biosystems, Inc. | Oligonucleotide therapeutic agent and method of making same |
| US5190931A (en) | 1983-10-20 | 1993-03-02 | The Research Foundation Of State University Of New York | Regulation of gene expression by employing translational inhibition of MRNA utilizing interfering complementary MRNA |
| US5225538A (en) | 1989-02-23 | 1993-07-06 | Genentech, Inc. | Lymphocyte homing receptor/immunoglobulin fusion proteins |
| US5168053A (en) | 1989-03-24 | 1992-12-01 | Yale University | Cleavage of targeted RNA by RNAase P |
| US6156501A (en) | 1993-10-26 | 2000-12-05 | Affymetrix, Inc. | Arrays of modified nucleic acid probes and methods of use |
| WO1995019570A1 (en) | 1994-01-14 | 1995-07-20 | Genentech, Inc. | Antagonists to insulin receptor tyrosine kinase inhibitor |
| US6043056A (en) | 1998-11-06 | 2000-03-28 | Incyte Pharmaceuticals, Inc. | Cell surface glycoproteins |
| US6521645B2 (en) | 2000-11-20 | 2003-02-18 | The University Of Kansas Medical Center | Methods for the treatment and prevention of urinary stone disease |
| US7888372B2 (en) | 2001-03-23 | 2011-02-15 | National Institutes Of Health (Nih) | Compositions and methods for modulating bone mineral deposition |
| US20020183276A1 (en) * | 2001-03-23 | 2002-12-05 | Burnham Institute | Compositions and methods for modulating bone mineral deposition |
| US20030191073A1 (en) | 2001-11-07 | 2003-10-09 | Challita-Eid Pia M. | Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer |
| AU2002324700A1 (en) | 2001-08-14 | 2003-03-03 | Bayer Ag | Nucleic acid and amino acid sequences involved in pain |
| JP4200100B2 (ja) | 2001-11-07 | 2008-12-24 | アジェンシス，インコーポレイテッド | 癌の処置および検出において有用な１６１ｐ２ｆ１０ｂと称される、核酸および対応タンパク質 |
| WO2003072593A2 (en) | 2002-02-21 | 2003-09-04 | University Of Virginia Patent Foundation | Bone targeting peptides |
| JP5199077B2 (ja) | 2005-06-10 | 2013-05-15 | アルタス ファーマシューティカルズ インコーポレイテッド | シュウ酸オキシダーゼ結晶の投与による、シュウ酸塩濃度を低下させるための方法 |
| WO2008105911A2 (en) | 2006-08-02 | 2008-09-04 | Altus Pharmaceuticals Inc. | Crystallized oxalate decarboxylase and methods of use |
| WO2009030254A1 (en) | 2007-09-04 | 2009-03-12 | Curevac Gmbh | Complexes of rna and cationic peptides for transfection and for immunostimulation |
| GB0803352D0 (en) | 2008-02-22 | 2008-04-02 | Ntnu Technology Transfer As | Oligopeptidic compounds and uses thereof |
| US8846603B2 (en) | 2010-03-12 | 2014-09-30 | Synageva Biopharma Corp. | NPP1 fusion proteins |
| RU2601154C2 (ru) | 2011-03-11 | 2016-10-27 | Синаджива Байофарма Корп | Гибридные белки npp1 |
| WO2014126965A2 (en) * | 2013-02-13 | 2014-08-21 | Yale University | Compositions and methods for treating pathological calcification and ossification |
| EP3967755B1 (en) * | 2014-12-19 | 2024-03-27 | Inozyme Pharma, Inc. | Soluble npp1 for use in a method for treating pseudoxanthoma elasticum |
| EP4414028A3 (en) | 2015-05-19 | 2024-11-27 | Yale University | Compositions for treating pathological calcification conditions, and methods using same |
-
2014
- 2014-02-12 WO PCT/US2014/015945 patent/WO2014126965A2/en not_active Ceased
- 2014-02-12 EP EP24215211.4A patent/EP4523757A3/en active Pending
- 2014-02-12 ES ES14751154T patent/ES3014398T3/es active Active
- 2014-02-12 EP EP14751154.7A patent/EP2956163B1/en active Active
- 2014-02-12 JP JP2015558092A patent/JP6894664B2/ja active Active
- 2014-02-12 PL PL14751154.7T patent/PL2956163T3/pl unknown
- 2014-02-12 US US14/765,514 patent/US9744219B2/en active Active
-
2017
- 2017-03-22 US US15/466,401 patent/US9913881B2/en active Active
- 2017-08-08 US US15/671,287 patent/US20170333533A1/en not_active Abandoned
- 2017-08-25 US US15/686,972 patent/US10052367B2/en active Active
-
2018
- 2018-07-12 US US16/033,948 patent/US10624958B2/en active Active
-
2019
- 2019-07-24 JP JP2019135862A patent/JP6944977B2/ja active Active
-
2020
- 2020-03-09 US US16/813,315 patent/US11266722B2/en active Active
-
2021
- 2021-06-23 JP JP2021104071A patent/JP7420766B2/ja active Active
-
2022
- 2022-01-28 US US17/587,253 patent/US12589137B2/en active Active
-
2024
- 2024-01-11 JP JP2024002210A patent/JP2024026704A/ja active Pending
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