JP2016506387A5 - - Google Patents
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- Publication number
- JP2016506387A5 JP2016506387A5 JP2015545840A JP2015545840A JP2016506387A5 JP 2016506387 A5 JP2016506387 A5 JP 2016506387A5 JP 2015545840 A JP2015545840 A JP 2015545840A JP 2015545840 A JP2015545840 A JP 2015545840A JP 2016506387 A5 JP2016506387 A5 JP 2016506387A5
- Authority
- JP
- Japan
- Prior art keywords
- phenyl
- optionally substituted
- carboxylic acid
- amide
- dioxin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 0 CC*c1cc(*)c(*)c(*)c1* Chemical compound CC*c1cc(*)c(*)c(*)c1* 0.000 description 3
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261734184P | 2012-12-06 | 2012-12-06 | |
| US61/734,184 | 2012-12-06 | ||
| PCT/US2013/073319 WO2014089296A2 (en) | 2012-12-06 | 2013-12-05 | Functionalized benzamide derivatives as antiviral agents against hbv infection |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018109976A Division JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016506387A JP2016506387A (ja) | 2016-03-03 |
| JP2016506387A5 true JP2016506387A5 (en:Method) | 2016-07-21 |
| JP6353460B2 JP6353460B2 (ja) | 2018-07-04 |
Family
ID=50884140
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545840A Expired - Fee Related JP6353460B2 (ja) | 2012-12-06 | 2013-12-05 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
| JP2018109976A Pending JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018109976A Pending JP2018162272A (ja) | 2012-12-06 | 2018-06-08 | Ｈｂｖ感染に対する抗ウイルス剤としての官能化ベンズアミド誘導体 |
Country Status (13)
| Country | Link |
|---|---|
| US (2) | US20150307443A1 (en:Method) |
| EP (1) | EP2928459A4 (en:Method) |
| JP (2) | JP6353460B2 (en:Method) |
| KR (1) | KR20150090219A (en:Method) |
| CN (2) | CN104918612B (en:Method) |
| AU (2) | AU2013355220B2 (en:Method) |
| BR (1) | BR112015013121A2 (en:Method) |
| CA (1) | CA2892606A1 (en:Method) |
| IL (1) | IL238930B (en:Method) |
| NZ (2) | NZ708392A (en:Method) |
| PH (1) | PH12015501276A1 (en:Method) |
| SG (2) | SG11201503997VA (en:Method) |
| WO (1) | WO2014089296A2 (en:Method) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6409001B2 (ja) * | 2012-12-27 | 2018-10-17 | ドレクセル ユニバーシティ | Ｈｂｖ感染に対する新規抗ウイルス剤 |
| KR102363174B1 (ko) | 2014-03-13 | 2022-02-15 | 인디애나 유니버시티 리서치 앤드 테크놀로지 코포레이션 | B형 간염 코어 단백질 알로스테릭 조정제 |
| JP6462155B2 (ja) * | 2015-05-04 | 2019-01-30 | エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ | Ｂ型肝炎ウイルス感染症の治療用のＨＢｓＡｇ（ＨＢＶ表面抗原）及びＨＢＶ ＤＮＡ産生の阻害剤としてのテトラヒドロピリドピリミジン類及びテトラヒドロピリドピリジン類 |
| TWI786639B (zh) | 2015-09-15 | 2022-12-11 | 美商艾森伯利生物科學公司 | B型肝炎核心蛋白質調節劑 |
| WO2018039131A1 (en) | 2016-08-22 | 2018-03-01 | Protiva Biotherapeutics, Inc. | Anti-pd-1 antibodies, or fragments thereof, for treating hepatitis b |
| JOP20190024A1 (ar) | 2016-08-26 | 2019-02-19 | Gilead Sciences Inc | مركبات بيروليزين بها استبدال واستخداماتها |
| CA3036245C (en) | 2016-09-13 | 2021-07-20 | Arbutus Biopharma Corporation | Substituted chromane-8-carboxamide compounds and analogues thereof, and methods using same |
| CN109937201A (zh) | 2016-09-15 | 2019-06-25 | 组装生物科学股份有限公司 | 乙型肝炎核心蛋白调节剂 |
| US10821103B2 (en) | 2016-11-07 | 2020-11-03 | Arbutus Biopharma Corporation | Substituted pyridinone-containing trycyclic compounds, and methods using same |
| WO2018160878A1 (en) | 2017-03-02 | 2018-09-07 | Assembly Biosciences, Inc. | Cyclic sulfamide compounds and methods of using same |
| CA3056886A1 (en) | 2017-03-21 | 2018-09-27 | Arbutus Biopharma Corporation | Substituted dihydroindene-4-carboxamides and analogs thereof, and methods using same |
| JP7050165B2 (ja) | 2018-02-26 | 2022-04-07 | ギリアード サイエンシーズ， インコーポレイテッド | Ｈｂｖ複製阻害剤としての置換ピロリジン化合物 |
| CN112724037B (zh) * | 2018-06-13 | 2022-03-11 | 浙江大学 | 一种羟苯水杨胺羟基化物、制备方法及其应用 |
| TWI826492B (zh) | 2018-07-27 | 2023-12-21 | 加拿大商愛彼特生物製藥公司 | 經取代四氫環戊[c]吡咯、經取代二氫吡咯，其類似物及使用其之方法 |
| SG11202104086PA (en) | 2018-10-22 | 2021-05-28 | Assembly Biosciences Inc | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2020087107A1 (en) | 2018-10-31 | 2020-05-07 | The University Of Sydney | Compositions and methods for treating viral infections |
| TW202415643A (zh) | 2018-12-12 | 2024-04-16 | 加拿大商愛彼特生物製藥公司 | 經取代之芳基甲基脲類及雜芳基甲基脲類、其類似物及其使用方法 |
| MX2021014379A (es) | 2019-05-24 | 2022-01-06 | Assembly Biosciences Inc | Composiciones farmaceuticas para el tratamiento de hbv. |
| KR20220119052A (ko) | 2019-12-20 | 2022-08-26 | 아뷰터스 바이오파마 코포레이션 | 합성 공정 및 중간체 |
| WO2021216656A1 (en) | 2020-04-22 | 2021-10-28 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2021216661A1 (en) | 2020-04-22 | 2021-10-28 | Assembly Biosciences, Inc. | Pyrazole carboxamide compounds for treatment of hbv |
| CN115916341A (zh) | 2020-04-22 | 2023-04-04 | 组装生物科学股份有限公司 | 用于治疗hbv的吡唑甲酰胺化合物 |
| WO2021216660A1 (en) | 2020-04-22 | 2021-10-28 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| US20210371388A1 (en) * | 2020-05-12 | 2021-12-02 | Baruch S. Blumberg Institute | Bicyclic Carboxamide with Exocyclic Urea Derivatives as Antivirals for the Treatment of HBV Infection |
| TW202214574A (zh) * | 2020-06-08 | 2022-04-16 | 加拿大商愛彼特生物製藥公司 | 經取代之(呔-1-基甲基)脲類、經取代之n-(呔-1-基甲基)醯胺類及其類似物 |
| WO2023069547A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023069545A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023069544A1 (en) | 2021-10-20 | 2023-04-27 | Assembly Biosciences, Inc. | 5-membered heteroaryl carboxamide compounds for treatment of hbv |
| WO2023164183A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164179A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164181A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| WO2023164186A1 (en) | 2022-02-25 | 2023-08-31 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
| EP4635523A1 (en) | 2022-12-14 | 2025-10-22 | Maruemu Works Co., Ltd. | Base material for screw, screw, and method for producing same |
| WO2025043094A1 (en) | 2023-08-23 | 2025-02-27 | Assembly Biosciences, Inc. | Benzothia(dia)zepine compounds for treatment of hbv and hdv |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL108459A0 (en) * | 1993-02-05 | 1994-04-12 | Opjohn Company | 4-Hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl [B] pyran-2-ones useful for treating infections due to hiv and other retroviruses |
| JPH06297860A (ja) * | 1993-04-14 | 1994-10-25 | New Oji Paper Co Ltd | 感熱記録体 |
| AU9318298A (en) * | 1997-11-14 | 1999-06-07 | Warner-Lambert Company | Small molecule intervention in hiv-1 replication |
| AU2160899A (en) * | 1997-12-11 | 1999-06-28 | Janssen Pharmaceutica N.V. | Retinoic acid mimetic anilides |
| US6653309B1 (en) * | 1999-04-26 | 2003-11-25 | Vertex Pharmaceuticals Incorporated | Inhibitors of IMPDH enzyme technical field of the invention |
| WO2002000613A2 (en) * | 2000-06-27 | 2002-01-03 | Axxima Pharmaceuticals Ag | Inhibitors of hepatitis b virus infection |
| DE10109856A1 (de) * | 2001-03-01 | 2002-09-05 | Bayer Ag | Arzneimittel gegen virale Erkrankungen |
| JP3714948B2 (ja) * | 2002-09-11 | 2005-11-09 | 呉羽化学工業株式会社 | アミン化合物及びその用途 |
| US7696244B2 (en) * | 2003-05-16 | 2010-04-13 | The Regents Of The University Of California | Compounds having activity in increasing ion transport by mutant-CFTR and uses thereof |
| SE0401342D0 (sv) * | 2004-05-25 | 2004-05-25 | Astrazeneca Ab | Therapeutic compounds |
| WO2007047646A2 (en) * | 2005-10-14 | 2007-04-26 | Janssen Pharmaceutica, N.V. | Substituted dihydro-isoindolones useful in treating kinase disorders |
| CN1951932B (zh) * | 2005-10-20 | 2010-11-24 | 北京科莱博医药开发有限责任公司 | [n-(3',4'亚甲二氧基)苯基乙基]甲酰胺基苯甲酸衍生物,它们的制备方法及其用途 |
| HUE025173T2 (hu) * | 2005-12-13 | 2016-01-28 | Incyte Corp | Heteroaril-szubsztituált pirrollo[2,3-b]piridinek és pirrolo[2,3-b]pirimidinek mint Janus-kináz inhibitorok |
| WO2007143557A2 (en) * | 2006-06-02 | 2007-12-13 | Brandeis University | Compounds and methods for treating mammalian gastrointestinal parasitic infections |
| DE102006060598A1 (de) * | 2006-12-21 | 2008-06-26 | Merck Patent Gmbh | Tetrahydrobenzoisoxazole |
| JP5746860B2 (ja) * | 2007-04-09 | 2015-07-08 | メチルジーン インコーポレイテッド | ヒストンデアセチラーゼ阻害剤 |
| WO2009083224A1 (en) * | 2007-12-27 | 2009-07-09 | F. Hoffmann-La Roche Ag | Insulin-degrading enzyme crystals |
| EA024853B1 (ru) * | 2008-12-03 | 2016-10-31 | Пресидио Фармасьютикалс, Инк. | Ингибиторы ns5a вгс |
| EP2377850A1 (en) * | 2010-03-30 | 2011-10-19 | Pharmeste S.r.l. | TRPV1 vanilloid receptor antagonists with a bicyclic portion |
| WO2012058378A1 (en) * | 2010-10-29 | 2012-05-03 | Romark Laboratories L.C. | Pharmaceutical compositions and methods of use of salicylanilides for treatment of hepatitis viruses |
| US20140005235A1 (en) * | 2011-03-22 | 2014-01-02 | Syngenta Participations Ag | Insecticidal compounds |
| US9616064B2 (en) * | 2011-03-30 | 2017-04-11 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Rho kinase inhibitors and methods of use |
-
2013
- 2013-12-05 WO PCT/US2013/073319 patent/WO2014089296A2/en not_active Ceased
- 2013-12-05 SG SG11201503997VA patent/SG11201503997VA/en unknown
- 2013-12-05 SG SG10201900695PA patent/SG10201900695PA/en unknown
- 2013-12-05 US US14/650,159 patent/US20150307443A1/en not_active Abandoned
- 2013-12-05 NZ NZ708392A patent/NZ708392A/en not_active IP Right Cessation
- 2013-12-05 EP EP13859675.4A patent/EP2928459A4/en not_active Withdrawn
- 2013-12-05 NZ NZ748966A patent/NZ748966A/en not_active IP Right Cessation
- 2013-12-05 CA CA2892606A patent/CA2892606A1/en not_active Abandoned
- 2013-12-05 CN CN201380065824.0A patent/CN104918612B/zh not_active Expired - Fee Related
- 2013-12-05 CN CN201910903071.5A patent/CN110642741A/zh active Pending
- 2013-12-05 JP JP2015545840A patent/JP6353460B2/ja not_active Expired - Fee Related
- 2013-12-05 AU AU2013355220A patent/AU2013355220B2/en not_active Ceased
- 2013-12-05 BR BR112015013121A patent/BR112015013121A2/pt not_active IP Right Cessation
- 2013-12-05 KR KR1020157017223A patent/KR20150090219A/ko not_active Ceased
-
2015
- 2015-05-20 IL IL238930A patent/IL238930B/en not_active IP Right Cessation
- 2015-06-05 PH PH12015501276A patent/PH12015501276A1/en unknown
-
2018
- 2018-06-08 JP JP2018109976A patent/JP2018162272A/ja active Pending
- 2018-11-01 AU AU2018256602A patent/AU2018256602A1/en not_active Abandoned
- 2018-11-28 US US16/202,822 patent/US20190092720A1/en not_active Abandoned