JP2016504362A - アルブミンおよびパクリタキセルのナノ粒子組成物 - Google Patents

アルブミンおよびパクリタキセルのナノ粒子組成物 Download PDF

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Publication number
JP2016504362A
JP2016504362A JP2015550675A JP2015550675A JP2016504362A JP 2016504362 A JP2016504362 A JP 2016504362A JP 2015550675 A JP2015550675 A JP 2015550675A JP 2015550675 A JP2015550675 A JP 2015550675A JP 2016504362 A JP2016504362 A JP 2016504362A
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composition
albumin
paclitaxel
less
nanoparticles
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Pending
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JP2015550675A
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English (en)
Japanese (ja)
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JP2016504362A5 (cg-RX-API-DMAC7.html
Inventor
ニール ピー． デサイ，
ニール ピー． デサイ，
Original Assignee
アブラクシス バイオサイエンス， エルエルシー
アブラクシス バイオサイエンス， エルエルシー
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Application filed by アブラクシス バイオサイエンス， エルエルシー, アブラクシス バイオサイエンス， エルエルシー filed Critical アブラクシス バイオサイエンス， エルエルシー
Publication of JP2016504362A publication Critical patent/JP2016504362A/ja
Publication of JP2016504362A5 publication Critical patent/JP2016504362A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Oncology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
JP2015550675A 2012-12-28 2013-12-19 アルブミンおよびパクリタキセルのナノ粒子組成物 Pending JP2016504362A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261747123P 2012-12-28 2012-12-28
US61/747,123 2012-12-28
US13/794,705 US20140186447A1 (en) 2012-12-28 2013-03-11 Nanoparticle compositions of albumin and paclitaxel
US13/794,705 2013-03-11
PCT/US2013/076630 WO2014105644A1 (en) 2012-12-28 2013-12-19 Nanoparticle compositions of albumin and paclitaxel

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2018030637A Division JP2018087241A (ja) 2012-12-28 2018-02-23 アルブミンおよびパクリタキセルのナノ粒子組成物

Publications (2)

Publication Number Publication Date
JP2016504362A true JP2016504362A (ja) 2016-02-12
JP2016504362A5 JP2016504362A5 (cg-RX-API-DMAC7.html) 2017-02-02

Family

ID=51017455

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015550675A Pending JP2016504362A (ja) 2012-12-28 2013-12-19 アルブミンおよびパクリタキセルのナノ粒子組成物
JP2018030637A Pending JP2018087241A (ja) 2012-12-28 2018-02-23 アルブミンおよびパクリタキセルのナノ粒子組成物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2018030637A Pending JP2018087241A (ja) 2012-12-28 2018-02-23 アルブミンおよびパクリタキセルのナノ粒子組成物

Country Status (19)

Country Link
US (2) US20140186447A1 (cg-RX-API-DMAC7.html)
EP (1) EP2938340A4 (cg-RX-API-DMAC7.html)
JP (2) JP2016504362A (cg-RX-API-DMAC7.html)
KR (1) KR20150100903A (cg-RX-API-DMAC7.html)
CN (1) CN105007912A (cg-RX-API-DMAC7.html)
AU (1) AU2013370955B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015015319A2 (cg-RX-API-DMAC7.html)
CA (1) CA2896288A1 (cg-RX-API-DMAC7.html)
CR (1) CR20150386A (cg-RX-API-DMAC7.html)
HK (1) HK1216611A1 (cg-RX-API-DMAC7.html)
IL (1) IL239593A0 (cg-RX-API-DMAC7.html)
MX (1) MX2015008361A (cg-RX-API-DMAC7.html)
NI (1) NI201500090A (cg-RX-API-DMAC7.html)
NZ (1) NZ630912A (cg-RX-API-DMAC7.html)
PH (1) PH12015501486B1 (cg-RX-API-DMAC7.html)
RU (1) RU2663687C2 (cg-RX-API-DMAC7.html)
SG (1) SG11201505111TA (cg-RX-API-DMAC7.html)
WO (1) WO2014105644A1 (cg-RX-API-DMAC7.html)
ZA (1) ZA201504762B (cg-RX-API-DMAC7.html)

Cited By (4)

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JP2020536052A (ja) * 2017-10-03 2020-12-10 クリティテック・インコーポレイテッド 癌の治療のための免疫療法剤の全身送達と組み合わせた抗腫瘍粒子の局所送達
JP2022553426A (ja) * 2019-10-28 2022-12-22 アブラクシス バイオサイエンス， エルエルシー アルブミンおよびラパマイシンの医薬組成物
JP2024540366A (ja) * 2021-11-03 2024-10-31 エスエヌ バイオサイエンス インコーポレイテッド 粒度分布維持安定性が改善されたアルブミン結合タキサンナノ粒子の製造方法
JP7792750B2 (ja) 2017-10-03 2025-12-26 クリティテック・インコーポレイテッド 癌の治療のための免疫療法剤の全身送達と組み合わせた抗腫瘍粒子の局所送達

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AU2008260447B2 (en) * 2007-06-01 2013-10-10 Abraxis Bioscience, Llc Methods and compositions for treating recurrent cancer
KR20120044279A (ko) 2009-04-15 2012-05-07 아브락시스 바이오사이언스, 엘엘씨 무-프리온 나노입자 조성물 및 방법
BR112012024349A2 (pt) 2010-03-26 2016-05-24 Abraxis Bioscience Llc métodos de tratamento de carcinoma hepatocelular
CN105147613A (zh) 2010-03-29 2015-12-16 阿布拉科斯生物科学有限公司 增强药物递送和治疗剂有效性的方法
RU2016119999A (ru) 2010-03-29 2018-11-08 АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи Способы лечения онкологических заболеваний
EP2575804A4 (en) 2010-06-04 2013-10-23 Abraxis Bioscience Llc METHOD FOR THE TREATMENT OF PANCREASCRE
WO2012149451A1 (en) 2011-04-28 2012-11-01 Abraxis Bioscience, Llc Intravascular delivery of nanoparticle compositions and uses thereof
EP2707030B1 (en) 2011-05-09 2020-02-19 Mayo Foundation For Medical Education And Research Cancer treatments
RU2705998C2 (ru) 2011-12-14 2019-11-13 АБРАКСИС БАЙОСАЙЕНС, ЭлЭлСи Применение полимерных эксципиентов для лиофилизации или заморозки частиц
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ES2804323T3 (es) 2013-03-12 2021-02-05 Abraxis Bioscience Llc Procedimientos de tratamiento de cáncer de pulmón
CN105246468A (zh) 2013-03-14 2016-01-13 阿布拉科斯生物科学有限公司 治疗膀胱癌的方法
KR102245421B1 (ko) 2013-05-30 2021-04-29 큐라디즘 약학적 조성물, 이의 제조방법 및 이의 용도
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CN104224750A (zh) * 2014-09-17 2014-12-24 四川大学 一种注射用卡巴他赛白蛋白纳米粒制剂及其制备方法
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MX388073B (es) 2014-11-25 2025-03-19 Nanobiotix Composición farmacéutica, preparación y usos de la misma.
TW201628644A (zh) * 2014-11-25 2016-08-16 奈諾生技公司 醫藥組合物、其製備及其用途
DK3229776T3 (da) 2014-11-25 2023-07-31 Curadigm Sas Farmaceutisk sammensætning, der kombinerer mindst to særskilte nanopartikler og en farmaceutisk forbindelse, fremstilling og anvendelser deraf
HUE056175T2 (hu) 2014-11-25 2022-01-28 Curadigm Sas Gyógyászati készítmények, elõállításuk és alkalmazásaik
US10705070B1 (en) 2015-03-05 2020-07-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug
US10527604B1 (en) * 2015-03-05 2020-01-07 Abraxis Bioscience, Llc Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel
MA43100A (fr) 2015-05-28 2018-09-05 Nanobiotix Nanoparticules à utiliser en tant que vaccin thérapeutique
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TW201707725A (zh) 2015-08-18 2017-03-01 美國馬友醫藥教育研究基金會 載體－抗體組合物及其製造及使用方法
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KR102462041B1 (ko) 2016-09-01 2022-11-02 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 암 치료용 담체－ｐｄ－ｌ１ 결합제 조성물
JP7025412B2 (ja) 2016-09-06 2022-02-24 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチ パクリタキセル－アルブミン－結合剤組成物並びに該組成物の使用及び製造方法
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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020536052A (ja) * 2017-10-03 2020-12-10 クリティテック・インコーポレイテッド 癌の治療のための免疫療法剤の全身送達と組み合わせた抗腫瘍粒子の局所送達
JP7792750B2 (ja) 2017-10-03 2025-12-26 クリティテック・インコーポレイテッド 癌の治療のための免疫療法剤の全身送達と組み合わせた抗腫瘍粒子の局所送達
JP2022553426A (ja) * 2019-10-28 2022-12-22 アブラクシス バイオサイエンス， エルエルシー アルブミンおよびラパマイシンの医薬組成物
JP2024540366A (ja) * 2021-11-03 2024-10-31 エスエヌ バイオサイエンス インコーポレイテッド 粒度分布維持安定性が改善されたアルブミン結合タキサンナノ粒子の製造方法
JP7786770B2 (ja) 2021-11-03 2025-12-16 エスエヌ バイオサイエンス インコーポレイテッド 粒度分布維持安定性が改善されたアルブミン結合タキサンナノ粒子の製造方法

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MX2015008361A (es) 2016-03-11
RU2663687C2 (ru) 2018-08-08
JP2018087241A (ja) 2018-06-07
ZA201504762B (en) 2016-10-26
AU2013370955B2 (en) 2018-12-06
US20140186447A1 (en) 2014-07-03
NZ630912A (en) 2017-05-26
CA2896288A1 (en) 2014-07-03
IL239593A0 (en) 2015-08-31
RU2015131141A (ru) 2017-02-03
SG11201505111TA (en) 2015-07-30
CN105007912A (zh) 2015-10-28
PH12015501486B1 (en) 2020-12-16
CR20150386A (es) 2015-10-07
EP2938340A1 (en) 2015-11-04
WO2014105644A1 (en) 2014-07-03
US20190192477A1 (en) 2019-06-27
EP2938340A4 (en) 2016-08-03
KR20150100903A (ko) 2015-09-02
NI201500090A (es) 2015-12-22
PH12015501486A1 (en) 2015-09-21
AU2013370955A1 (en) 2015-07-16
HK1216611A1 (zh) 2016-11-25
BR112015015319A2 (pt) 2017-07-11

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