JP2016502558A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2016502558A5 JP2016502558A5 JP2015546050A JP2015546050A JP2016502558A5 JP 2016502558 A5 JP2016502558 A5 JP 2016502558A5 JP 2015546050 A JP2015546050 A JP 2015546050A JP 2015546050 A JP2015546050 A JP 2015546050A JP 2016502558 A5 JP2016502558 A5 JP 2016502558A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- seq
- protein
- set composition
- polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 17
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 229920000249 biocompatible polymer Polymers 0.000 claims 3
- 229920001282 polysaccharide Polymers 0.000 claims 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 2
- 229920001661 Chitosan Polymers 0.000 claims 2
- 229920002307 Dextran Polymers 0.000 claims 2
- 229960002086 dextran Drugs 0.000 claims 2
- 229960000633 dextran sulfate Drugs 0.000 claims 2
- 229920002674 hyaluronan Polymers 0.000 claims 2
- 229960003160 hyaluronic acid Drugs 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 239000002105 nanoparticle Substances 0.000 claims 2
- 229920001983 poloxamer Polymers 0.000 claims 2
- 229920000642 polymer Polymers 0.000 claims 2
- IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 claims 1
- 241001070941 Castanea Species 0.000 claims 1
- 235000014036 Castanea Nutrition 0.000 claims 1
- 102000008186 Collagen Human genes 0.000 claims 1
- 108010035532 Collagen Proteins 0.000 claims 1
- 102000009123 Fibrin Human genes 0.000 claims 1
- 108010073385 Fibrin Proteins 0.000 claims 1
- BWGVNKXGVNDBDI-UHFFFAOYSA-N Fibrin monomer Chemical compound CNC(=O)CNC(=O)CN BWGVNKXGVNDBDI-UHFFFAOYSA-N 0.000 claims 1
- RVGRUAULSDPKGF-UHFFFAOYSA-N Poloxamer Chemical compound C1CO1.CC1CO1 RVGRUAULSDPKGF-UHFFFAOYSA-N 0.000 claims 1
- 229920001710 Polyorthoester Polymers 0.000 claims 1
- 229920002000 Xyloglucan Polymers 0.000 claims 1
- 125000002057 carboxymethyl group Chemical group [H]OC(=O)C([H])([H])[*] 0.000 claims 1
- 229920001436 collagen Polymers 0.000 claims 1
- 125000004093 cyano group Chemical group *C#N 0.000 claims 1
- 229950003499 fibrin Drugs 0.000 claims 1
- 230000001939 inductive effect Effects 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 239000000787 lecithin Substances 0.000 claims 1
- 229940067606 lecithin Drugs 0.000 claims 1
- 235000010445 lecithin Nutrition 0.000 claims 1
- 229960000502 poloxamer Drugs 0.000 claims 1
- 239000002745 poly(ortho ester) Substances 0.000 claims 1
- 108010054442 polyalanine Proteins 0.000 claims 1
- 229920001610 polycaprolactone Polymers 0.000 claims 1
- 229920001223 polyethylene glycol Polymers 0.000 claims 1
- 230000036573 scar formation Effects 0.000 claims 1
- 230000000699 topical effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12196007.4 | 2012-12-07 | ||
| EP12196007.4A EP2740485B1 (en) | 2012-12-07 | 2012-12-07 | Protein slurp-1 for use in the treatment of ocular diseases |
| PCT/EP2013/075981 WO2014087022A1 (en) | 2012-12-07 | 2013-12-09 | Protein slurp-1 for use in the treatment of ocular diseases |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016502558A JP2016502558A (ja) | 2016-01-28 |
| JP2016502558A5 true JP2016502558A5 (https=) | 2017-01-19 |
| JP6335188B2 JP6335188B2 (ja) | 2018-05-30 |
Family
ID=47297008
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015546050A Expired - Fee Related JP6335188B2 (ja) | 2012-12-07 | 2013-12-09 | 眼疾患の治療における使用のためのタンパク質ｓｌｕｒｐ−１ |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10098925B2 (https=) |
| EP (1) | EP2740485B1 (https=) |
| JP (1) | JP6335188B2 (https=) |
| KR (1) | KR20150108351A (https=) |
| CN (1) | CN105188731B (https=) |
| AU (1) | AU2013353957B2 (https=) |
| BR (1) | BR112015013215A2 (https=) |
| CA (1) | CA2891201A1 (https=) |
| CL (1) | CL2015001520A1 (https=) |
| EA (1) | EA201591095A1 (https=) |
| IL (1) | IL239078A0 (https=) |
| MX (1) | MX2015006779A (https=) |
| SG (2) | SG10201705592YA (https=) |
| WO (1) | WO2014087022A1 (https=) |
| ZA (1) | ZA201503747B (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2740485B1 (en) * | 2012-12-07 | 2018-10-31 | Brightpulse Holding LTD. | Protein slurp-1 for use in the treatment of ocular diseases |
| EP3689327B1 (fr) * | 2019-01-24 | 2025-03-12 | Organes Tissus Régénération Réparation Remplacement | Composition pharmaceutique dans le traitement de lésions pulmonaires |
| CN114601915B (zh) * | 2022-03-25 | 2023-04-07 | 四川大学华西医院 | Slurp1蛋白在制备预防或治疗皮肤弹性纤维疾病的药物中的用途 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1257184B (it) | 1992-12-22 | 1996-01-10 | Applied Research Systems | Preparato ad attivita' antinfiammatoria, anticoagulante e antitumorale |
| AU2004229237B2 (en) * | 2003-04-16 | 2009-06-04 | Merck Serono Sa | Use of SLURP-1 for treating diseases related to acetylcholine receptors dysfunction |
| US20100303788A1 (en) * | 2009-05-29 | 2010-12-02 | Allergan, Inc. | Methods of Treating Chronic Neurogenic Inflammation Using Galanin Retargeted Endopepidases |
| CA2806143A1 (en) * | 2010-07-30 | 2012-02-02 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mb H | Drug delivery devices and growth factor formulations for accelerated wound healing |
| EP3848055A1 (en) * | 2011-06-03 | 2021-07-14 | Ophidion Inc. | Compositions and methods for transport across the blood brain barrier |
| US9132193B2 (en) * | 2012-11-05 | 2015-09-15 | University of Pittsburgh—of the Commonwealth System of Higher Education | Use of Slurp1 as an imunomodulatory molecule in the ocular surface |
| CA2890424C (en) * | 2012-11-08 | 2020-11-17 | Yamaguchi University | Therapeutic agent for keratoconjunctive disorders |
| EP2740485B1 (en) * | 2012-12-07 | 2018-10-31 | Brightpulse Holding LTD. | Protein slurp-1 for use in the treatment of ocular diseases |
-
2012
- 2012-12-07 EP EP12196007.4A patent/EP2740485B1/en not_active Not-in-force
-
2013
- 2013-12-09 CA CA2891201A patent/CA2891201A1/en not_active Abandoned
- 2013-12-09 WO PCT/EP2013/075981 patent/WO2014087022A1/en not_active Ceased
- 2013-12-09 MX MX2015006779A patent/MX2015006779A/es unknown
- 2013-12-09 CN CN201380064175.2A patent/CN105188731B/zh not_active Expired - Fee Related
- 2013-12-09 SG SG10201705592YA patent/SG10201705592YA/en unknown
- 2013-12-09 EA EA201591095A patent/EA201591095A1/ru unknown
- 2013-12-09 KR KR1020157015595A patent/KR20150108351A/ko not_active Withdrawn
- 2013-12-09 BR BR112015013215A patent/BR112015013215A2/pt not_active IP Right Cessation
- 2013-12-09 US US14/650,277 patent/US10098925B2/en not_active Expired - Fee Related
- 2013-12-09 AU AU2013353957A patent/AU2013353957B2/en not_active Ceased
- 2013-12-09 SG SG11201503658XA patent/SG11201503658XA/en unknown
- 2013-12-09 JP JP2015546050A patent/JP6335188B2/ja not_active Expired - Fee Related
-
2015
- 2015-05-26 ZA ZA2015/03747A patent/ZA201503747B/en unknown
- 2015-05-28 IL IL239078A patent/IL239078A0/en unknown
- 2015-06-04 CL CL2015001520A patent/CL2015001520A1/es unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Gao et al. | In situ formation of injectable hydrogels for chronic wound healing | |
| Hassiba et al. | Review of recent research on biomedical applications of electrospun polymer nanofibers for improved wound healing | |
| Wu et al. | Star polymers: Advances in biomedical applications | |
| UA111162C2 (uk) | Ін'єкційна композиція ацетоніду триамцинолону для лікування болю | |
| García et al. | Self-assembled nanomaterials | |
| JP2012025955A5 (https=) | ||
| WO2012054923A3 (en) | Therapeutic nanoparticles with high molecular weight copolymers | |
| RU2008131300A (ru) | Длительное высвобождение нейрегулина для улучшения сердечной функции | |
| JP2014532623A5 (https=) | ||
| JP2011528333A5 (https=) | ||
| EA033537B1 (ru) | Инъекционная композиция с контролируемым высвобождением, содержащая жидкий носитель с высокой вязкостью | |
| US20230313191A1 (en) | Rna comprising secretomes and methods of their use | |
| Mogoşanu et al. | Natural and synthetic polymers for drug delivery and targeting | |
| WO2012012347A3 (en) | Methods of intravenous administration of glyburide and other drugs | |
| FI3858375T3 (fi) | Hyytymishäiriön hoito antamalla rekombinanttia von Willebrand -tekijää | |
| KR101777910B1 (ko) | 만성창상 치료용 조성물, 이의 제조방법 및 이를 이용한 만성창상 치료용 드레싱재 | |
| NZ630040A (en) | Polyinosinic-polycytidylic acid (poly (i:c)) formulations for the treatment of upper respiratory tract infections | |
| FI3659627T3 (fi) | Polyfosfaattifunktionalisoituja epäorgaanisia nanopartikkeleita hemostaattisina koostumuksina ja käyttömenetelmiä | |
| JP2016502558A5 (https=) | ||
| JP2021504448A5 (https=) | ||
| HRP20191144T1 (hr) | Sirnk i njihova primjena u metodama i spojevima za liječenje i/ili prevenciju stanja oka | |
| JP2015514115A5 (https=) | ||
| WO2012049324A3 (en) | New emd formulation comprising pga | |
| Hu et al. | Multifunctional nanocomposite hydrogels: an effective approach to promote diabetic wound healing | |
| JP2014530246A5 (https=) |