AU2013353957B2 - Protein slurp-1 for use in the treatment of ocular diseases - Google Patents

Protein slurp-1 for use in the treatment of ocular diseases Download PDF

Info

Publication number
AU2013353957B2
AU2013353957B2 AU2013353957A AU2013353957A AU2013353957B2 AU 2013353957 B2 AU2013353957 B2 AU 2013353957B2 AU 2013353957 A AU2013353957 A AU 2013353957A AU 2013353957 A AU2013353957 A AU 2013353957A AU 2013353957 B2 AU2013353957 B2 AU 2013353957B2
Authority
AU
Australia
Prior art keywords
cys
protein
thr
ser
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU2013353957A
Other languages
English (en)
Other versions
AU2013353957A1 (en
Inventor
Claire Abadie
Jean-Marc Combette
Catherine Deloche
Sebastien Mouz
Julien Perino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BRIGHTPULSE HOLDING Ltd
Original Assignee
BRIGHTPULSE HOLDING Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BRIGHTPULSE HOLDING Ltd filed Critical BRIGHTPULSE HOLDING Ltd
Publication of AU2013353957A1 publication Critical patent/AU2013353957A1/en
Application granted granted Critical
Publication of AU2013353957B2 publication Critical patent/AU2013353957B2/en
Ceased legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cell Biology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
AU2013353957A 2012-12-07 2013-12-09 Protein slurp-1 for use in the treatment of ocular diseases Ceased AU2013353957B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12196007.4 2012-12-07
EP12196007.4A EP2740485B1 (en) 2012-12-07 2012-12-07 Protein slurp-1 for use in the treatment of ocular diseases
PCT/EP2013/075981 WO2014087022A1 (en) 2012-12-07 2013-12-09 Protein slurp-1 for use in the treatment of ocular diseases

Publications (2)

Publication Number Publication Date
AU2013353957A1 AU2013353957A1 (en) 2015-05-28
AU2013353957B2 true AU2013353957B2 (en) 2018-05-17

Family

ID=47297008

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2013353957A Ceased AU2013353957B2 (en) 2012-12-07 2013-12-09 Protein slurp-1 for use in the treatment of ocular diseases

Country Status (15)

Country Link
US (1) US10098925B2 (https=)
EP (1) EP2740485B1 (https=)
JP (1) JP6335188B2 (https=)
KR (1) KR20150108351A (https=)
CN (1) CN105188731B (https=)
AU (1) AU2013353957B2 (https=)
BR (1) BR112015013215A2 (https=)
CA (1) CA2891201A1 (https=)
CL (1) CL2015001520A1 (https=)
EA (1) EA201591095A1 (https=)
IL (1) IL239078A0 (https=)
MX (1) MX2015006779A (https=)
SG (2) SG10201705592YA (https=)
WO (1) WO2014087022A1 (https=)
ZA (1) ZA201503747B (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2740485B1 (en) * 2012-12-07 2018-10-31 Brightpulse Holding LTD. Protein slurp-1 for use in the treatment of ocular diseases
EP3689327B1 (fr) * 2019-01-24 2025-03-12 Organes Tissus Régénération Réparation Remplacement Composition pharmaceutique dans le traitement de lésions pulmonaires
CN114601915B (zh) * 2022-03-25 2023-04-07 四川大学华西医院 Slurp1蛋白在制备预防或治疗皮肤弹性纤维疾病的药物中的用途

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994014959A1 (en) * 1992-12-22 1994-07-07 Applied Research Systems Ars Holding N.V. New protein from urine named component b
WO2004091646A2 (en) * 2003-04-16 2004-10-28 Applied Research Systems Ars Holding, N.V. Use of slurp-1 for treating diseases related to acetylcholine receptors dysfunction
WO2010138379A2 (en) * 2009-05-29 2010-12-02 Allergan, Inc. Methods of treating chronic neurogenic inflammation using galanin retargeted endopeptidases

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2806143A1 (en) * 2010-07-30 2012-02-02 Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mb H Drug delivery devices and growth factor formulations for accelerated wound healing
EP3848055A1 (en) * 2011-06-03 2021-07-14 Ophidion Inc. Compositions and methods for transport across the blood brain barrier
US9132193B2 (en) * 2012-11-05 2015-09-15 University of Pittsburgh—of the Commonwealth System of Higher Education Use of Slurp1 as an imunomodulatory molecule in the ocular surface
CA2890424C (en) * 2012-11-08 2020-11-17 Yamaguchi University Therapeutic agent for keratoconjunctive disorders
EP2740485B1 (en) * 2012-12-07 2018-10-31 Brightpulse Holding LTD. Protein slurp-1 for use in the treatment of ocular diseases

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994014959A1 (en) * 1992-12-22 1994-07-07 Applied Research Systems Ars Holding N.V. New protein from urine named component b
WO2004091646A2 (en) * 2003-04-16 2004-10-28 Applied Research Systems Ars Holding, N.V. Use of slurp-1 for treating diseases related to acetylcholine receptors dysfunction
WO2010138379A2 (en) * 2009-05-29 2010-12-02 Allergan, Inc. Methods of treating chronic neurogenic inflammation using galanin retargeted endopeptidases

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ALEXANDER I. CHERNYAVSKY ET AL, (2012-01-01), vol. 20, no. 1, doi:10.1111/j.1524-475X.2011.00753.x, ISSN 1067-1927, pages 103 - 113 *
ELDER MARK J ET AL, "Progression of disease in ocular cicatricial pemphigoid", BRITISH JOURNAL OF OPHTHALMOLOGY, (1996), vol. 80, no. 4, ISSN 0007-1161, pages 292 - 296 *
SWAMYNATHAN SUDHA ET AL, "Klf4 Regulates the Expression of Slurp1, Which Functions as an Immunomodulatory Peptide in the Mouse Cornea", IOVS, (2012-11-08), vol. 53, no. 13, pages 8433 - 8446 *

Also Published As

Publication number Publication date
IL239078A0 (en) 2015-07-30
EP2740485A1 (en) 2014-06-11
SG11201503658XA (en) 2015-06-29
CN105188731B (zh) 2019-02-05
SG10201705592YA (en) 2017-08-30
BR112015013215A2 (pt) 2018-02-06
CN105188731A (zh) 2015-12-23
CA2891201A1 (en) 2014-06-12
EP2740485B1 (en) 2018-10-31
ZA201503747B (en) 2016-03-30
AU2013353957A1 (en) 2015-05-28
CL2015001520A1 (es) 2016-05-20
US20150320831A1 (en) 2015-11-12
JP2016502558A (ja) 2016-01-28
EA201591095A1 (ru) 2015-11-30
KR20150108351A (ko) 2015-09-25
WO2014087022A1 (en) 2014-06-12
MX2015006779A (es) 2015-10-29
US10098925B2 (en) 2018-10-16
JP6335188B2 (ja) 2018-05-30

Similar Documents

Publication Publication Date Title
RU2705211C2 (ru) Композиция и способ лечения кожных рубцов
KR102412659B1 (ko) Rgd 모티프 함유 펩티드 또는 이의 단편을 포함하는 화상 및 녹내장 치료, 피부 주름 개선 및 발모 촉진용 조성물
EP2508196B1 (en) Use of PEDF-derived polypeptides for promoting stem cells proliferation and wound healing
JP6416240B2 (ja) 種々の皮膚症状の処置に有用なヒトc−x−cケモカイン由来テトラペプチド
US5155038A (en) Use of thrombospondin to promote wound healing
CN105120884B (zh) 用于促进伤口愈合的短生物活性肽
CN107252478A (zh) 弹性纤维的体内合成
TR201809034T4 (tr) Biyo-rejeneratif, restoratif ve ötrofik aktiviteye sahip bileşim.
KR20080031405A (ko) 상피 재생의 촉진
AU2013353957B2 (en) Protein slurp-1 for use in the treatment of ocular diseases
CN111420023B (zh) 含i型胶原和透明质酸的复合物及制备和用途
Leibowitz et al. Effect of topically administered epidermal growth factor on corneal wound strength
BRPI0720874B1 (pt) composições compreendendo peptídeos bioativos curtos para modulação celular e imunológica
CN115991758B (zh) 一种促进糖尿病创面愈合的珍珠粉多肽及其应用
TW201204384A (en) Lactoferrin sequences, compositions and methods of wound treatment
ES2475243T3 (es) Uso del pentap�ptido PHSRN en formulaciones oft�lmicas
CN111346217B (zh) 多肽tdl23的新用途
EP3893920B1 (en) Composition for the treatment of skin lesions
WO2020037714A1 (zh) Trail突变体在制备治疗痤疮药物中的应用及一种制剂
Mao et al. Bioactive thermoresponsive fibronectin–Pluronic F127 hydrogel for sustained ocular delivery with corneal regeneration and anti-inflammatory effects
Elkhawaga et al. Assessment of Corneal Epithelial Healing Rate after Pterygium Excision When Using 2% Hyaluronic Acid.
US20240207373A1 (en) Cyclic peptides from the c-terminus of acetylcholinesterase for treatment of skin disorders and for cosmetical use
JP2025542389A (ja) 創傷治癒および損傷神経の修復のための組成物および方法
HK40091784A (zh) 治疗伤口的组合物和方法
CN116685344A (zh) 治疗伤口的组合物和方法

Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired