JP2016501525A5 - - Google Patents
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- Publication number
- JP2016501525A5 JP2016501525A5 JP2015545945A JP2015545945A JP2016501525A5 JP 2016501525 A5 JP2016501525 A5 JP 2016501525A5 JP 2015545945 A JP2015545945 A JP 2015545945A JP 2015545945 A JP2015545945 A JP 2015545945A JP 2016501525 A5 JP2016501525 A5 JP 2016501525A5
- Authority
- JP
- Japan
- Prior art keywords
- compartment
- partition
- fixed bed
- retainer
- cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000005192 partition Methods 0.000 claims 15
- 239000012530 fluid Substances 0.000 claims 4
- 239000000463 material Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261735841P | 2012-12-11 | 2012-12-11 | |
| US61/735,841 | 2012-12-11 | ||
| PCT/US2013/074298 WO2014093439A1 (en) | 2012-12-11 | 2013-12-11 | System and method for detachment of cells in fixed bed reactors |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016501525A JP2016501525A (ja) | 2016-01-21 |
| JP2016501525A5 true JP2016501525A5 (https=) | 2016-11-10 |
Family
ID=50934912
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545945A Pending JP2016501525A (ja) | 2012-12-11 | 2013-12-11 | 固定床リアクタにおける細胞の分離のためのシステムおよび方法 |
| JP2015545946A Pending JP2016504024A (ja) | 2012-12-11 | 2013-12-11 | 細胞培養のための受容体 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545946A Pending JP2016504024A (ja) | 2012-12-11 | 2013-12-11 | 細胞培養のための受容体 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US10781417B2 (https=) |
| EP (2) | EP2931870A4 (https=) |
| JP (2) | JP2016501525A (https=) |
| CN (3) | CN104903435A (https=) |
| SG (2) | SG11201504219QA (https=) |
| WO (2) | WO2014093444A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8506797B2 (en) * | 2011-04-10 | 2013-08-13 | Therapeutic Proteins International, LLC | Downstream bioprocessing device |
| CN112662611B (zh) * | 2014-01-23 | 2024-10-29 | 日产化学工业株式会社 | 培养基组合物 |
| JP6351113B2 (ja) * | 2015-01-29 | 2018-07-04 | 藤森工業株式会社 | 振とう型培養装置及びこれを用いた培養方法 |
| US10344257B2 (en) | 2015-07-24 | 2019-07-09 | Bioreactor Sciences Llc | Horizontally rocked bioreactor system |
| TWI672375B (zh) * | 2015-12-09 | 2019-09-21 | 財團法人工業技術研究院 | 細胞培養載體模組、生物反應器及細胞回收方法 |
| WO2017112455A2 (en) | 2015-12-22 | 2017-06-29 | Corning Incorporated | Cell separation device and method for using same |
| CA3021572A1 (en) | 2016-04-20 | 2017-10-26 | Centro De Investigaciones Energeticas, Medioambientales Y Tecnologicas | Compositions and methods for enhanced gene expression of pklr |
| WO2018044699A1 (en) | 2016-08-27 | 2018-03-08 | 3D Biotek, Llc | Bioreactor |
| BE1024733B1 (fr) | 2016-11-09 | 2018-06-14 | Univercells Sa | Matrice de croissance cellulaire |
| JP6699837B2 (ja) * | 2016-12-27 | 2020-05-27 | 株式会社フルステム | 3次元多孔性足場からの培養細胞回収方法 |
| US20200115666A1 (en) | 2017-03-28 | 2020-04-16 | Corning Incorporated | Aseptic bioprocess package |
| EP3697452A4 (en) | 2017-10-16 | 2021-11-24 | Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, O.A., M.P. | LENTIVIRAL VECTORS FOR ADMINISTRATION OF PKLR TO TREAT PYRUVATE KINASE DEFECTS |
| KR102714703B1 (ko) | 2017-12-20 | 2024-10-07 | 유니버셀스 테크놀로지스 에스.에이. | 생물반응기 및 관련 방법 |
| BR112020020841A2 (pt) | 2018-04-11 | 2021-01-19 | Fundacion Para La Investigacion Biomedica Del Hospital Infantil Universitario Nino Jesus | Composições e métodos para transplante de célulastronco |
| IT201800004911A1 (it) * | 2018-04-27 | 2019-10-27 | Apparecchiatura per la fermentazione dinamica in stato solido | |
| JP6628448B2 (ja) * | 2018-05-29 | 2020-01-08 | 藤森工業株式会社 | 振とう型培養装置及びこれを用いた培養方法 |
| CN108913600B (zh) * | 2018-08-16 | 2023-06-27 | 杭州德适生物科技有限公司 | 一种显微授精操作皿 |
| US11692161B2 (en) | 2019-02-05 | 2023-07-04 | Corning Incorporated | Packed-bed bioreactor systems and methods of using the same |
| WO2021055934A1 (en) * | 2019-09-20 | 2021-03-25 | Pancopia, Inc | Animal husbandry nutrient and odor management system |
| US11118151B2 (en) | 2019-11-05 | 2021-09-14 | Corning Incorporated | Fixed bed bioreactor and methods of using the same |
| CN114761534B (zh) * | 2019-11-27 | 2025-09-16 | 康宁股份有限公司 | 固定床细胞培养和收获系统及其使用方法 |
| US12422294B2 (en) | 2019-12-31 | 2025-09-23 | Cytiva Us Llc | Biocontainer assembly for bioprocessing system |
| US20220186168A1 (en) * | 2020-12-11 | 2022-06-16 | Cell Spinpod LLC | Rotating suspension culture devices that allow direct microscopy, in situ assays, and automation |
| US20240279598A1 (en) * | 2021-06-03 | 2024-08-22 | Univercells Technologies Sa | Bioreactor system with enhanced cell harvesting capabilities and related methods |
| CN114456938A (zh) * | 2022-03-02 | 2022-05-10 | 蓝莲(杭州)生物科技有限公司 | 滚动式细胞培养仪 |
| WO2023249816A1 (en) * | 2022-06-22 | 2023-12-28 | Corning Incorporated | Fixed bed cell culture reactor vessel for substrate alignment and sampling |
| CN115786120A (zh) * | 2022-11-01 | 2023-03-14 | 上海东富龙医疗装备有限公司 | 用于贴壁细胞培养的一次性固定床 |
| EP4619499A2 (en) * | 2022-11-18 | 2025-09-24 | Univercells Technologies SA | Systems and methods for recovering target biomolecules from fixed bed bioreactors |
| WO2025049667A1 (en) * | 2023-08-31 | 2025-03-06 | Corning Incorporated | Perfusion bioreactors and systems for large scale cell culture |
| TWM664031U (zh) * | 2024-01-22 | 2024-12-01 | 覺之能量研究有限公司 | 細胞培養輔助器 |
| WO2026012929A1 (en) * | 2024-07-07 | 2026-01-15 | Univercells Technologies Sa | Apparatus for cell culturing and related methods |
| CN119776116B (zh) * | 2025-03-10 | 2025-05-09 | 湖南中瑞互信医疗科技有限公司 | 一种恒温孵育摇床装置 |
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| US4253947A (en) * | 1979-02-12 | 1981-03-03 | Kansas State University Research Foundation | Method for wastewater treatment in fluidized bed biological reactors |
| US4322296A (en) * | 1980-08-12 | 1982-03-30 | Kansas State Univ. Research Foundation | Method for wastewater treatment in fluidized bed biological reactors |
| US5266476A (en) | 1985-06-18 | 1993-11-30 | Yeda Research & Development Co., Ltd. | Fibrous matrix for in vitro cell cultivation |
| US4720462A (en) | 1985-11-05 | 1988-01-19 | Robert Rosenson | Culture system for the culture of solid tissue masses and method of using the same |
| JPH02109973A (ja) * | 1988-10-19 | 1990-04-23 | Shimadzu Corp | 細胞培養装置 |
| JPH02177882A (ja) * | 1988-12-29 | 1990-07-10 | Shimadzu Corp | 細胞培養装置用レベルセンサ |
| JPH0728722B2 (ja) * | 1990-06-29 | 1995-04-05 | 富士写真フイルム株式会社 | バイオリアクター装置 |
| WO1992007615A1 (en) * | 1990-10-29 | 1992-05-14 | Regents Of The University Of Minnesota | A bioartificial liver |
| BE1004610A5 (fr) | 1990-11-29 | 1992-12-22 | Spielmann Richard | Bioreacteur rotatif a grande surface pour culture de cellules adherentes ou en suspension. |
| FR2690926B1 (fr) | 1992-05-06 | 1995-08-04 | Lvmh Rech | Dispositif du type reacteur a volume variable et procede de culture cellulaire. |
| IL108321A (en) | 1994-01-12 | 1998-10-30 | Yeda Res & Dev | Bioreactor and system for improved productivity of photosynthetic algae |
| US5958761A (en) | 1994-01-12 | 1999-09-28 | Yeda Research And Developement Co. Ltd. | Bioreactor and system for improved productivity of photosynthetic algae |
| US5527705A (en) | 1994-09-12 | 1996-06-18 | Becton, Dickinson And Company | Roller bottle for trans-membrane co-culture of cells and method for its use |
| JP3639007B2 (ja) | 1995-08-22 | 2005-04-13 | 京都水研株式会社 | 攪拌槽型のバイオリアクタ |
| GB9803362D0 (en) * | 1998-02-17 | 1998-04-15 | Cellon Sa | A cell culture vessel |
| JP2000125848A (ja) * | 1998-10-19 | 2000-05-09 | Agriculture Forestry & Fisheries Technical Information Society | 細胞培養用具及び前記細胞培養用具を用いる簡易細胞培養方法 |
| WO2001055293A2 (en) * | 2000-01-25 | 2001-08-02 | The Victoria University Of Manchester | Delayed release of fluids |
| US6720178B1 (en) * | 2000-06-29 | 2004-04-13 | University Of Louisville Research Foundation, Inc. | Self-feeding roller bottle |
| US20020155594A1 (en) | 2001-03-27 | 2002-10-24 | Hsieh Helen V. | Method and apparatus for culturing cells |
| KR20020088848A (ko) | 2001-05-21 | 2002-11-29 | (주)코아바이오텍 | 세포배양관 및 이를 이용한 대량 세포배양기 |
| WO2003008931A2 (en) * | 2001-07-17 | 2003-01-30 | Georgi Hvichia | Microstructure for particle and cell separation, identification, sorting, and manipulation |
| TWI242600B (en) * | 2001-11-09 | 2005-11-01 | Ind Tech Res Inst | Collection, culture device and method for drawing out cell suspension from cell supply source |
| JP2004041093A (ja) * | 2002-07-12 | 2004-02-12 | Mitsubishi Heavy Ind Ltd | 細胞培養装置および細胞培養方法 |
| CA2493477A1 (en) * | 2002-07-31 | 2004-02-05 | Japan Science And Technology Agency | Automatic culture apparatus for cell or tissue with biological origin |
| JP4242618B2 (ja) * | 2002-09-03 | 2009-03-25 | オリンパス株式会社 | 培養装置 |
| JP2004089136A (ja) * | 2002-09-03 | 2004-03-25 | Olympus Corp | 培養容器 |
| CN1300297C (zh) * | 2002-09-20 | 2007-02-14 | 华东理工大学 | 一种用于动物细胞扩大接种的消化反应器 |
| US7390653B2 (en) | 2002-12-04 | 2008-06-24 | Synthecon, Inc. | Culture chamber for biologicals |
| CA2514196A1 (en) | 2003-02-13 | 2004-08-26 | Ilc Dover, Inc. | Flexible disposable vessel |
| DE10322054B4 (de) * | 2003-05-15 | 2015-06-18 | Sartorius Stedim Biotech Gmbh | Vorrichtung und Verfahren zur Kultivierung von Zellen |
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| EP1739164B1 (en) | 2004-04-13 | 2016-08-10 | Toyo Seikan Group Holdings, Ltd. | Double incubator and incubating method |
| DE102004062828B4 (de) | 2004-12-27 | 2007-01-11 | Fresenius Medical Care Deutschland Gmbh | Reaktor mit einer rotierbar angeordneten Reaktoreinheit |
| CN1740314A (zh) * | 2005-07-21 | 2006-03-01 | 高春平 | 持续灌注式自动细胞培养系统 |
| BE1016793A4 (fr) * | 2005-10-04 | 2007-06-05 | Artelis | Procede de culture de cellules et dispositif permettant sa mise en oeuvre. |
| US7856704B2 (en) * | 2005-10-14 | 2010-12-28 | Gm Global Technology Operations, Inc. | Monitoring system for clinching process |
| JP2007222064A (ja) * | 2006-02-23 | 2007-09-06 | Scimedia Ltd | ホローファイバー型培養装置 |
| DE102006044795A1 (de) * | 2006-09-13 | 2008-03-27 | Schweigert, Florian, Prof. Dr.med.vet. | Bestimmung von Inhaltsstoffen aus biologischen Materialien |
| WO2008136371A1 (ja) | 2007-04-27 | 2008-11-13 | Toyo Seikan Kaisha, Ltd. | 細胞培養装置、細胞培養システム及び細胞培養方法 |
| WO2009139703A1 (en) * | 2008-05-15 | 2009-11-19 | Ge Healthcare Bio-Sciences Ab | Method for cell expansion |
| DE102008039812A1 (de) | 2008-08-25 | 2010-03-04 | Yvonne Ibold | Vorrichtung und Verfahren zur Kultivierung von adhärenten Zellen |
| WO2010040060A2 (en) * | 2008-10-02 | 2010-04-08 | Gay Roger J | Bioreactor with rods arrayed for culturing anchorage-dependent cells |
| FR2943560B1 (fr) * | 2009-03-24 | 2011-05-27 | Jean Pascal Zambaux | Bioreacteur jetable et systeme d'agitation a usage unique |
| CN102108333B (zh) * | 2009-12-29 | 2014-08-13 | 上海日泰医药设备工程有限公司 | 一种流化床生物反应器 |
| JP2013533171A (ja) * | 2010-04-19 | 2013-08-22 | エイティーエムアイ ビーブイビーエイ | 流体処理および貯蔵容器用のドレンコネクタ |
| JP5947790B2 (ja) * | 2010-05-25 | 2016-07-06 | クック・バイオテック・インコーポレイテッドCook Biotech Incorporated | 医療用移植片の細胞播種に有用な方法、基質、およびシステム |
| JP2014515605A (ja) * | 2011-03-28 | 2014-07-03 | コーニング インコーポレイテッド | 耐キンク性コネクタを備えた容器蓋 |
| SG10201601537QA (en) * | 2011-04-15 | 2016-04-28 | Pluristem Ltd | Methods and systems for harvesting cells |
-
2013
- 2013-12-11 SG SG11201504219QA patent/SG11201504219QA/en unknown
- 2013-12-11 CN CN201380064957.6A patent/CN104903435A/zh active Pending
- 2013-12-11 EP EP13862027.3A patent/EP2931870A4/en active Pending
- 2013-12-11 EP EP13862977.9A patent/EP2931871B1/en active Active
- 2013-12-11 US US14/648,571 patent/US10781417B2/en active Active
- 2013-12-11 JP JP2015545945A patent/JP2016501525A/ja active Pending
- 2013-12-11 WO PCT/US2013/074307 patent/WO2014093444A1/en not_active Ceased
- 2013-12-11 CN CN201380064887.4A patent/CN105229139B/zh active Active
- 2013-12-11 JP JP2015545946A patent/JP2016504024A/ja active Pending
- 2013-12-11 WO PCT/US2013/074298 patent/WO2014093439A1/en not_active Ceased
- 2013-12-11 CN CN202111185751.1A patent/CN114214192A/zh active Pending
- 2013-12-11 US US14/648,590 patent/US10280391B2/en active Active
- 2013-12-11 SG SG11201504217UA patent/SG11201504217UA/en unknown
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