JP2016501230A5 - - Google Patents
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- Publication number
- JP2016501230A5 JP2016501230A5 JP2015545438A JP2015545438A JP2016501230A5 JP 2016501230 A5 JP2016501230 A5 JP 2016501230A5 JP 2015545438 A JP2015545438 A JP 2015545438A JP 2015545438 A JP2015545438 A JP 2015545438A JP 2016501230 A5 JP2016501230 A5 JP 2016501230A5
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- seq
- acid sequence
- antibody
- variable region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261731294P | 2012-11-29 | 2012-11-29 | |
| US61/731,294 | 2012-11-29 | ||
| US201361786472P | 2013-03-15 | 2013-03-15 | |
| US61/786,472 | 2013-03-15 | ||
| PCT/US2013/072243 WO2014085596A1 (en) | 2012-11-29 | 2013-11-27 | MONOCLONAL ANTIBODIES AGAISNT ACTIVATED PROTEIN C (aPC) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016501230A JP2016501230A (ja) | 2016-01-18 |
| JP2016501230A5 true JP2016501230A5 (https=) | 2017-01-12 |
Family
ID=50828462
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015545438A Pending JP2016501230A (ja) | 2012-11-29 | 2013-11-27 | 活性化プロテインＣ（ａＰＣ）に対するモノクローナル抗体 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20150307625A1 (https=) |
| EP (1) | EP2925351A4 (https=) |
| JP (1) | JP2016501230A (https=) |
| KR (1) | KR20150088869A (https=) |
| CN (1) | CN104812402A (https=) |
| AR (1) | AR093671A1 (https=) |
| AU (1) | AU2013352159A1 (https=) |
| BR (1) | BR112015012414A2 (https=) |
| CA (1) | CA2892750A1 (https=) |
| HK (1) | HK1212896A1 (https=) |
| IL (1) | IL238658A0 (https=) |
| MX (1) | MX2015006424A (https=) |
| RU (1) | RU2015125349A (https=) |
| SG (1) | SG11201503719WA (https=) |
| TW (1) | TW201429992A (https=) |
| UY (1) | UY35154A (https=) |
| WO (1) | WO2014085596A1 (https=) |
| ZA (1) | ZA201504659B (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11077187B2 (en) * | 2015-11-17 | 2021-08-03 | Oklahoma Medical Research Foundation | Epitope of optimized humanized monoclonal antibodies against activated protein C and uses thereof |
| EP3831843A1 (en) | 2019-12-08 | 2021-06-09 | Royal College Of Surgeons In Ireland | A hemostatic agent and uses thereof |
| CN115611986B (zh) * | 2021-07-13 | 2025-08-12 | 上海莱士血液制品股份有限公司 | 针对人活化蛋白c的单克隆抗体及其制备和应用 |
| CN116496394B (zh) * | 2022-01-26 | 2024-07-23 | 东莞市朋志生物科技有限公司 | 抗s100蛋白的抗体、检测s100蛋白的试剂和试剂盒 |
| CA3245346A1 (en) * | 2022-03-04 | 2023-09-07 | Coagulant Therapeutics Corporation | Camelid antibodies directed against activated protein C and their uses |
| CN118370814A (zh) * | 2023-01-20 | 2024-07-23 | 上海莱士血液制品股份有限公司 | 一种抗aPC单克隆抗体的制剂及其应用 |
| US20250002588A1 (en) | 2023-04-07 | 2025-01-02 | Diagonal Therapeutics Inc. | Bispecific agonistic antibodies to activin a receptor like type 1 (alk1) |
| WO2025149667A1 (en) | 2024-01-12 | 2025-07-17 | Pheon Therapeutics Ltd | Antibody drug conjugates and uses thereof |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993009804A1 (en) * | 1991-11-18 | 1993-05-27 | The Scripps Research Institute | Serine protease derived-polypeptides and anti-peptide antibodies, systems and therapeutic methods for inhibiting coagulation |
| PT1754718E (pt) * | 1996-04-24 | 2011-07-13 | Univ Michigan | Factor viii resistente à inactivação |
| ATE464374T1 (de) * | 2000-10-02 | 2010-04-15 | Oklahoma Med Res Found | Assay zum schnellen nachweis vom humanen aktivierten protein c und hochspezifischer monoklonaler antikörper dagegen |
| US20030226155A1 (en) * | 2001-08-30 | 2003-12-04 | Biorexis Pharmaceutical Corporation | Modified transferrin-antibody fusion proteins |
| US20030203355A1 (en) * | 2002-04-24 | 2003-10-30 | Los Alamos National Laboratory | Fluorobodies: binding ligands with intrinsic fluorescence |
| GB0309126D0 (en) * | 2003-04-17 | 2003-05-28 | Neutec Pharma Plc | Clostridium difficile focussed antibodies |
| CA2575791A1 (en) * | 2004-08-03 | 2006-02-16 | Dyax Corp. | Hk1-binding proteins |
| CA2591665C (en) * | 2004-12-20 | 2015-05-05 | Crucell Holland B.V. | Binding molecules capable of neutralizing west nile virus and uses thereof |
| ES2385054T3 (es) * | 2005-12-13 | 2012-07-17 | Medimmune Limited | Proteínas de unión específicas para factores de crecimiento de tipo insulina y usos de las mismas |
| US8039597B2 (en) * | 2007-09-07 | 2011-10-18 | Agensys, Inc. | Antibodies and related molecules that bind to 24P4C12 proteins |
| TWI489993B (zh) * | 2007-10-12 | 2015-07-01 | Novartis Ag | 骨硬化素（ｓｃｌｅｒｏｓｔｉｎ）抗體組合物及使用方法 |
| JP2011500843A (ja) * | 2007-10-26 | 2011-01-06 | オクラホマ・メディカル・リサーチ・ファウンデーション | 活性化プロテインｃおよび不活性化プロテインｃに対するモノクロナール抗体 |
| GB0903151D0 (en) * | 2009-02-25 | 2009-04-08 | Bioinvent Int Ab | Antibody uses and methods |
| US8926976B2 (en) * | 2009-09-25 | 2015-01-06 | Xoma Technology Ltd. | Modulators |
| GB201011771D0 (en) * | 2010-07-13 | 2010-08-25 | Bioinvent Int Ab | Biological material and particular uses thereof |
| GB201013989D0 (en) * | 2010-08-20 | 2010-10-06 | Univ Southampton | Biological materials and methods of using the same |
| JP2014500874A (ja) * | 2010-11-16 | 2014-01-16 | メディミューン，エルエルシー | 抗ｉｇｆ抗体を用いた治療レジメン |
| US8440797B2 (en) * | 2010-12-06 | 2013-05-14 | Dainippon Sumitomo Pharma Co., Ltd. | Human monoclonal antibody |
| GB201020995D0 (en) * | 2010-12-10 | 2011-01-26 | Bioinvent Int Ab | Biological materials and uses thereof |
-
2013
- 2013-11-27 CN CN201380062159.XA patent/CN104812402A/zh active Pending
- 2013-11-27 AU AU2013352159A patent/AU2013352159A1/en not_active Abandoned
- 2013-11-27 WO PCT/US2013/072243 patent/WO2014085596A1/en not_active Ceased
- 2013-11-27 CA CA2892750A patent/CA2892750A1/en not_active Abandoned
- 2013-11-27 BR BR112015012414A patent/BR112015012414A2/pt not_active IP Right Cessation
- 2013-11-27 SG SG11201503719WA patent/SG11201503719WA/en unknown
- 2013-11-27 KR KR1020157017008A patent/KR20150088869A/ko not_active Withdrawn
- 2013-11-27 HK HK16100878.9A patent/HK1212896A1/zh unknown
- 2013-11-27 US US14/443,710 patent/US20150307625A1/en not_active Abandoned
- 2013-11-27 MX MX2015006424A patent/MX2015006424A/es unknown
- 2013-11-27 RU RU2015125349A patent/RU2015125349A/ru not_active Application Discontinuation
- 2013-11-27 EP EP13857869.5A patent/EP2925351A4/en not_active Withdrawn
- 2013-11-27 JP JP2015545438A patent/JP2016501230A/ja active Pending
- 2013-11-28 UY UY0001035154A patent/UY35154A/es not_active Application Discontinuation
- 2013-11-28 TW TW102143366A patent/TW201429992A/zh unknown
- 2013-11-29 AR ARP130104417A patent/AR093671A1/es unknown
-
2015
- 2015-05-06 IL IL238658A patent/IL238658A0/en unknown
- 2015-06-26 ZA ZA2015/04659A patent/ZA201504659B/en unknown
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