JP2012519712A5 - - Google Patents

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Publication number
JP2012519712A5
JP2012519712A5 JP2011553163A JP2011553163A JP2012519712A5 JP 2012519712 A5 JP2012519712 A5 JP 2012519712A5 JP 2011553163 A JP2011553163 A JP 2011553163A JP 2011553163 A JP2011553163 A JP 2011553163A JP 2012519712 A5 JP2012519712 A5 JP 2012519712A5
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JP
Japan
Prior art keywords
formulation
seq
antibody
sugar chain
variable region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2011553163A
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English (en)
Japanese (ja)
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JP2012519712A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2010/026492 external-priority patent/WO2010102276A2/en
Publication of JP2012519712A publication Critical patent/JP2012519712A/ja
Publication of JP2012519712A5 publication Critical patent/JP2012519712A5/ja
Withdrawn legal-status Critical Current

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JP2011553163A 2009-03-06 2010-03-08 ヒト化抗cd19抗体製剤 Withdrawn JP2012519712A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15815309P 2009-03-06 2009-03-06
US61/158,153 2009-03-06
PCT/US2010/026492 WO2010102276A2 (en) 2009-03-06 2010-03-08 Humanized anti-cd19 antibody formulations

Publications (2)

Publication Number Publication Date
JP2012519712A JP2012519712A (ja) 2012-08-30
JP2012519712A5 true JP2012519712A5 (https=) 2013-05-02

Family

ID=42710248

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011553163A Withdrawn JP2012519712A (ja) 2009-03-06 2010-03-08 ヒト化抗cd19抗体製剤

Country Status (12)

Country Link
US (1) US20120148576A1 (https=)
EP (1) EP2403532A4 (https=)
JP (1) JP2012519712A (https=)
KR (1) KR20110125664A (https=)
CN (1) CN102413839A (https=)
AU (1) AU2010221099A1 (https=)
BR (1) BRPI1013237A2 (https=)
CA (1) CA2754266A1 (https=)
MX (1) MX2011009312A (https=)
RU (1) RU2011140486A (https=)
WO (1) WO2010102276A2 (https=)
ZA (1) ZA201106480B (https=)

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AR076284A1 (es) 2009-04-29 2011-06-01 Bayer Schering Pharma Ag Inmunoconjugados de antimesotelina y usos de los mismos
EP4492053A3 (en) * 2010-05-25 2025-03-19 F. Hoffmann-La Roche AG Methods of purifying polypeptides
WO2013055874A2 (en) 2011-10-14 2013-04-18 Genentech, Inc. Uses for and article of manufacture including her2 dimerization inhibitor pertuzumab
US20130195851A1 (en) * 2011-12-23 2013-08-01 Genentech, Inc. Articles of manufacture and methods for co-administration of antibodies
CN104640560A (zh) * 2012-03-12 2015-05-20 米迪缪尼有限公司 用抗-cd19抗体治疗多发性硬化症
JP2015520625A (ja) * 2012-04-23 2015-07-23 ゾゲニクス インコーポレーティッド 薬物送達カプセルのためのピストン施栓
US20150290244A1 (en) * 2012-07-13 2015-10-15 The Trustees Of The University Of Pennsylvania Use of cart19 to deplete normal b cells to induce tolerance
AU2013201465B2 (en) * 2012-10-24 2016-03-03 Rayner Intraocular Lenses Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
UA117466C2 (uk) 2012-12-13 2018-08-10 Мерк Шарп Енд Доме Корп. СТАБІЛЬНИЙ СКЛАД У ВИГЛЯДІ РОЗЧИНУ АНТИТІЛА ДО IL-23p19
CN110538322A (zh) 2013-03-13 2019-12-06 豪夫迈·罗氏有限公司 抗体配制剂
CN106132434A (zh) * 2014-04-07 2016-11-16 西雅图基因公司 抗‑cd19抗体和抗体‑药物偶联物的稳定制剂
CA2950392A1 (en) * 2014-05-28 2015-12-03 Nono Inc. Lyophilized formulation of tat-nr2b9c with acetylation scavenger
JP7072384B2 (ja) 2014-09-15 2022-05-20 ジェネンテック, インコーポレイテッド 抗体製剤
TWI809304B (zh) 2014-12-01 2023-07-21 奥默羅斯公司 用於抑制術後眼睛炎性病況的抗炎和散瞳前房溶液
US11091543B2 (en) 2015-05-07 2021-08-17 Swedish Orphan Biovitrum Ag Methods, compositions and dosing regimens for treating or preventing interferon-gamma related indications
CN121588213A (zh) 2015-05-07 2026-03-03 瑞典孤儿比奥维特鲁姆股份公司 用于诊断和治疗cxcl9和其它生物标志物水平升高的患者的病症
AR104847A1 (es) * 2015-06-17 2017-08-16 Lilly Co Eli Formulación de anticuerpo anti-cgrp
US10493139B2 (en) 2015-07-24 2019-12-03 Innovative Cellular Therapeutics CO., LTD. Humanized anti-CD19 antibody and use thereof with chimeric antigen receptor
WO2017015783A1 (en) * 2015-07-24 2017-02-02 Shanghai Sidansai Biotechnology Co., Ltd Humanized anti-cd19 antibody and use thereof
SI3475303T1 (sl) * 2016-06-27 2021-12-31 Morphosys Ag Formulacija protitelesa proti CD19
EP3330289A1 (en) * 2016-12-02 2018-06-06 Friedrich-Alexander-Universität Erlangen-Nürnberg A cd33-, cd16- and cd123-specific single chain triplebody
US11077189B2 (en) 2017-03-02 2021-08-03 Genentech Inc. Adjuvant treatment of HER2-positive breast cancer
JOP20190260A1 (ar) * 2017-05-02 2019-10-31 Merck Sharp & Dohme صيغ ثابتة لأجسام مضادة لمستقبل الموت المبرمج 1 (pd-1) وطرق استخدامها
AU2018263868A1 (en) 2017-05-02 2019-12-12 Merck Sharp & Dohme Llc Formulations of anti-LAG3 antibodies and co-formulations of anti-LAG3 antibodies and anti-PD-1 antibodies
WO2019011918A1 (en) 2017-07-10 2019-01-17 International - Drug - Development - Biotech TREATMENT OF LYMPHOCYTE B MALIGNANCIES USING AFUCOSYLATED PRO-APOPTOTIC ANTI-CD19 ANTIBODIES IN COMBINATION WITH ANTI-CD20 ANTIBODIES OR CHEMOTHERAPEUTIC AGENTS
KR102136063B1 (ko) * 2017-12-06 2020-07-22 앱클론(주) 악성 b 세포를 특이적으로 인지하는 항체 또는 그의 항원 결합 단편, 이를 포함하는 키메라 항체 수용체 및 이의 용도
CN120842406A (zh) 2018-10-31 2025-10-28 默沙东有限责任公司 抗人pd-1抗体晶体及其使用方法
CN113316458B (zh) 2018-11-07 2024-08-02 默沙东有限责任公司 抗lag3抗体和抗pd-1抗体的共制剂
KR102735988B1 (ko) 2019-02-18 2024-12-03 일라이 릴리 앤드 캄파니 치료 항체 제제
MX2021012870A (es) * 2019-04-24 2022-01-18 Viela Bio Inc Uso de un anticuerpo anti cúmulo de diferenciación 19 (cd19) para tratar enfermedades autoinmunitarias.
US12544437B2 (en) 2019-10-04 2026-02-10 Ultragenyx Pharmaceutical Inc. Methods for improved therapeutic use of recombinant AAV
KR20220092578A (ko) * 2019-11-05 2022-07-01 브리스톨-마이어스 스큅 컴퍼니 M-단백질 검정 및 이의 용도
WO2022026914A1 (en) * 2020-07-31 2022-02-03 Alamab Therapeutics, Inc. Anti-connexin antibody formulations
JP2024505128A (ja) * 2020-12-30 2024-02-05 アイ-エムエービー バイオファーマ カンパニー リミテッド 抗cd73抗体の製剤
WO2022223028A1 (zh) * 2021-04-23 2022-10-27 上海君实生物医药科技股份有限公司 抗BLyS抗体、其药物组合物及其用途
CN113208810B (zh) * 2021-05-18 2022-04-12 南方医科大学深圳医院 一种用于smile术透镜染色低温分离液的超声波给药装置

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US6171586B1 (en) * 1997-06-13 2001-01-09 Genentech, Inc. Antibody formulation
EP2216342B1 (en) * 2003-07-31 2015-04-22 Immunomedics, Inc. Anti-CD19 antibodies
KR101456728B1 (ko) * 2006-09-08 2014-10-31 메디뮨 엘엘씨 인간화 항-cd19 항체, 및 이것의 종양학, 이식 및 자가면역 질환의 치료에서의 용도

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