JP2016501222A5 - - Google Patents

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Publication number
JP2016501222A5
JP2016501222A5 JP2015545170A JP2015545170A JP2016501222A5 JP 2016501222 A5 JP2016501222 A5 JP 2016501222A5 JP 2015545170 A JP2015545170 A JP 2015545170A JP 2015545170 A JP2015545170 A JP 2015545170A JP 2016501222 A5 JP2016501222 A5 JP 2016501222A5
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JP
Japan
Prior art keywords
methyl
pharmaceutical combination
pharmaceutically acceptable
inhibitor compound
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015545170A
Other languages
English (en)
Japanese (ja)
Other versions
JP6437444B2 (ja
JP2016501222A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/071852 external-priority patent/WO2014085381A1/en
Publication of JP2016501222A publication Critical patent/JP2016501222A/ja
Publication of JP2016501222A5 publication Critical patent/JP2016501222A5/ja
Application granted granted Critical
Publication of JP6437444B2 publication Critical patent/JP6437444B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2015545170A 2012-11-29 2013-11-26 医薬的組合せ Active JP6437444B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261731174P 2012-11-29 2012-11-29
US61/731,174 2012-11-29
US201261731555P 2012-11-30 2012-11-30
US61/731,555 2012-11-30
US201361755520P 2013-01-23 2013-01-23
US61/755,520 2013-01-23
PCT/US2013/071852 WO2014085381A1 (en) 2012-11-29 2013-11-26 Pharmaceutical combinations

Publications (3)

Publication Number Publication Date
JP2016501222A JP2016501222A (ja) 2016-01-18
JP2016501222A5 true JP2016501222A5 (enExample) 2017-01-12
JP6437444B2 JP6437444B2 (ja) 2018-12-12

Family

ID=49753513

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015545170A Active JP6437444B2 (ja) 2012-11-29 2013-11-26 医薬的組合せ

Country Status (16)

Country Link
US (1) US9446043B2 (enExample)
EP (1) EP2925366B1 (enExample)
JP (1) JP6437444B2 (enExample)
CN (1) CN104812415A (enExample)
AU (1) AU2013352379B2 (enExample)
BR (1) BR112015012497B1 (enExample)
CA (1) CA2892578C (enExample)
DK (1) DK2925366T3 (enExample)
ES (1) ES2669248T3 (enExample)
HU (1) HUE037618T2 (enExample)
NZ (1) NZ708802A (enExample)
PL (1) PL2925366T3 (enExample)
RU (1) RU2674995C2 (enExample)
TR (1) TR201806682T4 (enExample)
UA (1) UA115250C2 (enExample)
WO (1) WO2014085381A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201904851D0 (en) 2019-04-05 2019-05-22 Katholieke Univ Leven Melanoma treatment
US11086278B2 (en) 2019-08-29 2021-08-10 Inventus Holdings, Llc Adaptive system monitoring using incremental regression model development
WO2022221586A1 (en) * 2021-04-15 2022-10-20 Ideaya Biosciences, Inc. Combination therapy comprising a pkc inhibitor and a mek inhibitor
EP4577309A2 (en) * 2022-08-26 2025-07-02 Ideaya Biosciences, Inc. Methods of treating uveal melanoma with a pkc inhibitor

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5489608A (en) 1989-12-21 1996-02-06 Goedecke Aktiengesellschaft Indolocarbazole derivatives and the use thereof
US5475085A (en) 1991-02-07 1995-12-12 Molecumetics, Ltd. Conformationally restricted mimetics of beta turns and beta bulges and peptides containing the same
NO308798B1 (no) 1993-12-07 2000-10-30 Lilly Co Eli Proteinkinase-C-hemmere, anvendelse av samme for fremstilling av farmasøytika samt farmasøytisk formulering omfattende samme
US5545636A (en) 1993-12-23 1996-08-13 Eli Lilly And Company Protein kinase C inhibitors
ATE456367T1 (de) 1993-12-23 2010-02-15 Lilly Co Eli Proteinkinase c inhibitoren
ZA969646B (en) 1995-11-20 1998-05-18 Lilly Co Eli Protein kinase C inhibitor.
IL153817A0 (en) 2000-07-19 2003-07-31 Warner Lambert Co Oxygenated esters of 4-iodo phenylamino benzhydroxamic acids
US6645970B2 (en) 2000-11-07 2003-11-11 Novartis Ag Indolylmaleimide derivatives
PE20020544A1 (es) 2000-11-07 2002-07-30 Novartis Ag Derivados de indolilmaleimida
CA2478374C (en) 2002-03-13 2009-01-06 Eli M. Wallace N3 alkylated benzimidazole derivatives as mek inhibitors
AR039209A1 (es) 2002-04-03 2005-02-09 Novartis Ag Derivados de indolilmaleimida
US6930093B2 (en) * 2003-07-10 2005-08-16 Valeant Research & Development Use of ribofuranose derivatives against inflammatory bowel diseases
PT1761528E (pt) 2004-06-11 2008-04-15 Japan Tobacco Inc Derivados de 5-amino-2,4,7-trioxo-3,4,7,8-tetra-hidro-2hpirido[ 2,3-d]pirimidina e compostos relacionados para o tratamento do cancro
RU2500673C2 (ru) 2005-05-18 2013-12-10 Астразенека Аб Гетероциклические ингибиторы мек и способы их применения
US7781438B2 (en) 2005-07-11 2010-08-24 Novartis Ag Indolylmaleimide derivatives

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