JP2016214245A5 - - Google Patents
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- Publication number
- JP2016214245A5 JP2016214245A5 JP2016129697A JP2016129697A JP2016214245A5 JP 2016214245 A5 JP2016214245 A5 JP 2016214245A5 JP 2016129697 A JP2016129697 A JP 2016129697A JP 2016129697 A JP2016129697 A JP 2016129697A JP 2016214245 A5 JP2016214245 A5 JP 2016214245A5
- Authority
- JP
- Japan
- Prior art keywords
- eno1
- normalized
- level
- breast cancer
- rna transcript
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102100038910 Alpha-enolase Human genes 0.000 claims 36
- 101000882335 Homo sapiens Alpha-enolase Proteins 0.000 claims 36
- VLMZMRDOMOGGFA-WDBKCZKBSA-N festuclavine Chemical compound C1=CC([C@H]2C[C@H](CN(C)[C@@H]2C2)C)=C3C2=CNC3=C1 VLMZMRDOMOGGFA-WDBKCZKBSA-N 0.000 claims 36
- 238000000034 method Methods 0.000 claims 22
- 206010006187 Breast cancer Diseases 0.000 claims 15
- 208000026310 Breast neoplasm Diseases 0.000 claims 15
- 108091093088 Amplicon Proteins 0.000 claims 13
- 238000004393 prognosis Methods 0.000 claims 9
- 206010027476 Metastases Diseases 0.000 claims 5
- 238000004590 computer program Methods 0.000 claims 5
- 230000009401 metastasis Effects 0.000 claims 5
- 102000015694 estrogen receptors Human genes 0.000 claims 4
- 108010038795 estrogen receptors Proteins 0.000 claims 4
- 239000002299 complementary DNA Substances 0.000 claims 3
- 230000004083 survival effect Effects 0.000 claims 3
- 101001038034 Homo sapiens Lysophosphatidic acid receptor 6 Proteins 0.000 claims 2
- 102100040406 Lysophosphatidic acid receptor 6 Human genes 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 238000001574 biopsy Methods 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26376309P | 2009-11-23 | 2009-11-23 | |
| US61/263,763 | 2009-11-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Division JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018145578A Division JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016214245A JP2016214245A (ja) | 2016-12-22 |
| JP2016214245A5 true JP2016214245A5 (enExample) | 2017-03-30 |
Family
ID=44060376
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Active JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
| JP2016129697A Pending JP2016214245A (ja) | 2009-11-23 | 2016-06-30 | 癌の臨床転帰を予測する方法 |
| JP2018145578A Active JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
| JP2020218527A Pending JP2021058207A (ja) | 2009-11-23 | 2020-12-28 | 癌の臨床転帰を予測する方法 |
| JP2022123265A Pending JP2022166064A (ja) | 2009-11-23 | 2022-08-02 | 癌の臨床転帰を予測する方法 |
| JP2022129605A Pending JP2022169647A (ja) | 2009-11-23 | 2022-08-16 | 癌の臨床転帰を予測する方法 |
| JP2023213416A Active JP7823012B2 (ja) | 2009-11-23 | 2023-12-18 | 癌の臨床転帰を予測する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Active JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018145578A Active JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
| JP2020218527A Pending JP2021058207A (ja) | 2009-11-23 | 2020-12-28 | 癌の臨床転帰を予測する方法 |
| JP2022123265A Pending JP2022166064A (ja) | 2009-11-23 | 2022-08-02 | 癌の臨床転帰を予測する方法 |
| JP2022129605A Pending JP2022169647A (ja) | 2009-11-23 | 2022-08-16 | 癌の臨床転帰を予測する方法 |
| JP2023213416A Active JP7823012B2 (ja) | 2009-11-23 | 2023-12-18 | 癌の臨床転帰を予測する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20110123990A1 (enExample) |
| EP (4) | EP2504451B1 (enExample) |
| JP (7) | JP5964752B2 (enExample) |
| AU (1) | AU2010321829B2 (enExample) |
| CA (2) | CA2776751C (enExample) |
| DK (1) | DK2504451T3 (enExample) |
| ES (1) | ES2735993T3 (enExample) |
| HU (1) | HUE044374T2 (enExample) |
| IL (5) | IL219051A (enExample) |
| MX (3) | MX337650B (enExample) |
| NZ (1) | NZ599194A (enExample) |
| PL (1) | PL2504451T3 (enExample) |
| WO (1) | WO2011063274A2 (enExample) |
Families Citing this family (61)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| US7871769B2 (en) | 2004-04-09 | 2011-01-18 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| CA2585571C (en) * | 2004-11-05 | 2020-01-21 | Genomic Health, Inc. | Predicting response to chemotherapy using gene expression markers |
| US7888019B2 (en) | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| WO2009158620A2 (en) * | 2008-06-26 | 2009-12-30 | Dana-Farber Cancer Institute, Inc. | Signatures and determinants associated with metastasis methods of use thereof |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| DK177532B1 (en) | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
| MX337650B (es) * | 2009-11-23 | 2016-03-14 | Genomic Health Inc | Metodos para predecir el desenlace clinico del cancer. |
| ES3027507T3 (en) | 2010-01-11 | 2025-06-16 | Genomic Health Inc | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
| GB201009798D0 (en) | 2010-06-11 | 2010-07-21 | Immunovia Ab | Method,array and use thereof |
| CA2804391A1 (en) | 2010-07-07 | 2012-01-12 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| DK2598659T3 (en) | 2010-07-27 | 2015-05-26 | Genomic Health Inc | PROCEDURE FOR USING GENEPRESSION FOR DETERMINING PROSTATE CANCER FORECAST |
| WO2012030840A2 (en) | 2010-08-30 | 2012-03-08 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| US8916344B2 (en) | 2010-11-15 | 2014-12-23 | Exact Sciences Corporation | Methylation assay |
| US20140113297A1 (en) * | 2011-03-26 | 2014-04-24 | Oregon Health & Science University | Gene expression predictors of cancer prognosis |
| WO2012178087A1 (en) * | 2011-06-22 | 2012-12-27 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of bladder cancer |
| WO2013006495A2 (en) * | 2011-07-01 | 2013-01-10 | Dana-Farber Cancer Institute, Inc. | Methods of predicting prognosis in cancer |
| KR102003660B1 (ko) * | 2011-07-13 | 2019-07-24 | 더 멀티플 마이얼로머 리서치 파운데이션, 인크. | 데이터 수집 및 분배 방법 |
| CN104080924A (zh) * | 2011-08-16 | 2014-10-01 | 昂科赛特公司 | 用于治疗和诊断乳腺癌的方法和组合物 |
| CA2854805C (en) * | 2011-11-08 | 2021-04-27 | Genomic Health, Inc. | Method of predicting breast cancer prognosis |
| JP5805518B2 (ja) * | 2011-12-21 | 2015-11-04 | 株式会社島津製作所 | マルチプレックス大腸がんマーカーパネル |
| CA2863040C (en) | 2012-01-31 | 2022-04-19 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| GB201206323D0 (en) * | 2012-04-10 | 2012-05-23 | Immunovia Ab | Methods and arrays for use in the same |
| WO2013159099A2 (en) * | 2012-04-20 | 2013-10-24 | Memorial Sloan-Kettering Cancer Center | Gene expression profiles associated with metastatic breast cancer |
| US20150299799A1 (en) | 2012-10-05 | 2015-10-22 | Michael Sturzl | Method for Detecting an Increased Risk or Incidence of Colorectal Cancer |
| EP4190918A1 (en) | 2012-11-16 | 2023-06-07 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| ES2859645T3 (es) | 2013-03-14 | 2021-10-04 | Mayo Found Medical Education & Res | Detección de neoplasia |
| KR101672531B1 (ko) * | 2013-04-18 | 2016-11-17 | 주식회사 젠큐릭스 | 조기 유방암 예후 예측 진단용 유전자 마커 및 이의 용도 |
| CA2903878C (en) * | 2013-05-30 | 2020-10-27 | Genomic Health, Inc. | Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer |
| WO2014195032A1 (en) * | 2013-06-07 | 2014-12-11 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy of fulvestrant in cancer patients |
| WO2015138769A1 (en) * | 2014-03-12 | 2015-09-17 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for assessing patients with non-small cell lung cancer |
| WO2015175692A1 (en) | 2014-05-13 | 2015-11-19 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| US10570457B2 (en) | 2014-09-26 | 2020-02-25 | Medical Prognosis Institute A/S | Methods for predicting drug responsiveness |
| WO2016092299A1 (en) * | 2014-12-09 | 2016-06-16 | Medical Research Council | Methods and kits for predicting the response to therapy of cancer |
| WO2016160454A1 (en) | 2015-03-27 | 2016-10-06 | Exact Sciences Corporation | Detecting esophageal disorders |
| KR20250172724A (ko) | 2015-08-31 | 2025-12-09 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 위 신생물 검출 방법 |
| KR20250073555A (ko) | 2015-10-30 | 2025-05-27 | 이그잭트 사이언시즈 코포레이션 | 복합 증폭 검출 분석 및 혈장으로부터 dna의 분리 및 검출 방법 |
| CA3008273A1 (en) | 2015-12-18 | 2017-06-22 | Clear Gene, Inc. | Methods, compositions, kits and devices for rapid analysis of biological markers |
| CN116064796A (zh) | 2016-05-05 | 2023-05-05 | 精密科学公司 | 通过分析甲基化dna来检测肺肿瘤 |
| CN110225984A (zh) * | 2016-09-07 | 2019-09-10 | 科技研究局 | 鉴别癌症风险的方法和治疗选择 |
| US9725769B1 (en) | 2016-10-07 | 2017-08-08 | Oncology Venture ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| JP7289264B2 (ja) | 2017-01-27 | 2023-06-09 | エグザクト サイエンシーズ コーポレーション | メチル化ｄｎａの分析による結腸腫瘍の検出 |
| WO2018212192A1 (ja) * | 2017-05-18 | 2018-11-22 | 京都府公立大学法人 | 癌の予後及び／又は転移可能性を評価する方法及びマーカー |
| US12275994B2 (en) * | 2017-06-22 | 2025-04-15 | Clear Gene, Inc. | Methods and compositions for the analysis of cancer biomarkers |
| MX389484B (es) | 2017-11-13 | 2025-03-20 | The Multiple Myeloma Res Foundation Inc | Base de datos, de datos moleculares, omicos, de inmunoterapia, metabolicos, epigeneticos y clinicos, integrados |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| WO2019173647A1 (en) * | 2018-03-08 | 2019-09-12 | University Of Notre Dame Du Lac | Products for assessing colorectal cancer molecular subtype and risk of recurrence and for determining and adminstering treatment protocols based thereon |
| JP7199045B2 (ja) * | 2018-04-13 | 2023-01-05 | 国立大学法人大阪大学 | 乳癌の予後に関する情報の取得方法、乳癌の予後の判定装置及びコンピュータプログラム |
| JP7444376B2 (ja) * | 2018-09-21 | 2024-03-06 | 国立大学法人 東京大学 | がんの予後判定方法 |
| JP2019032334A (ja) * | 2018-10-03 | 2019-02-28 | イムノヴィア・アクチエボラーグ | 乳癌関連の疾患状態を決定する方法およびこの方法における使用のためのアレイ |
| KR102216645B1 (ko) * | 2018-10-29 | 2021-02-17 | 사회복지법인 삼성생명공익재단 | 폐암의 분자 아형 결정을 위한 바이오마커 패널 및 이의 용도 |
| WO2020118274A1 (en) * | 2018-12-08 | 2020-06-11 | Pfs Genomics, Inc. | Transcriptomic profiling for prognosis of breast cancer |
| CN113785076B (zh) * | 2019-05-03 | 2024-06-11 | 株式会社递希真 | 预测癌症预后的方法及其组合物 |
| CN111235270B (zh) * | 2019-08-29 | 2022-04-29 | 北京臻知医学科技有限责任公司 | 一种基于高通量测序法的肿瘤抗原表达检测引物及试剂盒 |
| US12165747B2 (en) * | 2020-01-23 | 2024-12-10 | The Broad Institute, Inc. | Molecular spatial mapping of metastatic tumor microenvironment |
| AU2022220330A1 (en) * | 2021-02-12 | 2023-09-14 | Mammogen, Inc. | Biomarkers for the diagnosis of breast cancer |
| WO2022192128A2 (en) * | 2021-03-08 | 2022-09-15 | Castle Biosciences, Inc. | Determining prognosis and treatment based on clinical-pathologic factors and continuous multigene-expression profile scores |
| CN117116345B (zh) * | 2023-07-24 | 2025-09-16 | 中国人民解放军军事科学院军事医学研究院 | 一种基于基因调控网络构建患者生存网络的方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7171311B2 (en) * | 2001-06-18 | 2007-01-30 | Rosetta Inpharmatics Llc | Methods of assigning treatment to breast cancer patients |
| DE60239535D1 (de) * | 2001-06-18 | 2011-05-05 | Rosetta Inpharmatics Llc | Diagnose und prognose von brustkrebspatientinnen |
| AU2002322280A1 (en) * | 2001-06-21 | 2003-01-21 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| DK2258872T3 (da) * | 2002-03-13 | 2013-11-18 | Genomic Health Inc | Genekspressionsprofilering i biopsier af tumorvæv |
| US20040067234A1 (en) * | 2002-07-11 | 2004-04-08 | Paz Einat | Isocitrate dehydrogenase and uses thereof |
| US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| EP3330875B1 (en) * | 2003-07-10 | 2021-12-01 | Genomic Health, Inc. | Expression profile algorithm and test for prognosing breast cancer recurrence |
| US8019552B2 (en) * | 2004-03-05 | 2011-09-13 | The Netherlands Cancer Institute | Classification of breast cancer patients using a combination of clinical criteria and informative genesets |
| JP2008515398A (ja) * | 2004-09-30 | 2008-05-15 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | 癌治療における治療の成功および再発しない生存を予測するための方法およびキット |
| KR20080004551A (ko) | 2005-04-01 | 2008-01-09 | 엔씨씨 테크놀로지 벤쳐스 피티이 리미티드 | 유방암 분류에 관한 재료 및 방법 |
| WO2006133460A2 (en) | 2005-06-09 | 2006-12-14 | Yale University | Methods for diagnosing and treating breast cancer based on a her/er ratio |
| US20070099209A1 (en) * | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US20070105133A1 (en) * | 2005-06-13 | 2007-05-10 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| TWI304443B (en) * | 2005-12-30 | 2008-12-21 | Nat Health Research Institutes | Alpha-enolase specific antibody and method of use |
| US7888019B2 (en) * | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| JP2010524456A (ja) * | 2007-04-16 | 2010-07-22 | イプソゲン | 乳癌に罹患している雌哺乳動物に対する臨床転帰の傾向を評価する方法 |
| WO2008150512A2 (en) * | 2007-06-04 | 2008-12-11 | University Of Louisville Research Foundation, Inc. | Methods for identifying an increased likelihood of recurrence of breast cancer |
| WO2009095319A1 (en) * | 2008-01-28 | 2009-08-06 | Siemens Healthcare Diagnostics Gmbh | Cancer prognosis by majority voting |
| WO2009132928A2 (en) * | 2008-05-02 | 2009-11-05 | Siemens Healthcare Diagnostics Gmbh | Molecular markers for cancer prognosis |
| ES2482692T3 (es) * | 2008-05-12 | 2014-08-04 | Genomic Health, Inc. | Pruebas para predecir la receptividad de pacientes con cáncer a opciones de tratamiento con quimioterapia |
| MX337650B (es) * | 2009-11-23 | 2016-03-14 | Genomic Health Inc | Metodos para predecir el desenlace clinico del cancer. |
-
2010
- 2010-11-19 MX MX2012005822A patent/MX337650B/es active IP Right Grant
- 2010-11-19 EP EP10832289.2A patent/EP2504451B1/en active Active
- 2010-11-19 PL PL10832289T patent/PL2504451T3/pl unknown
- 2010-11-19 ES ES10832289T patent/ES2735993T3/es active Active
- 2010-11-19 EP EP19175741.8A patent/EP3556867A1/en not_active Withdrawn
- 2010-11-19 EP EP20177718.2A patent/EP3739060A1/en not_active Withdrawn
- 2010-11-19 CA CA2776751A patent/CA2776751C/en active Active
- 2010-11-19 MX MX2016003089A patent/MX363817B/es unknown
- 2010-11-19 HU HUE10832289 patent/HUE044374T2/hu unknown
- 2010-11-19 DK DK10832289.2T patent/DK2504451T3/da active
- 2010-11-19 US US12/950,732 patent/US20110123990A1/en not_active Abandoned
- 2010-11-19 CA CA3043089A patent/CA3043089A1/en not_active Withdrawn
- 2010-11-19 WO PCT/US2010/057490 patent/WO2011063274A2/en not_active Ceased
- 2010-11-19 NZ NZ599194A patent/NZ599194A/en unknown
- 2010-11-19 EP EP23213439.5A patent/EP4350001A3/en active Pending
- 2010-11-19 MX MX2019003811A patent/MX391499B/es unknown
- 2010-11-19 JP JP2012540103A patent/JP5964752B2/ja active Active
- 2010-11-19 AU AU2010321829A patent/AU2010321829B2/en active Active
-
2012
- 2012-04-04 IL IL219051A patent/IL219051A/en active IP Right Grant
-
2016
- 2016-06-30 JP JP2016129697A patent/JP2016214245A/ja active Pending
- 2016-11-23 IL IL249159A patent/IL249159A0/en unknown
-
2017
- 2017-02-03 US US15/423,977 patent/US20170211154A1/en not_active Abandoned
-
2018
- 2018-01-21 IL IL257063A patent/IL257063B/en active IP Right Grant
- 2018-08-02 JP JP2018145578A patent/JP7042717B2/ja active Active
-
2019
- 2019-01-03 IL IL264072A patent/IL264072B/en active IP Right Grant
- 2019-01-09 US US16/243,207 patent/US20190241967A1/en not_active Abandoned
-
2020
- 2020-08-04 IL IL276487A patent/IL276487B/en unknown
- 2020-09-11 US US17/018,143 patent/US20210062275A1/en not_active Abandoned
- 2020-12-28 JP JP2020218527A patent/JP2021058207A/ja active Pending
-
2022
- 2022-08-02 JP JP2022123265A patent/JP2022166064A/ja active Pending
- 2022-08-16 JP JP2022129605A patent/JP2022169647A/ja active Pending
-
2023
- 2023-12-18 JP JP2023213416A patent/JP7823012B2/ja active Active
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