JP2010538609A5 - - Google Patents
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- JP2010538609A5 JP2010538609A5 JP2010524215A JP2010524215A JP2010538609A5 JP 2010538609 A5 JP2010538609 A5 JP 2010538609A5 JP 2010524215 A JP2010524215 A JP 2010524215A JP 2010524215 A JP2010524215 A JP 2010524215A JP 2010538609 A5 JP2010538609 A5 JP 2010538609A5
- Authority
- JP
- Japan
- Prior art keywords
- cancer
- grade
- subject
- sample
- tumor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 206010028980 Neoplasm Diseases 0.000 claims 28
- 238000000034 method Methods 0.000 claims 19
- 201000011510 cancer Diseases 0.000 claims 17
- 238000004393 prognosis Methods 0.000 claims 5
- 102000011682 Centromere Protein A Human genes 0.000 claims 4
- 108010076303 Centromere Protein A Proteins 0.000 claims 4
- 101001096541 Homo sapiens Rac GTPase-activating protein 1 Proteins 0.000 claims 4
- 101000575639 Homo sapiens Ribonucleoside-diphosphate reductase subunit M2 Proteins 0.000 claims 4
- 101000601441 Homo sapiens Serine/threonine-protein kinase Nek2 Proteins 0.000 claims 4
- 102100037414 Rac GTPase-activating protein 1 Human genes 0.000 claims 4
- 102100026006 Ribonucleoside-diphosphate reductase subunit M2 Human genes 0.000 claims 4
- 102100037703 Serine/threonine-protein kinase Nek2 Human genes 0.000 claims 4
- 238000003556 assay Methods 0.000 claims 4
- 230000000875 corresponding effect Effects 0.000 claims 4
- 238000003752 polymerase chain reaction Methods 0.000 claims 3
- 206010006187 Breast cancer Diseases 0.000 claims 2
- 208000026310 Breast neoplasm Diseases 0.000 claims 2
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 claims 2
- 208000037396 Intraductal Noninfiltrating Carcinoma Diseases 0.000 claims 2
- 230000002596 correlated effect Effects 0.000 claims 2
- 208000028715 ductal breast carcinoma in situ Diseases 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 238000001959 radiotherapy Methods 0.000 claims 2
- 206010073094 Intraductal proliferative breast lesion Diseases 0.000 claims 1
- 210000000481 breast Anatomy 0.000 claims 1
- 238000002512 chemotherapy Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 239000012188 paraffin wax Substances 0.000 claims 1
- 238000003753 real-time PCR Methods 0.000 claims 1
- 238000003757 reverse transcription PCR Methods 0.000 claims 1
- 238000001356 surgical procedure Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US97052907P | 2007-09-06 | 2007-09-06 | |
| PCT/US2008/075528 WO2009108215A1 (en) | 2007-09-06 | 2008-09-06 | Tumor grading and cancer prognosis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014187715A Division JP2015057055A (ja) | 2007-09-06 | 2014-09-16 | 腫瘍グレード分類と癌の予後診断 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2010538609A JP2010538609A (ja) | 2010-12-16 |
| JP2010538609A5 true JP2010538609A5 (enExample) | 2011-10-27 |
Family
ID=40790735
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010524215A Pending JP2010538609A (ja) | 2007-09-06 | 2008-09-06 | 腫瘍グレード分類と癌の予後診断 |
| JP2014187715A Pending JP2015057055A (ja) | 2007-09-06 | 2014-09-16 | 腫瘍グレード分類と癌の予後診断 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014187715A Pending JP2015057055A (ja) | 2007-09-06 | 2014-09-16 | 腫瘍グレード分類と癌の予後診断 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US9447470B2 (enExample) |
| EP (1) | EP2195467B1 (enExample) |
| JP (2) | JP2010538609A (enExample) |
| CN (1) | CN102395682B (enExample) |
| CA (1) | CA2698569A1 (enExample) |
| ES (1) | ES2618353T3 (enExample) |
| WO (1) | WO2009108215A1 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20030198972A1 (en) | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
| US9856533B2 (en) | 2003-09-19 | 2018-01-02 | Biotheranostics, Inc. | Predicting breast cancer treatment outcome |
| JP2008545431A (ja) * | 2005-06-03 | 2008-12-18 | アビアラデックス，インコーポレイティド | 腫瘍および組織の同定 |
| WO2010151731A1 (en) * | 2009-06-26 | 2010-12-29 | University Of Utah Research Foundation | Materials and methods for the identification of drug-resistant cancers and treatment of same |
| EP2648762B1 (en) | 2010-12-09 | 2018-02-21 | Biotheranostics, Inc. | Post-treatment breast cancer prognosis |
| US20120271553A1 (en) * | 2011-04-22 | 2012-10-25 | Ge Global Research | Analyzing the expression of biomarkers in cells with clusters |
| US9470693B2 (en) | 2012-05-18 | 2016-10-18 | University Of North Dakota | Method for quantifying proteins and isoforms thereof |
| WO2013177245A2 (en) * | 2012-05-22 | 2013-11-28 | Nanostring Technologies, Inc. | Nano46 genes and methods to predict breast cancer outcome |
| WO2013190081A1 (en) * | 2012-06-22 | 2013-12-27 | Proyecto De Biomedicina Cima, S.L. | Methods and reagents for the prognosis of cancer |
| JP2016537010A (ja) * | 2013-09-09 | 2016-12-01 | ブリティッシュ コロンビア キャンサー エージェンシー ブランチ | 予後を予測するための方法及びキット、並びに、放射線照射療法を用いた乳癌の治療方法及びキット |
| BR112016005225B1 (pt) | 2013-09-11 | 2023-11-14 | Bio Theranostics, Inc | Métodos para avaliar câncer de mama em um indivíduo |
| WO2015184182A1 (en) * | 2014-05-29 | 2015-12-03 | Biotheranostics, Inc | Predicting likelihood of response to combination therapy |
| US11530448B2 (en) | 2015-11-13 | 2022-12-20 | Biotheranostics, Inc. | Integration of tumor characteristics with breast cancer index |
| CN107119055A (zh) * | 2017-05-18 | 2017-09-01 | 南京中医药大学 | 分子标志物bub1b基因及其应用 |
| CN110021433B (zh) * | 2017-08-30 | 2023-11-17 | 中山大学 | 一种用于精准预测胃肠胰神经内分泌肿瘤患者预后的系统 |
| MX2021001857A (es) * | 2018-08-17 | 2021-10-13 | Genentech Inc Star | Metodos de diagnostico y terapeuticos para el tratamiento del cancer de mama. |
| CN109706160A (zh) * | 2019-02-22 | 2019-05-03 | 广西医科大学 | 重组人蛋白激酶Nek2蛋白表达和纯化方法 |
| KR102405973B1 (ko) * | 2019-09-20 | 2022-06-07 | 고려대학교 산학협력단 | 유방암 초음파 영상과 유전자 정보를 이용한 유방암 치료법 선택을 위한 정보를 제공하는 방법 |
| KR102508210B1 (ko) * | 2020-10-16 | 2023-03-10 | 고려대학교 산학협력단 | 유방암 초음파 영상을 이용한 dna 유전자 정보를 제공하는 방법 |
| CN115029437A (zh) * | 2022-04-28 | 2022-09-09 | 深圳市陆为生物技术有限公司 | 检测样本中生物标志物的试剂在制备乳腺癌患者化疗响应评估产品中的应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5545522A (en) | 1989-09-22 | 1996-08-13 | Van Gelder; Russell N. | Process for amplifying a target polynucleotide sequence using a single primer-promoter complex |
| AU1820100A (en) | 1998-11-13 | 2000-06-05 | Pro Duct Health, Inc. | Devices and methods to identify ductal orifices during nipple aspiration |
| US20030228575A1 (en) * | 2001-01-31 | 2003-12-11 | Yuk Ming Dennis Lo | Combination of circulating epstein-barr virus (EBV) DNA in the serum or plasma of patients and a method to assess EBV subtypes for the prediction and detection of epstein-barr virus associated cancers |
| WO2002092854A2 (en) * | 2001-05-16 | 2002-11-21 | Novartis Ag | Genes expressed in breast cancer as prognostic and therapeutic targets |
| JP2005503779A (ja) * | 2001-06-10 | 2005-02-10 | アイアールエム，エルエルシー | 致死性の高い癌の分子シグネチャー |
| US20030198972A1 (en) * | 2001-12-21 | 2003-10-23 | Erlander Mark G. | Grading of breast cancer |
| JP4680898B2 (ja) * | 2003-06-24 | 2011-05-11 | ジェノミック ヘルス， インコーポレイテッド | 癌再発の可能性の予測 |
| EP3330875B1 (en) * | 2003-07-10 | 2021-12-01 | Genomic Health, Inc. | Expression profile algorithm and test for prognosing breast cancer recurrence |
| EP1673470A2 (en) * | 2003-09-18 | 2006-06-28 | Genmab A/S | Differentially expressed tumour-specific polypeptides for use in the diagnosis and treatment of cancer |
| US7504214B2 (en) | 2003-09-19 | 2009-03-17 | Biotheranostics, Inc. | Predicting outcome with tamoxifen in breast cancer |
| CA2539107A1 (en) | 2003-09-19 | 2005-03-31 | Arcturus Bioscience, Inc. | Predicting breast cancer treatment outcome |
| US9856533B2 (en) | 2003-09-19 | 2018-01-02 | Biotheranostics, Inc. | Predicting breast cancer treatment outcome |
| US7498693B2 (en) | 2004-02-18 | 2009-03-03 | Diversified Technologies, Inc. | More compact and higher reliability power source system |
| EP1880335A1 (en) | 2005-05-13 | 2008-01-23 | Universite Libre De Bruxelles | Gene-based algorithmic cancer prognosis |
| JP2008545431A (ja) * | 2005-06-03 | 2008-12-18 | アビアラデックス，インコーポレイティド | 腫瘍および組織の同定 |
-
2008
- 2008-09-06 CN CN200880114588.6A patent/CN102395682B/zh active Active
- 2008-09-06 ES ES08872935T patent/ES2618353T3/es active Active
- 2008-09-06 JP JP2010524215A patent/JP2010538609A/ja active Pending
- 2008-09-06 EP EP08872935.5A patent/EP2195467B1/en active Active
- 2008-09-06 WO PCT/US2008/075528 patent/WO2009108215A1/en not_active Ceased
- 2008-09-06 CA CA2698569A patent/CA2698569A1/en not_active Abandoned
-
2010
- 2010-03-06 US US12/718,973 patent/US9447470B2/en active Active
-
2014
- 2014-09-16 JP JP2014187715A patent/JP2015057055A/ja active Pending
-
2017
- 2017-11-08 US US15/807,456 patent/US11021754B2/en active Active
-
2021
- 2021-04-23 US US17/239,207 patent/US12492432B2/en active Active
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