JP2016507233A5 - - Google Patents
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- JP2016507233A5 JP2016507233A5 JP2015555726A JP2015555726A JP2016507233A5 JP 2016507233 A5 JP2016507233 A5 JP 2016507233A5 JP 2015555726 A JP2015555726 A JP 2015555726A JP 2015555726 A JP2015555726 A JP 2015555726A JP 2016507233 A5 JP2016507233 A5 JP 2016507233A5
- Authority
- JP
- Japan
- Prior art keywords
- gene
- genes
- crh
- magea3
- slc1a6
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000623 proteins and genes Proteins 0.000 claims 82
- 101000895481 Homo sapiens Corticoliberin Proteins 0.000 claims 64
- 102100021752 Corticoliberin Human genes 0.000 claims 63
- 101001005719 Homo sapiens Melanoma-associated antigen 3 Proteins 0.000 claims 63
- 102100025082 Melanoma-associated antigen 3 Human genes 0.000 claims 63
- 230000014509 gene expression Effects 0.000 claims 63
- 101000866308 Homo sapiens Excitatory amino acid transporter 4 Proteins 0.000 claims 62
- 101000768069 Homo sapiens Annexin A10 Proteins 0.000 claims 59
- 101000994460 Homo sapiens Keratin, type I cytoskeletal 20 Proteins 0.000 claims 59
- 102100028117 Annexin A10 Human genes 0.000 claims 58
- 102000012985 SLC1A6 Human genes 0.000 claims 58
- 102100032700 Keratin, type I cytoskeletal 20 Human genes 0.000 claims 56
- 102100032215 Cathepsin E Human genes 0.000 claims 51
- 101000869031 Homo sapiens Cathepsin E Proteins 0.000 claims 51
- 101001139112 Homo sapiens Krueppel-like factor 9 Proteins 0.000 claims 48
- 101001095308 Homo sapiens Periostin Proteins 0.000 claims 48
- 102100020684 Krueppel-like factor 9 Human genes 0.000 claims 48
- 102100037765 Periostin Human genes 0.000 claims 48
- 102100030962 Protein MCM10 homolog Human genes 0.000 claims 44
- 101000688355 Homo sapiens Protein phosphatase 1 regulatory subunit 14D Proteins 0.000 claims 43
- 102100024202 Protein phosphatase 1 regulatory subunit 14D Human genes 0.000 claims 43
- 102100031838 Protein AHNAK2 Human genes 0.000 claims 42
- 101000583797 Homo sapiens Protein MCM10 homolog Proteins 0.000 claims 40
- XXQGYGJZNMSSFD-UHFFFAOYSA-N 2-[2-(dimethylcarbamoyl)phenoxy]acetic acid Chemical compound CN(C)C(=O)C1=CC=CC=C1OCC(O)=O XXQGYGJZNMSSFD-UHFFFAOYSA-N 0.000 claims 39
- 102100022443 CXADR-like membrane protein Human genes 0.000 claims 39
- 101000775052 Homo sapiens Protein AHNAK2 Proteins 0.000 claims 39
- 102100024207 Transcription factor COE1 Human genes 0.000 claims 36
- 101000737574 Homo sapiens Complement factor H Proteins 0.000 claims 32
- 101000909637 Homo sapiens Transcription factor COE1 Proteins 0.000 claims 32
- 239000000523 sample Substances 0.000 claims 31
- 102100035432 Complement factor H Human genes 0.000 claims 30
- 101000577881 Homo sapiens Macrophage metalloelastase Proteins 0.000 claims 29
- 206010005003 Bladder cancer Diseases 0.000 claims 24
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 24
- 201000005112 urinary bladder cancer Diseases 0.000 claims 24
- 101150002416 Igf2 gene Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 20
- 101001076292 Homo sapiens Insulin-like growth factor II Proteins 0.000 claims 17
- 102100025947 Insulin-like growth factor II Human genes 0.000 claims 17
- 108020004999 messenger RNA Proteins 0.000 claims 13
- 239000003153 chemical reaction reagent Substances 0.000 claims 8
- 239000002299 complementary DNA Substances 0.000 claims 8
- 101150101095 Mmp12 gene Proteins 0.000 claims 7
- 102000004169 proteins and genes Human genes 0.000 claims 5
- 101150030967 CFH gene Proteins 0.000 claims 4
- 101150070744 EBF1 gene Proteins 0.000 claims 4
- 101150036749 Mcm10 gene Proteins 0.000 claims 4
- 108091034117 Oligonucleotide Proteins 0.000 claims 4
- 101150063158 AHNAK2 gene Proteins 0.000 claims 3
- 101150023743 KLF9 gene Proteins 0.000 claims 3
- 230000003247 decreasing effect Effects 0.000 claims 3
- 238000002271 resection Methods 0.000 claims 3
- -1 AHNK2 Proteins 0.000 claims 2
- 101710106279 Cyclin-dependent kinase 1 Proteins 0.000 claims 2
- 108010008599 Forkhead Box Protein M1 Proteins 0.000 claims 2
- 102100023374 Forkhead box protein M1 Human genes 0.000 claims 2
- 101001027621 Homo sapiens Kinesin-like protein KIF20A Proteins 0.000 claims 2
- 102100037694 Kinesin-like protein KIF20A Human genes 0.000 claims 2
- 102100024299 Maternal embryonic leucine zipper kinase Human genes 0.000 claims 2
- 101710154611 Maternal embryonic leucine zipper kinase Proteins 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000003745 diagnosis Methods 0.000 claims 2
- 238000012277 endoscopic treatment Methods 0.000 claims 2
- 238000000338 in vitro Methods 0.000 claims 2
- 238000012544 monitoring process Methods 0.000 claims 2
- 238000002560 therapeutic procedure Methods 0.000 claims 2
- 210000002700 urine Anatomy 0.000 claims 2
- 108700026220 vif Genes Proteins 0.000 claims 2
- 239000003550 marker Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP13382030.8 | 2013-01-31 | ||
| EP13382030.8A EP2762574A1 (en) | 2013-01-31 | 2013-01-31 | Non-invasive diagnostic method for diagnosing bladder cancer |
| PCT/EP2014/051939 WO2014118334A1 (en) | 2013-01-31 | 2014-01-31 | Non-invasive diagnostic method for diagnosing bladder cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016507233A JP2016507233A (ja) | 2016-03-10 |
| JP2016507233A5 true JP2016507233A5 (enExample) | 2017-03-09 |
Family
ID=47877961
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015555726A Pending JP2016507233A (ja) | 2013-01-31 | 2014-01-31 | 膀胱癌を診断するための非侵襲的診断法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9902998B2 (enExample) |
| EP (3) | EP2762574A1 (enExample) |
| JP (1) | JP2016507233A (enExample) |
| CN (1) | CN105229169A (enExample) |
| AU (1) | AU2014211392A1 (enExample) |
| CA (1) | CA2900022C (enExample) |
| IL (1) | IL240310A0 (enExample) |
| WO (1) | WO2014118334A1 (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11939634B2 (en) | 2010-05-18 | 2024-03-26 | Natera, Inc. | Methods for simultaneous amplification of target loci |
| US10202653B2 (en) | 2012-04-20 | 2019-02-12 | Cepheid | Compositions and methods for detecting markers associated with bladder cancer |
| JP2016513961A (ja) | 2013-03-06 | 2016-05-19 | セファイド | 膀胱癌を検出する方法 |
| US12492429B2 (en) | 2014-04-21 | 2025-12-09 | Natera, Inc. | Detecting mutations and ploidy in chromosomal segments |
| CN105368959B (zh) * | 2015-12-15 | 2019-01-04 | 甘肃中天羊业股份有限公司 | Anxa10基因作为绵羊免疫性状的分子标记及其应用 |
| CL2016003434A1 (es) * | 2016-12-30 | 2018-11-23 | Pontificia Univ Catolia De Chile | Método ex vivo de pronóstico de metástasis en cáncer de próstata |
| CN106916887B (zh) * | 2017-02-13 | 2018-06-29 | 徐州市中心医院 | Erh基因在制备膀胱癌诊治产品中的应用 |
| WO2018218737A1 (zh) * | 2017-06-01 | 2018-12-06 | 立森印迹诊断技术（无锡）有限公司 | 一种印记基因在膀胱肿瘤中的分级模型及其组成的系统 |
| WO2018219342A1 (zh) * | 2017-06-01 | 2018-12-06 | 立森印迹诊断技术有限公司 | 一种印记基因分级模型和诊断方法及其应用 |
| CN107766695B (zh) * | 2017-10-20 | 2019-03-08 | 中国科学院北京基因组研究所 | 一种获取外周血基因模型训练数据的方法及装置 |
| US12084720B2 (en) | 2017-12-14 | 2024-09-10 | Natera, Inc. | Assessing graft suitability for transplantation |
| US12024738B2 (en) * | 2018-04-14 | 2024-07-02 | Natera, Inc. | Methods for cancer detection and monitoring |
| CN108866194B (zh) * | 2018-08-16 | 2021-03-26 | 杭州可帮基因科技有限公司 | 一组用于膀胱癌检测的基因及其应用 |
| CN111154879A (zh) * | 2020-03-06 | 2020-05-15 | 北京恩泽康泰生物科技有限公司 | 用于膀胱癌诊断或复发监控的生物标志物及试剂盒 |
| CA3186291A1 (en) * | 2020-06-10 | 2021-12-16 | Board Of Regents, The University Of Texas System | Method for determining risk of pre-term birth |
| CN112680522B (zh) * | 2021-01-15 | 2023-03-17 | 杭州可帮基因科技有限公司 | 一种检测膀胱癌的试剂盒 |
| KR102632423B1 (ko) * | 2021-02-26 | 2024-01-31 | 충북대학교 산학협력단 | 비근침윤성 방광암의 예후 예측을 위한 바이오마커 및 이의 용도 |
| KR102500377B1 (ko) | 2021-05-11 | 2023-02-16 | 재단법인 아산사회복지재단 | Fos 또는 cdk1 유전자 활성화를 통해 기능 향상된 줄기세포를 이용한 배뇨 장애 질환 치료 용도 |
| CN114240839B (zh) * | 2021-11-17 | 2023-04-07 | 东莞市人民医院 | 基于深度学习的膀胱肿瘤肌层侵犯预测方法及相关装置 |
| CN116024345B (zh) * | 2023-01-12 | 2023-12-01 | 上海仁度生物科技股份有限公司 | 膀胱癌的实时荧光核酸恒温扩增检测试剂盒及其专用引物和探针 |
| CN117670883B (zh) * | 2024-01-31 | 2024-05-07 | 中国医学科学院北京协和医院 | 一种鉴别高低级别膀胱癌的方法、设备和系统 |
| CN119410773B (zh) * | 2024-11-01 | 2025-07-25 | 上海爱谱蒂康生物科技有限公司 | 一种生物标志物组合及其在预测膀胱癌风险中的应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5512437A (en) * | 1994-03-01 | 1996-04-30 | Ludwig Institute For Cancer Research | Method for determining head and neck squamous cell carcinomas, prostate carcinomas, and bladder tumors by assaying for mage-3 |
| ES2304306B1 (es) * | 2007-03-20 | 2009-07-07 | Indas Biotech, S.L.U. | Metodo de diagnostico y/o pronostico de cancer vesical. |
| ES2323927B1 (es) | 2007-03-30 | 2010-05-14 | Laboratorios Salvat, S.A. | Metodo in vitro no invasivo para detectar carcinoma transicional de vejiga. |
| US10202653B2 (en) * | 2012-04-20 | 2019-02-12 | Cepheid | Compositions and methods for detecting markers associated with bladder cancer |
-
2013
- 2013-01-31 EP EP13382030.8A patent/EP2762574A1/en not_active Withdrawn
-
2014
- 2014-01-31 EP EP14701798.2A patent/EP2951315B1/en active Active
- 2014-01-31 EP EP22171771.3A patent/EP4060048A3/en active Pending
- 2014-01-31 US US14/765,271 patent/US9902998B2/en active Active
- 2014-01-31 CA CA2900022A patent/CA2900022C/en active Active
- 2014-01-31 JP JP2015555726A patent/JP2016507233A/ja active Pending
- 2014-01-31 CN CN201480011550.1A patent/CN105229169A/zh active Pending
- 2014-01-31 AU AU2014211392A patent/AU2014211392A1/en not_active Abandoned
- 2014-01-31 WO PCT/EP2014/051939 patent/WO2014118334A1/en not_active Ceased
-
2015
- 2015-08-02 IL IL240310A patent/IL240310A0/en unknown
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