JP2016214245A5 - - Google Patents
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- Publication number
- JP2016214245A5 JP2016214245A5 JP2016129697A JP2016129697A JP2016214245A5 JP 2016214245 A5 JP2016214245 A5 JP 2016214245A5 JP 2016129697 A JP2016129697 A JP 2016129697A JP 2016129697 A JP2016129697 A JP 2016129697A JP 2016214245 A5 JP2016214245 A5 JP 2016214245A5
- Authority
- JP
- Japan
- Prior art keywords
- eno1
- normalized
- level
- breast cancer
- rna transcript
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 102100038910 Alpha-enolase Human genes 0.000 claims 36
- 101000882335 Homo sapiens Alpha-enolase Proteins 0.000 claims 36
- VLMZMRDOMOGGFA-WDBKCZKBSA-N festuclavine Chemical compound C1=CC([C@H]2C[C@H](CN(C)[C@@H]2C2)C)=C3C2=CNC3=C1 VLMZMRDOMOGGFA-WDBKCZKBSA-N 0.000 claims 36
- 238000000034 method Methods 0.000 claims 22
- 206010006187 Breast cancer Diseases 0.000 claims 15
- 208000026310 Breast neoplasm Diseases 0.000 claims 15
- 108091093088 Amplicon Proteins 0.000 claims 13
- 238000004393 prognosis Methods 0.000 claims 9
- 206010027476 Metastases Diseases 0.000 claims 5
- 238000004590 computer program Methods 0.000 claims 5
- 230000009401 metastasis Effects 0.000 claims 5
- 102000015694 estrogen receptors Human genes 0.000 claims 4
- 108010038795 estrogen receptors Proteins 0.000 claims 4
- 239000002299 complementary DNA Substances 0.000 claims 3
- 230000004083 survival effect Effects 0.000 claims 3
- 101001038034 Homo sapiens Lysophosphatidic acid receptor 6 Proteins 0.000 claims 2
- 102100040406 Lysophosphatidic acid receptor 6 Human genes 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 238000001574 biopsy Methods 0.000 claims 1
- 238000010839 reverse transcription Methods 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26376309P | 2009-11-23 | 2009-11-23 | |
| US61/263,763 | 2009-11-23 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Division JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018145578A Division JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016214245A JP2016214245A (ja) | 2016-12-22 |
| JP2016214245A5 true JP2016214245A5 (cg-RX-API-DMAC7.html) | 2017-03-30 |
Family
ID=44060376
Family Applications (7)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Active JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
| JP2016129697A Pending JP2016214245A (ja) | 2009-11-23 | 2016-06-30 | 癌の臨床転帰を予測する方法 |
| JP2018145578A Active JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
| JP2020218527A Pending JP2021058207A (ja) | 2009-11-23 | 2020-12-28 | 癌の臨床転帰を予測する方法 |
| JP2022123265A Pending JP2022166064A (ja) | 2009-11-23 | 2022-08-02 | 癌の臨床転帰を予測する方法 |
| JP2022129605A Pending JP2022169647A (ja) | 2009-11-23 | 2022-08-16 | 癌の臨床転帰を予測する方法 |
| JP2023213416A Pending JP2024037948A (ja) | 2009-11-23 | 2023-12-18 | 癌の臨床転帰を予測する方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012540103A Active JP5964752B2 (ja) | 2009-11-23 | 2010-11-19 | 癌の臨床転帰を予測する方法 |
Family Applications After (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018145578A Active JP7042717B2 (ja) | 2009-11-23 | 2018-08-02 | 癌の臨床転帰を予測する方法 |
| JP2020218527A Pending JP2021058207A (ja) | 2009-11-23 | 2020-12-28 | 癌の臨床転帰を予測する方法 |
| JP2022123265A Pending JP2022166064A (ja) | 2009-11-23 | 2022-08-02 | 癌の臨床転帰を予測する方法 |
| JP2022129605A Pending JP2022169647A (ja) | 2009-11-23 | 2022-08-16 | 癌の臨床転帰を予測する方法 |
| JP2023213416A Pending JP2024037948A (ja) | 2009-11-23 | 2023-12-18 | 癌の臨床転帰を予測する方法 |
Country Status (13)
| Country | Link |
|---|---|
| US (4) | US20110123990A1 (cg-RX-API-DMAC7.html) |
| EP (4) | EP4350001A3 (cg-RX-API-DMAC7.html) |
| JP (7) | JP5964752B2 (cg-RX-API-DMAC7.html) |
| AU (1) | AU2010321829B2 (cg-RX-API-DMAC7.html) |
| CA (2) | CA2776751C (cg-RX-API-DMAC7.html) |
| DK (1) | DK2504451T3 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2735993T3 (cg-RX-API-DMAC7.html) |
| HU (1) | HUE044374T2 (cg-RX-API-DMAC7.html) |
| IL (5) | IL219051A (cg-RX-API-DMAC7.html) |
| MX (3) | MX391499B (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ599194A (cg-RX-API-DMAC7.html) |
| PL (1) | PL2504451T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011063274A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040231909A1 (en) | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| EP2163650B1 (en) | 2004-04-09 | 2015-08-05 | Genomic Health, Inc. | Gene expression markers for predicting response to chemotherapy |
| PL1836629T3 (pl) * | 2004-11-05 | 2020-06-15 | Genomic Health, Inc. | Przewidywanie odpowiedzi na chemioterapię z zastosowaniem markerów ekspresji genu |
| US7888019B2 (en) | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| CN102132160A (zh) * | 2008-06-26 | 2011-07-20 | 达纳-法伯癌症研究院有限公司 | 与转移有关的信号和决定子以及它们的使用方法及用途 |
| US20120041274A1 (en) | 2010-01-07 | 2012-02-16 | Myriad Genetics, Incorporated | Cancer biomarkers |
| DK177532B1 (en) | 2009-09-17 | 2013-09-08 | Bio Bedst Aps | Medical use of sPLA2 hydrolysable liposomes |
| AU2010321829B2 (en) * | 2009-11-23 | 2015-07-30 | Genomic Health, Inc. | Methods to predict clinical outcome of cancer |
| NZ705645A (en) | 2010-01-11 | 2016-05-27 | Genomic Health Inc | Method to use gene expression to determine likelihood of clinical outcome of renal cancer |
| GB201009798D0 (en) | 2010-06-11 | 2010-07-21 | Immunovia Ab | Method,array and use thereof |
| EP3812469A1 (en) | 2010-07-07 | 2021-04-28 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| SG186940A1 (en) | 2010-07-27 | 2013-02-28 | Genomic Health Inc | Method for using gene expression to determine prognosis of prostate cancer |
| US9605319B2 (en) | 2010-08-30 | 2017-03-28 | Myriad Genetics, Inc. | Gene signatures for cancer diagnosis and prognosis |
| US8916344B2 (en) | 2010-11-15 | 2014-12-23 | Exact Sciences Corporation | Methylation assay |
| US8361720B2 (en) | 2010-11-15 | 2013-01-29 | Exact Sciences Corporation | Real time cleavage assay |
| US20140113297A1 (en) * | 2011-03-26 | 2014-04-24 | Oregon Health & Science University | Gene expression predictors of cancer prognosis |
| WO2012178087A1 (en) * | 2011-06-22 | 2012-12-27 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of bladder cancer |
| WO2013006495A2 (en) * | 2011-07-01 | 2013-01-10 | Dana-Farber Cancer Institute, Inc. | Methods of predicting prognosis in cancer |
| KR102003660B1 (ko) * | 2011-07-13 | 2019-07-24 | 더 멀티플 마이얼로머 리서치 파운데이션, 인크. | 데이터 수집 및 분배 방법 |
| WO2013025952A2 (en) * | 2011-08-16 | 2013-02-21 | Oncocyte Corporation | Methods and compositions for the treatment and diagnosis of breast cancer |
| EP2776830B1 (en) * | 2011-11-08 | 2018-05-09 | Genomic Health, Inc. | Method of predicting breast cancer prognosis |
| JP5805518B2 (ja) * | 2011-12-21 | 2015-11-04 | 株式会社島津製作所 | マルチプレックス大腸がんマーカーパネル |
| HK1201881A1 (en) | 2012-01-31 | 2015-09-11 | Genomic Health, Inc. | Gene expression profile algorithm and test for determining prognosis of prostate cancer |
| GB201206323D0 (en) * | 2012-04-10 | 2012-05-23 | Immunovia Ab | Methods and arrays for use in the same |
| WO2013159099A2 (en) * | 2012-04-20 | 2013-10-24 | Memorial Sloan-Kettering Cancer Center | Gene expression profiles associated with metastatic breast cancer |
| US20150299799A1 (en) | 2012-10-05 | 2015-10-22 | Michael Sturzl | Method for Detecting an Increased Risk or Incidence of Colorectal Cancer |
| CA2891653A1 (en) | 2012-11-16 | 2014-05-22 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| KR101672531B1 (ko) * | 2013-04-18 | 2016-11-17 | 주식회사 젠큐릭스 | 조기 유방암 예후 예측 진단용 유전자 마커 및 이의 용도 |
| WO2014194078A1 (en) * | 2013-05-30 | 2014-12-04 | Genomic Health, Inc. | Gene expression profile algorithm for calculating a recurrence score for a patient with kidney cancer |
| US10392667B2 (en) * | 2013-06-07 | 2019-08-27 | Medical Prognosis Institute A/S | Methods and devices for predicting treatment efficacy of fulvestrant in cancer patients |
| US20170073763A1 (en) * | 2014-03-12 | 2017-03-16 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and Compositions for Assessing Patients with Non-small Cell Lung Cancer |
| EP3143160B1 (en) | 2014-05-13 | 2019-11-06 | Myriad Genetics, Inc. | Gene signatures for cancer prognosis |
| DK3198035T3 (da) | 2014-09-26 | 2023-01-30 | Allarity Therapeutics Europe ApS | Fremgangsmåder til forudsigelse af medicinrespons |
| US10184154B2 (en) | 2014-09-26 | 2019-01-22 | Mayo Foundation For Medical Education And Research | Detecting cholangiocarcinoma |
| WO2016092299A1 (en) * | 2014-12-09 | 2016-06-16 | Medical Research Council | Methods and kits for predicting the response to therapy of cancer |
| CN107532124B (zh) | 2015-03-27 | 2022-08-09 | 精密科学公司 | 检测食管疾病 |
| AU2016343937B2 (en) | 2015-10-30 | 2023-01-19 | Exact Sciences Corporation | Multiplex amplification detection assay and isolation and detection of DNA from plasma |
| CA3008273A1 (en) | 2015-12-18 | 2017-06-22 | Clear Gene, Inc. | Methods, compositions, kits and devices for rapid analysis of biological markers |
| US11680298B2 (en) | 2016-09-07 | 2023-06-20 | Agency For Science, Technology And Research | Method of identifying risk of cancer and therapeutic options |
| US9725769B1 (en) | 2016-10-07 | 2017-08-08 | Oncology Venture ApS | Methods for predicting drug responsiveness in cancer patients |
| AU2017258901A1 (en) | 2016-12-30 | 2018-07-19 | Allarity Therapeutics Europe ApS | Methods for predicting drug responsiveness in cancer patients |
| EP3574110A4 (en) | 2017-01-27 | 2021-01-13 | Exact Sciences Development Company, LLC | DETECTION OF COLUMN NEOPLASIA BY ANALYSIS OF METHYLATED DNA |
| WO2018212192A1 (ja) * | 2017-05-18 | 2018-11-22 | 京都府公立大学法人 | 癌の予後及び／又は転移可能性を評価する方法及びマーカー |
| US12275994B2 (en) * | 2017-06-22 | 2025-04-15 | Clear Gene, Inc. | Methods and compositions for the analysis of cancer biomarkers |
| KR102424222B1 (ko) | 2017-11-13 | 2022-07-21 | 더 멀티플 마이얼로머 리서치 파운데이션, 인크. | 통합된, 분자, 체학, 면역요법, 대사, 후성적, 및 임상 데이터베이스 |
| US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
| US11198911B2 (en) * | 2018-03-08 | 2021-12-14 | University Of Notre Dame Du Lac | Systems and methods for assessing colorectal cancer molecular subtype and risk of recurrence and for determining and administering treatment protocols based thereon |
| JP7199045B2 (ja) * | 2018-04-13 | 2023-01-05 | 国立大学法人大阪大学 | 乳癌の予後に関する情報の取得方法、乳癌の予後の判定装置及びコンピュータプログラム |
| JP7444376B2 (ja) * | 2018-09-21 | 2024-03-06 | 国立大学法人 東京大学 | がんの予後判定方法 |
| JP2019032334A (ja) * | 2018-10-03 | 2019-02-28 | イムノヴィア・アクチエボラーグ | 乳癌関連の疾患状態を決定する方法およびこの方法における使用のためのアレイ |
| KR102216645B1 (ko) * | 2018-10-29 | 2021-02-17 | 사회복지법인 삼성생명공익재단 | 폐암의 분자 아형 결정을 위한 바이오마커 패널 및 이의 용도 |
| JP2022512152A (ja) * | 2018-12-08 | 2022-02-02 | ピーエフエス・ジェノミクス・インコーポレイテッド | 乳がんの予後についてのトランスクリプトームプロファイリング |
| JP7584151B2 (ja) * | 2019-05-03 | 2024-11-15 | ディーシージェン カンパニー リミテッド | 癌の予後予測方法およびその組成物 |
| CN111235270B (zh) * | 2019-08-29 | 2022-04-29 | 北京臻知医学科技有限责任公司 | 一种基于高通量测序法的肿瘤抗原表达检测引物及试剂盒 |
| US12165747B2 (en) * | 2020-01-23 | 2024-12-10 | The Broad Institute, Inc. | Molecular spatial mapping of metastatic tumor microenvironment |
| WO2022174089A1 (en) * | 2021-02-12 | 2022-08-18 | Mammogen, Inc. | Biomarkers for the diagnosis of breast cancer |
| WO2022192128A2 (en) * | 2021-03-08 | 2022-09-15 | Castle Biosciences, Inc. | Determining prognosis and treatment based on clinical-pathologic factors and continuous multigene-expression profile scores |
| CN117116345B (zh) * | 2023-07-24 | 2025-09-16 | 中国人民解放军军事科学院军事医学研究院 | 一种基于基因调控网络构建患者生存网络的方法 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7171311B2 (en) * | 2001-06-18 | 2007-01-30 | Rosetta Inpharmatics Llc | Methods of assigning treatment to breast cancer patients |
| US7514209B2 (en) * | 2001-06-18 | 2009-04-07 | Rosetta Inpharmatics Llc | Diagnosis and prognosis of breast cancer patients |
| US7705120B2 (en) * | 2001-06-21 | 2010-04-27 | Millennium Pharmaceuticals, Inc. | Compositions, kits, and methods for identification, assessment, prevention, and therapy of breast cancer |
| ATE529535T1 (de) * | 2002-03-13 | 2011-11-15 | Genomic Health Inc | Genexpressionsprofilierung in einer biopsie unterzogenem tumorgewebe |
| US20040067234A1 (en) * | 2002-07-11 | 2004-04-08 | Paz Einat | Isocitrate dehydrogenase and uses thereof |
| US20040231909A1 (en) * | 2003-01-15 | 2004-11-25 | Tai-Yang Luh | Motorized vehicle having forward and backward differential structure |
| EP3330875B1 (en) * | 2003-07-10 | 2021-12-01 | Genomic Health, Inc. | Expression profile algorithm and test for prognosing breast cancer recurrence |
| JP2007527247A (ja) * | 2004-03-05 | 2007-09-27 | ロゼッタ インファーマティクス エルエルシー | 臨床的基準および情報提供性遺伝子セットの組合せを使用する乳癌患者の分類 |
| US20080299550A1 (en) * | 2004-09-20 | 2008-12-04 | Bayer Healthcare Ag | Methods and Kits For the Prediction of Therapeutic Success and Recurrence Free Survival In Cancer Therapy |
| WO2006103442A2 (en) * | 2005-04-01 | 2006-10-05 | Ncc Technology Ventures Pte. Ltd. | Materials and methods relating to breast cancer classification |
| WO2006133460A2 (en) * | 2005-06-09 | 2006-12-14 | Yale University | Methods for diagnosing and treating breast cancer based on a her/er ratio |
| AU2006259583A1 (en) * | 2005-06-13 | 2006-12-28 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| US20070099209A1 (en) * | 2005-06-13 | 2007-05-03 | The Regents Of The University Of Michigan | Compositions and methods for treating and diagnosing cancer |
| TWI304443B (en) * | 2005-12-30 | 2008-12-21 | Nat Health Research Institutes | Alpha-enolase specific antibody and method of use |
| US7888019B2 (en) * | 2006-03-31 | 2011-02-15 | Genomic Health, Inc. | Genes involved estrogen metabolism |
| EP2140025A2 (en) * | 2007-04-16 | 2010-01-06 | Ipsogen | Methods of assessing a propensity of clinical outcome for a female mammal suffering from breast cancer |
| WO2008150512A2 (en) * | 2007-06-04 | 2008-12-11 | University Of Louisville Research Foundation, Inc. | Methods for identifying an increased likelihood of recurrence of breast cancer |
| WO2009095319A1 (en) * | 2008-01-28 | 2009-08-06 | Siemens Healthcare Diagnostics Gmbh | Cancer prognosis by majority voting |
| WO2009132928A2 (en) * | 2008-05-02 | 2009-11-05 | Siemens Healthcare Diagnostics Gmbh | Molecular markers for cancer prognosis |
| ES2403220T3 (es) * | 2008-05-12 | 2013-05-16 | Genomic Health, Inc. | Pruebas para predecir la receptividad de pacientes con cáncer a opciones de tratamiento con quimioterapia |
| AU2010321829B2 (en) * | 2009-11-23 | 2015-07-30 | Genomic Health, Inc. | Methods to predict clinical outcome of cancer |
-
2010
- 2010-11-19 AU AU2010321829A patent/AU2010321829B2/en active Active
- 2010-11-19 ES ES10832289T patent/ES2735993T3/es active Active
- 2010-11-19 US US12/950,732 patent/US20110123990A1/en not_active Abandoned
- 2010-11-19 MX MX2019003811A patent/MX391499B/es unknown
- 2010-11-19 MX MX2016003089A patent/MX363817B/es unknown
- 2010-11-19 HU HUE10832289 patent/HUE044374T2/hu unknown
- 2010-11-19 CA CA2776751A patent/CA2776751C/en active Active
- 2010-11-19 NZ NZ599194A patent/NZ599194A/en unknown
- 2010-11-19 WO PCT/US2010/057490 patent/WO2011063274A2/en not_active Ceased
- 2010-11-19 PL PL10832289T patent/PL2504451T3/pl unknown
- 2010-11-19 EP EP23213439.5A patent/EP4350001A3/en active Pending
- 2010-11-19 CA CA3043089A patent/CA3043089A1/en not_active Withdrawn
- 2010-11-19 EP EP19175741.8A patent/EP3556867A1/en not_active Withdrawn
- 2010-11-19 EP EP10832289.2A patent/EP2504451B1/en active Active
- 2010-11-19 MX MX2012005822A patent/MX337650B/es active IP Right Grant
- 2010-11-19 JP JP2012540103A patent/JP5964752B2/ja active Active
- 2010-11-19 EP EP20177718.2A patent/EP3739060A1/en not_active Withdrawn
- 2010-11-19 DK DK10832289.2T patent/DK2504451T3/da active
-
2012
- 2012-04-04 IL IL219051A patent/IL219051A/en active IP Right Grant
-
2016
- 2016-06-30 JP JP2016129697A patent/JP2016214245A/ja active Pending
- 2016-11-23 IL IL249159A patent/IL249159A0/en unknown
-
2017
- 2017-02-03 US US15/423,977 patent/US20170211154A1/en not_active Abandoned
-
2018
- 2018-01-21 IL IL257063A patent/IL257063B/en active IP Right Grant
- 2018-08-02 JP JP2018145578A patent/JP7042717B2/ja active Active
-
2019
- 2019-01-03 IL IL264072A patent/IL264072B/en active IP Right Grant
- 2019-01-09 US US16/243,207 patent/US20190241967A1/en not_active Abandoned
-
2020
- 2020-08-04 IL IL276487A patent/IL276487B/en unknown
- 2020-09-11 US US17/018,143 patent/US20210062275A1/en not_active Abandoned
- 2020-12-28 JP JP2020218527A patent/JP2021058207A/ja active Pending
-
2022
- 2022-08-02 JP JP2022123265A patent/JP2022166064A/ja active Pending
- 2022-08-16 JP JP2022129605A patent/JP2022169647A/ja active Pending
-
2023
- 2023-12-18 JP JP2023213416A patent/JP2024037948A/ja active Pending
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