JP2016135784A5 - - Google Patents
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- Publication number
- JP2016135784A5 JP2016135784A5 JP2016012103A JP2016012103A JP2016135784A5 JP 2016135784 A5 JP2016135784 A5 JP 2016135784A5 JP 2016012103 A JP2016012103 A JP 2016012103A JP 2016012103 A JP2016012103 A JP 2016012103A JP 2016135784 A5 JP2016135784 A5 JP 2016135784A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- nucleic acid
- binding
- support
- ligand
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 150000007523 nucleic acids Chemical class 0.000 claims 9
- 102000039446 nucleic acids Human genes 0.000 claims 9
- 108020004707 nucleic acids Proteins 0.000 claims 9
- 238000000034 method Methods 0.000 claims 6
- 239000003446 ligand Substances 0.000 claims 4
- 238000012986 modification Methods 0.000 claims 4
- 230000004048 modification Effects 0.000 claims 4
- BLRPTPMANUNPDV-UHFFFAOYSA-N Silane Chemical compound [SiH4] BLRPTPMANUNPDV-UHFFFAOYSA-N 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 229910000077 silane Inorganic materials 0.000 claims 3
- UNVFWCQQWZUPLB-UHFFFAOYSA-N 3-[dimethoxy(pentan-3-yloxy)silyl]propan-1-amine Chemical compound CCC(CC)O[Si](OC)(OC)CCCN UNVFWCQQWZUPLB-UHFFFAOYSA-N 0.000 claims 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims 2
- 238000010828 elution Methods 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- JKNCOURZONDCGV-UHFFFAOYSA-N 2-(dimethylamino)ethyl 2-methylprop-2-enoate Chemical compound CN(C)CCOC(=O)C(C)=C JKNCOURZONDCGV-UHFFFAOYSA-N 0.000 claims 1
- WIYVVIUBKNTNKG-UHFFFAOYSA-N 6,7-dimethoxy-3,4-dihydronaphthalene-2-carboxylic acid Chemical compound C1CC(C(O)=O)=CC2=C1C=C(OC)C(OC)=C2 WIYVVIUBKNTNKG-UHFFFAOYSA-N 0.000 claims 1
- 150000001252 acrylic acid derivatives Chemical class 0.000 claims 1
- 125000003277 amino group Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 150000004756 silanes Chemical class 0.000 claims 1
- 239000000377 silicon dioxide Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102008063001.2 | 2008-12-23 | ||
| DE102008063001A DE102008063001A1 (de) | 2008-12-23 | 2008-12-23 | Nukleinsäureaufreinigungsverfahren |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011541520A Division JP2012513386A (ja) | 2008-12-23 | 2009-12-23 | 核酸の精製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016135784A JP2016135784A (ja) | 2016-07-28 |
| JP2016135784A5 true JP2016135784A5 (OSRAM) | 2016-09-29 |
| JP6072945B2 JP6072945B2 (ja) | 2017-02-01 |
Family
ID=42078045
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011541520A Withdrawn JP2012513386A (ja) | 2008-12-23 | 2009-12-23 | 核酸の精製方法 |
| JP2016012103A Active JP6072945B2 (ja) | 2008-12-23 | 2016-01-26 | 核酸の精製方法 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011541520A Withdrawn JP2012513386A (ja) | 2008-12-23 | 2009-12-23 | 核酸の精製方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9102935B2 (OSRAM) |
| EP (1) | EP2382315B1 (OSRAM) |
| JP (2) | JP2012513386A (OSRAM) |
| CN (1) | CN102264902B (OSRAM) |
| AU (1) | AU2009332900B2 (OSRAM) |
| DE (1) | DE102008063001A1 (OSRAM) |
| WO (1) | WO2010072834A1 (OSRAM) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102008063003A1 (de) * | 2008-12-23 | 2010-06-24 | Qiagen Gmbh | Nukleinsäureaufreinigungsverfahren |
| JP5899731B2 (ja) * | 2011-09-13 | 2016-04-06 | ソニー株式会社 | 核酸精製方法、核酸抽出方法、及び核酸精製用キット |
| EP2760999A1 (en) | 2011-09-26 | 2014-08-06 | Qiagen GmbH | Methods for separating nucleic acids by size |
| EP2761001B1 (en) * | 2011-09-26 | 2018-08-01 | Qiagen GmbH | Rapid method for isolating extracellular nucleic acids |
| US9340828B2 (en) | 2011-10-27 | 2016-05-17 | Ge Healthcare Bio-Sciences Ab | Purification of nucleic acid |
| JP6363593B2 (ja) * | 2012-05-31 | 2018-07-25 | エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ | 負に帯電した粒子を用いたクロマトグラフィによるポリヌクレオチドの精製 |
| CN103789297A (zh) * | 2012-10-26 | 2014-05-14 | 上海医脉赛科技有限公司 | 快速纯化核酸的方法及试剂盒 |
| US9938520B2 (en) | 2012-12-11 | 2018-04-10 | Qiagen Gmbh | Preparation of silica particles |
| US10077439B2 (en) | 2013-03-15 | 2018-09-18 | Modernatx, Inc. | Removal of DNA fragments in mRNA production process |
| US10138507B2 (en) | 2013-03-15 | 2018-11-27 | Modernatx, Inc. | Manufacturing methods for production of RNA transcripts |
| WO2014144767A1 (en) * | 2013-03-15 | 2014-09-18 | Moderna Therapeutics, Inc. | Ion exchange purification of mrna |
| EP3191590B1 (en) * | 2014-09-10 | 2024-02-21 | Quantumdx Group Limited | Sorbent material for separating bio-macromolecules |
| JP2017539080A (ja) | 2014-10-23 | 2017-12-28 | コーニング インコーポレイテッド | 高分子被包磁性ナノ粒子 |
| EP3272866B1 (en) * | 2015-03-20 | 2021-11-03 | Toray Industries, Inc. | Method for collecting nucleic acid |
| EP3885438A1 (en) | 2015-06-10 | 2021-09-29 | QIAGEN GmbH | Method for isolating extracellular nucleic acids using anion exchange particles |
| JP7163186B2 (ja) | 2016-03-19 | 2022-10-31 | キアゲン ゲーエムベーハー | Ｒｎａの安定化 |
| US12385034B2 (en) | 2016-06-24 | 2025-08-12 | Modernatx, Inc. | Methods and apparatus for filtration |
| WO2019131760A1 (ja) * | 2017-12-27 | 2019-07-04 | 東レ株式会社 | 核酸の回収方法 |
| CN108102881A (zh) * | 2018-02-05 | 2018-06-01 | 中国科学院苏州纳米技术与纳米仿生研究所 | 具有微结构阵列的微流控芯片及核酸固相纯化提取方法 |
| CN108795929A (zh) * | 2018-07-06 | 2018-11-13 | 大连元和健路医学检验实验室有限公司 | 一种dna分子筛柱子的制备方法 |
| CN108456678A (zh) * | 2018-07-06 | 2018-08-28 | 大连元和健路医学检验实验室有限公司 | 一种快速提取基因组dna的方法 |
| JP7368455B2 (ja) * | 2019-03-29 | 2023-10-24 | 住友化学株式会社 | 無機多孔質担体、及びこれを用いた核酸の製造方法 |
| WO2021122846A1 (en) | 2019-12-16 | 2021-06-24 | Qiagen Gmbh | Enrichment method |
| WO2022263500A1 (en) | 2021-06-17 | 2022-12-22 | Qiagen Gmbh | Method for isolating non-vesicular mirna |
| WO2023084369A1 (en) | 2021-11-12 | 2023-05-19 | 3M Innovative Properties Company | Method of processing polynucleic acids |
| CN115537416A (zh) * | 2022-09-29 | 2022-12-30 | 杭州联川生物技术股份有限公司 | 一种纯化寡核苷酸的方法和试剂盒 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4767670A (en) * | 1987-01-21 | 1988-08-30 | E. I. Du Pont De Nemours And Company | Chromatographic supports for separation of oligonucleotides |
| US5079600A (en) * | 1987-03-06 | 1992-01-07 | Schnur Joel M | High resolution patterning on solid substrates |
| JPH10502052A (ja) * | 1994-04-08 | 1998-02-24 | ハイブライドン インコーポレイテッド | 陰イオン交換クロマトグラフィーを用いるオリゴデオキシヌクレオチド・ホスホロチエオエートの精製 |
| US5582988A (en) | 1994-09-15 | 1996-12-10 | Johnson & Johnson Clinical Diagnostics, Inc. | Methods for capture and selective release of nucleic acids using weakly basic polymer and amplification of same |
| US5652348A (en) * | 1994-09-23 | 1997-07-29 | Massey University | Chromatographic resins and methods for using same |
| JP3689896B2 (ja) * | 1995-12-04 | 2005-08-31 | Ｊｓｒ株式会社 | 核酸吸着剤 |
| US6103479A (en) * | 1996-05-30 | 2000-08-15 | Cellomics, Inc. | Miniaturized cell array methods and apparatus for cell-based screening |
| DK1036082T3 (da) | 1997-12-06 | 2002-08-12 | Dna Res Innovations Ltd | Isolering af nucleinsyrer |
| US6914137B2 (en) * | 1997-12-06 | 2005-07-05 | Dna Research Innovations Limited | Isolation of nucleic acids |
| US6310199B1 (en) * | 1999-05-14 | 2001-10-30 | Promega Corporation | pH dependent ion exchange matrix and method of use in the isolation of nucleic acids |
| JP2003104996A (ja) * | 2001-09-28 | 2003-04-09 | Hitachi Maxell Ltd | 核酸結合用磁性担体およびその製造方法 |
| KR100714988B1 (ko) * | 2005-08-09 | 2007-05-09 | 삼성전자주식회사 | 산화막이 표면에 형성된 실리콘 구조물 표면을 이용한ｄｎａ 정제 방법 및 정제장치 |
| WO2008097342A2 (en) | 2006-07-31 | 2008-08-14 | Sigma-Aldrich Co. | Compositions and methods for isolation of biological molecules |
| WO2008035991A2 (en) * | 2006-09-19 | 2008-03-27 | Michael Ronald Cook | A nucleic acid extraction method |
-
2008
- 2008-12-23 DE DE102008063001A patent/DE102008063001A1/de not_active Withdrawn
-
2009
- 2009-12-23 CN CN200980152958.XA patent/CN102264902B/zh active Active
- 2009-12-23 JP JP2011541520A patent/JP2012513386A/ja not_active Withdrawn
- 2009-12-23 EP EP09804132.0A patent/EP2382315B1/de active Active
- 2009-12-23 AU AU2009332900A patent/AU2009332900B2/en active Active
- 2009-12-23 WO PCT/EP2009/067909 patent/WO2010072834A1/de not_active Ceased
- 2009-12-23 US US13/141,878 patent/US9102935B2/en active Active
-
2016
- 2016-01-26 JP JP2016012103A patent/JP6072945B2/ja active Active
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