JP2016044170A5 - - Google Patents
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- Publication number
- JP2016044170A5 JP2016044170A5 JP2014172328A JP2014172328A JP2016044170A5 JP 2016044170 A5 JP2016044170 A5 JP 2016044170A5 JP 2014172328 A JP2014172328 A JP 2014172328A JP 2014172328 A JP2014172328 A JP 2014172328A JP 2016044170 A5 JP2016044170 A5 JP 2016044170A5
- Authority
- JP
- Japan
- Prior art keywords
- stearic acid
- excipient
- olmesartan medoxomil
- granulated product
- particle size
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- QIQXTHQIDYTFRH-UHFFFAOYSA-N Stearic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims 14
- UQGKUQLKSCSZGY-UHFFFAOYSA-N (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate Chemical compound C=1C=C(C=2C(=CC=CC=2)C2=NNN=N2)C=CC=1CN1C(CCC)=NC(C(C)(C)O)=C1C(=O)OCC=1OC(=O)OC=1C UQGKUQLKSCSZGY-UHFFFAOYSA-N 0.000 claims 7
- 239000002051 C09CA08 - Olmesartan medoxomil Substances 0.000 claims 7
- 229960001199 Olmesartan medoxomil Drugs 0.000 claims 7
- 235000021355 Stearic acid Nutrition 0.000 claims 7
- 239000008117 stearic acid Substances 0.000 claims 7
- 239000002245 particle Substances 0.000 claims 4
- 239000011230 binding agent Substances 0.000 claims 3
- 239000007884 disintegrant Substances 0.000 claims 3
- 239000000314 lubricant Substances 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 229920002261 Corn starch Polymers 0.000 claims 1
- FBPFZTCFMRRESA-KAZBKCHUSA-N D-Mannitol Natural products OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KAZBKCHUSA-N 0.000 claims 1
- GUBGYTABKSRVRQ-UUNJERMWSA-N Lactose Natural products O([C@@H]1[C@H](O)[C@H](O)[C@H](O)O[C@@H]1CO)[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1 GUBGYTABKSRVRQ-UUNJERMWSA-N 0.000 claims 1
- FBPFZTCFMRRESA-KVTDHHQDSA-N Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
- 239000001913 cellulose Substances 0.000 claims 1
- 229920002678 cellulose Polymers 0.000 claims 1
- 239000008120 corn starch Substances 0.000 claims 1
- 239000008187 granular material Substances 0.000 claims 1
- 239000008101 lactose Substances 0.000 claims 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N lactose group Chemical group OC1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)[C@H](O1)CO GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 claims 1
- 235000010355 mannitol Nutrition 0.000 claims 1
- 229920001592 potato starch Polymers 0.000 claims 1
- 238000005550 wet granulation Methods 0.000 claims 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014172328A JP6653116B2 (ja) | 2014-08-27 | 2014-08-27 | オルメサルタンのプロドラッグ製剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014172328A JP6653116B2 (ja) | 2014-08-27 | 2014-08-27 | オルメサルタンのプロドラッグ製剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2019089234A Division JP6765473B2 (ja) | 2019-05-09 | 2019-05-09 | オルメサルタンのプロドラッグ製剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016044170A JP2016044170A (ja) | 2016-04-04 |
| JP2016044170A5 true JP2016044170A5 (ru) | 2017-08-24 |
| JP6653116B2 JP6653116B2 (ja) | 2020-02-26 |
Family
ID=55635052
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014172328A Active JP6653116B2 (ja) | 2014-08-27 | 2014-08-27 | オルメサルタンのプロドラッグ製剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6653116B2 (ru) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2750956T3 (es) | 2014-02-13 | 2020-03-30 | Incyte Corp | Ciclopropilaminas como inhibidores de LSD1 |
| SG11201606689VA (en) | 2014-02-13 | 2016-09-29 | Incyte Corp | Cyclopropylamines as lsd1 inhibitors |
| US9695167B2 (en) | 2014-07-10 | 2017-07-04 | Incyte Corporation | Substituted triazolo[1,5-a]pyridines and triazolo[1,5-a]pyrazines as LSD1 inhibitors |
| NZ735998A (en) | 2015-04-03 | 2024-08-30 | Incyte Holdings Corp | Heterocyclic compounds as lsd1 inhibitors |
| NZ740186A (en) | 2015-08-12 | 2024-07-05 | Incyte Holdings Corp | Salts of an lsd1 inhibitor |
| US10968200B2 (en) | 2018-08-31 | 2021-04-06 | Incyte Corporation | Salts of an LSD1 inhibitor and processes for preparing the same |
| CA3164198A1 (en) * | 2020-01-16 | 2021-07-22 | Eisai R&D Management Co., Ltd. | Drug substance of lemborexant and medicinal composition comprising same |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006123765A1 (ja) * | 2005-05-20 | 2006-11-23 | Daiichi Sankyo Company, Limited | フィルムコーティング製剤 |
| US20070105923A1 (en) * | 2005-09-14 | 2007-05-10 | Glenmark Pharmaceuticals Limited | Substantially pure olmesartan medoxomil and processes for its preparation |
| ATE526963T1 (de) * | 2006-05-04 | 2011-10-15 | Lek Pharmaceuticals | Pharmazeutische zusammensetzung mit olmesartan- medoxomil |
| JPWO2008117707A1 (ja) * | 2007-03-23 | 2010-07-15 | 第一三共株式会社 | オルメサルタンメドキソミルの粉砕結晶 |
| WO2010018777A1 (ja) * | 2008-08-11 | 2010-02-18 | 第一三共株式会社 | におい抑制方法 |
| US20110256221A1 (en) * | 2008-12-30 | 2011-10-20 | Farhad Farshi | Pharmaceutical formulations of olmesartan |
| HUP0900384A2 (en) * | 2009-06-19 | 2011-01-28 | Nangenex Nanotechnologiai Zartkoerueen Muekoedoe Reszvenytarsasag | Nanoparticulate olmesartan medoxomil compositions |
| WO2011045760A2 (en) * | 2009-10-13 | 2011-04-21 | Ranbaxy Laboratories Limited | Micronized olmesartan medoxomil compositions |
| JP5680898B2 (ja) * | 2010-08-10 | 2015-03-04 | 京都薬品工業株式会社 | 苦味を抑制した速崩壊錠 |
| WO2014080365A1 (en) * | 2012-11-23 | 2014-05-30 | Ranbaxy Laboratories Limited | Method of reducing an unpleasant odor of a pharmaceutical composition |
-
2014
- 2014-08-27 JP JP2014172328A patent/JP6653116B2/ja active Active
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