JP2016014025A5 - - Google Patents

Info

Publication number

JP2016014025A5

JP2016014025A5 JP2015141987A JP2015141987A JP2016014025A5 JP 2016014025 A5 JP2016014025 A5 JP 2016014025A5 JP 2015141987 A JP2015141987 A JP 2015141987A JP 2015141987 A JP2015141987 A JP 2015141987A JP 2016014025 A5 JP2016014025 A5 JP 2016014025A5

Authority

JP

Japan

Prior art keywords

hydrogel

conjugate

solution

flavonoid

forming substance

Prior art date

2015-07-16

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
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• 238000000034 method Methods 0.000 claims 16
• 229930003935 flavonoid Natural products 0.000 claims 7
• 235000017173 flavonoids Nutrition 0.000 claims 7
• 239000000126 substance Substances 0.000 claims 7
• 150000002215 flavonoids Chemical class 0.000 claims 6
• 239000000017 hydrogel Substances 0.000 claims 6
• 102000003992 Peroxidases Human genes 0.000 claims 2
• 239000002246 antineoplastic agent Substances 0.000 claims 2
• 230000000975 bioactive effect Effects 0.000 claims 2
• 238000001879 gelation Methods 0.000 claims 2
• 238000004519 manufacturing process Methods 0.000 claims 2
• 108040007629 peroxidase activity proteins Proteins 0.000 claims 2
• 150000002978 peroxides Chemical class 0.000 claims 2
• WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 claims 1
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical group CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 1
• 102000016938 Catalase Human genes 0.000 claims 1
• 108010053835 Catalase Proteins 0.000 claims 1
• WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 claims 1
• -1 catechin skeleton flavonoid Chemical class 0.000 claims 1
• 229940030275 epigallocatechin gallate Drugs 0.000 claims 1
• 229940022353 herceptin Drugs 0.000 claims 1
• 229920002674 hyaluronan Polymers 0.000 claims 1
• 229960003160 hyaluronic acid Drugs 0.000 claims 1
• 229920000642 polymer Polymers 0.000 claims 1