SG176286A1 - Flavonoid hydrogel - Google Patents
Flavonoid hydrogel Download PDFInfo
- Publication number
- SG176286A1 SG176286A1 SG2011088283A SG2011088283A SG176286A1 SG 176286 A1 SG176286 A1 SG 176286A1 SG 2011088283 A SG2011088283 A SG 2011088283A SG 2011088283 A SG2011088283 A SG 2011088283A SG 176286 A1 SG176286 A1 SG 176286A1
- Authority
- SG
- Singapore
- Prior art keywords
- hydrogel
- flavonoid
- cell
- conjugates
- cells
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/01—Hydrocarbons
- A61K31/015—Hydrocarbons carbocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/738—Cross-linked polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6903—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being semi-solid, e.g. an ointment, a gel, a hydrogel or a solidifying gel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/02—Oxygen as only ring hetero atoms
- C12P17/06—Oxygen as only ring hetero atoms containing a six-membered hetero ring, e.g. fluorescein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2397/00—Characterised by the use of lignin-containing materials
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Polymers & Plastics (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Transplantation (AREA)
- Neurosurgery (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Virology (AREA)
- Cardiology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21333109P | 2009-05-29 | 2009-05-29 | |
| PCT/SG2010/000185 WO2010138082A1 (en) | 2009-05-29 | 2010-05-17 | Flavonoid hydrogel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG176286A1 true SG176286A1 (en) | 2012-01-30 |
Family
ID=43222961
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG2011088283A SG176286A1 (en) | 2009-05-29 | 2010-05-17 | Flavonoid hydrogel |
| SG10201402723QA SG10201402723QA (en) | 2009-05-29 | 2010-05-17 | Flavonoid hydrogel |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG10201402723QA SG10201402723QA (en) | 2009-05-29 | 2010-05-17 | Flavonoid hydrogel |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US8541016B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2435504B1 (cg-RX-API-DMAC7.html) |
| JP (2) | JP5843758B2 (cg-RX-API-DMAC7.html) |
| SG (2) | SG176286A1 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2010138082A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101694920B1 (ko) * | 2007-10-23 | 2017-01-11 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 세포에 항암제를 전달하는 방법 |
| US8734867B2 (en) | 2007-12-28 | 2014-05-27 | Liveleaf, Inc. | Antibacterial having an extract of pomegranate combined with hydrogen peroxide |
| WO2010138082A1 (en) | 2009-05-29 | 2010-12-02 | Agency For Science, Technology And Research | Flavonoid hydrogel |
| SG184027A1 (en) * | 2010-03-11 | 2012-10-30 | Agency Science Tech & Res | Anti-cancer agent delivery vehicles capable of improved laoding |
| US8722040B2 (en) * | 2011-06-24 | 2014-05-13 | Liveleaf, Inc. | Site-activated binding systems that selectively increase the bioactivity of phenolic compounds at target sites |
| US9192635B2 (en) | 2011-06-24 | 2015-11-24 | Liveleaf, Inc. | Method of treating damaged mucosal or gastrointestinal tissue by administering a composition comprising a mixture of pomegranate and green tea extracts and releasably bound hydrogen peroxide |
| US8716351B1 (en) | 2012-12-23 | 2014-05-06 | Liveleaf, Inc. | Methods of treating gastrointestinal spasms |
| CN105452450B (zh) * | 2013-06-18 | 2020-07-07 | 新加坡科技研究局 | 培养癌干细胞的方法 |
| SG11201601612UA (en) * | 2013-09-03 | 2016-04-28 | Agency Science Tech & Res | Polymer-flavonoid conjugates and hydrogels for biomedical applications |
| GB2518405A (en) * | 2013-09-20 | 2015-03-25 | Zeiss Carl Meditec Ag | Composition comprising at least one viscoelastic polymer |
| WO2015070100A1 (en) | 2013-11-08 | 2015-05-14 | The Johns Hopkins University | Oxygen-controllable and hypoxia-inducible hydrogels |
| US10004586B2 (en) | 2014-08-27 | 2018-06-26 | The Cleveland Clinic Foundation | Biocompatible tissue graft |
| EP3782613B1 (en) * | 2018-04-02 | 2023-12-06 | Optipharm Co., Ltd | Alginate microcapsules for cell encapsulation and, manufacturing method therefor |
| KR102326127B1 (ko) * | 2019-06-27 | 2021-11-12 | 서울대학교산학협력단 | 녹차 유래 폴리페놀을 이용한 주입형 조직 접착 하이드로젤, 그의 제조 방법 및 그의 응용 |
| US12478578B2 (en) * | 2019-12-03 | 2025-11-25 | Massachusetts Eye And Ear Infirmary | Injectable hydrogels for cell delivery to the vitreous |
| CN113892643A (zh) * | 2021-09-23 | 2022-01-07 | 西北农林科技大学 | 一种用于细胞培养肉的可食用的采用茶多酚涂层的海藻酸钠/明胶3d凝胶支架的制造方法 |
| CN114736254B (zh) * | 2022-03-30 | 2024-01-05 | 湖南大学 | 一种天然黄酮类化合物衍生物药物及其制备方法和应用 |
| CN117046406A (zh) * | 2023-08-15 | 2023-11-14 | 中国人民解放军军事科学院军事医学研究院 | 基于天然产物儿茶素的自组装水凝胶及制备方法与应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6630457B1 (en) | 1998-09-18 | 2003-10-07 | Orthogene Llc | Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same |
| US6982298B2 (en) * | 2003-01-10 | 2006-01-03 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
| US7858080B2 (en) | 2005-05-20 | 2010-12-28 | Agency For Science, Technology And Research | Aldehyde conjugated flavonoid preparations |
| CN101180319B (zh) | 2005-05-20 | 2012-06-27 | 新加坡科技研究局 | 醛结合的类黄酮制剂 |
| JP4712505B2 (ja) * | 2005-09-30 | 2011-06-29 | 富士フイルム株式会社 | 電子内視鏡装置 |
| JP2009528080A (ja) | 2006-02-27 | 2009-08-06 | エイジェンシー・フォー・サイエンス,テクノロジー・アンド・リサーチ | 硬化性骨セメント |
| JP2007297360A (ja) * | 2006-05-08 | 2007-11-15 | Ihara Suisan Kk | ハイドロゲル、その製造方法およびその用途 |
| JP4308230B2 (ja) * | 2006-07-21 | 2009-08-05 | 花王株式会社 | カテキン類の着色抑制方法 |
| EP2045248B1 (en) * | 2006-07-21 | 2013-09-25 | Kao Corporation | Method for preventing coloration of catechins and dentifrice composition |
| KR100968591B1 (ko) * | 2007-06-14 | 2010-07-08 | 한국과학기술연구원 | 약물전달용 폴리포스파젠계 하이드로젤, 그의 제조방법 및그의 용도 |
| KR101694920B1 (ko) | 2007-10-23 | 2017-01-11 | 에이전시 포 사이언스, 테크놀로지 앤드 리서치 | 세포에 항암제를 전달하는 방법 |
| US8287906B2 (en) | 2008-05-06 | 2012-10-16 | Agency For Science, Technology And Research | Formation of hydrogel in the presence of peroxidase and low concentration of hydrogen peroxide |
| WO2009148405A1 (en) | 2008-06-05 | 2009-12-10 | Agency For Science, Technology And Research | Formation of hydrogel in the presence of peroxidase and low concentration of hydrogen peroxide |
| WO2010138082A1 (en) | 2009-05-29 | 2010-12-02 | Agency For Science, Technology And Research | Flavonoid hydrogel |
| SG184027A1 (en) | 2010-03-11 | 2012-10-30 | Agency Science Tech & Res | Anti-cancer agent delivery vehicles capable of improved laoding |
-
2010
- 2010-05-17 WO PCT/SG2010/000185 patent/WO2010138082A1/en not_active Ceased
- 2010-05-17 EP EP10780897.4A patent/EP2435504B1/en active Active
- 2010-05-17 SG SG2011088283A patent/SG176286A1/en unknown
- 2010-05-17 JP JP2012513017A patent/JP5843758B2/ja not_active Expired - Fee Related
- 2010-05-17 SG SG10201402723QA patent/SG10201402723QA/en unknown
- 2010-05-17 US US13/375,097 patent/US8541016B2/en not_active Expired - Fee Related
-
2013
- 2013-08-19 US US13/970,432 patent/US9034364B2/en not_active Expired - Fee Related
-
2015
- 2015-04-27 US US14/697,565 patent/US9439886B2/en not_active Expired - Fee Related
- 2015-07-16 JP JP2015141987A patent/JP6112576B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2012528150A (ja) | 2012-11-12 |
| US20150313869A1 (en) | 2015-11-05 |
| WO2010138082A1 (en) | 2010-12-02 |
| JP5843758B2 (ja) | 2016-01-13 |
| US8541016B2 (en) | 2013-09-24 |
| EP2435504B1 (en) | 2020-03-11 |
| JP6112576B2 (ja) | 2017-04-12 |
| EP2435504A4 (en) | 2015-12-02 |
| US9439886B2 (en) | 2016-09-13 |
| SG10201402723QA (en) | 2014-10-30 |
| US20120070433A1 (en) | 2012-03-22 |
| US9034364B2 (en) | 2015-05-19 |
| JP2016014025A (ja) | 2016-01-28 |
| US20130338101A1 (en) | 2013-12-19 |
| EP2435504A1 (en) | 2012-04-04 |
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