BR112015028752A2 - micro- ou nanopartículas antimicrobianas compreendendo um sal de clorexidina, método de produção e usos das mesmas - Google Patents

micro- ou nanopartículas antimicrobianas compreendendo um sal de clorexidina, método de produção e usos das mesmas

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Publication number
BR112015028752A2
BR112015028752A2 BR112015028752-2A BR112015028752A BR112015028752A2 BR 112015028752 A2 BR112015028752 A2 BR 112015028752A2 BR 112015028752 A BR112015028752 A BR 112015028752A BR 112015028752 A2 BR112015028752 A2 BR 112015028752A2
Authority
BR
Brazil
Prior art keywords
nanoparticles
production
chlorhexidine salt
antimicrobial micro
antimicrobial
Prior art date
Application number
BR112015028752-2A
Other languages
English (en)
Inventor
Emily Redmond Michele
Original Assignee
The University Of Bristol
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of Bristol filed Critical The University Of Bristol
Publication of BR112015028752A2 publication Critical patent/BR112015028752A2/pt

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
    • A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
    • A01N47/44—Guanidine; Derivatives thereof
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    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
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    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/12—Powders or granules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/22—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing ingredients stabilising the active ingredients
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
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    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
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    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
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    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
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    • C—CHEMISTRY; METALLURGY
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    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
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    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
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Abstract

resumo da patente de invenção para: “micro- ou nanopartículas antimicrobianas compreendendo um sal de clorexidina, método de produção e usos das mesmas”. micro- ou nanopartículas antimicrobianas compreendendo um sal de clorexidina e um ânion, e um método para produzir a micro- ou nanopartícula antimicrobiana são descritos. o ânion no sal é selecionado a partir de oxoânions e oxoânions parcialmente hidrogenados de fósforo, carbono, nitrogênio e enxofre.
BR112015028752-2A 2013-05-17 2014-05-16 micro- ou nanopartículas antimicrobianas compreendendo um sal de clorexidina, método de produção e usos das mesmas BR112015028752A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1308926.3 2013-05-17
GBGB1308926.3A GB201308926D0 (en) 2013-05-17 2013-05-17 Antibacterial micro-and nanoparticles comprising a chlorhexidine salt, method of production and uses thereof
PCT/GB2014/051515 WO2014184582A1 (en) 2013-05-17 2014-05-16 Antibacterial micro- and nanoparticles comprising a chlorhexidine salt, method of production and uses thereof

Publications (1)

Publication Number Publication Date
BR112015028752A2 true BR112015028752A2 (pt) 2018-01-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015028752-2A BR112015028752A2 (pt) 2013-05-17 2014-05-16 micro- ou nanopartículas antimicrobianas compreendendo um sal de clorexidina, método de produção e usos das mesmas

Country Status (10)

Country Link
US (1) US9717248B2 (pt)
EP (1) EP2996468B1 (pt)
JP (2) JP6506258B2 (pt)
CN (1) CN105228447B (pt)
BR (1) BR112015028752A2 (pt)
CA (1) CA2947930C (pt)
DK (1) DK2996468T3 (pt)
ES (1) ES2732599T3 (pt)
GB (2) GB201308926D0 (pt)
WO (1) WO2014184582A1 (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201604639D0 (en) 2016-03-18 2016-05-04 Univ London Queen Mary Chlorhexidine crystal forms and uses thereof in medicine
US20190117569A1 (en) * 2017-10-24 2019-04-25 Saint Anthony Biomedical, LLC Compositions and methods for reducing infection in wounds and surgical sites
BR112021024074A2 (pt) * 2019-05-31 2022-02-08 Sumitomo Chemical Co Formulação de concentrado de suspensão líquida compreendendo mefentrifluconazol
EP4079340A1 (en) * 2021-04-20 2022-10-26 Mölnlycke Health Care AB A dressing comprising an antimicrobial coating

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59227824A (ja) * 1983-06-10 1984-12-21 Unitika Ltd 抗菌性ラテツクス組成物
US4980150A (en) * 1989-04-27 1990-12-25 Zetachron, Inc. Chlorhexidine complex
US7820734B2 (en) * 1998-10-07 2010-10-26 Tyco Healthcare Group Lp Antimicrobial lubricious coating
FR2792532B1 (fr) * 1999-04-26 2001-12-21 Menarini France Lab Nouvelles compositions antiseptiques et leur procede d'obtention
JP2003089606A (ja) * 2001-07-12 2003-03-28 Kanae Toryo Kk ヒノキチオール徐放剤
US20070212419A1 (en) 2006-02-18 2007-09-13 Jozsef Bako Synthesis of biocompatible nanocomposite hydrogels as a local drug delivery system
JP2010516719A (ja) * 2007-01-23 2010-05-20 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング 抗菌性組成物
BRPI0802906A2 (pt) * 2008-06-27 2011-03-22 Comunidade Evangelica Luterana Sao Paulo Celsp Universidade Luterana Do Brasil Ulbra dentifrìcio não iÈnico e processo de produção do mesmo
AU2010274000A1 (en) 2009-07-17 2012-02-02 Carefusion 2200, Inc. Particles incorporating antimicrobial agents
US20110293690A1 (en) * 2010-05-27 2011-12-01 Tyco Healthcare Group Lp Biodegradable Polymer Encapsulated Microsphere Particulate Film and Method of Making Thereof
US20120150131A1 (en) 2010-12-09 2012-06-14 Teleflex Medical Incorporated Polymer for Controlling Delivery of Bioactive Agents and Method of Use
WO2012119155A1 (en) * 2011-03-03 2012-09-07 American Dental Association Foundation Antimicrobial compositions for tooth fluoridation and remineralization
JP5745303B2 (ja) * 2011-03-29 2015-07-08 株式会社シナネンゼオミック 抗微生物用水処理剤および水処理方法

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GB2516537A (en) 2015-01-28
EP2996468A1 (en) 2016-03-23
JP2019073536A (ja) 2019-05-16
JP6506258B2 (ja) 2019-04-24
CA2947930C (en) 2021-07-13
CA2947930A1 (en) 2014-11-20
JP2016521681A (ja) 2016-07-25
US9717248B2 (en) 2017-08-01
CN105228447A (zh) 2016-01-06
GB201308926D0 (en) 2013-07-03
US20160128332A1 (en) 2016-05-12
GB2516537B (en) 2015-11-25
EP2996468B1 (en) 2019-04-10
GB201408748D0 (en) 2014-07-02
DK2996468T3 (da) 2019-07-01
CN105228447B (zh) 2018-07-20

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