JP2015536312A5 - - Google Patents

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Publication number
JP2015536312A5
JP2015536312A5 JP2015537216A JP2015537216A JP2015536312A5 JP 2015536312 A5 JP2015536312 A5 JP 2015536312A5 JP 2015537216 A JP2015537216 A JP 2015537216A JP 2015537216 A JP2015537216 A JP 2015537216A JP 2015536312 A5 JP2015536312 A5 JP 2015536312A5
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JP
Japan
Prior art keywords
seq
protein
serotype
saccharide
conjugated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2015537216A
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English (en)
Japanese (ja)
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JP6236086B2 (ja
JP2015536312A (ja
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Publication date
Priority claimed from GBGB1218660.7A external-priority patent/GB201218660D0/en
Priority claimed from US13/827,203 external-priority patent/US20140105927A1/en
Priority claimed from US13/826,932 external-priority patent/US20140193451A1/en
Application filed filed Critical
Priority claimed from PCT/EP2013/071472 external-priority patent/WO2014060383A1/en
Publication of JP2015536312A publication Critical patent/JP2015536312A/ja
Publication of JP2015536312A5 publication Critical patent/JP2015536312A5/ja
Application granted granted Critical
Publication of JP6236086B2 publication Critical patent/JP6236086B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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JP2015537216A 2012-10-17 2013-10-15 1種以上の肺炎球菌莢膜糖類コンジュゲートとインフルエンザ菌由来のタンパク質Eおよび/またはPilAを含むタンパク質成分とを含む免疫原性組成物 Active JP6236086B2 (ja)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
US201261714942P 2012-10-17 2012-10-17
US201261714956P 2012-10-17 2012-10-17
US61/714,956 2012-10-17
US61/714,942 2012-10-17
GBGB1218660.7A GB201218660D0 (en) 2012-10-17 2012-10-17 Immunogenic composition
GB1218660.7 2012-10-17
US13/827,203 US20140105927A1 (en) 2012-10-17 2013-03-14 Immunogenic composition
US13/826,696 US9561268B2 (en) 2012-10-17 2013-03-14 Immunogenic composition
US13/826,932 US20140193451A1 (en) 2012-10-17 2013-03-14 Immunogenic composition
US13/827,203 2013-03-14
US13/826,932 2013-03-14
US13/826,696 2013-03-14
PCT/EP2013/071472 WO2014060383A1 (en) 2012-10-17 2013-10-15 Immunogenic composition comprising 1 or more streptococcus pneumoniae capsular saccharide conjugates and a protein component comprising protein e and/or pila fromhaemophilus influenzae.

Publications (3)

Publication Number Publication Date
JP2015536312A JP2015536312A (ja) 2015-12-21
JP2015536312A5 true JP2015536312A5 (enExample) 2016-11-10
JP6236086B2 JP6236086B2 (ja) 2017-11-22

Family

ID=53008966

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2015537216A Active JP6236086B2 (ja) 2012-10-17 2013-10-15 1種以上の肺炎球菌莢膜糖類コンジュゲートとインフルエンザ菌由来のタンパク質Eおよび/またはPilAを含むタンパク質成分とを含む免疫原性組成物
JP2015537220A Pending JP2015534964A (ja) 2012-10-17 2013-10-15 免疫原性組成物
JP2015537218A Expired - Fee Related JP6412500B2 (ja) 2012-10-17 2013-10-15 免疫原性組成物

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2015537220A Pending JP2015534964A (ja) 2012-10-17 2013-10-15 免疫原性組成物
JP2015537218A Expired - Fee Related JP6412500B2 (ja) 2012-10-17 2013-10-15 免疫原性組成物

Country Status (13)

Country Link
EP (3) EP2908855B1 (enExample)
JP (3) JP6236086B2 (enExample)
KR (2) KR20150058571A (enExample)
CN (2) CN104853768B (enExample)
AU (2) AU2013331781A1 (enExample)
BR (3) BR112015008418A2 (enExample)
CA (3) CA2888310C (enExample)
EA (2) EA201590491A1 (enExample)
ES (1) ES2640320T3 (enExample)
IL (2) IL238053A0 (enExample)
MX (2) MX2015005002A (enExample)
SG (2) SG11201502634TA (enExample)
WO (3) WO2014060389A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201218660D0 (en) 2012-10-17 2012-11-28 Glaxosmithkline Biolog Sa Immunogenic composition
US11160855B2 (en) 2014-01-21 2021-11-02 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof
CN104306965B (zh) * 2014-10-31 2017-05-10 康希诺生物股份公司 预防肺炎链球菌感染性疾病的免疫原性组合物及制备方法
EP3325008B1 (en) * 2015-07-21 2025-09-10 Pfizer Inc. Immunogenic compositions comprising conjugated capsular saccharide antigens, kits comprising the same and uses thereof
GB201518684D0 (en) * 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
GB201603029D0 (en) * 2016-02-22 2016-04-06 Glaxosmithkline Biolog Sa Vaccine
CN106432512B (zh) * 2016-09-30 2022-03-01 康希诺生物股份公司 一种增强多糖抗原免疫原性蛋白载体及其制备方法与应用
WO2019143911A1 (en) * 2018-01-19 2019-07-25 Obi Pharma, Inc. Crm197 protein expression
CN110540597B (zh) * 2018-12-20 2021-04-30 湖北工业大学 基于流感嗜血杆菌表面蛋白的乳胶微球免疫层析试纸的制备方法
MX2022013456A (es) * 2020-05-01 2022-11-16 Sinocelltech Ltd Metodo para mejorar la inmunogenicidad de un antigeno proteinico/peptidico.
KR20220142219A (ko) * 2021-04-14 2022-10-21 한국생명공학연구원 장내 미생물에서 단백질 분비를 유도하는 신호서열
EP4169513A1 (en) 2021-10-19 2023-04-26 GlaxoSmithKline Biologicals S.A. Adjuvant composition comprising sting agonists
CN117512031B (zh) * 2023-10-16 2024-06-25 江苏金迪克生物技术股份有限公司 一种肺炎球菌荚膜多糖的纯化方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100642044B1 (ko) * 1999-03-19 2006-11-10 글락소스미스클라인 바이오로지칼즈 에스.에이. 백신
GB0108364D0 (en) * 2001-04-03 2001-05-23 Glaxosmithkline Biolog Sa Vaccine composition
OA12302A (en) * 2000-06-29 2003-10-24 Glaxosmithkline Biolog Sa Multivalent vaccine composition.
GB0022742D0 (en) * 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
GB0130215D0 (en) * 2001-12-18 2002-02-06 Glaxosmithkline Biolog Sa Vaccine
ATE461937T1 (de) * 2003-12-23 2010-04-15 Nationwide Childrens Hospital Pili von haemophilus influenzae typ iv
CA2613970C (en) * 2005-07-08 2015-12-08 Children's Hospital, Inc. Chimeric vaccine for haemophilus influenzae-induced disease
SG10201600336RA (en) * 2006-01-17 2016-02-26 Arne Forsgren A novel surface exposed haemophilus influenzae protein (protein e; pe)
MX2009013949A (es) * 2007-06-26 2010-05-24 Glaxosmithkline Biolog Sa Vacuna que comprende conjugados de polisacárido capsular de streptococcus pneumoniae.
EP2376526A4 (en) * 2008-12-24 2013-02-27 Kingdom Of The Netherlands Represented By The Min Ister Of Health Welfare & Sport On Behalf Of The M MODIFIED STREPTOCOCCUS PNEUMONIAE PNEUMOLYSIN (PLY) POLYPEPTIDE
PE20121544A1 (es) * 2009-09-03 2012-12-02 Pfizer Vaccines Llc Vacuna de pcsk9
US20130183350A1 (en) * 2009-12-22 2013-07-18 Kevin Harper Immunogenic compositions
WO2012075428A1 (en) * 2010-12-03 2012-06-07 Sanofi Pasteur Limited Composition for immunization against streptococcus pneumoniae
CA2830879C (en) * 2011-03-22 2018-10-30 Serum Institute Of India Ltd. A novel process for preparation of polysaccharides
TW201302779A (zh) * 2011-04-13 2013-01-16 Glaxosmithkline Biolog Sa 融合蛋白質及組合疫苗
US20140072622A1 (en) * 2011-05-17 2014-03-13 Glaxosmithkline Biologicals S.A. Vaccine against streptococcus pneumoniae

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