EA201590490A1 - ИММУНОГЕННАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ОДИН ИЛИ БОЛЕЕ КОНЪЮГАТОВ КАПСУЛЬНЫХ САХАРИДОВ STREPTOCOCCUS PNEUMONIAE И БЕЛКОВЫЙ КОМПОНЕНТ, ВКЛЮЧАЮЩИЙ БЕЛОК Е И/ИЛИ PilA ИЗ HAEMOPHILIUS INFLUENZAE - Google Patents
ИММУНОГЕННАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ОДИН ИЛИ БОЛЕЕ КОНЪЮГАТОВ КАПСУЛЬНЫХ САХАРИДОВ STREPTOCOCCUS PNEUMONIAE И БЕЛКОВЫЙ КОМПОНЕНТ, ВКЛЮЧАЮЩИЙ БЕЛОК Е И/ИЛИ PilA ИЗ HAEMOPHILIUS INFLUENZAEInfo
- Publication number
- EA201590490A1 EA201590490A1 EA201590490A EA201590490A EA201590490A1 EA 201590490 A1 EA201590490 A1 EA 201590490A1 EA 201590490 A EA201590490 A EA 201590490A EA 201590490 A EA201590490 A EA 201590490A EA 201590490 A1 EA201590490 A1 EA 201590490A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- protein
- pila
- streptococcus pneumoniae
- sucharides
- immunogenous
- Prior art date
Links
- 241001377010 Pila Species 0.000 title abstract 2
- 241000193998 Streptococcus pneumoniae Species 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 235000004252 protein component Nutrition 0.000 title abstract 2
- 229940031000 streptococcus pneumoniae Drugs 0.000 title abstract 2
- 235000018102 proteins Nutrition 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 101710204837 Envelope small membrane protein Proteins 0.000 abstract 1
- 241000606768 Haemophilus influenzae Species 0.000 abstract 1
- 101710088839 Replication initiation protein Proteins 0.000 abstract 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 1
- 229940047650 haemophilus influenzae Drugs 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
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- A61K39/08—Clostridium, e.g. Clostridium tetani
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- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
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- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/32011—Picornaviridae
- C12N2770/32611—Poliovirus
- C12N2770/32634—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- AIDS & HIV (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261714942P | 2012-10-17 | 2012-10-17 | |
| US201261714956P | 2012-10-17 | 2012-10-17 | |
| GBGB1218660.7A GB201218660D0 (en) | 2012-10-17 | 2012-10-17 | Immunogenic composition |
| US13/826,932 US20140193451A1 (en) | 2012-10-17 | 2013-03-14 | Immunogenic composition |
| US13/827,203 US20140105927A1 (en) | 2012-10-17 | 2013-03-14 | Immunogenic composition |
| US13/826,696 US9561268B2 (en) | 2012-10-17 | 2013-03-14 | Immunogenic composition |
| PCT/EP2013/071472 WO2014060383A1 (en) | 2012-10-17 | 2013-10-15 | Immunogenic composition comprising 1 or more streptococcus pneumoniae capsular saccharide conjugates and a protein component comprising protein e and/or pila fromhaemophilus influenzae. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA201590490A1 true EA201590490A1 (ru) | 2015-10-30 |
Family
ID=53008966
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201590490A EA201590490A1 (ru) | 2012-10-17 | 2013-10-15 | ИММУНОГЕННАЯ КОМПОЗИЦИЯ, СОДЕРЖАЩАЯ ОДИН ИЛИ БОЛЕЕ КОНЪЮГАТОВ КАПСУЛЬНЫХ САХАРИДОВ STREPTOCOCCUS PNEUMONIAE И БЕЛКОВЫЙ КОМПОНЕНТ, ВКЛЮЧАЮЩИЙ БЕЛОК Е И/ИЛИ PilA ИЗ HAEMOPHILIUS INFLUENZAE |
| EA201590491A EA201590491A1 (ru) | 2012-10-17 | 2013-10-15 | Иммуногенная композиция |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201590491A EA201590491A1 (ru) | 2012-10-17 | 2013-10-15 | Иммуногенная композиция |
Country Status (13)
| Country | Link |
|---|---|
| EP (3) | EP2908855B1 (enExample) |
| JP (3) | JP6236086B2 (enExample) |
| KR (2) | KR20150058571A (enExample) |
| CN (2) | CN104853768B (enExample) |
| AU (2) | AU2013331781A1 (enExample) |
| BR (3) | BR112015008418A2 (enExample) |
| CA (3) | CA2888300A1 (enExample) |
| EA (2) | EA201590490A1 (enExample) |
| ES (1) | ES2640320T3 (enExample) |
| IL (2) | IL238053A0 (enExample) |
| MX (2) | MX365842B (enExample) |
| SG (2) | SG11201502634TA (enExample) |
| WO (3) | WO2014060385A1 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201218660D0 (en) | 2012-10-17 | 2012-11-28 | Glaxosmithkline Biolog Sa | Immunogenic composition |
| US11160855B2 (en) | 2014-01-21 | 2021-11-02 | Pfizer Inc. | Immunogenic compositions comprising conjugated capsular saccharide antigens and uses thereof |
| CN104306965B (zh) * | 2014-10-31 | 2017-05-10 | 康希诺生物股份公司 | 预防肺炎链球菌感染性疾病的免疫原性组合物及制备方法 |
| KR102800419B1 (ko) * | 2015-07-21 | 2025-04-25 | 화이자 인코포레이티드 | 접합된 캡슐형 사카라이드 항원을 포함하는 면역원성 조성물, 그를 포함하는 키트 및 그의 용도 |
| GB201518684D0 (en) * | 2015-10-21 | 2015-12-02 | Glaxosmithkline Biolog Sa | Vaccine |
| GB201603029D0 (en) * | 2016-02-22 | 2016-04-06 | Glaxosmithkline Biolog Sa | Vaccine |
| CN106432512B (zh) * | 2016-09-30 | 2022-03-01 | 康希诺生物股份公司 | 一种增强多糖抗原免疫原性蛋白载体及其制备方法与应用 |
| KR20200111685A (ko) * | 2018-01-19 | 2020-09-29 | 오비아이 파머 인코퍼레이티드 | Crm197 단백질 발현 |
| CN110540597B (zh) * | 2018-12-20 | 2021-04-30 | 湖北工业大学 | 基于流感嗜血杆菌表面蛋白的乳胶微球免疫层析试纸的制备方法 |
| EP4144365A4 (en) * | 2020-05-01 | 2024-06-05 | Sinocelltech Ltd. | METHODS FOR IMPROVING THE IMMUNOGENERICITY OF PROTEIN/PEPTIDE ANTIGEN |
| KR20220142219A (ko) * | 2021-04-14 | 2022-10-21 | 한국생명공학연구원 | 장내 미생물에서 단백질 분비를 유도하는 신호서열 |
| EP4169513A1 (en) | 2021-10-19 | 2023-04-26 | GlaxoSmithKline Biologicals S.A. | Adjuvant composition comprising sting agonists |
| CN117512031B (zh) * | 2023-10-16 | 2024-06-25 | 江苏金迪克生物技术股份有限公司 | 一种肺炎球菌荚膜多糖的纯化方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1162999B1 (en) * | 1999-03-19 | 2006-11-29 | Glaxosmithkline Biologicals S.A. | Vaccine against Streptococcus pneumoniae |
| GB0108364D0 (en) * | 2001-04-03 | 2001-05-23 | Glaxosmithkline Biolog Sa | Vaccine composition |
| CZ20024224A3 (cs) * | 2000-06-29 | 2003-05-14 | Glaxosmithkline Biologicals S. A. | Farmaceutický prostředek |
| GB0022742D0 (en) * | 2000-09-15 | 2000-11-01 | Smithkline Beecham Biolog | Vaccine |
| GB0130215D0 (en) * | 2001-12-18 | 2002-02-06 | Glaxosmithkline Biolog Sa | Vaccine |
| ES2387215T3 (es) * | 2003-12-23 | 2012-09-18 | Nationwide Children's Hospital, Inc. | Pili de tipo IV de la Haemophilus influenzae |
| ATE488526T1 (de) * | 2005-07-08 | 2010-12-15 | Nationwide Childrens Hospital | Chimärer impfstoff für haemophilus influenzae- induzierte infektion |
| NO346497B1 (no) * | 2006-01-17 | 2022-09-05 | Arne Forsgren | Overflateeksponert haemophilus influenzae protein (protein E, pE) |
| US9610339B2 (en) * | 2007-06-26 | 2017-04-04 | Glaxosmithkline Biologicals, S.A. | Vaccine comprising Streptococcus pneumoniae capsular polysaccharide conjugates |
| BRPI0923649A2 (pt) * | 2008-12-24 | 2016-01-19 | Netherlands Vaccine Inst | polipeptídeos de pneumolisina (ply) de streptococcus pneumoniae modificados. |
| ES2670576T3 (es) * | 2009-09-03 | 2018-05-31 | Pfizer Vaccines Llc | Vacuna de PCSK9 |
| US20130183350A1 (en) * | 2009-12-22 | 2013-07-18 | Kevin Harper | Immunogenic compositions |
| CA2819758A1 (en) * | 2010-12-03 | 2012-06-07 | Sanofi Pasteur Limited | Composition for immunization against streptococcus pneumoniae |
| CN103687600B (zh) * | 2011-03-22 | 2016-05-04 | 印度血清研究所私人有限公司 | 一种制备多糖的方法 |
| TW201302779A (zh) * | 2011-04-13 | 2013-01-16 | Glaxosmithkline Biolog Sa | 融合蛋白質及組合疫苗 |
| BR112013029514A2 (pt) * | 2011-05-17 | 2019-09-24 | Glaxosmithkline Biologicals Sa | composição imunogênica, vacina, e, método de tratar ou impedir uma doença |
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2013
- 2013-10-15 CN CN201380066113.5A patent/CN104853768B/zh not_active Expired - Fee Related
- 2013-10-15 SG SG11201502634TA patent/SG11201502634TA/en unknown
- 2013-10-15 EP EP13779190.1A patent/EP2908855B1/en active Active
- 2013-10-15 CA CA2888300A patent/CA2888300A1/en not_active Abandoned
- 2013-10-15 JP JP2015537216A patent/JP6236086B2/ja active Active
- 2013-10-15 WO PCT/EP2013/071477 patent/WO2014060385A1/en not_active Ceased
- 2013-10-15 CN CN201380066162.9A patent/CN104968366B/zh active Active
- 2013-10-15 BR BR112015008418A patent/BR112015008418A2/pt not_active IP Right Cessation
- 2013-10-15 MX MX2015004949A patent/MX365842B/es active IP Right Grant
- 2013-10-15 KR KR1020157013037A patent/KR20150058571A/ko not_active Withdrawn
- 2013-10-15 EP EP13779191.9A patent/EP2908856B1/en active Active
- 2013-10-15 CA CA2888321A patent/CA2888321A1/en not_active Abandoned
- 2013-10-15 JP JP2015537220A patent/JP2015534964A/ja active Pending
- 2013-10-15 EP EP13776808.1A patent/EP2908854A2/en not_active Ceased
- 2013-10-15 BR BR112015008419-2A patent/BR112015008419B1/pt active IP Right Grant
- 2013-10-15 ES ES13779190.1T patent/ES2640320T3/es active Active
- 2013-10-15 KR KR1020157013039A patent/KR20150072444A/ko not_active Withdrawn
- 2013-10-15 JP JP2015537218A patent/JP6412500B2/ja not_active Expired - Fee Related
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- 2013-10-15 EA EA201590490A patent/EA201590490A1/ru unknown
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