JP2015535216A - ヒマワリからカフェオイルキナ酸に富んだ抽出物を得る方法 - Google Patents
ヒマワリからカフェオイルキナ酸に富んだ抽出物を得る方法 Download PDFInfo
- Publication number
- JP2015535216A JP2015535216A JP2015536096A JP2015536096A JP2015535216A JP 2015535216 A JP2015535216 A JP 2015535216A JP 2015536096 A JP2015536096 A JP 2015536096A JP 2015536096 A JP2015536096 A JP 2015536096A JP 2015535216 A JP2015535216 A JP 2015535216A
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- JP
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- Prior art keywords
- sunflower
- extract
- solution
- extraction
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000284 extract Substances 0.000 title claims abstract description 43
- 238000000034 method Methods 0.000 title claims abstract description 16
- PZIRUHCJZBGLDY-UHFFFAOYSA-N Caffeoylquinic acid Natural products CC(CCC(=O)C(C)C1C(=O)CC2C3CC(O)C4CC(O)CCC4(C)C3CCC12C)C(=O)O PZIRUHCJZBGLDY-UHFFFAOYSA-N 0.000 title claims description 17
- 241000208818 Helianthus Species 0.000 title claims description 17
- 235000003222 Helianthus annuus Nutrition 0.000 title claims description 17
- CWVRJTMFETXNAD-GMZLATJGSA-N 5-Caffeoyl quinic acid Natural products O[C@H]1C[C@](O)(C[C@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-GMZLATJGSA-N 0.000 title claims description 15
- CWVRJTMFETXNAD-NXLLHMKUSA-N trans-5-O-caffeoyl-D-quinic acid Chemical compound O[C@H]1[C@H](O)C[C@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-NXLLHMKUSA-N 0.000 title claims 2
- 239000000203 mixture Substances 0.000 claims abstract description 19
- 235000013305 food Nutrition 0.000 claims abstract description 11
- 150000001720 carbohydrates Chemical class 0.000 claims abstract description 7
- 238000010521 absorption reaction Methods 0.000 claims abstract description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 18
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 12
- 239000007864 aqueous solution Substances 0.000 claims description 10
- 238000000605 extraction Methods 0.000 claims description 10
- 239000002775 capsule Substances 0.000 claims description 9
- 239000000243 solution Substances 0.000 claims description 9
- 239000012528 membrane Substances 0.000 claims description 7
- 238000009472 formulation Methods 0.000 claims description 6
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims description 6
- 238000001728 nano-filtration Methods 0.000 claims description 6
- 229920005989 resin Polymers 0.000 claims description 6
- 239000011347 resin Substances 0.000 claims description 6
- 235000020238 sunflower seed Nutrition 0.000 claims description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 4
- QAOWNCQODCNURD-UHFFFAOYSA-N Sulfuric acid Chemical compound OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 claims description 4
- 238000004587 chromatography analysis Methods 0.000 claims description 4
- 239000002904 solvent Substances 0.000 claims description 4
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- 235000021118 plant-derived protein Nutrition 0.000 claims 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract description 10
- 239000008103 glucose Substances 0.000 abstract description 10
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- 229940119463 sunflower seed extract Drugs 0.000 abstract 1
- CWVRJTMFETXNAD-JUHZACGLSA-N chlorogenic acid Chemical compound O[C@@H]1[C@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-JUHZACGLSA-N 0.000 description 15
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- 150000003839 salts Chemical class 0.000 description 4
- 239000002028 Biomass Substances 0.000 description 3
- 235000001368 chlorogenic acid Nutrition 0.000 description 3
- 230000000717 retained effect Effects 0.000 description 3
- 235000000346 sugar Nutrition 0.000 description 3
- CWVRJTMFETXNAD-FWCWNIRPSA-N 3-O-Caffeoylquinic acid Natural products O[C@H]1[C@@H](O)C[C@@](O)(C(O)=O)C[C@H]1OC(=O)\C=C\C1=CC=C(O)C(O)=C1 CWVRJTMFETXNAD-FWCWNIRPSA-N 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- CWVRJTMFETXNAD-KLZCAUPSSA-N Neochlorogenin-saeure Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O CWVRJTMFETXNAD-KLZCAUPSSA-N 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 230000003078 antioxidant effect Effects 0.000 description 2
- 230000001580 bacterial effect Effects 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 235000015895 biscuits Nutrition 0.000 description 2
- 235000008429 bread Nutrition 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 229940074393 chlorogenic acid Drugs 0.000 description 2
- FFQSDFBBSXGVKF-KHSQJDLVSA-N chlorogenic acid Natural products O[C@@H]1C[C@](O)(C[C@@H](CC(=O)C=Cc2ccc(O)c(O)c2)[C@@H]1O)C(=O)O FFQSDFBBSXGVKF-KHSQJDLVSA-N 0.000 description 2
- BMRSEYFENKXDIS-KLZCAUPSSA-N cis-3-O-p-coumaroylquinic acid Natural products O[C@H]1C[C@@](O)(C[C@@H](OC(=O)C=Cc2ccc(O)cc2)[C@@H]1O)C(=O)O BMRSEYFENKXDIS-KLZCAUPSSA-N 0.000 description 2
- 238000004807 desolvation Methods 0.000 description 2
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- 235000012054 meals Nutrition 0.000 description 2
- 239000012466 permeate Substances 0.000 description 2
- 239000000902 placebo Substances 0.000 description 2
- 229940068196 placebo Drugs 0.000 description 2
- 150000008442 polyphenolic compounds Chemical class 0.000 description 2
- 235000013824 polyphenols Nutrition 0.000 description 2
- 230000003389 potentiating effect Effects 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 150000008163 sugars Chemical class 0.000 description 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 description 2
- AAWZDTNXLSGCEK-LNVDRNJUSA-N (3r,5r)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid Chemical compound O[C@@H]1CC(O)(C(O)=O)C[C@@H](O)C1O AAWZDTNXLSGCEK-LNVDRNJUSA-N 0.000 description 1
- QNIFYGWWBZKEGO-JAIMSRQGSA-N C(\C=C\C1=CC(O)=C(O)C=C1)(=O)C1([C@@H](CC(C[C@H]1O)(C(=O)O)O)O)O Chemical compound C(\C=C\C1=CC(O)=C(O)C=C1)(=O)C1([C@@H](CC(C[C@H]1O)(C(=O)O)O)O)O QNIFYGWWBZKEGO-JAIMSRQGSA-N 0.000 description 1
- AAWZDTNXLSGCEK-UHFFFAOYSA-N Cordycepinsaeure Natural products OC1CC(O)(C(O)=O)CC(O)C1O AAWZDTNXLSGCEK-UHFFFAOYSA-N 0.000 description 1
- YDDUMTOHNYZQPO-RVXRWRFUSA-N Cynarine Chemical compound O([C@@H]1C[C@@](C[C@H]([C@@H]1O)O)(OC(=O)\C=C\C=1C=C(O)C(O)=CC=1)C(O)=O)C(=O)\C=C\C1=CC=C(O)C(O)=C1 YDDUMTOHNYZQPO-RVXRWRFUSA-N 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- 239000001828 Gelatine Substances 0.000 description 1
- 102000003886 Glycoproteins Human genes 0.000 description 1
- 108090000288 Glycoproteins Proteins 0.000 description 1
- 244000020551 Helianthus annuus Species 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 102000003960 Ligases Human genes 0.000 description 1
- 108090000364 Ligases Proteins 0.000 description 1
- 235000001412 Mediterranean diet Nutrition 0.000 description 1
- 238000006957 Michael reaction Methods 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 239000004793 Polystyrene Substances 0.000 description 1
- AAWZDTNXLSGCEK-ZHQZDSKASA-N Quinic acid Natural products O[C@H]1CC(O)(C(O)=O)C[C@H](O)C1O AAWZDTNXLSGCEK-ZHQZDSKASA-N 0.000 description 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 1
- 235000014680 Saccharomyces cerevisiae Nutrition 0.000 description 1
- 235000019486 Sunflower oil Nutrition 0.000 description 1
- 102000003929 Transaminases Human genes 0.000 description 1
- 108090000340 Transaminases Proteins 0.000 description 1
- 230000002745 absorbent Effects 0.000 description 1
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- 150000007513 acids Chemical group 0.000 description 1
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- 238000006243 chemical reaction Methods 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 229950009125 cynarine Drugs 0.000 description 1
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- 238000006731 degradation reaction Methods 0.000 description 1
- 150000005690 diesters Chemical class 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
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- 230000007071 enzymatic hydrolysis Effects 0.000 description 1
- 238000006047 enzymatic hydrolysis reaction Methods 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 229930003935 flavonoid Natural products 0.000 description 1
- 150000002215 flavonoids Chemical class 0.000 description 1
- 235000017173 flavonoids Nutrition 0.000 description 1
- 235000013312 flour Nutrition 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 125000005456 glyceride group Chemical group 0.000 description 1
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- 230000031891 intestinal absorption Effects 0.000 description 1
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- 125000004151 quinonyl group Chemical group 0.000 description 1
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- 239000000758 substrate Substances 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A21—BAKING; EDIBLE DOUGHS
- A21D—TREATMENT OF FLOUR OR DOUGH FOR BAKING, e.g. BY ADDITION OF MATERIALS; BAKING; BAKERY PRODUCTS
- A21D2/00—Treatment of flour or dough by adding materials thereto before or during baking
- A21D2/08—Treatment of flour or dough by adding materials thereto before or during baking by adding organic substances
- A21D2/24—Organic nitrogen compounds
- A21D2/26—Proteins
- A21D2/264—Vegetable proteins
- A21D2/266—Vegetable proteins from leguminous or other vegetable seeds; from press-cake or oil bearing seeds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Botany (AREA)
- Food Science & Technology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Medical Informatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nutrition Science (AREA)
- Polymers & Plastics (AREA)
- Emergency Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Child & Adolescent Psychology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI2012A001749 | 2012-10-16 | ||
| IT001749A ITMI20121749A1 (it) | 2012-10-16 | 2012-10-16 | Estratti di helianthus annuus utili nel trattamento della sindrome metabolica e nella diminuzione dell'indice glicemico di alimenti e procedimento per la loro preparazione e composizioni che li contengono |
| PCT/EP2013/070928 WO2014060244A1 (en) | 2012-10-16 | 2013-10-08 | Process for obtaining caffeoylquinic acids-rich extracts from helianthus annuus |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2015535216A true JP2015535216A (ja) | 2015-12-10 |
Family
ID=47425209
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015536096A Withdrawn JP2015535216A (ja) | 2012-10-16 | 2013-10-08 | ヒマワリからカフェオイルキナ酸に富んだ抽出物を得る方法 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20150258155A1 (https=) |
| EP (1) | EP2908663A1 (https=) |
| JP (1) | JP2015535216A (https=) |
| KR (1) | KR20150068959A (https=) |
| CN (1) | CN104717892A (https=) |
| AU (1) | AU2013331918B2 (https=) |
| BR (1) | BR112015008075A2 (https=) |
| CA (1) | CA2888305A1 (https=) |
| HK (1) | HK1211439A1 (https=) |
| IL (1) | IL238272A0 (https=) |
| IN (1) | IN2015DN03104A (https=) |
| IT (1) | ITMI20121749A1 (https=) |
| RU (1) | RU2015113521A (https=) |
| SG (1) | SG11201502908TA (https=) |
| WO (1) | WO2014060244A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6129762B2 (ja) * | 2013-10-04 | 2017-05-17 | 富士フイルム株式会社 | クロロゲン酸含有組成物の製造方法 |
| JP6756721B2 (ja) * | 2015-09-17 | 2020-09-16 | 三栄源エフ・エフ・アイ株式会社 | ヘリアンサス属植物種子抽出物及びその製造方法 |
| EP3691468A4 (en) | 2017-10-06 | 2021-10-20 | Cargill, Incorporated | EASILY SOLUBLE STEVIOL GLYCOSIDE COMPOSITIONS |
| MY205266A (en) | 2019-04-06 | 2024-10-10 | Cargill Inc | Methods for making botanical extract composition |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100421689C (zh) * | 2003-08-26 | 2008-10-01 | 上海永恒生物科技有限公司 | 山楂总酚酸部位的制备工艺和应用 |
| CN100382798C (zh) * | 2006-01-20 | 2008-04-23 | 深圳市生物谷科技有限公司 | 一种含有咖啡酰奎宁酸的药物组合物 |
| ES2323815T3 (es) * | 2007-03-07 | 2009-07-24 | Indena S.P.A. | Formulaciones que contienen extractos de cynara scolymus y de phaseolus vulgaris que son utiles para el tratamiento de la obesidad. |
| CN101057674B (zh) * | 2007-06-13 | 2010-09-08 | 深圳市金沙江投资有限公司 | 一种用于防治糖尿病的组合物 |
| CN102000051B (zh) * | 2010-11-24 | 2011-12-21 | 山东省科学院生物研究所 | 5-咖啡酰奎宁酸在制备抗肿瘤药物中的应用 |
| RU2583292C2 (ru) * | 2010-11-24 | 2016-05-10 | Као Корпорейшн | Способ производства экстракта из обжаренных зерен кофе |
| CN102100720B (zh) * | 2011-02-15 | 2012-03-28 | 江西本草天工科技有限责任公司 | 杏香兔耳风咖啡酰奎宁酸类提取物及其制备与应用 |
| CN102617667B (zh) * | 2012-03-05 | 2014-07-30 | 南京师范大学 | 一种以甜叶菊为原料同时制备总咖啡酰奎尼酸和甜菊糖的方法 |
-
2012
- 2012-10-16 IT IT001749A patent/ITMI20121749A1/it unknown
-
2013
- 2013-10-08 KR KR1020157009581A patent/KR20150068959A/ko not_active Withdrawn
- 2013-10-08 BR BR112015008075A patent/BR112015008075A2/pt not_active IP Right Cessation
- 2013-10-08 SG SG11201502908TA patent/SG11201502908TA/en unknown
- 2013-10-08 IN IN3104DEN2015 patent/IN2015DN03104A/en unknown
- 2013-10-08 CA CA2888305A patent/CA2888305A1/en not_active Abandoned
- 2013-10-08 CN CN201380053559.4A patent/CN104717892A/zh active Pending
- 2013-10-08 WO PCT/EP2013/070928 patent/WO2014060244A1/en not_active Ceased
- 2013-10-08 HK HK15112386.0A patent/HK1211439A1/xx unknown
- 2013-10-08 EP EP13785371.9A patent/EP2908663A1/en not_active Withdrawn
- 2013-10-08 US US14/433,351 patent/US20150258155A1/en not_active Abandoned
- 2013-10-08 JP JP2015536096A patent/JP2015535216A/ja not_active Withdrawn
- 2013-10-08 AU AU2013331918A patent/AU2013331918B2/en not_active Ceased
- 2013-10-08 RU RU2015113521A patent/RU2015113521A/ru not_active Application Discontinuation
-
2015
- 2015-04-14 IL IL238272A patent/IL238272A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20150258155A1 (en) | 2015-09-17 |
| CA2888305A1 (en) | 2014-04-24 |
| AU2013331918B2 (en) | 2017-01-12 |
| CN104717892A (zh) | 2015-06-17 |
| RU2015113521A (ru) | 2016-12-10 |
| WO2014060244A1 (en) | 2014-04-24 |
| ITMI20121749A1 (it) | 2014-04-17 |
| SG11201502908TA (en) | 2015-06-29 |
| IN2015DN03104A (https=) | 2015-10-02 |
| BR112015008075A2 (pt) | 2017-07-04 |
| HK1211439A1 (en) | 2016-05-27 |
| KR20150068959A (ko) | 2015-06-22 |
| AU2013331918A1 (en) | 2015-05-07 |
| IL238272A0 (en) | 2015-06-30 |
| EP2908663A1 (en) | 2015-08-26 |
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