JP2015530404A5 - - Google Patents
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- JP2015530404A5 JP2015530404A5 JP2015532965A JP2015532965A JP2015530404A5 JP 2015530404 A5 JP2015530404 A5 JP 2015530404A5 JP 2015532965 A JP2015532965 A JP 2015532965A JP 2015532965 A JP2015532965 A JP 2015532965A JP 2015530404 A5 JP2015530404 A5 JP 2015530404A5
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- active ingredient
- conjugate
- composition
- seq
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- 108090000765 processed proteins & peptides Proteins 0.000 claims 21
- 239000004480 active ingredient Substances 0.000 claims 13
- 239000002872 contrast media Substances 0.000 claims 11
- 239000000203 mixture Substances 0.000 claims 9
- 210000004027 cell Anatomy 0.000 claims 5
- 239000012634 fragment Substances 0.000 claims 4
- 108010043121 Green Fluorescent Proteins Proteins 0.000 claims 2
- 102000004144 Green Fluorescent Proteins Human genes 0.000 claims 2
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims 2
- 150000001413 amino acids Chemical class 0.000 claims 2
- 239000002537 cosmetic Substances 0.000 claims 2
- 239000005090 green fluorescent protein Substances 0.000 claims 2
- 235000013402 health food Nutrition 0.000 claims 2
- 102000040430 polynucleotide Human genes 0.000 claims 2
- 108091033319 polynucleotide Proteins 0.000 claims 2
- 239000002157 polynucleotide Substances 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 239000000126 substance Substances 0.000 claims 2
- 102000020313 Cell-Penetrating Peptides Human genes 0.000 claims 1
- 108010051109 Cell-Penetrating Peptides Proteins 0.000 claims 1
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- 229930186217 Glycolipid Natural products 0.000 claims 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 claims 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 claims 1
- 125000003275 alpha amino acid group Chemical group 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- MHMNJMPURVTYEJ-UHFFFAOYSA-N fluorescein-5-isothiocyanate Chemical compound O1C(=O)C2=CC(N=C=S)=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 MHMNJMPURVTYEJ-UHFFFAOYSA-N 0.000 claims 1
- 238000003384 imaging method Methods 0.000 claims 1
- 229910052500 inorganic mineral Inorganic materials 0.000 claims 1
- 229910052742 iron Inorganic materials 0.000 claims 1
- 239000003446 ligand Substances 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 230000001404 mediated effect Effects 0.000 claims 1
- 239000011707 mineral Substances 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 230000005298 paramagnetic effect Effects 0.000 claims 1
- 230000035699 permeability Effects 0.000 claims 1
- 239000008194 pharmaceutical composition Substances 0.000 claims 1
- 238000002360 preparation method Methods 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
- 210000000130 stem cell Anatomy 0.000 claims 1
- 235000000346 sugar Nutrition 0.000 claims 1
- 150000008163 sugars Chemical class 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2012-0104144 | 2012-09-19 | ||
| KR20120104144 | 2012-09-19 | ||
| KR10-2012-0109216 | 2012-09-28 | ||
| KR20120109216 | 2012-09-28 | ||
| KR10-2013-0017046 | 2013-02-18 | ||
| KR20130017169 | 2013-02-18 | ||
| KR10-2013-0017169 | 2013-02-18 | ||
| KR20130017046 | 2013-02-18 | ||
| PCT/KR2013/008445 WO2014046481A1 (ko) | 2012-09-19 | 2013-09-17 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015530404A JP2015530404A (ja) | 2015-10-15 |
| JP2015530404A5 true JP2015530404A5 (OSRAM) | 2016-11-10 |
| JP6510410B2 JP6510410B2 (ja) | 2019-05-08 |
Family
ID=50341702
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015532965A Active JP6510410B2 (ja) | 2012-09-19 | 2013-09-17 | 細胞透過性ペプチド、それを含んだコンジュゲート、及びそれを含んだ組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9631184B2 (OSRAM) |
| EP (1) | EP2899199B1 (OSRAM) |
| JP (1) | JP6510410B2 (OSRAM) |
| KR (1) | KR102201430B1 (OSRAM) |
| CN (3) | CN110064056B (OSRAM) |
| ES (1) | ES2743919T3 (OSRAM) |
| TW (1) | TWI598441B (OSRAM) |
| WO (1) | WO2014046481A1 (OSRAM) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115927242A (zh) | 2012-05-11 | 2023-04-07 | 珍白斯凯尔有限公司 | 具有抗炎活性的肽及其在制备抗炎组合物中的应用 |
| CN104507489B (zh) | 2012-05-11 | 2016-07-13 | 杰姆维克斯&凯尔有限公司 | 用于预防和治疗类风湿性关节炎的组合物 |
| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| US20150125438A1 (en) | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
| CN107312759B (zh) | 2012-09-19 | 2025-10-28 | 珍白斯凯尔有限公司 | 细胞穿透肽、包含该肽的缀合物、及包含该缀合物的组合物 |
| TWI655204B (zh) | 2012-09-19 | 2019-04-01 | 韓商傑姆維克斯＆凱爾有限公司 | 穿膜胜肽以及包含該胜肽之共軛物及組成物(三) |
| ES2716870T3 (es) | 2013-04-19 | 2019-06-17 | Gemvax & Kael Co Ltd | Composición para el tratamiento y prevención de lesión isquémica |
| CN105535931A (zh) | 2013-06-07 | 2016-05-04 | 凯尔杰姆维克斯有限公司 | 在癌症免疫疗法中有用的生物标记 |
| EP3011967B1 (en) | 2013-06-21 | 2020-06-17 | Gemvax & Kael Co., Ltd. | Hormone secretion regulator, composition containing same, and method for controlling hormone secretion using same |
| WO2015005723A1 (ko) * | 2013-07-12 | 2015-01-15 | 주식회사 카엘젬백스 | 세포 투과성 펩티드 및 이를 포함하는 컨쥬게이트 |
| JP6382972B2 (ja) | 2013-10-23 | 2018-08-29 | ジェムバックス アンド カエル カンパニー，リミティド | 前立腺肥大治療用及びその予防用の組成物 |
| JP6553605B2 (ja) | 2013-11-22 | 2019-07-31 | ジェムバックス アンド カエル カンパニー，リミティド | 血管新生抑制活性を有するペプチド、及びそれを含む組成物 |
| JP6367950B2 (ja) | 2013-12-17 | 2018-08-01 | ジェムバックス アンド カエル カンパニー，リミティド | 前立腺癌治療用組成物 |
| CN106456697B (zh) | 2014-04-11 | 2019-12-17 | 珍白斯凯尔有限公司 | 具有纤维化抑制活性的肽和含有其的组合物 |
| KR102232320B1 (ko) | 2014-04-30 | 2021-03-26 | 주식회사 젬백스앤카엘 | 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법 |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| CN107405380B (zh) | 2015-02-27 | 2021-04-20 | 珍白斯凯尔有限公司 | 用于预防听觉损伤的肽及其包含该肽的组合物 |
| WO2016190660A1 (ko) | 2015-05-26 | 2016-12-01 | 주식회사 젬백스앤카엘 | 신규 펩티드 및 이를 포함한 조성물 |
| EP3318265B1 (en) | 2015-07-02 | 2021-08-18 | Gemvax & Kael Co., Ltd. | Peptide having anti-viral effect and composition containing same |
| CN108431021B (zh) * | 2015-11-03 | 2021-09-07 | 珍白斯凯尔有限公司 | 具有神经元损失预防和再生效果的肽以及包含该肽的组合物 |
| KR101661912B1 (ko) | 2016-01-29 | 2016-10-04 | (주)넥스젠바이오텍 | 녹색형광단백질-인간 상피세포재생인자 융합단백질을 유효성분으로 포함하는 주름 개선 및 항노화 화장료 조성물 |
| ES2949697T3 (es) | 2016-04-07 | 2023-10-02 | Gemvax & Kael Co Ltd | Péptido que tiene efectos de aumento de la actividad telomerasa y de extensión de los telómeros, y composición que contienen el mismo |
| WO2017180587A2 (en) | 2016-04-11 | 2017-10-19 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| EP3806888B1 (en) | 2018-06-12 | 2024-01-31 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
| US20210386788A1 (en) | 2018-10-24 | 2021-12-16 | Obsidian Therapeutics, Inc. | Er tunable protein regulation |
| WO2021046451A1 (en) | 2019-09-06 | 2021-03-11 | Obsidian Therapeutics, Inc. | Compositions and methods for dhfr tunable protein regulation |
| WO2021225344A1 (ko) * | 2020-05-08 | 2021-11-11 | 한림대학교 산학협력단 | 코로나 바이러스 억제용 펩타이드 및 그 용도 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL129222A0 (en) * | 1996-10-01 | 2000-02-17 | Geron Corp | Telomerase reverse transcriptase |
| US6610839B1 (en) * | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| US7030211B1 (en) * | 1998-07-08 | 2006-04-18 | Gemvax As | Antigenic peptides derived from telomerase |
| GB0112342D0 (en) * | 2001-05-21 | 2001-07-11 | Norsk Hydro As | Polypeptides |
| WO2003038047A2 (en) * | 2001-10-29 | 2003-05-08 | Baylor College Of Medicine | Human telomerase reverse transcriptase as a class-ii restricted tumor-associated antigen |
| US7294708B2 (en) * | 2002-05-31 | 2007-11-13 | Beijing Institute Of Biotechnology | Telomerase reverse transcriptase fragments and uses thereof |
| WO2007069068A2 (en) | 2005-12-16 | 2007-06-21 | Diatos | Cell penetrating peptide conjugates for delivering nucleic acids into cells |
| EP1991560B1 (en) | 2006-02-20 | 2018-04-04 | Ewha University-Industry Collaboration Foundation | Peptide having cell membrane penetrating activity |
| JP5518488B2 (ja) * | 2007-01-29 | 2014-06-11 | プロセル セラピューティックス インコーポレーティッド | 巨大分子伝達ドメインならびにその同定方法および使用 |
| EP1994942A1 (en) * | 2007-05-25 | 2008-11-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Pharmaceutical compositions comprising telomerase, and uses thereof |
| ES2602453T3 (es) * | 2008-06-16 | 2017-02-21 | Mediolanum Farmaceutici S.P.A. | Inmunoterapia antitumoral |
| ES2334315B1 (es) | 2008-07-29 | 2011-02-28 | Universitat Pompeu Fabra | Peptidos con capacidad de penetracion celular y sus usos. |
| EP2337795A2 (en) * | 2008-10-01 | 2011-06-29 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
| KR101169030B1 (ko) | 2009-01-21 | 2012-07-26 | 애니젠 주식회사 | 신규한 세포막 투과 도메인 및 이를 포함하는 세포내 전달 시스템 |
| KR101783291B1 (ko) | 2009-05-20 | 2017-09-29 | 도레이 카부시키가이샤 | 세포막 투과성 펩티드 |
| CN108383894A (zh) | 2010-02-16 | 2018-08-10 | 阿尔特公司 | 多肽及其应用 |
| KR101263212B1 (ko) | 2010-05-28 | 2013-05-10 | 성신여자대학교 산학협력단 | 신규한 세포막 투과성 펩타이드 및 그의 용도 |
| WO2011150493A1 (en) | 2010-05-30 | 2011-12-08 | The Governing Council Of The University Of Toronto | Mitochondrial penetrating peptides as carriers for antimicrobials |
| KR101348284B1 (ko) * | 2010-09-09 | 2014-01-03 | 주식회사 나이벡 | 인간 유래 세포 투과성 펩타이드와 생리활성 펩타이드 결합체 및 그 용도 |
| CN115927242A (zh) | 2012-05-11 | 2023-04-07 | 珍白斯凯尔有限公司 | 具有抗炎活性的肽及其在制备抗炎组合物中的应用 |
| ES2981865T3 (es) | 2012-07-11 | 2024-10-10 | Gemvax & Kael Co Ltd | Conjugado que comprende un péptido de penetración celular y composiciones que comprenden el mismo |
| TWI655204B (zh) | 2012-09-19 | 2019-04-01 | 韓商傑姆維克斯＆凱爾有限公司 | 穿膜胜肽以及包含該胜肽之共軛物及組成物(三) |
| CN107312759B (zh) | 2012-09-19 | 2025-10-28 | 珍白斯凯尔有限公司 | 细胞穿透肽、包含该肽的缀合物、及包含该缀合物的组合物 |
| KR101778244B1 (ko) | 2014-05-13 | 2017-09-26 | 한양대학교 산학협력단 | 세포 투과성 펩티드 및 이를 이용한 생물학적 활성 물질의 전달방법 |
-
2013
- 2013-09-17 CN CN201910049089.3A patent/CN110064056B/zh active Active
- 2013-09-17 TW TW102133733A patent/TWI598441B/zh active
- 2013-09-17 CN CN201910048425.2A patent/CN110028554B/zh active Active
- 2013-09-17 ES ES13839102T patent/ES2743919T3/es active Active
- 2013-09-17 JP JP2015532965A patent/JP6510410B2/ja active Active
- 2013-09-17 WO PCT/KR2013/008445 patent/WO2014046481A1/ko not_active Ceased
- 2013-09-17 US US14/429,641 patent/US9631184B2/en active Active
- 2013-09-17 CN CN201380057722.4A patent/CN104768967B/zh active Active
- 2013-09-17 KR KR1020157009510A patent/KR102201430B1/ko active Active
- 2013-09-17 EP EP13839102.4A patent/EP2899199B1/en active Active
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