JP2012529293A5 - - Google Patents
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- Publication number
- JP2012529293A5 JP2012529293A5 JP2012514976A JP2012514976A JP2012529293A5 JP 2012529293 A5 JP2012529293 A5 JP 2012529293A5 JP 2012514976 A JP2012514976 A JP 2012514976A JP 2012514976 A JP2012514976 A JP 2012514976A JP 2012529293 A5 JP2012529293 A5 JP 2012529293A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- peptide
- motif
- terminus
- motifs
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims 32
- 238000000034 method Methods 0.000 claims 14
- 239000008194 pharmaceutical composition Substances 0.000 claims 7
- 150000001413 amino acids Chemical class 0.000 claims 6
- 102000040430 polynucleotide Human genes 0.000 claims 5
- 108091033319 polynucleotide Proteins 0.000 claims 5
- 239000002157 polynucleotide Substances 0.000 claims 5
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 4
- 125000003275 alpha amino acid group Chemical group 0.000 claims 3
- 239000013604 expression vector Substances 0.000 claims 2
- 208000030507 AIDS Diseases 0.000 claims 1
- 206010028980 Neoplasm Diseases 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 230000001105 regulatory effect Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21347109P | 2009-06-12 | 2009-06-12 | |
| US61/213,471 | 2009-06-12 | ||
| US12/783,829 | 2010-05-20 | ||
| US12/783,829 US8431530B2 (en) | 2009-06-12 | 2010-05-20 | Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles |
| PCT/US2010/035698 WO2010144231A2 (en) | 2009-06-12 | 2010-05-21 | Compositions and methods for treating aids or cancer by inhibiting the secretion of microparticles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012529293A JP2012529293A (ja) | 2012-11-22 |
| JP2012529293A5 true JP2012529293A5 (OSRAM) | 2013-01-24 |
Family
ID=43306940
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012514976A Ceased JP2012529293A (ja) | 2009-06-12 | 2010-05-21 | 微粒子の分泌を阻害することによりエイズまたは癌を治療することを目的とした組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (5) | US8431530B2 (OSRAM) |
| EP (1) | EP2440570B1 (OSRAM) |
| JP (1) | JP2012529293A (OSRAM) |
| CN (1) | CN102482325B (OSRAM) |
| CA (1) | CA2761121A1 (OSRAM) |
| WO (1) | WO2010144231A2 (OSRAM) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US12083158B2 (en) | 2011-10-07 | 2024-09-10 | Morehouse School Of Medicine | Antibacterial compositions, methods of making and use thereof |
| US8669226B2 (en) * | 2011-10-07 | 2014-03-11 | Morehouse School Of Medicine | Antimicrobial compositions and methods of use thereof |
| WO2013052058A1 (en) * | 2011-10-07 | 2013-04-11 | Morehouse School Of Medicine | Antimicrobial compositions and methods of use thereof |
| CN104619353A (zh) * | 2011-12-13 | 2015-05-13 | 俄亥俄州国家创新基金会 | 与miR-21和miR-29a相关的方法和组合物、外切体抑制和癌症转移 |
| US10702581B2 (en) | 2015-05-04 | 2020-07-07 | Ilias Biologics Inc. | Compositions containing protein loaded exosome and methods for preparing and delivering the same |
| EP3356522A4 (en) * | 2016-09-30 | 2019-03-27 | Cellex Life Sciences, Incorporated | COMPOSITIONS WITH PROTEIN-LOADED EXOSOME AND METHOD FOR THE PREPARATION AND RELEASE THEREOF |
| US10800817B2 (en) | 2016-12-19 | 2020-10-13 | Morehouse School Of Medicine | Compositions and methods for treating diseases by inhibiting exosome release |
| CN110312549B (zh) * | 2016-12-19 | 2021-06-29 | 莫尔豪斯医学院 | 用于通过抑制外泌体释放来治疗疾病的组合物和方法 |
| CN110799213A (zh) | 2017-06-01 | 2020-02-14 | 康姆普根有限公司 | 三联组合抗体疗法 |
| WO2020081634A2 (en) * | 2018-10-16 | 2020-04-23 | George Mason Research Foundation, Inc. | Compositions and methods for modulation of extracellular vesicle release and treatment of neurological disorders |
| US11180534B1 (en) | 2021-06-04 | 2021-11-23 | Morehouse School Of Medicine | Compositions and methods for treating SARS-CoV-2 infections |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2766205B1 (fr) | 1997-07-16 | 2002-08-30 | Inst Nat Sante Rech Med | Nouveau procede de sensibilisation de cellules presentatrices d'antigene et nouveaux moyens pour la mise en oeuvre du procede |
| FR2771640B1 (fr) | 1997-12-03 | 2000-02-11 | Inst Nat Sante Rech Med | Micelles mixtes de lipopeptides pour l'induction d'une reponse immunitaire et leurs utilisations a des fins therapeutiques |
| US6551795B1 (en) | 1998-02-18 | 2003-04-22 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics |
| ATE536187T1 (de) * | 2000-10-19 | 2011-12-15 | Epimmune Inc | Hla-klasse-i- und -klasse-ii-bindende peptide und ihre verwendungen |
| US20030229906A1 (en) | 2002-04-15 | 2003-12-11 | Gelman Irwin H. | Methods and compositions for the treatment of disorders of HIV infection |
| JP5022028B2 (ja) * | 2003-03-26 | 2012-09-12 | サイトス・バイオテクノロジー・アクチェンゲゼルシャフト | メラン−ａペプチドアナログ−ウイルス様粒子コンジュゲート |
-
2010
- 2010-05-20 US US12/783,829 patent/US8431530B2/en active Active
- 2010-05-21 WO PCT/US2010/035698 patent/WO2010144231A2/en not_active Ceased
- 2010-05-21 CN CN201080025184.7A patent/CN102482325B/zh active Active
- 2010-05-21 JP JP2012514976A patent/JP2012529293A/ja not_active Ceased
- 2010-05-21 CA CA2761121A patent/CA2761121A1/en not_active Abandoned
- 2010-05-21 EP EP10786562.8A patent/EP2440570B1/en not_active Not-in-force
-
2012
- 2012-09-17 US US13/621,618 patent/US8476237B2/en active Active
- 2012-09-17 US US13/621,597 patent/US8551943B2/en active Active
- 2012-12-04 US US13/693,507 patent/US8563506B2/en active Active
-
2013
- 2013-08-30 US US14/015,438 patent/US8871708B2/en active Active - Reinstated
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