ES2743919T3 - Péptido de penetración celular, conjugado que comprende el mismo y composición que comprende el conjugado - Google Patents
Péptido de penetración celular, conjugado que comprende el mismo y composición que comprende el conjugado Download PDFInfo
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- ES2743919T3 ES2743919T3 ES13839102T ES13839102T ES2743919T3 ES 2743919 T3 ES2743919 T3 ES 2743919T3 ES 13839102 T ES13839102 T ES 13839102T ES 13839102 T ES13839102 T ES 13839102T ES 2743919 T3 ES2743919 T3 ES 2743919T3
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- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
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- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/86—Products or compounds obtained by genetic engineering
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/10—Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
- C07K2319/21—Fusion polypeptide containing a tag with affinity for a non-protein ligand containing a His-tag
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/60—Fusion polypeptide containing spectroscopic/fluorescent detection, e.g. green fluorescent protein [GFP]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
- C12Y207/07—Nucleotidyltransferases (2.7.7)
- C12Y207/07049—RNA-directed DNA polymerase (2.7.7.49), i.e. telomerase or reverse-transcriptase
Landscapes
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- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
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- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
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- Immunology (AREA)
- Biophysics (AREA)
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- Food Science & Technology (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Birds (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- Dermatology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20120104144 | 2012-09-19 | ||
| KR20120109216 | 2012-09-28 | ||
| KR20130017046 | 2013-02-18 | ||
| KR20130017169 | 2013-02-18 | ||
| PCT/KR2013/008445 WO2014046481A1 (ko) | 2012-09-19 | 2013-09-17 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
Publications (1)
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| ES2743919T3 true ES2743919T3 (es) | 2020-02-21 |
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| ES13839102T Active ES2743919T3 (es) | 2012-09-19 | 2013-09-17 | Péptido de penetración celular, conjugado que comprende el mismo y composición que comprende el conjugado |
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| US (1) | US9631184B2 (OSRAM) |
| EP (1) | EP2899199B1 (OSRAM) |
| JP (1) | JP6510410B2 (OSRAM) |
| KR (1) | KR102201430B1 (OSRAM) |
| CN (3) | CN110064056B (OSRAM) |
| ES (1) | ES2743919T3 (OSRAM) |
| TW (1) | TWI598441B (OSRAM) |
| WO (1) | WO2014046481A1 (OSRAM) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| ES3046661T3 (en) | 2012-05-11 | 2025-12-02 | Gemvax & Kael Co Ltd | Anti-inflammatory peptides and composition comprising the same |
| KR101997756B1 (ko) | 2012-05-11 | 2019-07-08 | 주식회사 젬백스앤카엘 | 패혈증 예방 또는 치료용 조성물 |
| CN104822698B (zh) | 2012-07-11 | 2018-08-10 | 珍白斯凯尔有限公司 | 细胞穿透肽以及包含该肽的缀合物和组合物 |
| US20150125438A1 (en) | 2012-07-20 | 2015-05-07 | Sang Jae Kim | Anti-Inflammatory Peptides and Composition Comprising the Same |
| KR102201429B1 (ko) | 2012-09-19 | 2021-01-12 | 주식회사 젬백스앤카엘 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
| EP4230644A3 (en) | 2012-09-19 | 2024-04-24 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| KR102258864B1 (ko) | 2013-04-19 | 2021-06-01 | 주식회사 젬백스앤카엘 | 허혈성 손상 치료 및 예방용 조성물 |
| BR112015030627A2 (pt) | 2013-06-07 | 2017-07-25 | Gemvax & Kael Co Ltd | marcadores biológicos úteis na imunoterapia contra o câncer |
| KR20160039152A (ko) | 2013-06-21 | 2016-04-08 | 주식회사 젬백스앤카엘 | 호르몬 분비 조절제, 이를 포함하는 조성물, 및 이를 사용한 호르몬 분비 조절 방법 |
| US9757473B2 (en) * | 2013-07-12 | 2017-09-12 | Gemvax & Kael Co., Ltd. | Cell-penetrating peptide and conjugate comprising same |
| EP3061459B1 (en) | 2013-10-23 | 2019-12-11 | Gemvax & Kael Co., Ltd. | Composition for treating and preventing benign prostatic hyperplasia |
| JP6553605B2 (ja) | 2013-11-22 | 2019-07-31 | ジェムバックス アンド カエル カンパニー，リミティド | 血管新生抑制活性を有するペプチド、及びそれを含む組成物 |
| US11058744B2 (en) | 2013-12-17 | 2021-07-13 | Gemvax & Kael Co., Ltd. | Composition for treating prostate cancer |
| US9937240B2 (en) | 2014-04-11 | 2018-04-10 | Gemvax & Kael Co., Ltd. | Peptide having fibrosis inhibitory activity and composition containing same |
| WO2015167067A1 (ko) | 2014-04-30 | 2015-11-05 | 주식회사 카엘젬백스 | 장기, 조직 또는 세포 이식용 조성물, 키트 및 이식 방법 |
| KR102413243B1 (ko) | 2014-12-23 | 2022-06-27 | 주식회사 젬백스앤카엘 | 안질환 치료 펩티드 및 이를 포함하는 안질환 치료용 조성물 |
| WO2016137162A1 (ko) | 2015-02-27 | 2016-09-01 | 주식회사 젬백스앤카엘 | 청력 손상 방어용 펩타이드 및 이를 포함하는 조성물 |
| ES2879641T3 (es) | 2015-05-26 | 2021-11-22 | Gemvax & Kael Co Ltd | Octapéptidos antiinflamatorias, antifibróticos y cicatrizantes de heridas y las composiciones que los contienen |
| US11015179B2 (en) | 2015-07-02 | 2021-05-25 | Gemvax & Kael Co., Ltd. | Peptide having anti-viral effect and composition containing same |
| CN113476589A (zh) * | 2015-11-03 | 2021-10-08 | 珍白斯凯尔有限公司 | 肽在制造用于治疗神经退行性疾病的组合物中的用途 |
| KR101661912B1 (ko) | 2016-01-29 | 2016-10-04 | (주)넥스젠바이오텍 | 녹색형광단백질-인간 상피세포재생인자 융합단백질을 유효성분으로 포함하는 주름 개선 및 항노화 화장료 조성물 |
| KR20180123512A (ko) | 2016-04-07 | 2018-11-16 | 주식회사 젬백스앤카엘 | 텔로머라제 활성 증가 및 텔로미어 연장 효능을 가지는 펩티드 및 이를 포함하는 조성물 |
| WO2017180587A2 (en) | 2016-04-11 | 2017-10-19 | Obsidian Therapeutics, Inc. | Regulated biocircuit systems |
| WO2019241315A1 (en) | 2018-06-12 | 2019-12-19 | Obsidian Therapeutics, Inc. | Pde5 derived regulatory constructs and methods of use in immunotherapy |
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| US6610839B1 (en) * | 1997-08-14 | 2003-08-26 | Geron Corporation | Promoter for telomerase reverse transcriptase |
| NZ334709A (en) * | 1996-10-01 | 2001-06-29 | Univ Technology Corp | Detection of hTRT activity or expression and use in the treatment of cancer |
| US7030211B1 (en) | 1998-07-08 | 2006-04-18 | Gemvax As | Antigenic peptides derived from telomerase |
| GB0112342D0 (en) * | 2001-05-21 | 2001-07-11 | Norsk Hydro As | Polypeptides |
| US20030143228A1 (en) * | 2001-10-29 | 2003-07-31 | Baylor College Of Medicine | Human telomerase reverse transcriptase as a class-II restricted tumor-associated antigen |
| US7294708B2 (en) * | 2002-05-31 | 2007-11-13 | Beijing Institute Of Biotechnology | Telomerase reverse transcriptase fragments and uses thereof |
| JP2009519033A (ja) | 2005-12-16 | 2009-05-14 | ディアト | 核酸を細胞に送達するための細胞貫通ペプチド結合体 |
| EP1991560B1 (en) | 2006-02-20 | 2018-04-04 | Ewha University-Industry Collaboration Foundation | Peptide having cell membrane penetrating activity |
| KR20090103957A (ko) * | 2007-01-29 | 2009-10-01 | 주식회사 프로셀제약 | 신규한 거대분자 전달 도메인 및 이의 동정 방법 및 용도 |
| EP1994942A1 (en) * | 2007-05-25 | 2008-11-26 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Pharmaceutical compositions comprising telomerase, and uses thereof |
| SI2310044T1 (sl) * | 2008-06-16 | 2017-03-31 | Mediolanum Farmaceutici S.P.A. | Proti-tumorska imunoterapija |
| ES2334315B1 (es) * | 2008-07-29 | 2011-02-28 | Universitat Pompeu Fabra | Peptidos con capacidad de penetracion celular y sus usos. |
| WO2010037395A2 (en) * | 2008-10-01 | 2010-04-08 | Dako Denmark A/S | Mhc multimers in cancer vaccines and immune monitoring |
| KR101169030B1 (ko) | 2009-01-21 | 2012-07-26 | 애니젠 주식회사 | 신규한 세포막 투과 도메인 및 이를 포함하는 세포내 전달 시스템 |
| JP5653214B2 (ja) | 2009-05-20 | 2015-01-14 | 東レ株式会社 | 細胞膜透過性ペプチド |
| US9657068B2 (en) * | 2010-02-16 | 2017-05-23 | Ultimovacs As | Telomerase polypeptide vaccine for treating cancer |
| KR101263212B1 (ko) | 2010-05-28 | 2013-05-10 | 성신여자대학교 산학협력단 | 신규한 세포막 투과성 펩타이드 및 그의 용도 |
| WO2011150494A1 (en) * | 2010-05-30 | 2011-12-08 | The Governing Council Of The University Of Toronto | Mitochondrial penetrating peptides as carriers for anticancer compounds |
| KR101348284B1 (ko) * | 2010-09-09 | 2014-01-03 | 주식회사 나이벡 | 인간 유래 세포 투과성 펩타이드와 생리활성 펩타이드 결합체 및 그 용도 |
| ES3046661T3 (en) | 2012-05-11 | 2025-12-02 | Gemvax & Kael Co Ltd | Anti-inflammatory peptides and composition comprising the same |
| CN104822698B (zh) | 2012-07-11 | 2018-08-10 | 珍白斯凯尔有限公司 | 细胞穿透肽以及包含该肽的缀合物和组合物 |
| KR102201429B1 (ko) | 2012-09-19 | 2021-01-12 | 주식회사 젬백스앤카엘 | 세포 투과성 펩티드, 그를 포함한 컨쥬게이트 및 그를 포함한 조성물 |
| EP4230644A3 (en) | 2012-09-19 | 2024-04-24 | Gemvax & Kael Co., Ltd. | Cell penetrating peptide, conjugate comprising same, and composition comprising conjugate |
| KR101778244B1 (ko) | 2014-05-13 | 2017-09-26 | 한양대학교 산학협력단 | 세포 투과성 펩티드 및 이를 이용한 생물학적 활성 물질의 전달방법 |
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| CN110028554A (zh) | 2019-07-19 |
| WO2014046481A1 (ko) | 2014-03-27 |
| JP6510410B2 (ja) | 2019-05-08 |
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| US9631184B2 (en) | 2017-04-25 |
| CN110064056A (zh) | 2019-07-30 |
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| EP2899199B1 (en) | 2019-07-03 |
| EP2899199A1 (en) | 2015-07-29 |
| CN110064056B (zh) | 2022-10-28 |
| CN104768967B (zh) | 2019-02-15 |
| CN104768967A (zh) | 2015-07-08 |
| EP2899199A4 (en) | 2016-06-15 |
| US20160002613A1 (en) | 2016-01-07 |
| TWI598441B (zh) | 2017-09-11 |
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